| 1. |
2024
Kao TW,Chen HH,Lin J,Wang TL,Shen YA.
PBX1 as a novel master regulator in cancer: Its regulation, molecular biology, and therapeutic applications
. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
.2024
;(1879)
|
|
| 2. |
2024
Lin-Yu Chen,Yao-An Shen,Ling-Hui Chu,Po-Hsuan Su,Hui-Chen Wang,Yu-Chun Weng, Shiou-Fu Lin, Kuo-Chang Wen, Phui-Ly Liew, Hung-Cheng Lai.
Active DNA Demethylase, TET1, Increases Oxidative Phosphorylation and Sensitizes Ovarian Cancer Stem Cells to Mitochondrial Complex I Inhibitor
. Antioxidants
.2024
;(13)
|
|
| 3. |
2023
Yao-Chen Chuang,Ping-Hsiu Wu,Yao-An Shen,Chia-Chun Kuo,Wei-Jun Wang,Yu-Chen Chen, Hsin-Lun Lee, Jeng-Fong Chiou.
Recent Advances in Metal-Based NanoEnhancers for Particle Therapy
. Nanomaterials
.2023
;(13)
|
|
| 4. |
2023
Liang-Yun Chen,Ting-Wan Kao,Chang-Cyuan Chen,Noreen Niaz,Hsin-Lun Lee,Yu-Hsin Chen, Chia-Chun Kuo, Yao-An Shen.
Frontier Review of the Molecular Mechanisms and Current Approaches of Stem Cell-Derived Exosomes
. Cells
.2023
;(12)
|
|
| 5. |
2023
Novel Cancer Treatment Paradigm Targeting HIF in Conjunction with Current Therapies to Overcome Resistance
. J Exp Clin Cancer Res
.2023
;(42)
|
|
| 6. |
2023
Glucose Transporter 1-Mediated Transcytosis of Glucosamine-Labeled Liposomal Ceramide Targets Hypoxia Niches and Cancer Stem Cells to Enhance Therapeutic Efficacy
. ACS Nano
.2023
;(17):13158-13175
|
|
| 7. |
2023
Lee HL,Chuang YC,Tsai JT,Chen YC,Wu PH,Lo LW, Chiou JF, Shen YA.
Gold Nanodandelions as Nanozymes and Reactive Oxygen Species Scavengers in Tumor Microenvironment Components
. ACS Appl. Nano Mater.
.2023
;(6):21359-21370
|
|
| 8. |
2022
Trasanidis N,Katsarou A,Ponnusamy K,Shen YA,Kostopoulos IV,Bergonia B, Keren K, Reema P, Xiao X, Szydlo RM, Sabbattini P, Roberts I, Auner HW, Naresh KN, Chaidos A, Wang TL, Magnani L, Caputo VS, Karadimitris A.
Systems medicine dissection of chr1q-amp reveals a novel PBX1-FOXM1 axis for targeted therapy in multiple myeloma
. Blood
.2022
|
|
| 9. |
2022
Fang-Chi Hsu,Hsin-Lun Lee,Yin-Ju Chen,Yao-An Shen,Yi-Chieh Tsai,Meng-Huang Wu, Chia-Chun Kuo, Long-Sheng Lu, Shauh-Der Yeh, Wen-Sheng Huang, Chia-Ning Shen, Jeng-Fong Chiou.
A Few-Shot Learning Approach Assists in the Prognosis Prediction of Magnetic Resonance-Guided Focused Ultrasound for the Local Control of Bone Metastatic Lesions
. Cancers
.2022
;(14)
|
|
| 10. |
2022
Jiaxin Hong,Yao-An Shen,Chih-Yi Hsu,Peng Huang,Alicja Tomaszewski,Edward Gabrielson, Ie-Ming Shih, Stephanie Gaillard, Tian-Li Wang.
Targeting glutamine metabolism enhances responses to platinum-based chemotherapy in triple-negative breast cancers (TNBC)
. Genes & Diseases
.2022
;(9):1408-1411
|
|
| 11. |
2022
Ting-Wan Kao,Yao-Chen Chuang,Hsin-Lun Lee,Chia-Chun Kuo,Yao-An Shen.
Therapeutic Targeting of Glutaminolysis as a Novel Strategy to Combat Cancer Stem Cells
. International Journal of Molecular Sciences
.2022
|
|
| 12. |
2021
Shen YA,Chen CL,Huang YH,Evans EE,Cheng CC,Chuang YJ, Zhang C, Le A.
Inhibition of glutaminolysis in combination with other therapies to improve cancer treatment
. Current Opinion in Chemical Biology
.2021
;(62):64-81
|
|
| 13. |
2021
Yao-An Shen,Jin Jung,Geoffrey D Shimberg,Fang-Chi Hsu,Yohan Suryo Rahmanto,Stephanie L Gaillard, Jiaxin Hong, Jürgen Bosch, Ie-Ming Shih, Chi-Mu Chuang, Tian-Li Wang.
Development of small molecule inhibitors targeting PBX1 transcription signaling as a novel cancer therapeutic strategy
. iScience
.2021
;(24)
|
|
| 14. |
2021
Yao-An Shen,Chang-Cyuan Chen,Bo-Jung Chen,Yu-Ting Wu,Jiun-Ru Juan,Liang-Yun Chen, Yueh-Chun Teng, Yau-Huei Wei.
Potential Therapies Targeting Metabolic Pathways in Cancer Stem Cells
. Cells
.2021
;(10)
|
|
| 15. |
2021
Hsin-Pei Weng,Yuan-Yang Cheng,Hsin-Lun Lee,Tai-Yi Hsu,Yu-Tang Chang,Yao-An Shen.
Enhanced Platelet-Rich Plasma (ePRP) Stimulates Wound Healing through Effects on Metabolic Reprogramming in Fibroblasts
. International Journal of Molecular Sciences
.2021
;(22)
|
|
| 16. |
2020
Targeting Cancer Stem Cells from a Metabolic Perspective
. Experimental Biology and Medicine
.2020
;(245):465-476
|
|
| 17. |
2020
Shen YA,Hong J,Asaka R,Asaka S,Hsu FC,Suryo Rahmanto Y, Jung JG, Chen YW, Yen TT, Tomaszewski A, Zhang C, Attarwala N, DeMarzo AM, Davidson B, Chuang CM, Chen X, Gaillard S, Le A, Shih IM, Wang TL.
Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers
. Cancer Research
.2020
;(80):4514-4526
|
|
| 18. |
2019
Yu Y,Rahmanto YS,Shen YA,Ardighieri L,Davidson B,Gaillard S, Ayhan A, Shi X, Xuan J, Wang TL, Shih IM.
Spleen tyrosine kinase activity regulates epidermal growth factor receptor signaling pathway in ovarian cancer
. EBioMedicine
.2019
;(47):184-194
|
|
| 19. |
2019
Nguyen T,Kirsch BJ,Asaka R,Nabi K,Quinones A,Tan J, Antonio MJ, Camelo F, Li T, Nguyen S, Hoang G, Nguyen K, Udupa S, Sazeides C, Shen YA, Elgogary A, Reyes J, Zhao L, Kleensang A, Chaichana KL, Hartung T, Betenbaugh MJ, Marie SK, Jung JG, Wang TL, Gabrielson E, Le A.
Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cancer
. Cell Reports
.2019
;(27):491-501
|
|
| 20. |
2019
Yu LY,Shen YA,Chen MH,Wen YH,Hsieh PI,Lo CL.
The feasibility of ROS- and GSH-responsive micelles for treating tumor-initiating and metastatic cancer stem cells
. J. Mater. Chem. B
.2019
;(7):3109-3118
|
|
| 21. |
2018
Debele TA,Yu LY,Yang CS,Shen YA,Lo CL.
pH- and GSH-sensitive hyaluronic acid-mp conjugate micelles for intracellular delivery of doxorubicin to colon cancer cells and cancer stem cells
. Biomacromolecules
.2018
;(19):3725-3737
|
|
| 22. |
2017
Debele TA,Lee KY,Hsu NY,Chiang YT,Yu LY,Shen YA, Lo CL.
A pH sensitive polymeric micelle for co-delivery of doxorubicin and a-TOS for colon cancer therapy
. J. Mater. Chem. B
.2017
;(5):5870-5880
|
|
| 23. |
2016
Shen YA,Wang CY,Chuang HY,Hwang JJ,Chi WH,Shu CH, Ho CY, Li WY, Chen YJ.
CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation
. Oncotarget
.2016
;(7):58351-58366
|
|
| 24. |
2016
Shen YA,Lan KL,Chang CH,Lin LT,He CL,Cheng PH, Lee TW, Lee YJ, Chuang CM.
Intraperitoneal 188Re-Liposome delivery switches ovarian cancer metabolism from glycolysis to oxidative phosphorylation and effectively controls ovarian tumour growth in mice
. Radiother Oncol
.2016
;(119):282-290
|
|
| 25. |
2015
Shen YA,Li WH,Chen PH,He CL,Chang YH,Chuang CM.
Intraperitoneal delivery of a novel liposome-encapsulated paclitaxel redirects metabolic reprogramming and effectively inhibits cancer stem cells in Taxol®-resistant ovarian cancer
. Am J Transl Res
.2015
;(7):841-855
|
|
| 26. |
2015
Shen YA,Liu CS,Chang YH,Chen PH,He CL,Wu HC, Chuang CM.
Subtype-specific binding peptides enhance the therapeutic efficacy of nanomedicine in the treatment of ovarian cancer
. Cancer Letters
.2015
;(360):39-47
|
|
| 27. |
2015
Shen YA,Lu M,Shyu IL,Hsu YM,Liang HF,Liu CP, Wei MC, Tsai YJ, Wei YH.
Bypassing The EPR Effect Confers Better Tumor Control with Nanomedicine Harboring Sustained-Release Function
. International Journal of Nanomedicine
.2015
;(10):2485-2502
|
|
| 28. |
2015
Shen YA,Wang CY,Hsieh YT,Chen YJ,Wei YH.
Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma
. Cell Cycle
.2015
;(14):86-98
|
|
| 29. |
2013
Shen YA,Lin CH,Chi WH,Wang CY,Hsieh YT,Wei YH, Chen YJ.
Resveratrol impedes the stemness, epithelial-mesenchymal transition, and metabolic reprogramming of cancer stem cells in nasopharyngeal carcinoma through p53 activation
. Evid Based Complement Alternat Med
.2013
;(2013):590393
|
|
| 30. |
2012
Lin CH,Shen YA,Hung PH,Yu YB,Chen YJ.
Epigallocathechin Gallate, Polyphenol Present in Green Tea, Inhibits Stem-Like Characteristics and Epithelial-Mesenchymal Transition in Nasopharyngeal Cancer Cell Lines
. BMC Complement Altern Med
.2012
;(12):201
|
|
| 31. |
2012
Lin CS,Lee HT,Lee SY,Shen YA,Wang LS,Chen YJ, Wei YH.
High Mitochondrial DNA Copy Number and Bioenergetic Function Are Associated With Tumor Invasion of Esophageal Squamous Cell Carcinoma Cell Lines
. Int J Mol Sci
.2012
;(13):11228-11246
|
|