陳作孝(Chen, Tso-Hsiao) 教授

Email
tsohsiao@tmu.edu.tw
現   職
內科學科 教授

學經歷

學 歷

畢業學校與學位[修業時間]
臺北醫學大學臨床醫學研究所 博士
2003/09~2009/06
國立陽明醫學院醫學系 學士
1982/08~1989/06

本校學術經歷

任職單位與職稱[起迄時間]
內科學科教授
2017/08/01~
內科學科副教授
2009/08/01~2017/07/31
內科學科助理教授
2006/02/01~2009/07/31
內科學科講師
2001/08/01~2006/01/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
萬芳醫院院長
2021/02/01 ~ 2024/01/31
臨床醫學研究所助理教授
2007/08/01 ~

其它經歷

任職單位與職稱[起迄時間]
台北市立萬芳醫院主任
蘇澳榮民醫院內科主任
1998/07~1999/06
台北榮民總醫院腎臟科總醫師
1996/07~1998/06
台北榮民總醫院內科部住院醫師
1991/07~1996/06

專長與研究領域

學門領域
內科學 腎臟學
學術專長

論文著作

清冊下載


1. 2023 Exploring the Relevance between Gut Microbiota-Metabolites Profile and Chronic Kidney Disease with Distinct Pathogenic Factor . Microbiol Spectr. .2023

2. 2023 Resveratrol triggers the ER stress-mediated intrinsic apoptosis of neuroblastoma cells coupled with suppression of Rho-dependent migration and consequently prolongs mouse survival . Chem Biol Interact. .2023

3. 2022 Luminal pressure gradient and risk of arteriovenous fistula nonmaturation . Medicine .2022 ;(101):1-7

4. 2022 Chung‑Te Liu, Shih‑Chang Hsu,Hui‑Ling Hsieh, Cheng‑Hsien Chen,Chun‑You Chen,Yuh‑Mou Sue, Tso‑Hsiao Chen, Yung‑Ho Hsu, Feng‑Yen Lin, Chun‑Ming Shih, Yan‑Ting Shiu and Po‑Hsun Huang. Inhibition of β-catenin signaling attenuates arteriovenous fstula thickening in mice by suppressing myofbroblasts . Molecular Medicine .2022 ;(28):1-16

5. 2022 Chung-Yi Cheng,Shih-Hsin Hsiao,Te-Chao Fang, Yen-Chung Lin, Jude Chu-Chun Wang,Ching-Sheng Hung , Tso-Hsiao Chen, Yuh-Mou Sue. SARS-CoV2 antibody response after a third dose of heterologous ChAdOx1 nCoV-19 and Moderna vaccine in chronic dialysis patients . Journal of Infection .2022 ;(84):98-100

6. 2022 Tso-Hsiao Chen,Chung-Te Liu ,Chung-Yi Cheng ,Yuh-Mou Sue,Nai-Jen Huang,Cheng-Hsien Chen. Oligosaccharides Ameliorate Acute Kidney Injury by Alleviating Cluster of Differentiation 44-Mediated Immune Responses in Renal Tubular Cells . Nutrients .2022 ;(14):760

7. 2022 Chung-Yi Cheng,Te-Chao Fang,Hung-Wei Liao,Tso-Hsiao Chen,Jer-Hwa Chang,Yen-Chung Lin, Chih-Chin Kao, Ming-Che Liu, Hui-Wen Chang, Ching-Sheng Hung , Jude Chu-Chun Wang, Shih-Hsin Hsiao, Yuh-Mou Sue. The Humoral Immune Response of the ChAdOx1 nCoV-19 Vaccine in Maintenance Dialysis Patients without Prior COVID-19 Infection . Vaccines (Basel) . .2022 ;(10):338

8. 2022 Yun-Han Chen,Wan-Lin Liu,Tuyen Van Duong,Te-Chih Wong,Hsi-Hsien Chen,Tso-Hsiao Chen , Yung-Ho Hsu, Sheng-Jeng Peng, Shwu-Huey Yang. Effect of Different Nutritional Education Based on Healthy Eating Index for HemoDialysis Patients on Dietary Quality and Muscle Mass . Nutrients . .2022 ;(14):4617

9. 2022 Wan-Lin Liu ,Yun-Han Chen,Tuyen Van Duong , Te-Chih Wong , Hsi-Hsien Chen,Tso-Hsiao Chen, Yung-Ho Hsu , Sheng-Jeng Peng, Shwu-Huey Yang. The Effect of Different Nutritional Education Models on Reducing Cardiovascular Disease Risk Factors by Improving Dietary Fat Quality in Hemodialysis Patients . Nutrients .2022 ;(14):3840

10. 2022 Chia-Yu Chang,Jui-Tai Chen ,Tso-Hsiao Chen, Ruei-Ming Chen. Enzalutamide Induces Apoptotic Insults to Human Drug-Resistant and -Sensitive Glioblastoma Cells via an Intrinsic Bax-Mitochondrion-Cytochrome C Caspase Cascade Activation Pathway . Molecules . .2022 ;(27):66666

11. 2021 Chung-Yi Cheng,Hung-Wei Liao,Kang-Yung Peng,Tso-Hsiao Chen ,Yen-Hung Lin,Jeff S Chueh , Vin-Cent Wu. Characteristics and Outcomes in Primary Aldosteronism Patients Harboring Glucocorticoid-Remediable Aldosteronism . Biomedicines . .2021 ;(9):1816

12. 2021 Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms. . Biomedicines .2021 ;(9):343-350

13. 2021 Gut Microbiota Composition and Its Metabolites in Different Stages of Chronic Kidney Disease . J Clin Med . .2021 ;(10):1-15

14. 2021 Combined protective effects of oligo-fucoidan, fucoxanthin, and L-carnitine on the kidneys of chronic kidney disease mice . Eur J Pharmacol .2021

15. 2019 Rapidly progressive glomerulonephritis due to coexistent anti-glomerular basement membrane and anti-myeloperoxidase antibody . J Microbiol Immunol Infect. .2019

16. 2019 Duong TV,Wu PY, Wong TC,Chen HH,Chen TH,Hsu YH, Peng SJ, Kuo KL, Liu HC, Lin ET, Feng YW, Yang SH.. Mid-arm circumference, body fat, nutritional and inflammatory biomarkers, blood glucose, dialysis adequacy influence all-cause mortality in hemodialysis patients: A prospective cohort study. . Medicine (Baltimore). .2019 ;(98):1-11

17. 2019 Tang CH,Chen HH,Wu MJ,Hsu BG,Tsai JC,Kuo CC, Lin SP, Chen TH, Sue YM.. Out-of-pocket costs and productivity losses in haemodialysis and peritoneal dialysis from a patient interview survey in Taiwan. . BMJ Open .2019 ;(9):1-8

18. 2019 Chen CY,Hsu SC,Hsieh HL,Suk CW, Hsu YP,Sue YM, Chen TH, Lin FY, Shih CM, Chen JW, Lin SJ, Huang PH, Liu CT. Microbial etiology of pneumonia in patients with decreased renal function. . PLoS One .2019 ;(14):1-12

19. 2019 Duong TV,Wong TC, Chen HH,Chen TH,Hsu YH,Peng SJ, Kuo KL, Liu HC, Lin ET, Yang SH. Impact of Percent Body Fat on All-Cause Mortality among Adequate Dialysis Patients with and without Insulin Resistance: A Multi-Center Prospective Cohort Study. . Nutrients. .2019 ;(11):1-12

20. 2019 Suk CW,Hsu SC,Chen CY,Hsieh HL,Kuo HT,Hsu YP, Sue YM, Chen TH, Lin FY, Shih CM, Chen JW, Lin SJ, Huang PH, Liu CT.. Point of Care eGFR and the Prediction of Outcomes in Pneumonia. . Sci Rep. .2019 ;(9):1-9

21. 2019 Van Duong T,Tseng IH,Wong TC, Chen HH,Chen TH,Hsu YH, Peng SJ, Kuo KL, Liu HC, Lin ET, Feng YW, Yang SH.. Adaptation and Validation of Alternative Healthy Eating Index in Hemodialysis Patients (AHEI-HD) and Its Association with all-Cause Mortality: A Multi-Center Follow-Up Study. . Nutrients. .2019 ;(11):1-15

22. 2019 Wang CS,Wong TC,Duong TV,Su CT,Chen HH,Chen TH, Hsu YH, Peng SJ, Kuo KL, Liu HC, Lin ET, Feng YW, Yang SH.. Hyperhomocysteinemia Associated with Low Muscle Mass, Muscle Function in Elderly Hemodialysis Patients: An Analysis of Multiple Dialysis Centers. . Biomed Res Int. .2019

23. 2019 Duong TV,Shih CK,Wong TC,Chen HH,Chen TH,Hsu YH, Peng SJ, Kuo KL, Liu HC, Lin ET, Su CT, Yang SH.. Insulin Resistance and Cardiovascular Risks in Different Groups of Hemodialysis Patients: A Multicenter Study. . Biomed Res Int. .2019

24. 2018 Double filtration plasmapheresis in treatment of acute pancreatitis associated with severe hypertriglyceridemia: Three case reports. . Medicine (Baltimore). .2018 ;(97):e12987

25. 2018 Inadequate dietary energy intake associates with higher prevalence of metabolic syndrome in different groups of hemodialysis patients: a clinical observational study in multiple dialysis centers. . BMC Nephrol .2018 ;(19):236

26. 2018 Associations of dietary macronutrients and micronutrients with the traditional and nontraditional risk factors for cardiovascular disease among hemodialysis patients: A clinical cross-sectional study. . Medicine (Baltimore) .2018 ;(97):e11306

27. 2018 Alleviative effect of fucoxanthin-containing extract from brown seaweed Laminaria japonica on renal tubular cell apoptosis through upregulating Na+/H+ exchanger NHE1 in chronic kidney disease mice. . J Ethnopharmacol. .2018 ;(224):391-399

28. 2018 The cut-off values of dietary energy intake for determining metabolic syndrome in hemodialysis patients: A clinical cross-sectional study. . PLoS One .2018 ;(13):e0193742

29. 2017 Chen CH,Sue YM,Cheng CY,Chen YC,Liu CT,Hsu YH, Hwang PA, Huang NJ, Chen TH*. Oligo-fucoidan prevents renal tubulointerstitial fibrosis by inhibiting the CD44 signal pathway . Sci Rep. .2017 ;(7):.-.

30. 2017 The novel compound MP407 inhibits platelet aggregation through cyclic AMP-dependent processes . Eur J Pharmacol .2017 ;(815):324-331

31. 2017 Fucoidan ameliorates pancreatic β-cell death and impaired insulin synthesis in streptozotocin-treated β cells and mice via a Sirt-1-dependent manner . Mol Nutr Food Res. .2017 ;(61)

32. 2017 Economic costs of automated and continuous ambulatory peritoneal dialysis in Taiwan: a combined survey and retrospective cohort analysis . BMJ Open .2017 ;(7):e015067

33. 2017 Far-infrared protects vascular endothelial cells from advanced glycation end products-induced injury via PLZF-mediated autophagy in diabetic mice . Sci Rep .2017 ;(7):40442-4054

34. 2017 Pioglitazone and cardiovascular outcomes in patients with insulin resistance, pre-diabetes and type 2 diabetes: a systematic review and meta-analysis . BMJ Open .2017 ;(7):e013927

35. 2016 Peroxisome proliferator-activated receptor alpha protects renal tubular cells from gentamicin-induced apoptosis via up-regulating Na+/H+ exchanger NHE1 . Mol Med .2016 ;(21):886-889

36. 2016 Tang CH,Wang CC,Chen TH,Hong CY,Sue YM. Prognostic Benefits of Carvedilol, Bisoprolol, and Metoprolol Contrclledb Release/Extended Release in Hemodilaysis patients with Heart Failure: A 10-Year Cohort . J Am Heart Assoc. .2016 ;(5):1-11

37. 2016 Wong TC,Chen YT,Wu PY,Chen TW,Chen HH,Chen TH, Hsu YH, Yang SH. Ratio of diety w-3 and w-6 fatty acids-independent determinants of muscle mass in hemodialysis patients with diabetes . Nutrition .2016 ;(32):989-994

38. 2016 Tang CH,Chen TH,Fan TC,Huang SY,Huang KC,Wu YT, Wang CC, Sue YM. Do Automated peritoneal Dialysis and Continuous Ambulatory Peritoneal Dialysis Have the Same Clinical Outcomes ? A Ten-year Cohort Study in Taiwan . Sci Rep .2016 ;(6):1-11

39. 2016 Wong TC,Su HY,Chen YT,Wu PY,Chen HH,Chen TH, Hsu YH, Yang SH. Ratio of C-Reactive Protein to Albumin Predicts Muscle Mass in Adult Patient Undergoing Hemodialysis . PLoS One .2016 ;(11):e01654

40. 2015 Lu SH,Chen TH,Chou TC. Magnolol Inhibits RANKL-induced osteoclast differentiation of raw 264.7 macrophages through heme oxygenase-1-dependent inhibition of NFATc1 expression . J Nat Prod .2015 ;(78):61-68

41. 2015 Tsai SH,Wang MY,Miao NF,Chian PC,Chen TH,Tsai PS. CE: original research: The efficacy of a nurse-led breathing training program in reducing depressive symptoms in patients on hemodialysis: a randomized controlled trial. . Am J Nurs .2015 ;(115):24-32

42. 2015 Chen TH,Shih CY,Hsu WL,Chou TC. Mechanisms of Nifedipine-Downregulated CD40L/sCD40L Signaling in Collagen Stimulated Human Platelets. . PLoS One .2015 ;(10):1-15

43. 2015 Lin MH,Chen MC,Chen TH,Chang HY,Chou TC. Magnolol ameliorates lipopolysaccharide-induced acute lung injury in rats through PPAR-γ-dependent inhibition of NF-kB activation. . Int Immunopharmacol .2015 ;(28):270-278

44. 2015 Wong TC,Chen YT,Wu PY,Chen TW,Chen HH,Chen TH, Yang SH. Ratio of Dietary n-6/n-3 Polyunsaturated Fatty Acids Independently Related to Muscle Mass Decline in Hemodialysis Patients. . PLoS One .2015 ;(10):e01404

45. 2015 Wu PY,Yang SH,Wong TC,Chen TW,Chen HH,Chen TH, Chen YT.. Association of Processed Meat Intake with Hypertension Risk in Hemodialysis Patients: A Cross-Sectional Study. . PLoS One .2015 ;(10):e01419

46. 2015 Cheng CY,Huang PJ,Chen TH. A Patient with Encapsulating Peritoneal Sclerosis Complicated with Hepatic Portal Venous Gas Who Survives Conservative Treatment. . Perit Dial Int .2015 ;(35):605-606

47. 2015 Lu SH,Hsu WL,Chen TH,Chou TC. Activation of Nrf2/HO-1signaling pathway involves the anti-inflammatory activity of magnolol in Porphyromonas gingivalis lipopolysaccharide-stimulated mouse RAW 264.7 macrophages. . Int Immunopharmacol. .2015 ;(29):770-778

48. 2014 Chen CH,Cheng CY,Chen YC,Sue YM,Liu CT,Chen TH. MicroRNA-328 inhibits renal tubular cell epithelial-to-mesenchymal transition by targeting the CD44 in pressure-induced renal fibrosis . PLoS One .2014 ;(9):1-10

49. 2014 Lee CY,Tsai YT,Loh SH,Liu JC,Chen TH,Chao HH, Cheng TH, Chen JJ. Urotensin II induces interleukin 8 expression in human umbilical vein endothelial cells . PLoS One .2014 ;(9):e90278

50. 2014 Chiu YF,Chen YC,Wu PY,Shih CK,Chen HH,Chen HH, Chen TH, Yang SH. Association between the hemodialysis eating index and risk factors of cardiovascular disease in hemodialysis patients. . J Ren Nutr .2014 ;(24):163-171

51. 2014 Hsu YH,Chen TH,Wu MY,Lin YF,Chen WL,Cheng TH, Chen CH.. Protective effects of Zhibai Dihuang Wan on renal tubular cells affected with gentamicin-induced apoptosis . J Ethnopharmacol .2014 ;(151):635-642

52. 2014 Chen KJ,Chen TH,Sue YM,Chen TJ,Cheng CY. High-volume plasma exchange in a patient with acute liver failure due to non-exertional heat stroke in a sauna . J Clin Apher .2014 ;(29):281-283

53. 2013 Liu CT,Chen TH,Cheng CY. Successful treatment of drug-induced acute liver failure with high-volume plasma exchange. . J Clin Apher .2013 ;(28):430-434

54. 2013 Wang KY,Wang CC,Cheng CY,Chen YC,Chen TH,Sue YM. The case: hexadactyly, blindness, obesity, and end-stage renal disease. . Kidney Int .2013 ;(84):1291-1292

55. 2013 Chen TH,Kuro-O M,Chen CH,Sue YM,Chen YC,Wu HH, Cheng CY. The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice . Eur J Pharmacol .2013 ;(698):67-73

56. 2013 Chen CH,Cheng CY,Chen YC,Sue YM,Hsu YH,Tsai WL, Chen TH. Rosuvastatin inhibits pressure-induced fibrotic responses via the expression regulation of prostacyclin and prostaglandin E2 in rat renal tubular cells. . European Journal of Pharmacology .2013 ;(700):65-73

57. 2013 Wang MY,Chan SF,Chang LI,Chen TH,Tsai PS. Better sleep quality in chronic haemodialyzed patients is associated with morning-shift dialysis: A cross-sectional observational study . Int J Nurs Stud .2013 ;(50):1468-1473

58. 2013 Cherng YG,Liao CC,Chen TH,Xiao D,Wu CH,Chen TL. Are non-cardiac surgeries safe for dialysis patients? - A population-based retrospective cohort study . PLoS One .2013 ;(8):e58942

59. 2013 Tang CH,Chen TH,Wang CC,Hong CY,Huang KC,Sue YM. Renin-angiotensin system blockade in heart failure patients on long-term haemodialysis in Taiwan . Eur J Heart Fail .2013 ;(15):1194-1202

60. 2013 Hsu YH,Chen TH,Chen YC,Cheng CY,Sue YM,Chen JR, Chen CH. Urotensin II exerts antiapoptotic effect on NRK-52E cells through prostacyclin-mediated peroxisome proliferator-activated receptor alpha and Akt activation . Mol Cell Endocrinol .2013 ;(5):168-174

61. 2013 Chen KJ,Chen TH,Sue YM. Citrobacter youngae and Pantoea agglomerans peritonitis in a peritoneal dialysis patient . Perit Dial Int .2013 ;(33):336-337

62. 2012 Liu CT,Chen YC,Chen TH,Barghouth U,Fan CK. Intestinal paragonimiasis with colonic ulcer and hematochezia in an elderly taiwanese woman . Korean J Parasitol .2012 ;(50):349-352

63. 2012 Hsu YH,Chen YC,Chen TH,Sue YM,Cheng TH,Chen JR, Chen CH. Far-infrared therapy induces the nuclear translocation of PLZF which inhibits VEGF-induced proliferation in human umbilical vein endothelial cells. . PLoS One .2012 ;(7):e30674

64. 2012 Liu CT,Chen YC,Chen TH,Ou TY. Necrotizing fasciitis of thigh associated with Escherichia Coli bacteremia in a patient on chronic hemodialysis . Hemodial Int .2012 ;(16):564-567

65. 2012 Hsu YH,Cheng CY,Chen YC,Chen TH,Sue YM,Tsai WL, Chen CH. Long-term leptin treatment exerts a pro-apoptotic effect on renal tubular cells via prostaglandin E2 augmentation . Eur J Pharmacol .2012 ;(689):65-71

66. 2012 Chan SF,Chen TH,Liao YM,Chou KR,Tsai PS. Development and preliminary validation of the Chinese version of the Sleep-Associated Monitoring Index . Int J Nurs Stud .2012 ;(49):54-64

67. 2011 Shen WC,Chiang YC,Chen HY,Chen TH,Yu FL,Tang CH, Sue YM. Nephrotoxicity of vancomycin in patients with methicillin-resistant Staphylococcus aureus bacteraemia . Nephrology .2011 ;(16):697-703

68. 2011 Chen YC,Chen CH,Ko WS,Cheng CY,Sue YM,Chen TH. Dipyridamole inhibits lipopolysaccharide-induced cyclooxygenase-2 and monocyte chemoattractant protein-1 via heme oxygenase-1-mediated reactive oxygen species reduction in rat mesangial cells. . Eur J Pharmacol .2011 ;(10):445-450

69. 2011 Yen-Cheng Chena,Cheng-Hsien Chen,Yung-Ho Hsu,Tso-Hsiao Chen,Yuh-Mou Sue,Chung-Yi Chenga , Tzen-Wen Chen. Leptin reduces gentamicin-induced apoptosis in rat renal tubular cells via the PI3K-Akt signaling pathway . Eur J Pharmacol .2011 ;(658):213-218

70. 2011 Yen-Chung Lin,Yen-Cheng Chen,Tso-Hsiao Chen,Hsi-Hsien Chen,Wei-Jen Tsai. Acute Kidney Injury Associated with Hepato-protective Chinese Herb e Pien Tze Huang . Journal of Experimental and Clinical Medicine .2011 ;(3):184-186

71. 2010 Hsu YH,Lin WL,Hou YT,Pu YS,Shun CT,Chen CL, Wu YY, Chen JY, Chen TH, Jou TS. Podocalyxin EBP50 ezrin molecular complex enhances the metastatic potential of renal cell carcinoma through recruiting Rac1 guanine nucleotide exchange factor ARHGEF7. . Am J Pathol .2010 ;(176):3050-3061

72. 2009 Fan YC,Cheng CY,Chen CH,Chen TW,Chen TH. Dipyridamole Inhibits Lipopolysaccharide-Induced Interleukin-6 Secretion via Activation of Mitogen-Activated Protein Kinase Phosphatase-1 in Rat Mesangial Cells . Acta Nephrologica .2009 ;(23):33-39

73. 2009 Hung SY,Liou HH,Ger LP,Chen LK,Liu MC,Chung HM, Chou KJ, Chen TH, Lin CK, Yang Y. Clustering of Unconventional Cardiovascular Risk Factors among Taiwanese Hemodialysis Patients . Am J Nephrol .2009 ;(30):222-231

74. 2009 Chen TH,Chang CF,Yu SC,Wang JC,Chen CH,Chan P, Lee HM. Dipyridamole inhibits cobalt chloride-induced osteopontin expression in NRK52E cells . Eur J Pharmacol .2009 ;(613):10-18

75. 2009 Sue YM,Chen CH,Hsu YH,Hou CC,Cheng CY,Chen YC, Lin SL, Chen TW, Chen TH. Urotensin II induces transactivation of the epidermal growth factor receptor via transient oxidation of SHP-2 in the rat renal tubular cell line NRK-52E . Growth Factors .2009 ;(27):155-162

76. 2009 Chen HH,Sue YM,Chen CH,Hsu YH,Hou CC,Cheng CY, Lin SL, Tsai WL, Chen TW, Chen TH. Peroxisome proliferator-activated receptor alpha plays a crucial role in L-carnitine anti-apoptosis effect in renal tubular cells . Nephrol Dial Transplant .2009 ;(24):3042-3049

77. 2008 Hsu YH,Chen CH,Hou Cc,Sue YM,Cheng CY,Lin H, Tsai WL, Chan P, Chen TH. Prostacyclin protects renal tubular cells from gentamicin-induced apoptosis via a PPARalpha-dependent pathway . kidney International .2008 ;(73):578-587

78. 2008 Lin YL,Fan YC,Cheng CY,Sue YM,Hsu YH,Hou CC, Chen TH, Chen TW. The case | Sterile pyuria and an abnormal abdominal film. "Autonephrectomy" of right kidney. . Kidney International .2008 ;(73):131-133

79. 2007 Yang HY,Kao PF,Chen TH,Tomlinson B,Kp WC,Chan P. Effects of the Angiotensin II Type 1 Receptor Antagonist Valsartan on the Expression of Superoxide Dismutase in Hypertensive Patients . J Clin Pharmacol .2007 ;(47):397-403

80. 2007 Juan SH,Chen CH,Hsu YH,Hou CC,Chen TH,Lin H, Chu YL. Sue YM. Tetramethylpyrazine protects rat renal tubular cell apoptosis induced by gentamicin. . Nephrol Dial Transplant .2007 ;(22):732-9

81. 2007 Chen TH,Hsu YT,Chen CH,Kao SH,Lee HM. Tanshinone IIA from Salvia miltiorrhiza induces heme oxygenase-1 expression and inhibits lipopolysaccharide-induced nitric oxide expression in RAW 264.7 cells . Mitochondrion .2007 ;(7):101-105

82. 2006 Chen CH,Lin H,Hsu YH,Sue YM,Cheng TH,Chan P, Chen TH. The protective effect of prostacyclin on adriamycin-induced apoptosis in rat renal tubular cells . Eur J Pharmacol .2006 ;(4):8-15

83. 2006 Chen TH,Kao YC,Chen BC,Chen CH,Chan P,Lee HM. Dipyridamole activation of mitogen-activated protein kinase phosphatase-1 mediates inhibition of lipopolysaccharide-induced cyclooxygenase-2 expression in RAW 264.7 cells . Eur J Pharmacol .2006 ;(541):138-146

84. 2006 Chen CH,Hsu YH,Sue YM,Hou CC,Lee HM,Huang HM, Chen TH. Src homology 2-containing phosphotyrosine phosphatase regulates endothelin-1-induced epidermal growth factor receptor transactivation in rat renal tubular cell NRK-52E. . Pflugers Arch .2006 ;(452):16-24

85. 2005 Chen TH,Chen SC,Chan P,Chu YL,Yang HY,Cheng JT. Mechanism of the hypoglycemic effect of stevioside, a glycoside of stevia rebaudiana . Planta Medica .2005 ;(71):108-113

86. 2005 Chen TH,Chang PC,Chang MC,Lin YF,Lee HM. Chloroquine induces the expression of inducible nitric oxide synthase in C6 glioma cells . Pharmacological Research .2005 ;(51):329-336

87. 2005 Liao HW,Lin KH,Chen TH,Wang CC,Sue YM. Penile gangrene in a chronic dialysis patient. . Nephrol Dial Transplant. .2005 ;(20):1503-1504

88. 2005 Chen TH,Wang JF,Chan P,Lee HM. Angiotensin II Stimulates Hypoxia-Inducible Factor 1{alpha} Accumulation in Glomerular Mesangial Cells. . Ann N Y Acad Sci. .2005 ;(1042):286-93

89. 2005 Hou CC,Hung SC,Kao SH,Chen TH,Lee HM. Celecoxib induces heme-oxygenase expression in glomerular mesangial cells . Ann N Y Acad Sci. .2005 ;(1042):235-245

90. 2005 Hou CC,Wang W,Huang XR,Fu P,Chen TH,Sheikh-Hamad D, Lan HY. Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney . Am J Pathol .2005 ;(166):761-771

91. 2005 Liao HW,Chen TH,Lin KH,Lin HH,Hsu YH,Hou CC, Sue YM. Emphysematous pyelonephritis caused by Bacteroides fragilis . Nephrology Dialysis Transplantation .2005 ;(20):2575-2577

92. 2004 Juan SH,Chen JJ,Chen CH,Lin H,Cheng CF,Liu JC, Hsieh MH, Chen YL, Chao HH, Chen TH, Chan. The 17beta-estradiol injibits cyclic strain-induced endothelin-1 gene expression within vascular endothelial cells . Am J Physiol Heart Circ Physiol .2004 ;(287):H1254-1261

93. 2004 Chang PC,Chen TH,Chang CJ,Hou CC,Chan P,Lee HM. Advanced glycosylation end products induce inducible nitric oxide synthase (iNOS) expression via a p38 MAPK-dependent pathway. . Kidney Int. .2004 ;(65):1664-1675

94. 2004 Hsu YH,Chen JJ,Chang NC,Chen CH,Liu JC,Chen TH, Jeng CJ, Chao HH, Cheng TH.. Role of reactive oxygen species-sensitive extracellular signal-regulated kinase pathway in angiotensin II-induced endothelin-1 gene expression in vascular endothelial cells . J Vasc Res. 2004 Jan-Feb;41(1):64-74. Epub 2004 Jan 16 .2004 ;(41):64-74

95. 2003 Chu YC,Chen JD,Cheng CY,Chen HH,Hsu YH,Chen TH, Chen PY. Poor Outcome of Antibiotic-Lock Technique for Therapy of Hemodialysis Catheter Related Staphylococcus Aureus Bacteremia . Acta Nephrologica .2003 ;(17):76-80

96. 2003 Chen TH,Chen YJ,Hsu YH,Sue YM,Hou CC,Lee HM. Dipyridamole induces apoptosis by inhibiting Akt activation in rat mesangial cells . Acta Nephrologica .2003 ;(17):57-62

97. 2001 Tso-Hsiao Chen, Ju-Chi Liu, Jun-Jen Chang, min-Fung Tsai, Ming-Hsiung Hsieh, Paul Chan. The in Vitro Inhibitory Effect of Flavonoid Astilbin on 3-Hydroxyl-3-Methylglutaryl Coenzyme A reductase on verb Cells . Chinese Medical Journal (Taipei) .2001 ;(64):382-387

98. 2001 Min-Feng Tsai, Tso-Hsiao Chen, Ju-Chi Liu, Yi-Jen Chen, Min-Hsiung Hsieh, Paul Chan. Effect of Tetramethylpyrazine on Blood Pressure in Hypertensive Rats and Calcium Mobilization in Vascular Smooth Muscle Cells. . Acta Cardiol Sin .2001 ;(17):3-8

99. 2001 Jun-Jen Chang, Tso-Hsiao Chen, Paul Chan, Yi-Jen Chen, Feng-Lin Hsu, Ming-Yu Lo, Jung-Yaw Lin. The in Vitro Inhibitory Effect of Tannin Derivates on 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase on Verb Cells . Pharmacology .2001 ;(62):224-228

100. 1996 Tso-Hsiao Chen, Tzen-Wen Chen, Tung-Po Huang. The Serial Biochemical Changes in End Stage Renal Disease Patients Undergoing CAPD:Ten-Year Experience . J Nephrology ROC .1996 ;(9):150-157

研究計畫

計畫名稱
110 建置轉譯導向婦癌生醫巨量資料庫開發精準醫療輔助系統(2/4)
補助單位
國家科學及技術委員會

計畫名稱
109 寡糖經由調節發炎反應來保護急性腎損傷的機制研究
補助單位
科技部

計畫名稱
109 建置轉譯導向婦癌生醫巨量資料庫開發精準醫療輔助系統(1/4)
補助單位
科技部

計畫名稱
107 藻褐(Laminaria japonica)酒精萃取物對慢性腎病變的保護作用及其分子機制的探討
補助單位
科技部

計畫名稱
104 褐藻多醣硫酸酯對腎臟纖維化的抑制作用
補助單位
科技部

計畫名稱
101 MicroRNA參與壓力引發腎臟纖維化早期機制之研究
補助單位
行政院國家科學委員會

計畫名稱
100 施德丁抑制大鼠腎小管細胞經壓力所誘導細胞凋亡與腎間質纖維化
補助單位
行政院國家科學委員會

計畫名稱
99 施德丁抑制大鼠腎小管細胞經壓力所誘導細胞凋亡與腎間質纖維化
補助單位
行政院國家科學委員會

計畫名稱
98 施德丁抑制大鼠腎小管細胞經壓力所誘導細胞凋亡與腎間質纖維化
補助單位
行政院國家科學委員會

計畫名稱
97 Dipyridamole抑制大鼠NRK-52E腎小管細胞骨橋素的表現與單側輸尿管結紮後腎間質纖維化(2-2)
補助單位
行政院國家科學委員會

計畫名稱
96 Dipyridamole抑制大鼠NRK-52E腎小管細胞骨橋素的表現與單側輸尿管結紮後腎間質纖維化(1-2)
補助單位
行政院國家科學委員會

計畫名稱
95 在NRK49F腎臟間質纖維母細胞中丹參酮 IIA抑制高濃度葡萄糖所誘導骨橋素表現的機制
補助單位
行政院國家科學委員會

計畫名稱
95 Urotensin II在大鼠腎小管細胞中訊號傳遞路徑之研究:過氧化物增生與表皮生長因子受器之轉活化之關聯機制
補助單位
臺北醫學大學新聘教師計畫

計畫名稱
94 鼠尾草屬植物 的丹參酮 IIA能誘導血紅素氧合酶-1 的表現與在巨噬細胞中抑制細菌脂多糖所誘導環氧脢-2 的表現與心律不整作用
補助單位
行政院國家科學委員會