王三源(Wang, San-Yuan) 副教授

Email
syw@tmu.edu.tw
現   職
臨床基因體學暨蛋白質體學碩士學位學程 副教授

學經歷

學 歷

畢業學校與學位[修業時間]
國立臺灣大學資訊工程所 博士
2010/09~2014/01
靜宜大學資訊管理所 碩士
2004/09~2006/06
靜宜大學資訊管理所 學士
2000/09~2004/06

本校學術經歷

任職單位與職稱[起迄時間]
臨床基因體學暨蛋白質體學碩士學位學程副教授
2023/08/01~
臨床基因體學暨蛋白質體學碩士學位學程助理教授
2021/08/01~2023/07/31
(舊)臨床藥物基因體學暨蛋白質體學碩士學位學程助理教授
2017/09/20~2021/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
藥物科學學科助理教授
2019/11/01 ~

其它經歷

任職單位與職稱[起迄時間]
國立臺灣大學博士後研究員
2014/03/04~2017/09/19

專長與研究領域

學門領域
學術專長
系統生物學及Omics資料分析
Systems Biology and Omics Analysis
質譜分析
mass spectrometry

論文著作

清冊下載


1. 2024 Hsu WH,Wang SY,Chao YM,Chang KV,Han DS,Lin YL. Novel metabolic and lipidomic biomarkers of sarcopenia . Journal of Cachexia, Sarcopenia and Muscle .2024

2. 2024 Cheng YH,Lee CH,Wang SY,Chou CY,Yang YJ,Kao CC, Wu HY, Dong Y, Hung WY, Su CY, Tseng ST, Tsai IL. Multiplexed Antibody Glycosylation Profiling Using Dual Enzyme Digestion and Liquid Chromatography-Triple Quadrupole Mass Spectrometry Method . Molecular & Cellular Proteomics .2024

3. 2024 Chiu LW,Ku YE,Chan FY,Lie WN,Chao HJ,Wang SY,Shen WC ,Chen HY . Machine learning algorithms to predict colistin-induced nephrotoxicity from electronic health records in patients with multidrug-resistant Gram-negative infection . International Journal of Antimicrobial Agents .2024

4. 2024 Chou CY,Cheng CY,Lee CH,Kuro-O M,Chen TH,Wang SY, Chuang YK, Yang YJ, Lin YH, Tsai IL. Unveiling unique effector function-related bulk antibody profiles in long-term hemodialysis patients following COVID-19 mRNA booster vaccination . Journal of Microbiology, Immunology and Infection .2024

5. 2024 Liu TW,Lin PY,Chu MH ,Wang SY ,Lee CK. A rapid optimization method for Sepbox system separation using HPTLC: an application of Cerbera manghas L. separation . Analytical Methods .2024

6. 2023 Wang SY,Weng TI,Chen JY,Lee NC,Lee KC,Lai ML, Chien YH, Hwu WL, Chen GY. An automated workflow on data processing (AutoDP) for semiquantitative analysis of urine organic acids with GC-MS to facilitate diagnosis of inborn errors of metabolism . Clinica Chimica Acta .2023

7. 2022 Huang SH,Chu CY,Hsu YC,Wang SY,Kuo LN,Bai KJ, Yu MC, Chang JH, Liu EH, Chen HY. How Platinum-Induced Nephrotoxicity Occurs? Machine Learning Prediction in Non-Small Cell Lung Cancer Patients . Computer Methods and Programs in Biomedicine .2022

8. 2022 Chen HF,Kao CC,Ka SM,Wang SY,Chen M X,Chen GY, Wang TI, Lai RY, Yeh SC, Lin YC, Chen HH, Chang WC, Wu, MS, Tsia IL. Development of an Enrichment-Free One-Pot Sample Preparation and Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry Method to Identify Immunoglobulin a1 Hinge Region O-Glycoforms for Immunoglobulin a Nephropathy . Journal of Chromatography A .2022

9. 2022 Brahmadhi A,Chuang YK,Wang SY,Kao CC,Tsai IL. Exosomal proteomics in kidney disease: From technical approaches to clinical applications . Journal of Food and Drug Analysis .2022

10. 2021 Kao CC,Wang SY,Chuang YK,Lee WY,Chang WC,Wu MS, Tsai IL. Clinical Mass Spectrometry Discovered Human Igg Sialylation as a Potential Biosignature for Kidney Function . Journal of Personalized Medicine .2021

11. 2021 Brahmadhi A,Chen M X,Wang SY,Cho YY,Yu MC,Lee CH, Tsai IL. Determination of fluoroquinolones in dried plasma spots by using microwave-assisted extraction coupled to ultra-high performance liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring . Journal of Pharmaceutical and Biomedical Analysis .2021

12. 2021 Tseng ZR,Wei CC,Wang SY,Liao HW. Discovery and quantification of Irgacure-907 in commercial cow milk by using untargeted liquid chromatography high-resolution mass spectrometry . Journal of Food Composition and Analysis .2021

13. 2021 Liu LC,Ho MY,Su BH,Wang SY,Hsu MT,Tseng Y J. PanGPCR: predictions for multiple targets, repurposing and side effects . Bioinformatics .2021

14. 2021 Chen JY,Chen GY,Wang SY,Fang CC,Chen LY,Weng TI. Development of an analytical method to detect simultaneously 219 new psychoactive substances and 65 other substances in urine specimens using LC-QqQ MS/MS with CriticalPairFinder and TransitionFinder . Talanta .2021

15. 2021 Wang SY,Liao SY. Discovery of Natural Veterinary Herbal Medicine Products in Commercial Cow Milk by Using Nontargeted Profiling on LC–ESI–TOF Platform . Food Analytical Methods .2021

16. 2021 Jheng YT,Putri D U,Chuang HC,Lee KY,Chou HC,Wang SY, Han CL. Prolonged exposure to traffic-related particulate matter and gaseous pollutants implicate distinct molecular mechanisms of lung injury in rats . Particle and Fibre Toxicology .2021

17. 2021 Tsai JS,Wang SY,Chang CH,Chen CY,Wen CJ,Chen GY, Kuo CH, Tseng, Y. J Chen CH. Identification of traumatic acid as a potential plasma biomarker for sarcopenia using a metabolomics-based approach . J Cachexia Sarcopenia Muscle .2021

18. 2021 Chen MX,Su HH,Shiao CY,Chang YT, Chang MC,Kao CC, Wang SY, Shih HC, Tsai IL. Affinity Purification Coupled to Stable Isotope Dilution LC-MS/MS Analysis to Discover IgG4 Glycosylation Profiles for Autoimmune Pancreatitis . Journal of Molecular Sciences .2021

19. 2020 Kuo TC,Tan CE,Wang SY,Lin O A,Su BH,Hsu MT, Lin J, Cheng YY, Chen CS, Yang YC, Chen KH, Lin SW, Ho CC, Kuo CH, Tseng Y J. Human Breathomics Database . Database .2020

20. 2020 Han CL,Sheng YC,Wang SY,Chen YH,Kang JH. Serum proteome profiles revealed dysregulated proteins and mechanisms associated with fibromyalgia syndrome in women . Scientific Reports .2020

21. 2020 Liu LC,Ho MY,Su BH,Wang SY,Hsu MT,Tseng Y J. PanGPCR: Predictions for Multiple Targets, Repurposing and Side Effects . Bioinformatics .2020

22. 2020 Tseng ZR,Wei CC,Wang SY,Liao HW. Discovery and quantification of Irgacure-907 in commercial cow milk by using untargeted liquid chromatography high-resolution mass spectrometry . Journal of Food and Composition and Analysis .2020

23. 2019 Chen MX,Wang SY,Kuo CH,Tsai IL. Metabolome analysis for investigating host-gut microbiota interactions . Journal of the Formosan Medical Association .2019

24. 2019 Shih HC,Chang MC,Chen CH,Tsai IL,Wang SY,Kuo YP, Chen CH, Chang YT. High accuracy differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma by immunoglobulin G glycosylation . Clinical Proteomics .2019 ;(16):1

25. 2019 Chepyala D,Kuo HC,Su KY,Liao HW,Wang SY, Chepyala S R, Chang LC, Kuo CH. Improved Dried Blood Spot-Based Metabolomics Analysis by a Postcolumn Infused-Internal Standard Assisted Liquid Chromatography-Electrospray Ionization Mass Spectrometry Method . Analytical chemistry .2019

26. 2017 Su BH,Shen MY,Harn YC,Wang SY,Schurz A,Lin C, Lin O A, Tseng Y J. An efficient computer-aided structural elucidation strategy for mixtures using an iterative dynamic programming algorithm . Journal of Cheminformatics .2017 ;(9):57

27. 2017 Chao HC,Chen GY,Hsu LC,Liao HW,Yang SY,Wang SY, Li YL, Tang SC, Tseng Y J, Kuo CH. Using precursor ion scan of 184 with liquid chromatography-electrospray ionization-tandem mass spectrometry for concentration normalization in cellular lipidomic studies . Analytica Chimica Acta .2017 ;(971):68-77

28. 2016 Tian TF,Wang SY,Kuo TC,Tan CE,Chen GY,Kuo CH, Chen CH S, Chan CC, Lin O A, Tseng Y J. Web Server for Peak Detection, Baseline Correction, and Alignment in Two-Dimensional Gas Chromatography Mass Spectrometry-Based Metabolomics Data . Analytical Chemistry .2016 ;(88):10395-10403

29. 2016 Tzeng TH,Kuo CY,Wang SY,Huang PK,Huang YM,Hsieh WC, Huang YJ, Kuo PH, Yu SA, Lee SC, Tseng Y J, Tian WC, Lu SS. A Portable Micro Gas Chromatography System for Lung Cancer Associated Volatile Organic Compound Detection . IEEE Journal of Solid-State Circuits .2016 ;(51):259-272

30. 2015 Chen HH,Tseng Y J,Wang SY,Tsai YS,Chang CS,Kuo TC, Yao WJ, Shieh CC, Wu CH, Kuo PH. The metabolome profiling and pathway analysis in metabolic healthy and abnormal obesity . International Journal of Obesity .2015 ;(39):1241-1248

31. 2015 Wang SY,Kuo CH,Tseng Y J. Ion Trace Detection Algorithm to Extract Pure Ion Chromatograms to Improve Untargeted Peak Detection Quality for Liquid Chromatography/Time-of-Flight Mass Spectrometry-Based Metabolomics Data . Analytical Chemistry .2015 ;(87):3048-3055

32. 2013 Liu CT,Raghu R,Lin SH,Wang SY,Kuo CH,Tseng Y J, Sheen, LY. Metabolomics of Ginger Essential Oil against Alcoholic Fatty Liver in Mice . Journal of Agricultural and Food Chemistry .2013 ;(61):11231-11240

33. 2013 Tseng Y J,Kuo CT,Wang SY,Liao HW,Chen GY,Ku YL, Shao WC, Kuo CH. Metabolomic characterization of rhubarb species by capillary electrophoresis and ultra-high-pressure liquid chromatography . ELECTROPHORESIS .2013 ;(34):2918-2927

34. 2013 Huang CC,McDermott M M,Liu K,Kuo CH,Wang SY,Tao H, Tseng Y J. Plasma metabolomic profiles predict near-term death among individuals with lower extremity peripheral arterial disease . Journal of Vascular Surgery .2013 ;(58):989-996

35. 2013 Tsai IL,Kuo TC,Ho TJ,Harm YC,Wang SY,Fu WM, Kuo CH, Tseng Y J. Metabolomic Dynamic Analysis of Hypoxia in MDA-MB-231 and the Comparison with Inferred Metabolites from Transcriptomics Data . Cancers .2013 ;(5):491-510

36. 2013 Ho TJ,Kuo CH,Wang SY,Tseng Y J. True ion pick (TIPick): a denoising and peak picking algorithm to extract ion signals from liquid chromatography/mass spectrometry data . Journal of Mass Spectrometry .2013 ;(48):234-242

37. 2013 Wang SY,Kuo CH,Tseng Y J. Batch Normalizer: A Fast Total Abundance Regression Calibration Method to Simultaneously Adjust Batch and Injection Order Effects in Liquid Chromatography/Time-of-Flight Mass Spectrometry-Based Metabolomics Data and Comparison with Current Calibration Methods . Analytical Chemistry .2013 ;(85):1037-1046

38. 2013 Tsai DM,Kang JJ,Lee SS,Wang SY,Tsia IL,Chen GY, Liao HW, Li WC, Kuo CH, Tseng Y J. Metabolomic Analysis of Complex Chinese Remedies: Examples of Induced Nephrotoxicity in the Mouse from a Series of Remedies Containing Aristolochic Acid . Evidence-Based Complementary and Alternative Medicine .2013

39. 2013 Wang KC,Wang SY,Kuo CH,Tseng Y J. Distribution-Based Classification Method for Baseline Correction of Metabolomic 1D Proton Nuclear Magnetic Resonance Spectra . Analytical Chemistry .2013 ;(85):1231-1239

40. 2012 Kuo CH,Wang KC,Tian TF,Tsai MH,Chiung YM,Hsiech CM, Tsai SJ, Wang SY, Tsai DM, Huang CC, Tseng Y J. Metabolomic Characterization of Laborers Exposed to Welding Fumes . Chemical Research in Toxicology .2012 ;(25):676-686

41. 2010 Wang SY,Ho TJ,Kuo CH,Tseng Y J. Chromaligner: a web server for chromatogram alignment . Bioinformatics .2010 ;(26):2338-2339

研究計畫

計畫名稱
110 開發混合型機器學習之代謝物滯留時間預測模型用於辨識液相層析串聯質譜儀實驗之代謝物(2/2)
補助單位
科技部

計畫名稱
109 開發混合型機器學習之代謝物滯留時間預測模型用於辨識液相層析串聯質譜儀實驗之代謝物(1/2)
補助單位
科技部

計畫名稱
108 人體代謝物之串聯式質譜圖資料庫建置
補助單位
圖爾思生物科技股份有限公司

計畫名稱
106 新聘教師研究補助
補助單位
臺北醫學大學