| 1. |
2024
Tran HL,Lai KH,Chang HS,Chen YS,Wang HC,Yang SS, Chang HW, Hsu CM, Hsiao HH, Yen CH.
Indigofera suffruticosa aerial parts extract induce G2/M arrest and ATR/CHK1 pathway in Jurkat cells.
. BMC Complementary Medicine and Therapies
.2024
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| 2. |
2024
Cheng TY,Yang CJ,Chen PJ,Chen YL,Peng BR,Kung TA, Wen ZH, Lai KH, Chung HM.
Capnesterones A and B, new steroids isolated from the soft coral Capnella imbricata.
. Phytochemistry Letters
.2024
|
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| 3. |
2024
El-Deeb EM,Elsayed HE,Ateya HB,Taha HS,Elgindi MR,Abouelenein D, Caprioli G, Lai KH*, Mustafa AM, Moharram FA.
Phenolic profiling and bioactivity assessment of in vitro propagated Psidium cattleianum Sabine: A promising study.
. Heliyon
.2024
|
|
| 4. |
2024
Le HG,Chen YS,Cheng TP,Tsai YF,Chen PJ,Cheng WC, El-Shazly M, Chang YC, Hwang TL, Lai KH*.
Exploring anti-inflammatory non-essential oil metabolites in Mentha canadensis: Insights into neutrophil extracellular trap inhibition for functional health promotion.
. Journal of Functional Foods
.2024
|
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| 5. |
2023
Nguyen NBA ,Chen LY,Chen PJ,El-Shazly M,Hwang TL,Su JH, Su CH, Yen PT, Peng BR, Lai KH.
MS/MS Molecular Networking Unveils the Chemical Diversity of Biscembra-noid Derivatives, Neutrophilic Inflammatory Mediators from the Cultured Soft Coral Sarcophyton trocheliophorum
. International Journal of Molecular Sciences
.2023
|
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| 6. |
2023
Wu I. Ting,Fan Yu Chen,Lin Guan Zhou,Wang Yi Lin,Hwang Tsong Long,Lai Kuei Hung,Chung Hsu Ming,Wu I. Ting,Fan Yu Chen,Lin Guan Zhou,Wang Yi Lin,Hwang Tsong Long,Lai Kuei Hung,Chung Hsu Ming.
A new capnellene skeleton from the octocoral Capnella imbricata (Quoy & Gaimard, 1833)
. Journal of Molecular Structure
.2023
;(1271)
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| 7. |
2023
Chen Yu Li,Chen Chun Yu,Lai Kuei Hung,Chang Yu Chia,Hwang Tsong Long,Chen Yu Li,Chen Chun Yu,Lai Kuei Hung,Chang Yu Chia,Hwang Tsong Long.
Anti-inflammatory and antiviral activities of flavone C-glycosides of Lophatherum gracile for COVID-19
. Journal of Functional Foods
.2023
;(101)
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| 8. |
2023
Mady MS*,Ibrahim RR,Elsayed EK,El-Shazly M,Chen LY,Lai KH*, El-Shaarawy FS, Moharram FA.
UHPLC-MS profiles and antidiarrheal activity of Quercus coccinea münchh. and Quercus robur L. employing in vivo technique
. Frontiers in Pharmacology
.2023
;(14):1120146
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| 9. |
2023
Te-An Kung,Lo-Yun Chen,Chia-Ying Li,Bo-Rong Peng,Tsong-Long Hwang, Ping-Jyun Sung, Kuei-Hung Lai, Hsu-Ming Chung.
Anti-inflammatory cembrane-based diterpenoids isolated from the octocoral Sinularia querciformis
. Phytochemistry Letters
.2023
;(55):12-16
|
|
| 10. |
2023
Wang LS,Chen PJ,Cheng WC,Chang YC,El-Shazly M,Chen LY, Peng BR, Su CH, Yen PT, Hwang TL*, Lai KH*.
Chemometric-guided chemical marker selection: A case study of the heat-clearing herb Scrophularia ningpoensis
. Frontiers in Plant Science
.2023
;(14):1153710
|
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| 11. |
2023
El-Sayed EK,Ibrahim RR,Ahmed AA,Khattab MA,Chen LY,Lai KH*, ElShaarawy FS, Tawfik NF, Moharram FA.
Quercus coccinea Münchh. leaves polyphenols: Appraisal acute lung injury induced by lipopolysaccharide in mice
. Biomecine & Pharmacotherapy
.2023
|
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| 12. |
2023
Lai KH,Fan YC,Peng BR,Wen ZH,Chung HM.
Capnellenes from Capnella imbricata: Deciphering their anti-inflammatory-associated chemical features
. Pharmaceuticals
.2023
;(16):916
|
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| 13. |
2023
Peng BR,Zheng LG,Chen LY,El-Shazly M,Hwang TL,Su JH, Lee MH, Lai KH, Sung PJ.
Nor-24-homoscalaranes, neutrophilic inflammatory mediators from the marine sponge Lendenfeldia sp.
. Pharmaceuticals
.2023
;(16):1258
|
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| 14. |
2023
Hung CL,Huang LC,Shih KY,Lai KH,Peng BR,Hwang TL, Chien SY, Li CY, Chung HM.
A new sterol from the Formosan soft coral Lobophytum durum
. Journal of Molecular Structure
.2023
;(1296):136790
|
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| 15. |
2023
Nguyen NBA,El-Shazly M,Chen PJ,Peng BR,Chen LY,Hwang TL, Lai KH.
Unlocking the potential of octocoral-derived secondary metabolites against neutrophilic inflammatory response
. Marine Drugs
.2023
;(21):456
|
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| 16. |
2023
Peng BR,Nguyen NBA,Chen LY,El-Shazly M,Hwang TL,Su JH, Lai KH.
Unprecedented anti-inflammatory biscembranpoids with 3-hydroperoxy-3- methylcyclohex-1-ene moiety isolated from aquaculture Sarcophyton trocheliophorum
. Aquaculture Reports
.2023
|
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| 17. |
2022
Li Zong You,Li Chia Ying,Lai Kuei Hung,Liao Mei Yi,Wang Wei Hsien,Chung Hsu Ming,Li Zong You,Li Chia Ying,Lai Kuei Hung,Liao Mei Yi,Wang Wei Hsien,Chung Hsu Ming.
Chemical Constituents from the Octocoral Lobophytum sarcophytoides
. Chemistry of Natural Compounds
.2022
;(58):1167-1169
|
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| 18. |
2022
Chen, Y.-Y.,Chen, L.-Y.,Chen, P.-J.,El-Shazly, M., Peng, B.-R.,Chen, Y.-C.; Su, C.-H.; Su, J.-H.; Sung, P.-J.; Yen, P.-T.; Wang, L.-S.; Lai, K.-H..
Probing Anti-Leukemic Metabolites from Marine-Derived Streptomyces sp. LY1209
. Metabolites
.2022
;(12):320-320
|
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| 19. |
2022
Su Chun Han,Cheng Yu Chieh,Chang Yu Chia,Kung Ting Hsuan,Chen Yu Li,Lai Kuei Hung,Hsieh Hsi Lung,Chen Chun Yu,Hwang Tsong Long,Yang Yu Liang,Su Chun Han,Cheng Yu Chieh,Chang Yu Chia,Kung Ting Hsuan,Chen Yu Li,Lai Kuei Hung,Hsieh Hsi Lung,Chen Chun Yu,Hwang Tsong Long,Yang Yu Liang.
Untargeted LC-MS/MS-Based Multi-Informative Molecular Networking for Targeting the Antiproliferative Ingredients in Tetradium ruticarpum Fruit
. Molecules
.2022
;(27)
|
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| 20. |
2022
Vo Thi Thuy Tien,Huynh Thao Duy,Wang Ching Shuen,Lai Kuei Hung,Lin Zih Chan,Lin Wei Ning,Chen Yuh Lien,Peng Tzu Yu,Wu Ho Cheng,Lee I. Ta,Vo Thi Thuy Tien,Huynh Thao Duy,Wang Ching Shuen,Lai Kuei Hung,Lin Zih Chan,Lin Wei Ning,Chen Yuh Lien,Peng Tzu Yu,Wu Ho Cheng,Lee I. Ta.
The Potential Implications of Hydrogen Sulfide in Aging and Age-Related Diseases through the Lens of Mitohormesis
. Antioxidants
.2022
;(11)
|
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| 21. |
2022
Lai KH*,Chen YL,Lin MF,El-Shazly M,Chang YC,Chen PJ, Su CH, Chiu YC, Illias AM, Chen CC, Chen LY, Hwang TL*.
Lonicerae Japonicae Flos Attenuates Neutrophilic Inflammation by Inhibiting Oxidative Stress
. Antioxidants
.2022
;(11)
|
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| 22. |
2022
Su Chun Han,Cheng Yu Chieh,Lai Kuei Hung,Chang Yu Chia,Sun Chi Hui,Tu Po Wen,Lin Ching Chih,Hwang Tsong Long,Yang Yu Liang,Su Chun Han,Cheng Yu Chieh,Lai Kuei Hung,Chang Yu Chia,Sun Chi Hui,Tu Po Wen,Lin Ching Chih,Hwang Tsong Long,Yang Yu Liang.
Exploring the relationship between metabolite composition and the cold/hot properties ascribed in traditional Chinese medicine by mass spectral molecular networking e A pilot study
. Journal of Food and Drug Analysis
.2022
;(30):402-416
|
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| 23. |
2022
Wu Ching Fang,Hung Tzu Ting,Su Yu Chieh,Chen Po Jen,Lai Kuei Hung,Wang Chih Chun,Wu Ching Fang,Hung Tzu Ting,Su Yu Chieh,Chen Po Jen,Lai Kuei Hung,Wang Chih Chun.
Endoplasmic Reticulum Stress of Oral Squamous Cell Carcinoma Induces Immunosuppression of Neutrophils
. Frontiers in Oncology
.2022
;(12)
|
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| 24. |
2022
Cheng Wei Jen,Yang Hsuan Tzu,Chiang Chih Chao,Lai Kuei Hung,Chen Yu Li,Shih Huei Lin,Kuo Jong Jen,Hwang Tsong Long,Lin Chi Chien,Cheng Wei Jen,Yang Hsuan Tzu,Chiang Chih Chao,Lai Kuei Hung,Chen Yu Li,Shih Huei Lin,Kuo Jong Jen,Hwang Tsong Long,Lin Chi Chien.
Deer Velvet Antler Extracts Exert Anti-Inflammatory and Anti-Arthritic Effects on Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes and Distinct Mouse Arthritis
. American Journal of Chinese Medicine
.2022
;(50):1617-1643
|
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| 25. |
2022
Chen LY,Peng BR,Lai GY,Weng HJ,El-Shazly M,Su CH, Su JH, Sung PJ, Liao CP*, Lai KH*.
Chemometric-Guided Exploration of Marine Anti-Neurofibroma Leads
. Frontiers in Marine Science
.2022
;(9):930736
|
|
| 26. |
2022
Hsieh Chia Ching,Wu Yi Ying,Peng Bo Rong,Lai Kuei Hung,Liao Mei Yi,Chung Hsu Ming,Hsieh Chia Ching,Wu Yi Ying,Peng Bo Rong,Lai Kuei Hung,Liao Mei Yi,Chung Hsu Ming.
Chemical Constituents of the Formosan Soft Coral Sinularia querciformis
. Chemistry of Natural Compounds
.2022
;(58):975-977
|
|
| 27. |
2022
Ke Zong You,Chen Jun Wen,Wu Bo Yan,Jhan Yi Yan,Wen Zhi Hong,Kung Te An,Sung Ping Jyun,Chen Jih Jung,Lai Kuei Hung,Chung Hsu Ming,Ke Zong You,Chen Jun Wen,Wu Bo Yan,Jhan Yi Yan,Wen Zhi Hong,Kung Te An,Sung Ping Jyun,Chen Jih Jung,Lai Kuei Hung,Chung Hsu Ming.
A new angular naphthopyrone from feather star Comanthus parvicirrus (M{\uller, 1841)
. Journal of Molecular Structure
.2022
;(1253)
|
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| 28. |
2022
Wang SH,Chen YS,Lai KH, Lu CK,Chang HS,Wu HC, Yen FL, Chen LY, Lee JC, Yen CH.
Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte
. Antioxidants
.2022
;(11):1755
|
|
| 29. |
2022
Nguyen NBA,Chen LY,El-Shazly M,Peng BR,Su JH,Wu HC, Lee IT, Lai KH.
Towards Sustainable Medicinal Resources through Marine Soft Coral Aquaculture: Insights into the Chemical Diversity and the Biological Potential
. Marine Drugs
.2022
;(20):640
|
|
| 30. |
2021
Lai KH,Peng BR,Hsu YM,El-Shazly M,Du YC,Lu MC, Su JH, Liu YC.
The Configuration-Dependent Anti-Leukemic Effect of Manoalide Stereoisomers: Reignite Research Interest in these Sponge-Derived Sesterterpenoids
. Bioorganic Chemistry
.2021
;(114)
|
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| 31. |
2021
Lai KH*,Huang ZH,El-Shazly M,Peng BR,Wei WC,Su JH*.
Isomalabaricane Triterpenes from the Marine Sponge Rhabdastrella sp
. Marine Drugs
.2021
;(19):206
|
|
| 32. |
2021
Hu HC,Tsai YH,Chuang YC,Lai KH,Hsu YM,Hwang TL, Lin CC, Fülöp F, Wu YC, Yu SY, Kuo YT, Chang FR.
Estrogenic and anti-neutrophilic inflammatory phenanthrenes from Juncus effusus L.
. Natural Product Research
.2021
|
|
| 33. |
2021
Kumar S,Chang YC,Lai KH,Hwang TL.
Resveratrol, a Molecule with Anti-Inflammatory and Anti-Cancer Activities: Natural Product to Chemical Synthesis
. Current Medicinal Chemistry
.2021
|
|
| 34. |
2021
Lai KH,Peng BR,Su CH,El-Shazly M,Sun YL,Shih MC, Huang YT, Yen PT, Wang LS, Su JH.
Anti-proliferative potential of secondary metabolites from the marine sponge theonella sp.: Moving from correlation toward causation
. Metabolites
.2021
;(11)
|
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| 35. |
2021
Lai KH,Chen PJ,Chen CC,Yang SH,El-Shazly M,Chang YC, Wu YH, Wu YH, Wang YH, Hsieh HL, Hwang TL.
Lophatherum gracile Brongn. attenuates neutrophilic inflammation through inhibition of JNK and calcium
. Journal of Ethnopharmacology
.2021
;(264)
|
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| 36. |
2021
Peng BR, Lai KH,Lee GH,Yu SS,Duh CY,Su JH, Zheng LG, Hwang TL, Sung PJ.
Scalarane-Type Sesterterpenoids from the Marine Sponge Lendenfeldia sp. Alleviate Inflammation in Human Neutrophils
. Marine Drugs
.2021
;(19):561
|
|
| 37. |
2021
Wu Yi Ying,Hsieh Chia Ching,Li Chia Ying,Chang Wen Huei,Chen Jih Jung,Lai Kuei Hung,Wen Zhi Hong,Chung Hsu Ming,Wu Yi Ying,Hsieh Chia Ching,Li Chia Ying,Chang Wen Huei,Chen Jih Jung,Lai Kuei Hung,Wen Zhi Hong,Chung Hsu Ming.
Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis
. Natural Product Communications
.2021
;(16)
|
|
| 38. |
2020
Chen PJ,Kuo LM,Wu YH,Chang YC,Lai KH,Hwang TL.
BAY 41-2272 Attenuates CTGF Expression via sGC/cGMP-Independent Pathway in TGFβ1-Activated Hepatic Stellate Cells
. Biomedicines
.2020
|
|
| 39. |
2020
Peng BR,Lai KH,Chang YC,Chen YY,Su JH,Huang YM, Chen PJ, Yu SSF, Duh CY, Sung PJ.
Sponge-Derived 24-Homoscalaranes as Potent Anti-Inflammatory Agents
. Marine drugs
.2020
|
|
| 40. |
2020
Chiang CC,Li YR,Lai KH,Cheng WJ,Lin SC,Wang YH, Chen PJ, Yang SH, Lin CC, Hwang TL.
Aqueous extract of kan-lu-hsiao-tu-tan ameliorates collagen-induced arthritis in mice by inhibiting oxidative stress and inflammatory responses
. Life
.2020
;(10):1-17
|
|
| 41. |
2020
Chang YC,Lai KH,Kumar S,Chen PJ,Wu YH,Lai CL, Hsieh HL, Sung PJ, Hwang TL.
1H NMR-based isolation of anti-inflammatory 9,11-secosteroids from the octocoral sinularia leptoclados
. Marine Drugs
.2020
;(18)
|
|
| 42. |
2020
Chiang CC,Cheng WJ,Lin CY,Lai KH,Ju SC,Lee C, Yang SH, Hwang TL.
Kan-Lu-Hsiao-Tu-Tan, a traditional Chinese medicine formula, inhibits human neutrophil activation and ameliorates imiquimod-induced psoriasis-like skin inflammation
. Journal of Ethnopharmacology
.2020
;(246)
|
|
| 43. |
2020
Peng BR,Lai KH,Chen YY,Su JH,Huang YM,Chen YH, Lu MC, Yu SSF, Duh CY, Sung PJ.
Probing anti-proliferative 24-homoscalaranes from a sponge Lendenfeldia sp.
. Marine Drugs
.2020
;(18)
|
|
| 44. |
2018
Tsai TC,Lai KH,Su JH,Wu YJ,Sheu JH.
7-Acetylsinumaximol b induces apoptosis and autophagy in human gastric carcinoma cells through mitochondria dysfunction and activation of the perk/eif2α/atf4/chop signaling pathway
. Marine Drugs
.2018
;(16)
|
|
| 45. |
2018
Peng BR,Lu MC,El-Shazly M,Wu SL,Lai KH,Su JH.
Aquaculture soft coral lobophytum crassum as a producer of anti-proliferative cembranoids
. Marine Drugs
.2018
;(16)
|
|
| 46. |
2018
Chen YC,Lu MC,El-Shazly M,Lai KH,Wu TY,Hsu YM, Lee YL, Liu YC.
Breaking down Leukemia Walls: Heteronemin, a Sesterterpene Derivative, Induces Apoptosis in Leukemia Molt4 Cells through Oxidative Stress, Mitochondrial Dysfunction and Induction of Talin Expression
. Marine Drugs
.2018
;(16)
|
|
| 47. |
2018
Xu JH,Lai KH,Su YD,Chang YC,Peng BR,Backlund A, Wen ZH, Sung PJ.
Briaviolides k-n, new briarane-type diterpenoids from cultured octocoral briareum violaceum
. Marine Drugs
.2018
;(16)
|
|
| 48. |
2018
Lee MG,Liu YC,Lee YL,El-Shazly M,Lai KH,Shih SP, Ke SC, Hong MC, Du YC, Yang JC, Sung PJ, Wen ZH, Lu MC.
Heteronemin, a marine sesterterpenoid-type metabolite, induces apoptosis in prostate lncap cells via oxidative and er stress combined with the inhibition of topoisomerase II and Hsp90
. Marine Drugs
.2018
;(16)
|
|
| 49. |
2018
Wu CF,Lee MG,El-Shazly M,Lai KH,Ke SC,Su CW, Shih SP, Sung PJ, Hong MC, Wen ZH, Lu MC.
Isoaaptamine induces T-47D cells apoptosis and autophagy via oxidative stress
. Marine Drugs
.2018
;(16)
|
|
| 50. |
2017
Korinek M,Tsai YH,El-Shazly M,Lai KH,Backlund A,Wu SF, Lai WC, Wu TY, Chen SL, Wu YC, Cheng YB, Hwang TL, Chen BH, Chang FR.
Anti-allergic hydroxy fatty acids from Typhonium blumei explored through ChemGPS-NP
. Frontiers in Pharmacology
.2017
;(8)
|
|
| 51. |
2017
Lai KH,You WJ,Lin CC,El-Shazly M,Liao ZJ,Su JH.
Anti-inflammatory cembranoids from the soft coral lobophytum crassum
. Marine Drugs
.2017
;(15)
|
|
| 52. |
2016
Lai KH,Liu YC,Su JH,El-Shazly M,Wu CF,Du YC, Hsu YM, Yang JC, Weng MK, Chou CH, Chen GY, Chen YC, Lu MC.
Antileukemic Scalarane Sesterterpenoids and Meroditerpenoid from Carteriospongia (Phyllospongia) sp., Induce Apoptosis via Dual Inhibitory Effects on Topoisomerase II and Hsp90
. Scientific Reports
.2016
;(6)
|
|
| 53. |
2016
Lai KH,Lu MC,Du YC,El-Shazly M,Wu TY,Hsu YM, Henz A, Yang JC, Backlund A, Chang FR, Wu YC.
Cytotoxic Lanostanoids from Poria cocos
. Journal of Natural Products
.2016
;(79):2805-2813
|
|
| 54. |
2016
Chiu CP,Hwang TL,Chan Y,El-Shazly M,Wu TY,Lo IW, Hsu YM, Lai KH, Hou MF, Yuan SS, Chang FR, Wu YC.
Research and development of Cordyceps in Taiwan
. Food Science and Human Wellness
.2016
;(5):177-185
|
|
| 55. |
2016
Hsu YM,Chang FR,Lo IW,Lai KH,El-Shazly M,Wu TY, Du YC, Hwang TL, Cheng YB, Wu YC.
Zoanthamine-Type Alkaloids from the Zoanthid Zoanthus kuroshio Collected in Taiwan and Their Effects on Inflammation
. Journal of Natural Products
.2016
;(79):2674-2680
|
|
| 56. |
2013
Wu TY,Du YC,Hsu YM,Lu CY,Singab ANB,El-Shazly M, Hwang TL, Lin WY, Lai KH, Lu MC, Tsai YH, Hou MF, Duh TH, Chang FR.
New approach to the characterization and quantification of Antrodia cinnamomea benzenoid components utilizing HPLC-PDA, qNMR and HPLC-tandem MS: Comparing the wild fruiting bodies and its artificial cultivated commercial products
. Food Research International
.2013
;(51):23-31
|
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| 57. |
2013
Lu MC,El-Shazly M,Wu TY,Du YC,Chang TT,Chen CF, Hsu YM, Lai KH, Chiu CP, Chang FR, Wu YC.
Recent research and development of Antrodia cinnamomea
. Pharmacology and Therapeutics
.2013
;(139):124-156
|
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