謝燿宇(Hsieh, Yao-Yu) 助理教授

Email
d621101002@tmu.edu.tw
現   職
內科學科 助理教授

學經歷

學 歷

畢業學校與學位[修業時間]
國立陽明大學醫學系 學士
1997/09~2004/06

本校學術經歷

任職單位與職稱[起迄時間]
內科學科助理教授
2019/08/01~
內科學科講師
2014/08/01~2019/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
陽明大學醫學系兼任講師
2011/09~2012/07

專長與研究領域

學門領域
學術專長

論文著作

清冊下載


1. 2024 Yi-Che Huang,Fei-Yuan Hsiao,Shang-Ting Guan,Ming Yao,Chia-Jen Liu,Tzu-Ting Chen, Tung-Liang Lin, Yi-Chang Liu, Tsai-Yun Chen, Ying-Chung Hong, Ming-Chun Ma, Tran-Der Tan, Chuan-Cheng Wang, Yi-Ying Wu, Po-Wei Liao, Yi-Feng Wu, Yi-Yang Chen, Yuan-Bin Yu, Yao-Yu Hsieh, Ming-Yang Lee, Jia-Hau Liu, Shu-Wen Lin, Bor-Sheng Ko. Share Ten-year epidemiology and risk factors of cytomegalovirus infection in hematopoietic stem cell transplantation patients in Taiwan. . J Microbiol Immunol Infect .2024

2. 2024 Chia-Hwa Lee,Kai-Wen Hsu,Yao-Yu Hsieh,Wei-Ting Li,Yuqing Long,Chun-Yu Lin. Unveiling IL6R and MYC as Targeting Biomarkers in Imatinib-Resistant Chronic Myeloid Leukemia through Advanced Non-Invasive Apoptosis Detection Sensor Version 2 Detection . Cells .2024

3. 2024 Yao-Yu Hsieh,Jia-Ling Du,Pei-Ming Yang. Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer and overcoming drug resistance . Mol Oncol .2024

4. 2023 Khaa Hoo Ong,Yao-Yu Hsieh,Ding-Ping Sun,Steven Kuan-Hua Huang,Yu-Feng Tian,Chia-Ling Chou. Underexpression of Carbamoyl Phosphate Synthetase I as Independent Unfavorable Prognostic Factor in Intrahepatic Cholangiocarcinoma: A Potential Theranostic Biomarker . Diagnostics (Basel) .2023

5. 2023 Tom Wei-Wu Chen,Ming-Shen Dai,Ling-Ming Tseng,Shin-Cheh Chen,Tsu-Yi Chao,Ta-Chung Chao, Yuan-Ching Chang, Chang-Fang Chiu, Chien-Ting Liu, Ching-Hung Lin, Chun-Yu Liu, Ya-Fang Chen, Dwan-Ying Chang, Jyh-Cherng Yu, Kun-Ming Rau, Yao-Yu Hsieh, Shih-Che Shen, Shu-Min Huang, Ann-Lii Cheng, Yen-Shen Lu. Whole-Brain Radiotherapy Alone vs Preceded by Bevacizumab, Etoposide, and Cisplatin for Untreated Brain Metastases From Breast Cancer: A Randomized Clinical Trial. . JAMA oncology .2023

6. 2023 Ong KH,Hsieh YY,Lai HY,Sun DP,Chen TJ,Huang SK. LAMC2 is a potential prognostic biomarker for cholangiocarcinoma . Oncol Lett .2023

7. 2023 Chang YT,Chen CC,Chang SC,Chang YY,Lin BW,Chen HH, Hsieh YY, Hsu HC, Hsieh MC, Kuan FC, Wu CC, Lu WC, Su YL, Liang YH, Chen JB, Huang SY, Huang CW, Wang JY.. Efficacy and Safety of a Parenteral Nutrition Program for Patients with RAS Wild-Type Metastatic Colorectal Cancer Administered First-Line Cetuximab Plus Chemotherapy: A Propensity Score Matching Study . Nutrients .2023

8. 2023 Chen CC,Chang SC,Chang YY,Lin BW,Chen HH,Hsieh YY, Hsu HC, Hsieh MC, Ke TW, Kuan FC, Wu CC, Lu WC, Su YL, Liang YH, Chen JB, Huang HY, Tsai HL, Wang JY.. Survival benefit of metastasectomy in first-line cetuximab therapy in patients with RAS wild-type metastatic colorectal cancer: a nationwide registry. . American Journal of cancer research .2023

9. 2022 Hsieh YY,Chen YM,Wei PL,Yang PM. Repurposing of ingenol mebutate for treating human colorectal cancer by targeting S100 calcium-binding protein A4 (S100A4) . Toxicology and Applied Pharmacology .2022

10. 2022 Hsieh YY. Long Non-Coding RNA MIR31HG Promotes the Transforming Growth Factor β-Induced Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma Cells . Int J Mol Sci .2022 ;(23):6559

11. 2021 Cheng-Chih Tsai,Yung-Cheng Su,Oluwaseun Adebayo Bamodu,Bo-Jung Chen,Wen-Chiuan Tsai,Wei-Hong Cheng, Chii-Hong Lee, Shu-Min Hsieh, Mei-Ling Liu, Chia-Lang Fang, Huan-Tze Lin, Chi-Long Chen, Chi-Tai Yeh, Wei-Hwa Lee, Ching-Liang Ho, Shiue-Wei Lai, Huey-En Tzeng, Yao-Yu Hsieh, Chia-Lun Chang, Yu-Mei Zheng, Hui-Wen Liu, Yun Yen, Jacqueline Whang-Peng, Tsu-Yi Chao. High-Grade B-Cell Lymphoma (HGBL) with MYC and BCL2 and/or BCL6 Rearrangements Is Predominantly BCL6-Rearranged and BCL6-Expressing in Taiwan . Cancers (Basel). .2021 ;(13):1620

12. 2021 Taiwan Society of Colon and Rectal Surgeons Consensus on mCRC Treatment . frontiers in oncology .2021 ;(11):764912

13. 2021 EBV-positive low-grade follicular lymphoma transforming to EBV-negative high-grade B-cell lymphoma with MYC and BCL2 rearrangements . Pathology .2021 ;(54):634-636

14. 2020 Pei-Ming Yang,Yao-Yu Hsieh,Jia-Ling Du,Shih-Chieh Yen,Chien-Fu Hung . Sequential Interferon β-Cisplatin Treatment Enhances the Surface Exposure of Calreticulin in Cancer Cells via an Interferon Regulatory Factor 1-Dependent Manner . Biomolecules .2020 ;(10):463

15. 2020 Li-Wei Liu,Yao-Yu Hsieh,Pei-Ming Yang. Bioinformatics Data Mining Repurposes the JAK2 (Janus Kinase 2) Inhibitor Fedratinib for Treating Pancreatic Ductal Adenocarcinoma by Reversing the KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog)-Driven Gene Signature . J Pers Med. .2020 ;(10):130

16. 2020 Hsieh YY,Fang WT,Lo YW,Chen YH,Chien LN. Comparing the effectiveness of different EGFR-TKIs in patients with EGFR mutant non-small-cell lung cancer: A retrospective cohort study in Taiwan. . Int J Cancer .2020 ;(147):1107-1116

17. 2020 Chen SH,Hsieh YY,Tzeng HE,Lin CY,Hsu KW,Chiang YS, Lin SM, Su MJ, Hsieh WS, Lee CH. ABL Genomic Editing Sufficiently Abolishes Oncogenesis of Human Chronic Myeloid Leukemia Cells In Vitro and In Vivo. . Cancers (Basel) .2020 ;(12):1399-1399

18. 2019 Hsieh YY,Liu TP,Chou CJ,Chen HY,Lee KH,Yang PM. Integration of Bioinformatics Resources Reveals the Therapeutic Benefits of Gemcitabine and Cell Cycle Intervention in SMAD4-Deleted Pancreatic Ductal Adenocarcinoma. . Genes (Basel). .2019 ;(10):766-766

19. 2019 Hsieh YY,Liu TP,Yang PM. In silico repurposing the Rac1 inhibitor NSC23766 for treating PTTG1-high expressing clear cell renal carcinoma. . Pathol Res Pract .2019

20. 2019 Chen JC,Hsieh YY,Lo HL,Li A,Chou CJ,Yang PM. In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells. . Biomolecules .2019 ;(9):pii: E467

21. 2019 Yao-Yu Hsieh,Tsang-Pai Liu,Chia-Jung Chou,Hsin-Yi Chen,Kuen-Haur Lee,Pei-Ming Yang. Integration of Bioinformatics Resources Reveals the Therapeutic Benefits of Gemcitabine and Cell Cycle Intervention in SMAD4-Deleted Pancreatic Ductal Adenocarcinoma. . Genes(Basel) .2019 ;(10):pii: E766

22. 2019 Shu-Huey Chen,Jyh-Ming Chow,Yao-Yu Hsieh,Chun-Yu Lin,Kai-Wen Hsu,Wen-Shyang Hsieh, Wei-Ming Chi, Beished M Shabangu , Chia-Hwa Lee. HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells . Int J Mol Sci. .2019 ;(20):2271-2271

23. 2018 Liu TP,Hsieh YY,Chou CJ,Yang PM. Systematic polypharmacology and drug repurposing via an integrated L1000-based Connectivity Map database mining. . Royal Society Open Science .2018 ;(5):181321

24. 2016 Hsieh YY,Huang TC,Lo HL,Jhan JY,Chen ST,Yang PM. Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: identification of functional disparities between azacytidine and decitabine . Oncotarget .2016 ;(7):27363-27378

25. 2016 Hsieh Yy,Lo HL,Yang PM. EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells . American Journal of Cancer Research .2016

26. 2015 Hsieh YY,Yang ST,Li WH,Hu CJ,Wang LS. Primary leptomeningeal melanoma mimicking meningitis – A case report and literature review . Journal of clinical oncology .2015 ;(33):e57-e61

27. 2012 Hsieh YY,Tzeng CH,Chen MH,Chen PM,Wang WS. Epidermal growth factor receptor R521K polymorphism shows favorable outcomes in KRAS wild-type colorectal cancer patients treated with cetuximab-based chemotherapy . Cancer Science .2012 ;(103):791-796

28. 2011 Hsieh YY,Chang MH,Chen MH,Chu PY,Tzeng Ch,Chang SY, Chen PM, Yang MH. Pretreatment risk stratification for non-metastatic head and neck squamous cell carcinoma in a high-prevalence area. . Journal of Chinese Medical Association .2011 ;(74):487-492

29. 2011 Hsieh YY,Yen CC,Yeh CN,Tzeng CY,Liu JH,Lee HJ, Teng HW, Tzeng CH, Chiou TJ, Chao TC. Effective salvage therapy of imatinib-resistant gastrointestinal stromal tumor with combination of imatinib and pegylated liposomal doxorubicin. . Journal of Chinese Medical Association .2011 ;(74):272-274

30. 2011 Teng HW,Wang WH,Chen WM,Chao TC,Hsieh YY,Hsih CH, Tzeng CH, Chen PC, Yen CC. Prevalence and prognostic influence of genomic changes of EGFR pathway markers in synovial sarcoma. . Journal of surgical oncology .2011 ;(103):773-781

31. 2011 Hsieh YY,Hong YC,Hsiao LT,Yu YB,Liu JH,Gau JP, Lin HN, Hsu YN, Chiou TJ, Chen PM, Tzeng CH, Liu CY. Effect of allogeneic hematopoietic stem cell transplantation from matched siblings or unrelated donors during the first complete remission in patients with cytogenetically normal acute myeloid leukemia. . European Journal of Haematology .2011 ;(86):237-245

32. 2011 Teng CJ,Hsieh YY,Chen KW,Chao TC,Tzeng CH,Wang WS. Sudden-onset pancytopenia with intracranial hemorrhage after oxaliplatin treatment: a case report and literature review. . Japanese Journal of clinical oncology .2011 ;(41):125-129

33. 2010 Chang PM,Hsieh YY,Chen MH,Tzeng CH,Chu PY,Chang SY, Chen PM, Yang MH. Cetuximab-based therapy in recurrent/metastatic head and neck squamous cell carcinoma: experience from an area in which betel nut chewing is popular. . Journal of Chinese Medical Association .2010 ;(73):292-299

34. 2010 Liu JH,Hsieh YY,Chen WS,Hsu YN,Chau GY,Teng HW, King KL, Lin TC, Tzeng CH, Lin JK. Adjuvant oxaliplatin- or irinotecan-containing chemotherapy improves overall survival following resection of metachronous colorectal liver metastases. . Int J Colorectal Dis. .2010 ;(25):1243-1249

研究計畫

計畫名稱
113 針對BTK/BCL2L11 axis的雙重標的對順鉑頑固型耐藥食道癌細胞的意義
補助單位
國家科學及技術委員會

計畫名稱
113 靶向MIR31HG/LncHIFCAR 相關分子網絡在胰腺癌轉移和腫瘤微環境的研究-靶向致癌性非編碼核醣核酸 MIR31HG/miR-31分子調控網絡以增進胰臟癌治療效果(2/3)
補助單位
國家科學及技術委員會

計畫名稱
112 布鲁頓酪氨酸激酶(Bruton's tyrosine kinase , BTK)對頑固型耐藥食道癌細胞鐵死亡敏感性之機制研究
補助單位
國家科學及技術委員會

計畫名稱
112 靶向MIR31HG/LncHIFCAR 相關分子網絡在胰腺癌轉移和腫瘤微環境的研究-靶向致癌性非編碼核醣核酸 MIR31HG/miR-31分子調控網絡以增進胰臟癌治療效果(1/3)
補助單位
國家科學及技術委員會

計畫名稱
107 透過老藥新用發現一個M5毒蕈鹼乙酰膽鹼受體之正向異位性調節劑可作為微管標靶藥物,及其應用於治療胰臟管腺癌
補助單位
科技部