| 1. |
2024
Huang WC,Shu LH,Kuo YJ,Lai KS,Hsia CW,Yen TL, Hsia CH, Jayakumar T, Yang CH, Sheu JR.
Eugenol Suppresses Platelet Activation and Mitigates Pulmonary Thromboembolism in Humans and Murine Models
. International Journal of Molecular Sciences
.2024
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| 2. |
2023
Attenuation of indoxyl sulfate-induced cell damage by cinchonidine-a Cinchona alkaloid-through the downregulation of p53 signaling pathway by promoting MDM2 cytoplasmic-nuclear shuttling in endothelial cells.
. life sciences
.2023
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| 3. |
2023
Kakoty V,Kc S,Yang CH,Dubey SK,Taliyan R.
Exploring the Epigenetic Regulated Modulation of Fibroblast Growth Factor 21 Involvement in High-Fat Diet Associated Parkinson's Disease in Rats
. ACS Chem Neurosci
.2023
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| 4. |
2023
Hsieh CT,Yen TL,Chen YH,Jan JS,Teng RD,Yang CH, Sun JM..
Aging-Associated Thyroid Dysfunction Contributes to Oxidative Stress and Worsened Functional Outcomes Following Traumatic Brain Injury
. Antioxidants (Basel)
.2023
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| 5. |
2023
Kakoty V,Kc S,Kumari S,Yang CH,Dubey SK,Sahebkar A, Kesharwani P, Taliyan R.
Brain insulin resistance linked Alzheimer's and Parkinson's disease pathology: An undying implication of epigenetic and autophagy modulation
. Inflammopharmacology
.2023
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| 6. |
2023
Linh TTD,Ho DKN,Nguyen NN,Hu CJ,Yang CH,Wu D..
Global prevalence of post-COVID-19 sleep disturbances in adults at different follow-up time points: A systematic review and meta-analysis
. Sleep Med Rev
.2023
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| 7. |
2023
Overexpressing glyoxalase 1 attenuates acute hyperglycemia-exacerbated neurological deficits of ischemic stroke in mice
. Transl Res
.2023
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| 8. |
2022
Advances in Antibody-Based Therapeutics for Cerebral Ischemia.
. Pharmaceutics.
.2022
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| 9. |
2022
Kakoty V,C SK,Yang CH,Kumari S,Dubey SK,Taliyan R.
Neuroprotective Effect of Lentivirus-Mediated FGF21 Gene Delivery in Experimental Alzheimer's Disease is Augmented when Concerted with Rapamycin.
. Mol Neurobiol.
.2022
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| 10. |
2021
Chiu CW,Yang CH,Tsai JH,Hsieh CY,Huang SY.
Platonin, a Cyanine Photosensitizing Dye, Ameliorates Inflammatory Responses in Vascular Smooth Muscle Cells by Modulating Inflammatory Transcription Factors.
. Appl. Sci.
.2021
;(11(3))
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| 11. |
2021
Lee Tzu Yin,Lu Wan Jung,Changou Chun A.,Hsiung Yuan Chin,Trang Nguyen T.T.,Lee Cheng Yang,Chang Tzu Hao,Jayakumar Thanasekaran,Hsieh Cheng Ying,Yang Chih Hao,Chang Chao Chien,Chen Ray Jade,Sheu Joen Rong,Lin Kuan Hung,Lee Tzu Yin,Lu Wan Jung,Changou Chun A.,Hsiung Yuan Chin,Trang Nguyen T.T.,Lee Cheng Yang,Chang Tzu Hao,Jayakumar Thanasekaran,Hsieh Cheng Ying,Yang Chih Hao,Chang Chao Chien,Chen Ray Jade,Sheu Joen Rong,Lin Kuan Hung.
Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism
. Autophagy
.2021
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| 12. |
2021
Huang Wei Chieh,Liu Ju Chi,Hsia Chih Wei,Fong Tsorng Harn,Hsia Chih Hsuan,Tran Oanh Thi,Velusamy Marappan,Yang Chih Hao,Sheu Joen Rong,Huang Wei Chieh,Liu Ju Chi,Hsia Chih Wei,Fong Tsorng Harn,Hsia Chih Hsuan,Tran Oanh Thi,Velusamy Marappan,Yang Chih Hao,Sheu Joen Rong.
Pterostilbene, a Dimethylether Analogue of Resveratrol, Possesses High Potency in the Prevention of Platelet Activation in Humans and the Reduction of Vascular Thrombosis in Mice
. Journal of Agricultural and Food Chemistry
.2021
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| 13. |
2021
Solid Lipid Nanoparticles (SLNs): An Advanced Drug Delivery System Targeting Brain through BBB
. Pharmaceutics
.2021
;(13):1183
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| 14. |
2020
Yang CH,Di Antonio A,Kirschen GW,Varma P,Hsieh J,Ge S.
Circuit Integration Initiation of New Hippocampal Neurons in the Adult Brain.
. Cell Rep.
.2020
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| 15. |
2020
Kakoty V,K C S,Tang RD,Yang CH,Dubey SK,Taliyan R.
Fibroblast growth factor 21 and autophagy: A complex interplay in Parkinson disease
. Biomed Pharmacother.
.2020
;(127)
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| 16. |
2020
Lin CT,Lecca D,Yang LY,Luo W,Scerba MT,Tweedie D, Huang PS, Jung YJ, Kim DS, Yang CH, Hoffer BJ, Wang JY, Greig NH.
3,6'-dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation.
. Elife.
.2020
;(9)
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| 17. |
2020
Hsia CW,Yang CH,Sheu JR,Hsia CH,Tsai CL,Huang WC, Chen TY, Thanasekara Jayakumar T, Bhavan PS, Chang Y.
Reduction of NF-κB Signals in Platelets and Prolongation of Platelet Plug Formation against High Shear Flow in Whole Blood on Human Subject by Columbianadin.
. Appl. Sci.
.2020
;(10 (20))
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| 18. |
2019
Jan JS,Yang CH,Wang MH,Lin FL,Yen JL,Hsieh I, Khotimchenko M, Lee TH, Hsiao G.
Hirsutanol A Attenuates Lipopolysaccharide-Mediated Matrix Metalloproteinase 9 Expression and Cytokines Production and Improves Endotoxemia-Induced Acute Sickness Behavior and Acute Lung Injury.
. Mar Drugs.
.2019
|
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| 19. |
2019
Sheu JR,Hsieh CY,Jayakumar T,Lin GY,Lee HN,Huang SW, Yang CH.
HDAC6 dysfunction contributes to impaired maturation of adult neurogenesis in vivo: vital role on functional recovery after ischemic stroke.
. Journal of Biomedical Science
.2019
;(26):1-17
|
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| 20. |
2019
Sheu JR,Hsieh CY,Jayakumar T,Tseng MF,Lee HN,Huang SW, Manubolu M, Yang CH.
A Critical Period for the Development of Schizophrenia-Like Pathology by Aberrant Postnatal Neurogenesis.
. Frontiers in Neuroscience
.2019
|
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| 21. |
2019
Hsieh CY,Sheu JR,Yang CH,Chen WL,Tsai JH,Chung CL.
Thrombin Upregulates PAI-1 and Mesothelial-Mesenchymal Transition Through PAR-1 and Contributes to Tuberculous Pleural Fibrosis.
. Int J Mol Sci.
.2019
|
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| 22. |
2018
Sheu JR,Chen ZC,Hsu MJ,Wang SH,Jung KW,Wu WF, Pan SH, Teng RD, Yang CH, Hsieh CY.
CME-1, a novel polysaccharide, suppresses iNOS expression in lipopolysaccharide-stimulated macrophages through ceramide-initiated protein phosphatase 2A activation.
. Journal of Cellular and Molecular Medicine
.2018
;(22):999-1013
|
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| 23. |
2018
Jayakumar T,Liu CH,Wu GY,Lee TY,Manubolu M,Hsieh CY, Yang CH, Sheu JR.
Hinokitiol Inhibits Migration of A549 Lung Cancer Cells via Suppression of MMPs and Induction of Antioxidant Enzymes and Apoptosis.
. International Journal of Molecular Sciences
.2018
;(19)
|
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| 24. |
2018
Yen TL,Chang CC,Chung CL,Ko WC,Yang CH,Hsieh CY.
Neuroprotective Effects of Platonin, a Therapeutic Immunomodulating Medicine, on Traumatic Brain Injury in Mice after Controlled Cortical Impact.
. International Journal of Molecular Sciences
.2018
;(19)
|
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| 25. |
2018
Yang CH,Hsia CW,Jayakumar T,Sheu JR,Hsia CH,Khamrang T, Chen YJ, Manubolu M, Chang Y.
Structure⁻Activity Relationship Study of Newly Synthesized Iridium-III Complexes as Potential Series for Treating Thrombotic Diseases.
. International Journal of Molecular Sciences
.2018
;(19)
|
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| 26. |
2018
Shyu KG,Velusamy M,Hsia CW,Yang CH,Hsia CH,Chou DS, Jayakumar T, Sheu JR, Li JY.
Novel iridium (III)‑derived organometallic compound for the inhibition of human platelet activation.
. International Journal of Molecular Medicine
.2018
;(41):2589-2600
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| 27. |
2017
Yang CH,Yen TL,Hsu CY,Thomas PA,Sheu JR,Jayakumar T.
Multi-targeting andrographolide, a novel NF-κB inhibitor, as a potential therapeutic agent for stroke.
. International Journal of Molecular Sciences
.2017
;(18)
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| 28. |
2017
Sheu JR,Chen ZC,Jayakumar T,Chou DS,Yen TL,Lee HN, Pan SH, Hsia CH, Yang CH, and Hsieh CY.
A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice
. Scientific reports
.2017
;(7)
|
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| 29. |
2016
Jayakumar T,Yang CH,Geraldine P,Yen TL,Sheu JR.
The pharmacodynamics of antiplatelet compounds in thrombosis treatment.
. Expert Opinion on Drug Metabolism & Toxicology
.2016
;(12):615-632
|
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| 30. |
2015
Ma D,Yoon SI,Yang CH,Marcy G,Zhao N,Leong WY, Ganapathy V, Han J, Van Dongen AM, Hsu KS, Ming GL, Augustine GJ, Goh EL.
Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital
. Neurotherapeutics
.2015
;(12):477-490
|
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| 31. |
2015
Yang PS,Lin PY,Chang CC,Yu MC,Yen TL,Lan CC, Jayakumar T, Yang CH..
Antrodia camphorata Potentiates Neuroprotection against Cerebral Ischemia in Rats via Downregulation of iNOS/HO-1/Bax and Activated Caspase-3 and Inhibition of Hydroxyl Radical Formation.
. Evidence-Based Complementary and Alternative Medicine
.2015
;(2015):1-8
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| 32. |
2015
Yen TL,Chen RJ,Jayakumar T,Lu WJ,Hsieh CY,Hsu MJ, Yang CH, Chang CC, Lin YK, Lin KH, Sheu JR.
Andrographolide stimulates p38 mitogen-activated protein kinase-nuclear factor erythroid-2-related factor 2-heme oxygenase 1 signaling in primary cerebral endothelial cells for definite protection against ischemic stroke in rats.
. Translational Research
.2015
|
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| 33. |
2012
Huang YF,Yang CH,Huang CC,Hsu KS.
Vascular endothelial growth factor-dependent spinogenesis underlies antidepressant-like effects of enriched environment
. The Journal of Biological Chemistry
.2012
;(287):40938-40955
|
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| 34. |
2012
Yang CH,Huang CC,Hsu KS.
A critical role for protein tyrosine phosphatase nonreceptor type 5 in determining individual susceptibility to develop stress-related cognitive and morphological changes
. The Journal of Neuroscience
.2012
;(32):7550-7562
|
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| 35. |
2011
Yang CH,Huang CC,Hsu KS.
Generalization of fear inhibition by disrupting hippocampal protein synthesis-dependent reconsolidation process
. Neuropsychopharmacology
.2011
;(36):1992-2008
|
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| 36. |
2010
Huang YF,Yang CH,Huang CC,Tai MH,Hsu KS.
Pharmacological and genetic accumulation of hypoxia-inducible factor-1alpha enhances excitatory synaptic transmission in hippocampal neurons through the production of vascular endothelial growth factor
. The Journal of Neuroscience
.2010
;(30):6080-6093
|
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| 37. |
2010
Chen CC,Yang CH,Huang CC,Hsu KS.
Acute stress impairs hippocampal mossy fiber-CA3 long-term potentiation by enhancing cAMP-specific phosphodiesterase 4 activity
. Neuropsychopharmacology
.2010
;(35):1605-1617
|
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| 38. |
2009
Chang YJ,Yang CH,Liang YC,Yeh CM,Huang CC,Hsu KS.
Estrogen modulates sexually dimorphic contextual fear extinction in rats through estrogen receptor beta
. Hippocampus
.2009
;(19):1142-1150
|
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| 39. |
2008
Yang CH,Huang CC,Hsu KS.
Differential roles of basolateral and central amygdala on the effects of uncontrollable stress on hippocampal synaptic plasticity
. Hippocampus
.2008
;(18):548-563
|
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| 40. |
2008
Yang PC,Yang CH,Huang CC,Hsu KS.
Phosphatidylinositol 3-kinase activation is required for stress protocol-induced modification of hippocampal synaptic plasticity
. The Journal of Biological Chemistry
.2008
;(283):2631-2643
|
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| 41. |
2007
Duan X,Chang JH,Ge S,Faulkner RL,Kim JY,Kitabatake Y, Liu XB, Yang CH, Jordan JD, Ma DK, Liu CY, Ganesan S, Cheng HJ, Ming GL, Lu B, Song H.
Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain
. Cell
.2007
;(130):1146-1158
|
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| 42. |
2007
Ge S,Yang CH,Hsu KS,Ming GL,Song H.
A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain
. Neuron
.2007
;(54):559-566
|
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| 43. |
2006
Yang CH,Huang CC,Hsu KS.
Novelty exploration elicits a reversal of acute stress-induced modulation of hippocampal synaptic plasticity in the rat
. The Journal of Physiology
.2006
;(577):601-615
|
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| 44. |
2005
Huang CC,Yang CH,Hsu KS.
Do stress and long-term potentiation share the same molecular mechanisms?
. Molecular Neurobiology
.2005
;(32):223-235
|
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| 45. |
2005
Huang CC,Chou PH,Yang CH,Hsu KS.
Neonatal isolation accelerates the developmental switch in the signalling cascades for long-term potentiation induction
. The Journal of Physiology
.2005
;(569):789-799
|
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| 46. |
2005
Yang CH,Huang CC,Hsu KS.
Behavioral stress enhances hippocampal CA1 long-term depression through the blockade of the glutamate uptake
. The Journal of Neuroscience
.2005
;(25):4288-4293
|
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| 47. |
2004
Yang CH,Huang CC,Hsu KS.
Behavioral stress modifies hippocampal synaptic plasticity through corticosterone-induced sustained extracellular signal-regulated kinase/mitogen-activated protein kinase activation
. The Journal of Neuroscience
.2004
;(24):11029-11034
|
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