| 1. |
2024
Gene set correlation enrichment analysis for interpreting and annotating gene expression profiles
. Nucleic Acids Research
.2024
;(52)
|
|
| 2. |
2024
Chia-Hwa Lee,Kai-Wen Hsu,Yao-Yu Hsieh,Wei-Ting Li,Yuqing Long,Chun-Yu Lin and Shu-Huey Chen.
Unveiling IL6R and MYC as Targeting Biomarkers in Imatinib-Resistant Chronic Myeloid Leukemia Through Advanced NI-ADS v2 Detection
. Cells
.2024
;(13):616
|
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| 3. |
2024
Peiyu Wang,Renwu Zhou, Rusen Zhou, Shuo Feng, Liqian Zhao,Wenshao Li, Jinyong Lin, Aleksandra Rajapakse, Chia-Hwa Lee, Frank B Furnari, Antony W Burgess, Jennifer H Gunter, Gang Liu, Kostya Ken Ostrikov, Derek J Richard, Fiona Simpson, Xiaofeng Dai, Erik W Thompson.
Epidermal Growth Factor potentiates EGFR(Y992/1173)-mediated therapeutic response of triple negative breast cancer cells to cold atmospheric plasma-activated medium
. Redox Biology
.2024
;(69):102976
|
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| 4. |
2023
Syahru Agung Setiawan,Winston Zhenhao Liu,Pei-Wei Weng,Chia Hwa Lee,Vijesh Kumar Yadav,Mardiah Suci Hardianti, Chi-Tai Yeh, Tsu-Yi Chao.
Synergistic disruption of BTK and BCL-2 causes apoptosis while inducing ferroptosis in double-hit lymphoma
. European Journal of Pharmacology
.2023
;(943):175526
|
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| 5. |
2023
Hsin-Hua Chen,Chun-Wei Hsueh,Chia-Hwa Lee,Ting-Yi Hao,Tzu-Ying Tu,Lan-Yun Chang, Jih-Chin Lee, Chun-Yu Lin.
SWEET: a single-sample network inference method for deciphering individual features in disease
. Briefings in Bioinformatics
.2023
;(24):1-15
|
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| 6. |
2022
Ming-Lin Tsai,Chia-Hwa Lee,Li-Chi Huang,Yu-Hsin Chen,Wei-Ni Liu,Chun-Yu Lin,Kai-Wen Hsu,Ai-Wei Lee,Ching-Ling Lin.
CRISPR-mediated knockout of VEGFR2/KDR inhibits cell growth in a squamous thyroid cancer cell line
. FEBS Open Bio
.2022
;(12)
|
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| 7. |
2022
Hou-Hsien Liu,Chia-Hwa Lee,Yi-Chen Hsieh,Jia-Huei Zheng,Yun-Ru Liu,Chia-Hsuan Chang, Er-Chieh Cho.
Mitochondrial Factor C20orf7 Facilitates the EMT-Mediated Cancer Cell Migration and the Proliferation of Colon Cancer In Vitro and In Vivo
. Genes
.2022
;(13):2111-2123
|
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| 8. |
2021
Ching-Ling Lin,Ming-Lin Tsai,Yu-hsin Chen,Wei-Ni Liu,Chun-Yu Lin,Kai-Wen Hsu, Chien-Yu Huang, Yu-Jia Chang, Po-Li Wei, Shu-Huey Chen, Li-Chi Huang and Chia-Hwa Lee.
Platelet-derived growth factor receptor-α subunit targeting suppresses metastasis in advanced thyroid cancer in vitro and in vivo
. Biomolecules & Therapeutics
.2021
|
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| 9. |
2021
Hou-Hsien Liu,Chia-Hwa Lee,Yi-Chen Hsieh,Duen-Wei Hsu,Er-Chieh Cho.
Multiple myeloma driving factor WHSC1 is a transcription target of oncogene HMGA2 that facilitates colon cancer proliferation and metastasis
. Biochemical and Biophysical Research Communications
.2021
|
|
| 10. |
2020
Shu-Huey Chen,Yao-Yu Hsieh,Huey-En Tzeng,Chun-Yu Lin,Kai-Wen Hsu,Yun-Shan Chiang, Su-Mei Lin, Ming-Jang Su, Wen-Shyang Hsieh, Chia-Hwa Lee.
ABL genomic editing sufficiently abolishes oncogenesis of human chronic myeloid leukemia cells in vitro and in vivo
. Cancers
.2020
;(12):1399-1423
|
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| 11. |
2020
Yi-Hsuan Chuang,Chia-Hwa Lee,Chun-Yu Lin,Chia-Lin Liu,Sing-Han Huang,Jung-Yu Lee, Yi-Yuan Chiu, Jih‐Chin Lee, Jinn-Moon Yang.
An integrated genomic strategy to identify CHRNB4 as a diagnostic/prognostic biomarker for targeted therapy in head and neck cancer
. Cancers
.2020
;(12):1324-1347
|
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| 12. |
2019
Jie‐Ying Wu,Ya‐Ting Chang,Ying‐Chin Lin,Chia‐Hwa Lee,El‐Wui Loh,Mei‐Yi Wu, Yu‐Sheng Chang, Ka‐Wai Tam.
Efficacy and Safety of Lesinurad in Patients with Hyperuricemia Associated with Gout: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
. Pharmacotherapy
.2019
;(38):1106-1119
|
|
| 13. |
2019
Ching-Ling Lin,Ming-Lin Tsai,Chun-Yu Lin,Kai-Wen Hsu,Wen-Shyang Hsieh,Wei-Ming Chi, Li-Chi Huang, Chia-Hwa Lee.
HDAC1 and HDAC2 Double Knockout Triggers Cell Apoptosis in Advanced Thyroid Cancer.
. International Journal of Molecular Sciences
.2019
;(20):454-467
|
|
| 14. |
2019
Shu-Huey Chen,Jyh-Ming Chow,Yao-Yu Hsieh,Chun-Yu Lin,Kai-Wen Hsu,Wen-Shyang Hsieh, Wei-Ming Chi, Beished M. Shabangu, Chia-Hwa Lee.
HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells
. International Journal of Molecular Sciences
.2019
;(20):2271-2287
|
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| 15. |
2019
Lin Chun-Yu,Lee Chia-Hwa,Chuang Yi-Hsuan,Lee Jung-Yu,Chiu Yi-Yuan,Wu Lee Yan-Hwa, Ho Yuan-Soon, Yang Jinn-Moon.
Membrane protein-regulated networks across human cancers
. Nature Communications
.2019
;(10):3131-3148
|
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| 16. |
2018
Precious Takondwa Makondi, Chia-Hwa Lee,Chien-Yu Huang,Chi-Ming Chu,Yu-Jia Chang,Po-Li Wei.
Prediction of novel target genes and pathways involved in bevacizumab-resistant colorectal cancer
. PLoS One
.2018
;(13)
|
|
| 17. |
2018
Chien-Yu Huang,Chia-Hwa Lee,Chao-Chiang Tu,Chih-Hsiung Wu,Ming-Te Huang,Po-Li Wei, Yu-Jia Chang.
Glucose-regulated protein 94 mediates progression and metastasis of esophageal squamous cell carcinoma via mitochondrial function and the NFkb/COX-2/VEGF axis
. Oncotarget
.2018
;(9):9425-9441
|
|
| 18. |
2018
Huang YH,Chen C,Lee CH,Loh EW,Tam KW.
Wound Closure after thyroid and Parathyroid surgery: a Meta-analysis of randoMized Controlled trials
. Scandinavian Journal of Surgery
.2018
;(1457496918798203):1-8
|
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| 19. |
2018
Li-Chi Huang,Ka-Wai Tam,Wei-Ni Liu,Chun-Yu Lin,Kai-Wen Hsu,Wen-Shyang Hsieh, Wei-Ming Chi, Ai-Wei Lee, Jinn-Moon Yang, Ching-Ling Lin, Chia-Hwa Lee.
CRISPR/Cas9 genome editing of Epidermal Growth Factor Receptor sufficiently abolished oncogenicity in Anaplastic Thyroid cancer.
. Disease Markers
.2018
;(2018)
|
|
| 20. |
2018
Kai-Wen Hsu,Chien-Yu Huang,Ka-Wai Tam,Chun-Yu Lin,Li-Chi Huang,Ching-Ling Lin, Wen-Shyang Hsieh, Wei-Ming Chi, Yu-Jia Chang, Po-Li Wei, Shou-Tung Chen, Chia-Hwa Lee.
The Application of Non-Invasive Apoptosis Detection Sensor (NIADS) on Histone Deacetylation Inhibitor (HDACi)-Induced Breast Cancer Cell Death
. International Journal of Molecular Sciences
.2018
;(19)
|
|
| 21. |
2018
Lawrence Chen,Yi-Hsiu Wu,Chia-Hwa Lee,Hsin-An Chen,El-Wui Loh,Ka-Wai Tam.
Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma with Clinically Uninvolved Central Neck Lymph Nodes: A Systematic Review and Meta-analysis
. World Journal of Surgery
.2018
;(42):2846-2857
|
|
| 22. |
2017
Chin-Sheng Hung,Chien-Yu Huang,Chia-Hwa Lee,Wei-Yu Chen,Ming- Te Huang,Po-Li Wei, Yu-Jia Chang.
IGFBP2 plays an important role in heat shock protein 27-mediated cancer progression and metastasis.
. Oncotarget
.2017
;(8):54978-54992
|
|
| 23. |
2017
Yi-Chen Hsieh,Er-Chieh Cho,Shih-Hsin Tu,Chih-Hsiung Wu,Chin-Sheng Hung,Mao-Chih Hsieh, Chien-Tien Su, Yun-Ru Liu, Chia-Hwa Lee, Yuan-Soon Ho, Hung-Yi Chiou.
MSH2 rs2303425 Polymorphism is Associated with Early-Onset Breast Cancer in Taiwan
. Annals of Surgical Oncology.
.2017
;(24):603-610
|
|
| 24. |
2017
Shih-Hsin Tu,Yi-Chen Hsieh,Li-Chi Huang,Chun-Yu Lin,Kai-Wen Hsu,Wen-Shyang Hsieh, Wei-Ming Chi, Chia-Hwa Lee.
A Rapid and Quantitative Method to Detect Human Circulating Tumor Cells in a Preclinical Animal Model.
. BMC CANCER
.2017
;(17):440-450
|
|
| 25. |
2017
Jen-Wei Liu,Chieh-feng Chen,El-Wui Loh,Chun-Cheng Chu,Mu-Yi Wang,Hsin-Ju Ouyang, Ya-Ting Chang, Wei-Zhan Zhuang, Ching-Wen Chou, Der-Jr Huang, Chia-Hwa Lee, Yun Yen, Ka-Wai Tam.
Tyrosine kinase inhibitors for advanced or metastatic thyroid cancer: a meta-analysis of randomized controlled trials.
. Curr Med Res Opin
.2017
|
|
| 26. |
2017
Li-Chi Huang,Ching-Ling Lin,Jia-Zheng Qiu,Chun-Yu Lin,Kai-Wen Hsu,Ka-Wai Tam, Jung-Yu Lee, Jinn-Moon Yang, Chia-Hwa Lee.
Nicotinic Acetylcholine Receptor Subtype Alpha-9 Mediates Triple-Negative Breast Cancers Based on a Spontaneous Pulmonary Metastasis Mouse Model.
. Frontiers in Cellular Neuroscience.
.2017
;(11)
|
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| 27. |
2017
Ka-Wai Tam,Chi-Tang Ho,Shih-Hsin Tu,Wen-Jui Lee,Ching-Shui Huang,Ching-Shyang Chen, Chih-Hsiung Wu, Chia-Hwa Lee, Yuan-Soon Ho.
α-Tocopherol Succinate Enhances Pterostilbene Anti-Tumor Activity in Human Breast Cancer Cells In Vivo and In Vitro.
. Oncotarget
.2017
;(9):4593-4606
|
|
| 28. |
2014
Yi-Chen Hsieh,Chia-Hwa Lee,Shih-Hsin Tu,Chih-Hsiung Wu,Chin-Sheng Hung,Mao-Chih Hsieh, Ching-Wen Chuang.
CHRNA9 polymorphisms and smoking exposure synergize to increase the risk of breast cancer in Taiwan.
. Carcinogenesis
.2014
;(35):2520-2525
|
|
| 29. |
2013
Ka-Wai Tam,Chi-Tang Ho,Wen-Jui Lee,Shih-Hsin Tu,Ching-Shui Huang,Ching-Shyang Chen, Chia-Hwa Lee, Chih-Hsiung Wu, Yuan-Soon Ho.
Alteration of α-tocopherol-associated protein (TAP) expression in human breast epithelial cells during breast cancer development.
. Food Chemistry
.2013
;(138):1015-1021
|
|
| 30. |
2013
Li-Ching Chen,Shih-Hsin Tu,Ching-Shui Huang,Ching-Shyang Chen,Chi-Tang Ho,Chia-Hwa Lee, Hui-Wen Chang, Chien-Hsi Chang, Chih-Hsiung Wu, Wen-Sen Lee, Yuan-Soon Ho.
Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin signaling pathway.
. Breast Cancer Research and Treatment
.2013
|
|
| 31. |
2012
Tu SH,Ku CY,Ho CT,Chen CS,Huang CS,Lee CH, Chen LC, Pan MH, Chang HW, Chang CH, Chang YJ, Wei PL, Wu CH, Ho YS.
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced alpha9-nicotinic acetylcholine receptor upregulation in human breast cancer cells.
. Molecular Nutrition and Food Research
.2012
;(55):455-466
|
|
| 32. |
2012
Le CH,Chang YC,Chen CS,Tu SH,Wang YJ,Chen LC, Chang YJ, Wei PL, Chang HW, Chang CH, Huang CS, Wu CH, Ho YS.
Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces alpha9-nicotinic acetylcholine receptor expression in human breast cancer cell.
. Breast Cancer Research and Treatment
.2012
;(129):331-345
|
|
| 33. |
2012
Ho YS,Lee CH,Wu CH.
Smoking-induced human breast cancer formation through induction of alpha9-nicotinic acetylcholine receptor.
. Formosan Journal of Surgery
.2012
;(44):47-52
|
|
| 34. |
2011
Lee CH,Wu CH,Ho YS.
From Smoking to Cancers: Novel Targets to Neuronal Nicotinic Acetylcholine Receptors.
. Journal of Oncology.
.2011
;(2011):693424
|
|
| 35. |
2011
Wu CH,Lee CH,Ho YS.
Nicotinic acetylcholine receptor-based blockade: Applications of molecular target for cancer therapy.
. Clinical Cancer Research
.2011
;(17):3533-3541
|
|
| 36. |
2011
Chen CS,Lee CH,Hsieh CD,Ho CT,Pan MH,Huang CS, Tu SH, Wang YJ, Chen LC, Chang YJ, Wei PL, Yang YY, Wu CH, Ho YS.
Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins.
. Breast Cancer Research and Treatment
.2011
;(125):73-87
|
|
| 37. |
2010
Lee CH,Huang CS,Chen CS,Tu SH,Wang YJ,Chang YJ, Tam KW, Wei PL, Cheng TC, Chu JS, Chen LC, Wu CH, Ho YS.
Overexpression and activation of the alpha9-nicotinic receptor during tumorigenesis in human breast epithelial cells.
. Journal of the National Cancer Institute
.2010
;(102):1322-1335
|
|
| 38. |
2010
Tu SH,Chang CC,Chen CS,Tam KW,Wang YJ,Lee CH, Lin HW, Huang TC, Chu CS, Shih NY, Chen LC, Leu SJ, Ho YS, Wu CH.
Increased expression of enolase alpha in human breast cancer confers tamoxifen resistance in human breast cancer cells.
. Breast Cancer Research and Treatment
.2010
;(121):539-553
|
|
| 39. |
2010
Huang CS,Lee YR,Chen CS,Tu SH,Wang YJ,Lee CH, Chen LC, Chang HW, Chang CH, Su CM, Wu CH, Ho YS.
Long-term ethanol exposure causes human liver cancer cells to become resistant to mitomycin C treatment through the inactivation of bad-mediated apoptosis.
. Molecular Carcinogenesis
.2010
;(49):728-738
|
|
| 40. |
2009
Wei PL,Chang YJ,Ho YS,Lee CH,Yang YY,An J, Lin SY.
Tobacco-specific carcinogen enhances colon cancer cell migration through alpha7-nicotinic acetylcholine receptor.
. Annals of Surgery
.2009
;(249):978-985
|
|
| 41. |
2009
Wu CH,Ho YS,Tsai CY,Wang YJ,Tseng H,Wei PL, Lee CH, Liu RS, Lin SY.
In vitro and in vivo study of phloretin-induced apoptosis in human liver cancer cells involving inhibition of type II glucose transporter.
. International Journal of Cancer
.2009
;(124):2210-2219
|
|
| 42. |
2009
Yang KC,Tsai CY,Wang YJ,Wei PL,Lee CH,Chen JH, Wu CH, Ho YS.
Apple polyphenol phloretin potentiates the anticancer actions of paclitaxel through induction of apoptosis in human hep G2 cells.
. Molecular Carcinogenesis
.2009
;(48):420-431
|
|
| 43. |
2009
Wang X,Ni J,Hsu CL,Johnykutty S,Tang P,Ho YS, Lee CH, Yeh S.
Reduced expression of tocopherol-associated protein (TAP/Sec14L2) in human breast cancer.
. Cancer Investigation
.2009
;(27):971-977
|
|
| 44. |
2008
Huang CS,Ho WL,Lee WS,Sheu MT,Wang YJ,Tu SH, Chen RJ, Chu JS, Chen LC, Lee CH, Tseng H, Ho YS, Wu CH.
SP1-regulated p27/Kip1 gene expression is involved in terbinafine-induced human A431 cancer cell differentiation: an in vitro and in vivo study.
. Biochemical Pharmacology
.2008
;(75):1783-1796
|
|
| 45. |
2007
Chou YH,Ho YS,Wu CC,Chai CY,Chen SC,Lee CH, Tsai PS, Wu CH.
Tubulozole-induced G2/M cell cycle arrest in human colon cancer cells through formation of microtubule polymerization mediated by ERK1/2 and Chk1 kinase activation.
. Food Chemistry and Toxicology
.2007
;(45):1356-1367
|
|
| 46. |
2006
Yang KC,Wu CC,Wu CH,Chen JH,Chu CH,Chen CH, Chou YH, Wang YJ, Lee WS, Tseng H, Lin SY, Lee CH, Ho YS.
Involvement of proapoptotic Bcl-2 family members in terbinafine-induced mitochondrial dysfunction and apoptosis in HL60 cells.
. Food Chemistry and Toxicology
.2006
;(44):214-226
|
|
| 47. |
2005
Ho YS,Wu CH,Chou HM,Wang YJ,Tseng H,Chen CH, Chen LC, Lee CH, Lin SY.
Molecular mechanisms of econazole-induced toxicity on human colon cancer cells: G0/G1 cell cycle arrest and caspase 8-independent apoptotic signaling pathways.
. Food Chemistry and Toxicology
.2005
;(43):1483-1495
|
|
| 48. |
2005
Ho YS,Chen CH,Wang YJ,Pestell RG,Albanese C,Chen RJ, Chang MC, Jeng JH, Lin SY, Chen LC, Lee CH, Tso WL, Lai YC, Wu CH.
Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation.
. Toxicology and Applied Pharmacology
.2005
;(205):133-148
|
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