馮博皓(Feng, Po-Hao) 副教授

Email
fengpohao@tmu.edu.tw
現   職
內科學科 副教授

學經歷

學 歷

畢業學校與學位[修業時間]
長庚大學臨床醫學研究所 博士
中國醫藥大學醫學系 學士
1994/09~2001/06

本校學術經歷

任職單位與職稱[起迄時間]
內科學科副教授
2020/02/01~
內科學科助理教授
2019/01/16~2020/01/31
內科學科助理教授
2014/08/01~2018/12/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
林口長庚醫院主治醫師
2002/07/26~2013/06/10

專長與研究領域

學門領域
學術專長
醫學
Medical Science
免疫學
免疫學
Lung cancer research
Lung cancer research

論文著作

清冊下載


1. 2024 Shang-Yang Lin,Cheng-Yu Tsai,Arnab Majumdar, Yu-Hsuan Ho, Yu-Wen Huang,Chun-Kai Kao, Shang-Min Yeh, Wen-Hua Hsu, Yi-Chun Kuan, Kang-Yun Lee, Po-Hao Feng, Chien-Hua Tseng, Kuan-Yuan Chen, Jiunn-Horng Kang, Hsin-Chien Lee, Cheng-Jung Wu, Wen-Te Liu. Combining wireless radar sleep monitoring device with deep machine learning techniques to assess obstructive sleep apnea severity . J Clin Sleep Med . .2024

2. 2024 Wang-Da Liu,Po-Hao Feng,Chien-Yu Cheng,Chun-Liang Chou,Chih-Hsin Lee,Min-Chi Lu, Po-Yu Liu, Mei-Hui Lee, Chun-Hsing Liao, Mei-Chuan Chen, Cheng-Pin Chen, Shang-Fu Hsu, Yu-Tien Tzeng, Yi-Chun Lin, Tsong-Yih Ou, Albert Qin, Chan-Yen Tsai, Weichung Joe Shih, Kang-Yun Lee, Wang-Huei Sheng. A Phase 3, Randomized, Controlled Trial Evaluating the Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Moderate COVID-19 . Infect Dis Ther. .2024

3. 2024 Kuan-Yuan Chen, Wei-Lun Sun,Sheng-Ming Wu,Po-Hao Feng,Chiou-Feng Lin,Tzu-Tao Chen, Yueh-Hsun Lu, Shu-Chuan Ho, Yueh-Hsi Chen, Kang-Yun Lee. Reduced Tolerogenic Program Death-Ligand 1-Expressing Conventional Type 1 Dendritic Cells Are Associated with Rapid Decline in Chronic Obstructive Pulmonary Disease . Cells. .2024

4. 2023 Chen KY,Kuo HY,Lee KY,Feng PH,Wu SM,Chuang HC, Chen TT, Sun WL, Tseng CH, Liu WT, Cheng WH, Arnab Majumdar, Marc Stettler, Tsai CY, Ho SC. Associations of the distance-saturation product and low-attenuation area percentage in pulmonary computed tomography with acute exacerbation in patients with chronic obstructive pulmonary disease . Front Med (Lausanne) .2023 ;(9)

5. 2023 Xiao-Yue Chen,Kuan-Yuan Chen,Po-Hao Feng,Kang-Yun Lee,Yu-Ting Fang,You-Yin Chen , Yu-Chun Lo , Pankaj K. Bhavsar , Kian Fan Chung , Hsiao-Chi Chuang. YAP-regulated type II alveolar epithelial cell differentiation mediated by human umbilical cord-derived mesenchymal stem cells in acute respiratory distress syndrome. . Biomed Pharmacother . .2023 ;(159)

6. 2023 Wen-Hua Hsu,Cheng-Chang Yang,Cheng-Yu Tsai,Arnab Majumdar,Kang-Yun Lee,Po-Hao Feng, Chien-Hua Tseng, Kuan-Yuan Chen, Jiunn-Horng Kang, Hsin-Chien Lee, Cheng-Jung Wu, Yi-Chun Kuan, Wen-Te Liu. Association of Low Arousal Threshold Obstructive Sleep Apnea Manifestations with Body Fat and Water Distribution . Life(Basel) .2023 ;(13):1218-1231

7. 2023 Cheng-Yu Tsai,Huei-Tyng Huang,Ming Liu,Wun-Hao Cheng,Wen-Hua Hsu,Yi-Chun Kuan, Arnab Majumdar, Kang-Yun Lee, Po-Hao Feng, Chien-Hua Tseng, Kuan-Yuan Chen, Jiunn-Horng Kang, Hsin-Chien Lee, Cheng-Jung Wu, Wen-Te Liu. Associations between air pollution, intracellular-to-extracellular water distribution, and obstructive sleep apnea manifestations . Front Public Health .2023 ;(11):1175203-1175213

8. 2023 Chih-Fan Kuo,Cheng-Yu Tsai,Wun-Hao Cheng,Wen-Hua Hs,Arnab Majumdar,Marc Stettler 4, Kang-Yun Lee 5 8, Yi-Chun Kuan 9 10 11 12, Po-Hao Feng 5 8, Chien-Hua Tseng 5 8, KuanYuan Chen, Jiunn-Horng Kang, Hsin-Chien Lee, Cheng-Jung Wu, Wen-Te Liu. Machine learning approaches for predicting sleep arousal response based on heart rate variability, oxygen saturation, and body profiles . Digit Health . .2023 ;(9)

9. 2023 Cheng-Yu Tsai,Ming Liu,Huei-Tyng Huang,Wen-Hua Hsu,Yi-Chun Kuan,Arnab Majumdar, Kang-Yun Lee, Po-Hao Feng, Chien-Hua Tseng, Kuan-Yuan Chen, Jiunn-Horng Kang, Hsin-Chien Lee, Cheng-Jung Wu, Wen-Te Liu. Association between air pollutant exposure, body water distribution and sleep disorder indices in individuals with low-arousal-threshold obstructive sleep apnoea . BMJ Open Respir Res. .2023 ;(10):e001802-e001812

10. 2022 Nguyen Van Hiep,Sun WL,Feng PH,Lin CW,Chen KY,Luo CS, Le Ngoc Dung, Hoang Van Quyet, Wu SM, Lee KY. Heparin binding epidermal growth factor-like growth factor is a prognostic marker correlated with levels of macrophages infiltrated in lung adenocarcinoma . Front Oncol . .2022

11. 2022 Bai Geng Hao,Shih Ping Yi,Chen Shih Yen,Hsieh Kai Sheng,Chou Cheng Che,Feng Po Hao,Kong Shu Sing,Lin Wen Chuan,Lu Meng Che,Bai Geng Hao,Shih Ping Yi,Chen Shih Yen,Hsieh Kai Sheng,Chou Cheng Che,Feng Po Hao,Kong Shu Sing,Lin Wen Chuan,Lu Meng Che. Clinical features and characteristics of pediatric patients with COVID-19 infection: Experiences in a Tertiary Taiwan Hospital . Medicine .2022 ;(101):E30157-E30157

12. 2022 Lu LY,Feng PH,Yu MS,Chen MC,Lin AJ, Chen JL, Yu LH*.. Current utilization of interferon alpha for the treatment of coronavirus disease 2019: A comprehensive review . Cytokine Growth Factor Rev. .2022 ;(63):34-43

13. 2022 Lee KY,Wu SM,Kou HY,Chen KY,Chuang HC,Feng PH, Chung KF, Ito K, Chen TT, Sun WL, Liu WT, Tseng CH, Ho SC.. Association of air pollution exposure with exercise-induced oxygen desaturation in COPD . Respir Res .2022 ;(23(1)):1-12

14. 2022 Feng PH,Wang X,Ferrall L,Wu TC,Hung CF. Control of Tumors by Antigen-Specific CD8 + T Cells through PDL1-Targeted Delivery of Antigenic Peptide . J Immunol Res. .2022 ;(2022)

15. 2022 Bamodu OA,Wu SM,Feng PH,Sun WL,Lin CW,Chuang HC, Ho SC, Chen KY, Chen TT, Tseng CH, Liu WT, Lee KY*.. lnc-IL7R Expression Reflects Physiological Pulmonary Function and Its Aberration Is a Putative Indicator of COPD . Biomedicines. .2022 ;(10(4))

16. 2022 Lee KY,Ho SC,Sun WL,Feng PH, Lin CW,Chen KY, Chuang HC, Tseng CH, Chen TT, Wu SM.. Lnc-IL7R alleviates PM 2.5-mediated cellular senescence and apoptosis through EZH2 recruitment in chronic obstructive pulmonary disease . Cell Biol Toxicol. .2022

17. 2022 Tseng PC,Chen CL,Lee KY,Feng PH,Wang YC, Satria RD, Lin CF*.. Epithelial-to-mesenchymal transition hinders interferon-γ-dependent immunosurveillance in lung cancer cells . Cancer Lett. .2022 ;(28)

18. 2022 Wang YC,Lin SW,Wang IJ, Yang CY,Hong C,Sun JR, Feng PH, Lee MH, Shen CF, Lee YT, Cheng CM. Interleukin-6 Test Strip Combined With a Spectrum-Based Optical Reader for Early Recognition of COVID-19 Patients With Risk of Respiratory Failure. . Front Bioeng Biotechnol. .2022 ;(10)

19. 2022 Putri DU,Feng PH,Lin CF,Haryana SM,Soesatyo MHNE, Lee KY, Han CL.. Proteomic networks associated with tumor-educated macrophage polarization and cytotoxicity potentiated by heat-killed tuberculosis . Sci Rep. .2022 ;(12(1))

20. 2022 Huang WT,Yun T,Chew CH,Chen A,Wei PL,Lee KY, Lee HL, Feng PH, Chiou JF, Chen CM, Chen CC.. Microtube Array Membrane Hollow Fiber Assay (MTAM-HFA)-An Accurate and Rapid Potential Companion Diagnostic and Pharmacological Interrogation Solution for Cancer Immunotherapy (PD-1/PD-L1) . Biomolecules. .2022 ;(12(4))

21. 2021 Chen KY,Tseng CH,Feng PH,Sun WL,Ho SC,Lin Cheng Wei,Van Hiep Nguyen,Luo Ching Shan,Tseng Yen Han,Chen Tzu Tao,Liu Wen Te,Lee Kang Yun,Wu Sheng Ming,Chen Kuan Yuan,Tseng Chien Hua,Feng Po Hao,Sun Wei Lun,Ho Shu Chuan,Lin Cheng Wei,Van Hiep Nguyen,Luo Ching Shan,Tseng Yen Han,Chen Tzu Tao,Liu Wen Te,Lee Kang Yun,Wu Sheng Ming. 3-Nitrobenzanthrone promotes malignant transformation in human lung epithelial cells through the epiregulin-signaling pathway . Cell Biology and Toxicology .2021

22. 2021 Chen XY,Feng PH,Han CL,Jheng YT,Wu CD,Chou HC, Chen YY, Wu SM, Lee KY, Kuo HP, Chung KF, Hsiao TC, Chen KY, Ho SC, Chang TY, Chuang HC.. Alveolar epithelial inter-alpha-trypsin inhibitor heavy chain 4 deficiency associated with senescence-regulated apoptosis by air pollution . Environmental Pollution .2021 ;(278)

23. 2021 Chen KY ,Lee KY,Qin A,Luo CS,Yeh YK,Zheng JQ, Chen CM, Tsai CY, Lin S, Liao J, Huang YW, Feng PH*. Clinical Experience with Ropeginterferon Alfa-2b in the Off-Label Use for the Treatment of COVID-19 Patients in Taiwan . Advances in Therapy .2021

24. 2021 Wu SM,Sun WL,Lee KY,Lin CW,Feng PH, Chuang HC, Ho SC, Chen KY, Chen TT, Liu WT, Tseng CH, Bamodu OA.. Determinants of pulmonary emphysema severity in taiwanese patients with chronic obstructive pulmonary disease: An integrated epigenomic and air pollutant analysis . Biomedicines .2021 ;(9)

25. 2021 Chang CM,Feng PH,Wu TH,Alachkar H,Lee KY,Chang WC. Profiling of T Cell Repertoire in SARS-CoV-2-Infected COVID-19 Patients Between Mild Disease and Pneumonia. . J Clin Immunol. .2021 ;(41):1131-1145

26. 2021 Chen TT,Wu SM,Chen KY,Tseng CH,Ho SC,Chuang HC, Feng PH, Liu WT, Han CL, Huang EW, Yeh YK, Lee KY.. Suppressor of variegation 3-9 homologue 1 impairment and neutrophil-skewed systemic inflammation are associated with comorbidities in COPD. . BMC Pulm Med. .2021 ;(21):276

27. 2021 Cheng WL,Feng PH,Lee KY,Chen KY, Sun WL,Van Hiep N, Luo CS, Wu SM.. The Role of EREG/EGFR Pathway in Tumor Progression. . Int J Mol Sci. .2021 ;(22):12828

28. 2021 Bai KJ,Tung NT,Hsiao TC,Chen TL,Chung KF,Ho SC, Tsai CY, Chen JK, Lee CN, Lee KY, Chang CC, Chen TT, Feng PH, Chen KY, Su CL, Thao HNX, Dung HB, Thuy TPC, Lee YL, Chuang HC.. Associations between lung-deposited dose of particulate matter and culture-positive pulmonary tuberculosis pleurisy. . Environ Sci Pollut Res Int. .2021 ;(29):6140-6150

29. 2021 D Planchard, P-H Feng, N Karaseva,S-W Kim, T M Kim, C K Lee, A Poltoratskiy, N Yanagitani, R Marshall, X Huang, P Howarth, P A Jänne, K Kobayashi. Osimertinib plus platinum-pemetrexed in newly diagnosed epidermal growth factor receptor mutation-positive advanced/metastatic non-small-cell lung cancer: safety run-in results from the FLAURA2 study . ESMO Open . .2021

30. 2020 Cheng WL,Chen KY,Lee KY,Feng PH,Wu SM. Nicotinic-nAChR signaling mediates drug resistance in lung cancer. . J Cancer .2020 ;(11):1125-1140

31. 2020 Su BC ,Ting CH,Lee KY,Wu SM, Feng PH,Chan YF, Chen JY. Novel PD-L1 mAb HC16 reveals upregulation of PD-L1 in BAC subtype . Histol Histopathol .2020

32. 2020 Feng PH,Lam B,Tseng SH,Kung YJ,Farmer E,Cheng MA, Hung CF. NKG2D-Fc fusion protein promotes antitumor immunity through the depletion of immunosuppressive cells . Cancer Immunol Immunother .2020 ;(69):2147-2155

33. 2020 Bai KJ,Ho SC,Tsai CY,Chen JK,Lee CN,Lee KY, Chang CC, Chen TT, Feng PH, Chen KY, Su CL, Chuang HC.. Exposure to PM 2.5 is associated with malignant pleural effusion in lung cancer patients . Ecotoxicol Environ Saf. .2020 ;(208)

34. 2020 Chuang HC,Chen YY,Hsiao TC,Chou HC,Kuo HP, Feng PH, Ho SC, Chen JK, Chuang KJ, Lee KY. Alteration in angiotensin-converting enzyme 2 by PM 1 during the development of emphysema in rats . ERJ Open Res. .2020 ;(6)

35. 2020 Wu SM, , , , ,Feng PH,Chuang HC,Ho SC,Fan Chung K,Chen KY, Wu GS, Chen TT, Tseng CH, Liu WT, Lee KY. Impaired lnc-IL7R modulatory mechanism of Toll-like receptors is associated with an exacerbator phenotype of chronic obstructive pulmonary disease . FASEB J .2020 ;(34):13317-13332

36. 2020 Chang CJ,Chiang LL,Chen KY,Feng PH,Su CL,Hsu HS. High-Flow Nasal Cannula versus Noninvasive Positive Pressure Ventilation in Patients with Heart Failure after Extubation: An Observational Cohort Study . Can Respir J .2020 ;(2020)

37. 2019 Lee PL,Lee KY,Cheng TM,Chuang HC,Wu SM,Feng PH, Liu WT, Chen KY, Ho SC. Relationships of Haptoglobin Phenotypes with Systemic Inflammation and the Severity of Chronic Obstructive Pulmonary Disease. . Sci Rep .2019 ;(9):189

38. 2019 Ting CH,Lee KY,Wu SM,Feng PH,Chan YF,Chen YC, Chen JY. FOSB⁻PCDHB13 Axis Disrupts the Microtubule Network in Non-Small Cell Lung Cancer. . Cancers (Basel) .2019 ;(11):pii: E107

39. 2019 Bai KJ,Chuang KJ,Chen JK,Tsai CY,Yang YL,Chang CC, Chen TT, Lee CN, Feng PH, Chen KY, Lee KY, Su CL, Ho SC, Wu SM, Chuang HC.. Alterations by Air Pollution in Inflammation and Metals in Pleural Effusion of Pneumonia Patients . Int J Environ Res Public Health .2019 ;(16):pii: E705

40. 2019 Ho SC,Chuang KJ, Lee KY,Chen JK,Wu SM,Chen TT, Lee CN, Chang CC, Feng PH, Chen KY, Su CL, Tsai CY, Chuang HC. Chronic obstructive pulmonary disease patients have a higher risk of occurrence of pneumonia by air pollution . Sci Total Environ .2019 ;(677):524-529

41. 2018 Feng PH,Chen KY,Huang YC,Lo CS,Wu SM,Chen TT, Lee CN, Yeh CT, Chuang HC, Han CL, Lin CF, Lee WH, Kuo CH, Lee KY. Bevacizumab Reduces S100A9-Positive MDSCs Linked to Intracranial Control in Patients with EGFR-Mutant Lung Adenocarcinoma. . Journal of Thoracic Oncology .2018

42. 2018 Po-Hao Feng,Yin‐Tzu Lin,Chung‐Ming Lo. A machine learning texture model for classifying lung cancer subtypes using preliminary bronchoscopic findings. . Medical Physics .2018 ;(45):5509-5514

43. 2018 Po-Hao, Feng,Tzu-Tao, Chen,Yin-Tzu, Lin,Shang-Yu, Chiang,Chung-Ming, Lo. Classification of lung cancer subtypes based on autofluorescence bronchoscopic pattern recognition: A preliminary study . Computer Methods and Programs in Biomedicine .2018

44. 2018 Chun-Hung Lin,,Wei-Haiang Su,,Ying-Chun Chen,,Po-Hao Feng,Wan-Chen Shen,Jiann-Ruey Ong, Mei-Yi Wu, Chung Shun Wong. Treatment with normobaric or hyperbaric oxygen and its effect on neuropsychometric dysfunction after carbon monoxide poisoning: A systematic review and meta-analysis of randomized controlled trials. . Medicine (Baltimore). .2018

45. 2018 Huang YC ,Shen SM,Liu CY,Pavlidis S,Wang CL,Ko HW, Chung FT, Lin TY, Feng PH, Lee KY, Guo YK, Yang CT, Kuo CS. Impact of prolonged and early bevacizumab treatment on the overall survival of EGFR-mutant and EGFR-wild type nonsquamous non-small cell lung cancer. . Thoracic Cancer .2018

46. 2018 Feng PH. S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: the role of RELB . Oncotarget .2018

47. 2018 Denise Utami Putri,Feng PH,Hsu YH,Lee KY,Jiang FW,Kuo LW, Chen YJ, Han CL. Chemotherapy Immunophenoprofiles in Non-Small-Cell Lung Cancer by Personalized Membrane Proteomics. . Proteomics Clinical Applications .2018

48. 2018 Lee KY,Feng PH,Chuang HC,Wu SM,Liu WT,Chen KY, Liu CY, Ho SC. Trace Elements in Pleural Effusion Correlates with Smokers with Lung Cancer. . Biological Trace Element Research .2018

49. 2015 Lee KY,Feng PH,Ho SC,Chuang KJ,Chen TT,Su CL, Liu WT, Chuang HC.. Inter-alpha-trypsin inhibitor heavy chain 4: a novel biomarker for environmental exposure to particulate air pollution in patients with chronic obstructive pulmonary disease. . Int J Chron Obstruct Pulmon Dis .2015 ;(10):831-841

50. 2015 Feng PH,Huang YL,Chuang KJ,Chen KY,Lee KY,Ho SC, Bien MY, Yang YL, Chuang HC. Dysfunction of methionine sulfoxide reductases to repair damaged proteins by nickel nanoparticles . Chemico-Biological Interactions .2015 ;(236):82-89

51. 2015 Chuang HC,Su CL,Liu HC,Feng PH,Lee KY,Chuang KJ, Lee CN, Bien MY.. Cigarette smoke is a risk factor for severity and treatment outcome in patients with culture-positive tuberculosis . Therapeutics and Clinical Risk Management .2015 ;(11):1539-1544

52. 2015 Lee KY,Chuang HC,Chen TT,Liu WT,Su CL,Feng PH, Chiang LL, Bien MY, Ho SC. Proteoglycan 4 is a diagnostic biomarker for COPD. . Int J Chron Obstruct Pulmon Dis .2015 ;(10):1999-2007

53. 2015 Chuang HC,Ho KF,Cao JJ,Chuang KJ,Ho SS,Feng PH, Tian L, Lee CH8, Han YM9, Lee CN10, Cheng TJ. Effects of non-protein-type amino acids of fine particulate matter on E-cadherin and inflammatory responses in mice. . Toxicol Lett. .2015 ;(237):174-180

54. 2014 Feng PH,Yu CT,Wu CY,Lee MJ,Lee WH,Wang LS, Lin SM, Fu JF, Lee KY, Yen TH. Tumor-associated macrophages in stage IIIA pN2 non-small cell lung cancer after neoadjuvant chemotherapy and surgery . Am J Transl Res .2014 ;(6):593-603

55. 2013 Weng CM,Chen BC,Wang CH,FengPH,Lee MJ,Huang CD, Kuo HP, Lin CH.. The endothelin A receptor mediates fibrocyte differentiation in chronic obstructive asthma. The involvement of connective tissue growth factor. . Am J Respir Crit Care Med .2013 ;(188):298-308

56. 2012 Feng PH,Lee KY,Chang YL,Chan YF,Kuo LW,Lin TY, Chung FT, Kuo CS, Yu CT, Lin SM, Wang CH, Chou CL, Huang CD, Kuo HP. CD14+S100A9+ Monocytic Myeloid-derived Suppressor Cells and Their Clinical Relevance in Non-Small Cell Lung Cancer . American Journal of Respiratory and Critical Care Medicine .2012 ;(186):1025-1036

研究計畫

計畫名稱
112 TIGIT 在調節免疫拮抗點抑制劑抗藥性的角色(3/3)
補助單位
國家科學及技術委員會

計畫名稱
111 TIGIT 在調節免疫拮抗點抑制劑抗藥性的角色(2/3)
補助單位
國家科學及技術委員會

計畫名稱
110 TIGIT 在調節免疫拮抗點抑制劑抗藥性的角色(1/3)
補助單位
科技部

計畫名稱
109 肺癌病人 T 細胞耗竭的調控機制
補助單位
科技部

計畫名稱
108 探討CD155/TIGIT在類骨髓衍生抑制細胞/腫瘤衍生巨噬細胞誘導自然殺手細胞失調的機轉- 研究肺癌病人免疫檢查點阻斷藥物抗藥性機轉
補助單位
科技部

計畫名稱
106 腫瘤微環境誘發表皮生長因子受器-酪氨酸酶拮抗劑抗藥性之機轉
補助單位
科技部

計畫名稱
104 以蛋白體分析探討愛寧達在非小細胞肺癌中引發之分子機制
補助單位
行政院衛生署雙和醫院(委託臺北醫學大學興建經營)

計畫名稱
104 探討化學治療藥物對於誘導發炎細胞至肺癌病人腫瘤微環境的影響與機轉
補助單位
科技部

計畫名稱
103 腫瘤相關巨噬細胞在誘發產生表皮生長因子受器酪胺酸酉每抑制劑的抗藥性的角色
補助單位
科技部

計畫名稱
103 TMU103-AE1-B31
補助單位
臺北醫學大學

計畫名稱
103 (103)新聘教師專題研究計劃-馮博皓教師
補助單位
臺北醫學大學

計畫名稱
102 在非小細胞肺癌病人其免疫系統之變化及免疫原性細胞死亡與治療預後的關係
補助單位
行政院國家科學委員會

計畫名稱
102 在非小細胞肺癌病人其免疫系統之變化及免疫原性細胞死亡與治療預後的關係
補助單位
科技部