林育嬋(Lin, Yu-Charn) 助理教授

Email
yuhcharnlin@tmu.edu.tw
現   職
生理學科 助理教授

學經歷

學 歷

畢業學校與學位[修業時間]
國防醫學院生命科學研究所 博士
2009/08~2015/01
弘光科技大學生物科技研究所 碩士
2004/08~2006/06
弘光科技大學食品營養系 學士
2002/08~2004/06

本校學術經歷

任職單位與職稱[起迄時間]
生理學科助理教授
2022/07/25~

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
中央研究院生物醫學科學研究所研究學者
2020/08~2022/07
中央研究院生物醫學科學研究所助理研究學者
2018/08~2020/07
中央研究院博士後研究員
2015/01~2018/07
中央研究院研究助理
2008/03~2009/08

專長與研究領域

學門領域
學術專長
細胞訊息傳遞學
細胞訊息傳遞學
心臟血管生理學
心臟血管生理學
血管生物學
血管生物學
血管新生
血管新生
癌症分子醫學
癌症分子醫學

論文著作

清冊下載


1. 2024 Yuh-Charn Lin,Ya-Jen Chang,Shiang-Shin Gau,Chun-Min Lo,Ruey-Bing Yang. SCUBE2 regulates adherens junction dynamics and vascular barrier function during inflammation . Cardiovascular Research .2024

2. 2023 Lin YC,Sahoo BK,Gau SS,Yang RB. The Biology of SCUBE . Journal of biomedical Science .2023

3. 2023 Dhawan U,Wang WL,Lin YC,Yang RB,Dalby MJ,Salmeron-Sanchez M, Yu HH. Mechanostimulation-induced integrin αvβ6 and Latency Associated Peptide coupling activates TGF-β and regulates cancer metastasis and stemness . Nano Today .2023

4. 2022 Sahoo Binay K,Lin Yuh-Charn,Tu Cheng-Fen,Lin Chien-Chin,Liao Wei-Ju,Li Fu-An,Li Ling-Hui,Mou Kurt Yun,Roffler Steve R,Wang Shu-Ping,Yeh Chi-Tai,Yao Chi-Yuan,Hou Hsin-An,Chou Wen-Chien,Tien Hwei-Fang,Yang Ruey-Bing,Sahoo Binay K,Lin Yuh-Charn,Tu Cheng-Fen,Lin Chien-Chin,Liao Wei-Ju,Li Fu-An,Li Ling-Hui,Mou Kurt Yun,Roffler Steve R,Wang Shu-Ping,Yeh Chi-Tai,Yao Chi-Yuan,Hou Hsin-An,Chou Wen-Chien,Tien Hwei-Fang,Yang Ruey-Bing. Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia . Haematologica .2022

5. 2022 Tsao Ku Chi,Lin Yuh Charn,Chen Yi Ting,Lai Shih Lei,Yang Ruey Bing,Tsao Ku Chi,Lin Yuh Charn,Chen Yi Ting,Lai Shih Lei,Yang Ruey Bing. Zebrafish Scube1 and Scube2 cooperate in promoting Vegfa signalling during embryonic vascularization . Cardiovascular Research .2022 ;(118):1074-1087

6. 2022 Liu Yingzi,Guerrero-Juarez Christian F.,Xiao Fei,Shettigar Nitish Udupi,Ramos Raul,Kuan Chen Hsiang,Lin Yuh Charn,de Jesus Martinez Lomeli Luis,Park Jung Min,Oh Ji Won,Liu Ruiqi,Lin Sung Jan,Tartaglia Marco,Yang Ruey Bing,Yu Zhengquan,Nie Qing,Li Ji,Plikus Maksim V.,Liu Yingzi,Guerrero-Juarez Christian F.,Xiao Fei,Shettigar Nitish Udupi,Ramos Raul,Kuan Chen Hsiang,Lin Yuh Charn,de Jesus Martinez Lomeli Luis,Park Jung Min,Oh Ji Won,Liu Ruiqi,Lin Sung Jan,Tartaglia Marco,Yang Ruey Bing,Yu Zhengquan,Nie Qing,Li Ji,Plikus Maksim V.. Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state . Developmental Cell .2022 ;(57):1758-1775.e7

7. 2022 Chou Pei Chun,Liu Chih Min,Weng Ching Hui,Yang Kai Chien,Cheng Mei Ling,Lin Yuh Charn,Yang Ruey Bing,Shyu Bai Chuang,Shyue Song Kun,Liu Jin Dian,Chen Shih Pin,Hsiao Michael,Hu Yu Feng,Chou Pei Chun,Liu Chih Min,Weng Ching Hui,Yang Kai Chien,Cheng Mei Ling,Lin Yuh Charn,Yang Ruey Bing,Shyu Bai Chuang,Shyue Song Kun,Liu Jin Dian,Chen Shih Pin,Hsiao Michael,Hu Yu Feng. Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes . Circulation Research .2022 ;(131):6-20

8. 2022 Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats . Nature Biomedical Engineering .2022 ;(6):421-434

9. 2021 Lin YC,Niceta M,Muto V,Vona B,Pagnamenta AT,Maroofian R, Beetz C, Duyvenvoorde HV, Dentici ML, Lauffer P, Vallian S, Ciolfi A, Pizzi S, Bauer P, Gruning NM, Bellacchio E, Fattore AD, Petrini S, Shaheen R, Tiosano D, Halloun R, Pode-Shakked B, Albayrak HM, Isik E, Wit JM, Dittrich M, Freire BL, Bertola DR, Jorge AAL, Barel O, Sabir AH, Tenaiji AMJA, Taji SM, Al-Sannaa N, Al-Abdulwahed H, Digilio MC, Irving M, Anikster Y, Bhavani GSL, Girisha KM, Genomics England Research Consortium, Haaf T, Taylor JC, Dallapiccola B, Alkuraya FS, Yang RB. SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling . American Journal of Human Genetics .2021 ;(108):1-19

10. 2018 Lin Yuh Charn,Liu Chun Yu,Kannagi Reiji,Yang Ruey Bing,Lin Yuh Charn,Liu Chun Yu,Kannagi Reiji,Yang Ruey Bing. Inhibition of endothelial SCUBE2 (signal peptide-CUB-EGF domain-containing protein 2), a Novel VEGFR2 (vascular endothelial growth factor receptor 2) coreceptor, suppresses tumor angiogenesis . Arteriosclerosis, Thrombosis, and Vascular Biology .2018 ;(38):1202-1215

11. 2018 Yeh Hsi Wen,Hsu En Chi,Lee Szu Shuo,Lang Yaw Dong,Lin Yuh Charn,Chang Chieh Yu,Lee Suz Yi,Gu De Leung,Shih Jou Ho,Ho Chun Ming,Chen Chian Feng,Chen Chiung Tong,Tu Pang Hsien,Cheng Ching Feng,Chen Ruey Hwa,Yang Ruey Bing,Jou Yuh Shan,Yeh Hsi Wen,Hsu En Chi,Lee Szu Shuo,Lang Yaw Dong,Lin Yuh Charn,Chang Chieh Yu,Lee Suz Yi,Gu De Leung,Shih Jou Ho,Ho Chun Ming,Chen Chian Feng,Chen Chiung Tong,Tu Pang Hsien,Cheng Ching Feng,Chen Ruey Hwa,Yang Ruey Bing,Jou Yuh Shan. PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis . Nature Cell Biology .2018 ;(20):479-491

12. 2018 Chen Jia Hong,Kuo Kuang Tai,Bamodu Oluwaseun Adebayo,Lin Yuh Charn,Yang Ruey Bing,Yeh Chi Tai,Chao Tsu Yi,Chen Jia Hong,Kuo Kuang Tai,Bamodu Oluwaseun Adebayo,Lin Yuh Charn,Yang Ruey Bing,Yeh Chi Tai,Chao Tsu Yi. Upregulated SCUBE2 expression in breast cancer stem cells enhances triple negative breast cancer aggression through modulation of notch signaling and epithelial-to-mesenchymal transition . Experimental Cell Research .2018 ;(370):444-453

研究計畫

計畫名稱
112 闡明SCUBE蛋白家族對血栓形成與心臟修復之分子機制(3/3)
補助單位
國家科學及技術委員會

計畫名稱
112 探究Galectin-9調控內皮細胞與巨噬細胞之交互作用影響慢性腎病變進程
補助單位
國家科學及技術委員會

計畫名稱
111 新聘教師研究補助
補助單位
臺北醫學大學

計畫名稱
111 闡明SCUBE蛋白家族對血栓形成與心臟修復之分子機制(2/3)
補助單位
國家科學及技術委員會