陳玫潔(Chen, Mei-Chieh)　副教授

Email
mcchen@tmu.edu.tw
現   職
微生物免疫學科 副教授

學經歷

學　歷

畢業學校與學位[修業時間]
國立陽明大學微生物及免疫學研究所 博士
1997/09/01~2002/01/31
國立陽明大學微生物及免疫學研究所 碩士
1994/09/01~1996/06/01
私立臺北醫學院公共衛生學系 學士
1990/09/01~1994/06/01

本校學術經歷

任職單位與職稱[起迄時間]
微生物免疫學科副教授
2016/02/01~
微生物免疫學科助理教授
2015/08/01~2016/01/31
微生物免疫學科助理教授
2014/08/01~2015/07/31
微生物免疫學科助理教授
2003/02/01~2014/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
醫學科學研究所助理教授
2007/08/01 ~

其它經歷

任職單位與職稱[起迄時間]
陽明大學博士後研究
2002/02~2003/01

專長與研究領域

學門領域
微生物免疫
Microbiology and Immunology
學術專長

論文著作

清冊下載

論文 Journal Paper


1. 2023 Yu-Ping Hung,Chia-Ling Chen,Po-Chun Tseng,Rahmat Dani Satria,Mei-Chieh Chen,Chiou-Feng Lin. Measurement of lipid droplets in peripheral immune cells shows an immunomodulatory effect on monocyte polarization in experimental dyslipidaemia . Biochemical and Biophysical Research Communications .2023

2. 2023 Hsi-Hsien Chen,Ya-Li Huang,Mei-Chieh Chen ,Chih-Yin Wu,Ying-Chin Lin,Horng-Sheng Shiue, Sheng-Lun Hsu, Yu-Mei Hsueh. Chronic Kidney Disease: Interaction of Adiponectin Gene Polymorphisms and Diabetes . International Journal o f Molecular Sciences .2023 ;( 24):8128

3. 2017 Chen MC,Tsai YC,Tseng JH, Liou JJ, Horng S, Wen HC, Fan YC, Zhong WB, Hsu SP. Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic Thyroid Cancer . International Journal of Molecular Sciences .2017 ;(18):E2690

4. 2016 Lin CH,Wang YH,Chen YW,YL Lin,Chen BC,Chen MC. Transcriptional and posttranscriptional regulation of CXCL8/IL-8 gene expression induced by connective tissue growth factor. . Immunologic Research .2016 ;(64):369-384

5. 2015 Lin CH,Wang YH,Chen YW,YL Lin,Chen BC,Chen MC. Transcriptional and posttranscriptional regulation of CXCL8/IL-8 gene expression induced by connective tissue growth factor . Immunologic Research .2015 ;(10.100):1-16

6. 2015 Yeh DYW,Chin YP,Wu CC,Lu CJ,Wang YH,Chen MC. Mechanisms of human lymphotoxin beta receptor activation on upregulation of CCL5/RANTES production . International immunopharmacology .2015 ;(28):220-229

7. 2015 ChuangYF,Chen MC,Huang SW,Hsu YF,Ou G,Tsai YJ, Hsu MJ. Protein phosphatase 2A mediates lipopolysaccharide-induced cyclooxygenase-2 expression in murine lymphatic endothelial cells . PLOS ONE .2015 ;(10):1-20

8. 2014 Chin YP,Chang SF,Tseng CC,Chen MC. Escherichia coli Capsular polysaccharide synthesis, antibiotic susceptibility, and RBC agglutination . The Journal of Experimental and Clinical Medicine .2014 ;(6):16-20

9. 2014 Su CM*, Chen MC*,Lin IC,Chen HA,Huang MT,Wu CH,Shen KH, Wang YH. Association between the SULT1A1 Arg213His polymorphism and the risk of bladder cancer: a meta-analysis. . Tumor Biol. .2014 ;(35):7147-53

10. 2014 Pan CH,Liu WT,Bien MY,Lin IC,Hsiao TC, Ma CM, Lai CH, Chen MC, Chuang KJ, Chuang HC. Effects of size and surface of zinc oxide nanoparticles on cell viability inferred by proteomic analyses . International Journal of Nanomedicine .2014 ;(9):3631-43

11. 2014 Su FH,Chen MC,Liu CS,Huang YC,Lin CC,Sung FC, Su CT, Yeh CC. Peroxisome proliferator-activated receptor gamma genetic polymorphisms are not associated with metabolic syndrome in Taiwan . Journal of Experimental and Clinical Medicine .2014 ;(6):195-199

12. 2013 Chin YP,Chang SF,Tseng CC,Chen MC. Escherichia coli Capsular polysaccharide synthesis, antibiotic susceptibility, and RBC agglutination. . The Journal of Experimental and Clinical Medicine .2013 ;(Accept)

13. 2013 Wu CC,Chen MC,Huang YK,Huang CY,Lai LA,Chung CJ, Shiue HS, Pu YS, Lin YC, Han BC, Hsue YM. Environmental tobacco smoke and arsenic methylation capacity are associated with urothelial Carcinoma . Journal of the Formosan Medical Association .2013 ;(112):554-60

14. 2012 Weng HY,Hsu MJ,Wang CC,Chen BC,Hong CY,Chen MC, Chiu WT, Lin CH. Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells . J Biomed Sci .2012 ;(19):86-97

15. 2012 Chin YP*.Tsui KC*,Chen MC,Wang CY,Yang CY,Lin YL. Bactericidal activity of soymilk fermentation broth by in vitro and animal models. . J Med Food .2012 ;(15):520-526

16. 2012 Chin YP, Tsui KC,Chen MC,Wang CY,Yang CY,Lin YL. Bactericidal activity of soymilk fermentation broth by in vitro and animal models. . J Med Food. .2012 ;(15):520-526

17. 2012 Chien PJ,Yeh JH,Shih CM,Hsueh YM,Chen MC,Chiu HC. A Decrease in the Percentage of CD3(+) Cells Is Correlated With Clinical Improvement During Plasmapheresis in Patients With Myasthenia Gravis . Artif Organs .2012 ;(10.111):1525-1594

18. 2012 Weng HY,Hsu MJ,Wang CC,Chen BC,Hong CY,Chen MC, Chiu WT, Lin CH. Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells . J Biomed Sci. .2012 ;(10):16-43

19. 2011 Chien, Pei-Ju,Yeh, Jiann-Horng,Chiu, Hou-Chang,Hsueh, Yu-Mei,Chen, Chien-Tsu,Chen, Mei-Chieh; Shih, Chwen-Ming. Inhibition of Peripheral Blood Natural Killer Cell Cytotoxicity in Myasthenia Gravis Patients Treated with Plasmapheresis . European Journal of Neurology .2011 ;(accep)

20. 2011 Chien PJ,Yeh JH,Chiu HC,Hsueh YM,Chen CT,Chen MC, Shih CM. Inhibition of peripheral blood natural killer cell cytotoxicity in patients with myasthenia gravis treated with plasmapheresis. . Eur J Neurol. .2011 ;(18):1350-1357

21. 2010 Hsu MJ,Chang CK,Chen MC,Chen BC,Ma HP,Hong CY, Lin CH. Apoptosis signal-regulating kinase 1 in peptidoglycan-induced COX-2 expression in macrophages. . J Leukoc Biol .2010 ;(87):1069-1082

22. 2010 Chen MC,Chen YW,Lin YC,Wu MP. Selective roles of MAPKs in regulating the post-transcriptional stability of IL-8 mRNA by CCN2 . FASEB .2010 ;(sup):0-0

23. 2009 Chen MC. NF-kappaB and AP-1 regulate RANTES expression induced by lymphotoxin beta receptor activation . The FEBS journal. .2009 ;(sup63):0-0

24. 2009 Kuo CT,Chen BC,Yu CC,Weng CM,Hsu MJ,Chen CC, Chen MC, Teng CM, Pan SL, Bien MY, Shih CH, Lin CH. Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells. . J Biomed Sci .2009 ;(16):43

25. 2009 Yu CC,Hsu MJ,Kuo ML,Chen RF,Chen MC,Bai KJ, Yu MC, Chen BC, Lin CH. Thrombin-induced connective tissue growth factor expression in human lung fibroblasts requires the ASK1/JNK/AP-1 pathway. . The Journal of Immunology .2009 ;(182):7916-7927

26. 2008 Kuo CT,Chen BC,Hsu MJ,Chen CC,Chen MC,Teng CM, Pan SL, Bien MY, Shih SH, Lin CH. Apoptosis signal-regulating kinase 1 mediates denbinobin-induced apoptosis in human lung adenocarcinoma cells . Journal of Biomedical Science .2008 ;(submit)

27. 2008 Chen MC,Liao SP,Chou MC. The Potential Roles of Oxidized Low-density Lipoprotein in Regulation of Dendritic Cell Adhesion . The FEBS journal .2008 ;(sup):0-0

28. 2007 Hsu MJ,Hsu CY,Chen BC,Chen MC,Ou George,Lin CH. ASK1 in Amyloid ß Peptide-Induced Cerebral Endothelial Cell Apoptosis . The Journal of Neuroscience .2007 ;(27):5719-5729

29. 2006 You RI,Chen MC,Wang HW,Chou YC,Hsieh SL. Inhibition of Lymphotoxin-beta Receptor (LTbR)-mediated Cell Death by Survivin-deltaEx3 . Cancer Research .2006 ;(66):3051-3061

30. 2006 Lin CH,Cheng HW,Hsu MJ,Chen MC,Lin CC,Chen BC. c-Src Mediates Thrombin-Induced NF-{kappa}B Activation and IL-8/CXCL8 Expression in Lung Epithelial Cells. . The Journal of Immunology .2006 ;(177):3427-3438

31. 2004 Chen BC,Yu CC,Lei HC,Chang MS,Hsu MJ,Huang CL, Chen MC, Sheu JR, Chen TF, Chen TL, Inou. Bradykinin B2 receptor mediates NF-kappaB activation and cyclooxygenase-2 expression via the Ras/Raf-1/ERK pathway in human airway epithelial cells . The Journal of Immunology .2004 ;(173):5219-5228

32. 2003 Chen MC, Hwang MJ, Chou YC, Chen WH, Cheng G, Nakano H, Luh TY, Mai SC, and Hsieh SL. The Role of Apoptosis Signal-regulating Kinase 1 in Lymphotoxin-beta Receptor-mediated Cell Death . The Journal of Biological Chemistry .2003 ;(278):16073-16081

33. 2002 Tsen SD, Fang SS, Chen MC, Chien JY, Lee CC, and Tsen DHL. Natural Plasmid Transformation in Escherichia coli . Journal of Biomedical Science .2002 ;(9):246-252

34. 2002 Chang YH, Hsieh SL, Chen MC, and Lin WW. Lymphotoxin-beta Receptor Induces Interleukin 8 Gene Expression via NF-kB and AP-1 Activation. . Experimental Cell Research .2002 ;(278):166-174

35. 2000 Chen MC, Hsu TL, Luh TY, and Hsieh SL. Overexpression of Bcl-2 Enhances LIGHT and Interferon-gamma-Mediated Apoptosis in Hep3BT2 Cells . The Journal of Biological Chemistry .2000 ;(275):38794-38801

36. 1999 Chang YS , Liao CL , Tsao CH, Chen MC, Liu CI, Chen LK, and Lin YL. Membrane Permeabilization by Small Hydrophobic Nonstructural Proteins of Japanese Encephalitis Virus . Journal of Virology .1999 ;(73):6257-6264

會議論文 Conference Paper


1. 2010 Chen MC,Chen YW,Lin YC,Wu MP. Selective roles of MAPKs in regulating the post-transcriptional stability of IL-8 mRNA by CCN2 . 11664 - FASEB SRC: Post-transcriptional Control of Gene Expression: Mechanisms of mRNA Decay .2010

2. 2009 Chen MC. NF-kappaB and AP-1 regulate RANTES expression induced by lymphotoxin beta receptor activation. . The FEBS journal. .2009 ;(276)

3. 2008 Chen MC,Liao SP,Chou MC. THE POTENTIAL ROLES OF OXIDIZED LOW-DENSITY LIPOPROTEIN IN REGULATION OF DENDRITIC CELL ADHESION . the FEBS journal .2008 ;(275):257

4. 2006 You RI,Chen MC,Wang HW,Chou YC,Lin CH,Hsieh SL. Inhibition of Lymphotoxin-beta Receptor (LTbR)-mediated Cell Death by Survivin-DEx3 . The Journal of Immunology (AAI Abstract Number: 541) .2006

5. 1999 Chen MC, Hsu TL, Luh TY, and Hsieh SL. LIGHT Induces Cell Apoptosis via Generation of Free Radicals and Re-localization of Bax . Programmed Cell Death at Cold Spring Harbor Laboratory .1999

6. 1999 Chen MC , and Hsieh SL. LIGHT Induces Apoptosis in Hep3BT2 Cells Overexpressing Bcl-2 . Programmed Cell Death at Cold Spring Harbor Laborator .1999

7. 1996 Chen MC, and Hsieh SL. Overexpression of Bcl-2 Enhances LIGHT/Interferon-gamma-Induced Apoptosis . The International Tumor Necrosis Factor Conference .1996

研究計畫

計畫名稱
98 ASK-1/JNK/AP-1在AMPA誘導結締組織生長因子表現與神經膠細胞增生的角色之探討
補助單位
衛生福利部雙和醫院(委託臺北醫學大學興建經營)
計畫名稱
98 AMPA/Glutamate 調控星狀神經膠細胞釋放RANTES激素之探討
補助單位
衛生福利部雙和醫院(委託臺北醫學大學興建經營)
計畫名稱
98 探討peptidoglycan誘導TLR2所媒介的發炎反應機制-Peptidoglycan作用於巨噬細胞之免疫調節功能
補助單位
行政院國家科學委員會
計畫名稱
98 Peptidoglycan作用於巨噬細胞之免疫調節功能
補助單位
臺北醫學大學
計畫名稱
97 探討peptidoglycan誘導TLR2所媒介的發炎反應機制-Peptidoglycan作用於巨噬細胞之免疫調節功能
補助單位
行政院國家科學委員會
計畫名稱
96 結締組織生長因子刺激單核球之功能鑑定
補助單位
行政院國家科學委員會
計畫名稱
96 探討peptidoglycan誘導TLR2所媒介的發炎反應機制-Peptidoglycan作用於巨噬細胞之免疫調節功能(1-3)
補助單位
行政院國家科學委員會
計畫名稱
95 乙型淋巴毒素受體在細胞激素釋放之作用機轉及功能鑑定(3-3)
補助單位
行政院國家科學委員會
計畫名稱
95 提昇私校研發能量專案計畫-探討氧化態低密度脂蛋白在中風疾病過程所扮演的病理角色-子計畫三：氧化態低密度脂蛋白影響樹突狀細胞黏附之功能分析(3-3)
補助單位
行政院國家科學委員會
計畫名稱
94 乙型淋巴毒素受體在細胞激素釋放之作用機轉及功能鑑定(2/3)
補助單位
行政院國家科學委員會
計畫名稱
94 提昇私校研發能量專案計畫-探討氧化態低密度脂蛋白在中風疾病過程所扮演的病理角色-子計畫三：氧化態低密度脂蛋白影響樹突狀細胞黏附之功能分析2/3
補助單位
行政院國家科學委員會
計畫名稱
93 乙型淋巴毒素受體在細胞激素釋放之作用機轉及功能鑑定(1/3)
補助單位
行政院國家科學委員會
計畫名稱
93 提昇私校研發能量專案計畫-探討氧化態低密度脂蛋白在中風疾病過程所扮演的病理角色-子計畫三：氧化態低密度脂蛋白影響樹突狀細胞黏附之功能分析1/3
補助單位
行政院國家科學委員會
計畫名稱
92 乙型淋巴毒素受體在人類神經細胞重要性之研究　　
補助單位
台北市立萬芳醫院委託財團法人私立臺北醫學大學辦理
計畫名稱
92 乙型淋巴毒素受體活化誘發RANTES細胞激素之訊息傳導研究
補助單位
行政院國家科學委員會
計畫名稱
92 過氧化氫刺激肺泡上皮細胞引發RANTES機制之探討
補助單位
新光醫療財團法人新光吳火獅紀念醫院
計畫名稱
92 免疫激素LIGHT引發發炎反應中RANTES分泌之機制
補助單位
臺北醫學大學專題