蔡若婷(Tsai, Jo-Ting) 教授

Email
kitty@tmu.edu.tw
現   職
放射線學科 教授

學經歷

學 歷

畢業學校與學位[修業時間]
國立陽明大學醫學工程 博士
2000/10/01~2009/06/30
台北醫學院醫學系 學士
1985/10~1992/06

本校學術經歷

任職單位與職稱[起迄時間]
放射線學科教授
2021/02/01~
放射線學科副教授
2014/08/01~2021/01/31
放射線學科助理教授
2008/08/01~2014/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
臨床醫學研究所教授
2024/07/01 ~

其它經歷

任職單位與職稱[起迄時間]
國家衛生研究院顱內腫瘤研究委員會委員
2001/05~2003/06
萬芳醫學中心癌症品質管理委員會執行長
2000/01~2008/12
萬芳醫院放射腫瘤科光子刀中心主任
台北醫學院附設醫院兼任主治醫師
台北馬偕醫院放射腫瘤科主治醫師
1996/08~1998/04
台北馬偕醫院放射腫瘤科總醫師
1995/08~1996/07
台北馬偕紀念醫院放射腫瘤科住院醫師
1992/02~1995/07

專長與研究領域

學門領域
放射線及核子醫學
醫用電子
學術專長

論文著作

清冊下載


1. 2024 Po‑Wei Huang,Syu‑Jyun Peng,David Hung‑Chi Pan,Huai‑CheYang, Jo‑TingTsai,Cheng‑Ying Shiau. Vascular compactness of unruptured brain arteriovenous malformation predicts risk of hemorrhage after stereotactic radiosurgery . Scientifc Reports .2024

2. 2023 Hsin-Lun Lee,Yi-Chieh Tsai,Narpati Wesa Pikatan,Chi-Tai Yeh,Vijesh Kumar Yadav, Ming-Yao Chen ( Jo-Ting Tsai). Tumor-Associated Macrophages Affect the Tumor Microenvironment and Radioresistance via the Upregulation of CXCL6/CXCR2 in Hepatocellular Carcinoma . biomedicines .2023 ;(11)

3. 2023 Hsin-Lun Lee,Yao Chen Chuang,Jo-Ting Tsai,Yu-Chen Chen,Ping-Hsiu Wu,Yao-An Shen. Gold Nanodandelions as Nanozymes and Reactive Oxygen Species Scavengers in Tumor Microenvironment Components . ACS Appl. Nano Mater. .2023 ;(6):21359-21370

4. 2023 Chin-Beng Ho, Jo-Ting Tsai,Chun-You Chen, Her-Shyong Shiah,Hsuan-Yu Chen, Jeng-Fong Chiou. Effectiveness of Stereotactic Ablative Radiotherapy for Systemic Therapy Respondents with Inoperable Pulmonary Oligometastases and Oligoprogression . Diagnostics .2023 ;(13):1597

5. 2022 Sheng-Fang Huang,Hao-Wen Cheng,Jo-Ting Tsai,Chun-Yuan Kuo,Chih-Chieh Chang,Ming-Hsien Li. Failure mode and effects analysis for errors detected during pretreatment physics plan and chart review in external beam radiotherapy. . Ther Radiol Oncol .2022 ;(6):1-10

6. 2022 Jang-Chun Lin,Yi-Chieh Wu ,Fu-Chi Yang ,Jo-Ting Tsai ,David YC Huang , Wei-Hsiu Liu . Genome-Wide Association Study Identifies Multiple Susceptibility Loci for Malignant Neoplasms of the Brain in Taiwan. . J. Pers. Med. .2022 ;(12):2-14

7. 2022 Ruo-Zhu Tai ,El-Wui Loh ,Jo-Ting Tsai ,Ka-Wai Tam. Effect of hyaluronic acid on radiotherapy-induced mucocutaneous side effects: a meta-analysis of randomized controlled trials . Support Care Cancer .2022 ;(30):4845-4855

8. 2022 Po-Wei Huang,Syu-Jyun Peng,David Hung-Chi Pan, Huai-Che Yang ,Jo-Ting Tsai,Cheng-Chia Lee. Compactness index: a radiosurgery outcome predictor for patients with unruptured brain arteriovenous malformations . J Neurosurg .2022 ;(138):241-250

9. 2022 Chun-Yuan Kuo ,Wei-Hsiu Liu,Yu-Ching Chou,Ming-Hsien Li,Jo-Ting Tsai ,Jang-Chun Lin. To Optimize Radiotherapeutic Plans for Superior Tumor Coverage Predicts Malignant Glioma Prognosis and Normal Tissue Complication Probability. . J. Clin. Med. .2022 ;(11):1-14

10. 2022 Ming-Hsien Li,Li-Jhen Chen,Chih-Chieh Chang,Jo-Ting Tsai,Jang-Chun Lin. Effect of the simulated half leaf width of a multileaf collimator on volumetric modulated arc therapy plan quality in hippocampal avoidance whole-brain radiotherapy . J Appl Clin Med Phys .2022

11. 2021 Pai ,Yadav VK, Kuo KT,Pikatan NW,Lin CS,Chien MH, Lee WH, Hsiao M, Chiu SC, Yeh CT, Tsai JT . PDK1 Inhibitor BX795 Improves Cisplatin and Radio-Efficacy in Oral Squamous Cell Carcinoma by Downregulating the PDK1/CD47/Akt-Mediated Glycolysis Signaling Pathway. . International Journal of Molecular Sciences .2021 ;(22):;22(21):11492

12. 2021 Impact of respiratory motion in dosimetric and clinical advantages for adjuvant left-sided breast radiotherapy. . Journal of Radiation Research .2021 ;(62):1105-1113

13. 2020 Optimal tumor coverage with different beam energies by IMRT, VMAT and TOMO: Effects on patients with proximal gastric cancer. . Medicine (Baltimore) .2020 ;(99):23328.

14. 2020 Dosimetric comparison of helical tomotherapy, volumetric-modulated arc therapy, intensity-modulated radiotherapy, and field-in-field technique for synchronous bilateral breast cancer. . Medical Dosimetry .2020 ;(45):271-277

15. 2020 Liu WH,Lin JC, Chou YC,Li MH,Tsai JT. CD44-associated radioresistance of glioblastoma in irradiated brain areas with optimal tumor coverage . Cancer Med. .2020 ;(9):350-360

16. 2020 Oluwaseun Adebayo Bamodu,Hang-Lung Chang ,Jiann-Ruey Ong,Wei-Hwa Lee, Chi-Tai Yeh, Jo-Ting Tsai. Elevated PDK1 Expression Drives PI3K/AKT/MTOR Signaling Promotes Radiation-Resistant and Dedifferentiated Phenotype of Hepatocellular Carcinoma. . Cells .2020 ;(9)

17. 2020 Targeting the Epigenetic Non-Coding RNA MALAT1/Wnt Signaling Axis as a Therapeutic Approach to Suppress Stemness and Metastasis in Hepatocellular Carcinoma. . cells .2020

18. 2019 Pai S,Bamodu OA, Lin YK,Lin CS,Chu PY, Yeh CT , Tsai JT. CD47-SIRPα Signaling Induces Epithelial-Mesenchymal Transition and Cancer Stemness and Links to a Poor Prognosis in Patients with Oral Squamous Cell Carcinoma . Cells .2019 ;(8)

19. 2019 Lee HL,Tsai JT,Chen CY,Lin YC,Ho CB,Chiou JF. Effectiveness of stereotactic ablative radiotherapy in patients with advanced hepatocellular carcinoma unsuitable for transarterial chemoembolization. . Ther Adv Med Oncol .2019 ;(11)

20. 2019 Karnofsky Performance Status as A Predictive Factor for Cancer-Related Fatigue Treatment with Astragalus Polysaccharides (PG2) Injection-A Double Blind, Multi-Center, Randomized Phase IV Study . Cancers .2019 ;(11):128

21. 2019 MSI1 associates glioblastoma radioresistance via homologous recombination repair, tumor invasion and cancer stem-like cell properties . Radiother Oncol. .2019 ;(129):352-363

22. 2019 Lin JC,Tsai JT,Chao TY,Ma HI, Liu WH. Musashi-1 Enhances Glioblastoma Migration by Promoting ICAM1 Translation . Neoplasia .2019 ;(21):459-468

23. 2019 Huang WC ,Kuo KT,Bamodu OA,Lin YK,Wang CH,Yeh CT*, Tsai JT*. Astragalus polysaccharide (PG2) Ameliorates Cancer Symptom Clusters, as well as Improves Quality of Life in Patients with Metastatic Disease, through Modulation of the Inflammatory Cascade . Cancers .2019 ;(11)

24. 2019 Tsai YC, Lee HL,Kuo CC,Chen CY,Hsieh KL,Tsai JT*, Chiou JF*. Prognostic and predictive factors for clinical and radiographic responses in patients with painful bone metastasis treated with magnetic resonance-guided focused ultrasound surgery . Int J Hyperthermia .2019 ;(36):932-937

25. 2019 Bamodu OA, Kuo KT,Wang CH, Huang WC,Wu ATH,Tsai JT. Astragalus polysaccharides (PG2) Enhances the M1 Polarization of Macrophages, Functional Maturation of Dendritic Cells, and T Cell-Mediated Anticancer Immune Responses in Patients with Lung Cancer . Nutrients 2019 Sep 20;11(10). .2019 ;(11)

26. 2018 Ovatodiolide suppresses yes-associated protein 1-modulated cancer stem cell phenotypes in highly malignant hepatocellular carcinoma and sensitizes cancer cells to chemotherapy in vitro . Toxicology in Vitro .2018 ;(51):74-82

27. 2018 Ovatodiolide suppresses nasopharyngeal cancer by targeting stem cell-like population, inducing apoptosis, inhibiting EMT and dysregulating JAK/STAT signaling pathway . Phytomedicine .2018 ;(56):269-278

28. 2018 Compared with intensity-modulated radiotherapy, image-guided radiotherapy reduces severity of acute radiation-induced skin toxicity during radiotherapy in patients with breast cancer . Cancer Medicine .2018 ;(7):3622-3629

29. 2018 Downregulation of Cancer Stemness by Novel Diterpenoid Ovatodiolide Inhibits Hepatic Cancer Stem Cell-Like Traits by Repressing Wnt/β-Catenin Signaling . Am J Chin Med. .2018 ;(46):891-910

30. 2018 The STAT3/Slug Axis Enhances Radiation-Induced Tumor Invasion and Cancer Stem-like Properties in Radioresistant Glioblastoma . cancers .2018 ;(10)

31. 2018 Variations in dosimetric distribution and plan complexity with collimator angles in hypofractionated volumetric arc radiotherapy for treating prostate cancer. . J Appl Clin Med Phys. .2018

32. 2018 Piperlongumine inhibits cancer stem cell properties and regulates multiple malignant phenotypes in oral cancer . Oncol Lett .2018 ;(15):1789-1798

33. 2018 Gamma Knife Perfexion® radiosurgery and endo diode laser thermotherapy for choroidal melanoma with technical analysis: A case report. . Oncol Lett. .2018 ;(15):91-98

34. 2018 Comparison of Thoracic Radiotherapy Efficacy Between Patients With and Without EGFR-mutated Lung Adenocarcinoma. . In Vivo .2018 ;(32):203-209

35. 2017 Feasibility Study on Applying Radiophotoluminescent Glass Dosimeters for CyberKnife SRS Dose Verification . PLoS One. .2017 ;(12)

36. 2017 Dosimetric and radiobiological comparison of Cyberknife and Tomotherapy in stereotactic body radiotherapy for localized prostate cancer . Journal of X-Ray Science and Technology .2017 ;(25):465-477

37. 2017 Magnetic Resonance-Guided Focused Ultrasound Versus Conventional Radiation Therapy for Painful Bone Metastasis . J Bone Joint Surg Am. .2017 ;(99):1572-1578

38. 2017 Evaluation of Clinical Application and Dosimetric Comparison of Treatment Plans of Gamma Knife and CyberKnife in Treating Arteriovenous Malformations . Stereotact Funct Neurosurg. .2017 ;(95):142-148

39. 2017 Jang-Chun Lin,Jo-Ting Tsai,Ming-Ying Liu,Chi-Tun Tang,Ming-Hsien Li,Wei-Hsiu Liu. Unusual Presentations of Intracranial Solitary Fibrous Tumor with Malignant Transformation . anatomy & physiology .2017

40. 2017 Lin JC,Tsai JT,Chen LJ,Li MH,Liu WH. Compared planning dosimetry of TOMO, VMAT and IMRT in rectal cancer with different simulated positions . Oncotarget .2017

41. 2017 Forward treatment planning techniques to reduce the normalization effect in Gamma Knife radiosurgery . J Appl Clin Med Phys. .2017 ;(18(6)):114-122

42. 2016 Recommendation for axillary lymph node dissection in women with early breast cancer and sentinel node metastasis: A systematic review and meta-analysis of randomized controlled trials using the GRADE system. . Int J Surg. .2016 ;(34):73-80

43. 2016 Low Incidence of Malignancy After Heart Transplantation in Taiwan . Transplant Proc. .2016 ;(48):974-977

44. 2015 Chiang MF,Chen HH,Chi CW,Sze CI,Hsu ML,Tsai JT. Modulation of Sonic hedgehog signaling and WW domain containing oxidoreductase WOX1 expression enhances radiosensitivity of human glioblastoma cells . Exp Biol Med .2015

45. 2015 Lin JC,Jen YM,Li MH,Chao HL,Tsai JT. Comparing outcomes of stereotactic body radiotherapy with intensity-modulated radiotherapy for patients with locally advanced unresectable pancreatic cancer . Eur J Gastroenterol Hepatol .2015 ;(27):259-264

46. 2015 KuoCY,LiouTH,Chan KH,Chi WC,Escorpizo R,Tsai JT. Functioning and Disability Analysis of Patients with Traumatic Brain Injury and Spinal Cord Injury by Using the World Health Organization Disability Assessment Schedule 2.0 . Int. J. Environ. Res. Public Health .2015 ;(12):4116-4127

47. 2015 Tsai JT,Lin CM,Chang CK,Cheng JT,Lin JW. Development of telmisartan in the therapy of spinal cord injury: pre-clinical study in rats . Drug Design, Development and Therapy .2015 ;(9):1-9

48. 2015 Lin JC,Tsai JT,Chang CC,Yen YM,Li MH,Liu WH. Comparing Treatment Plan in All Locations of Esophageal Cancer . Medicine .2015 ;(94):1-9

49. 2015 Liu SH,Chao KS,Leu YS,Lee JC,Liu CJ,Hyuang YC, Chang YF, Chen HW, Tsai JT, Chen YJ. Guideline and preliminary clinical practice results for dose specification and target delineation for postoperative radiotherapy for oral cavity cancer. . Head Neck .2015 ;(37):933-939

50. 2014 Chen MF,Tsai JT,Chen LJ,Wu TP,Yang JJ,Yin YL. Characterization of imidazoline receptors in blood vessels for development of antihypertensive agents . BioMed Research International .2014

51. 2014 Chen MF,Tsai JT,Chen JL,Wu TP,Yang JJ,Chiang TA. Antihypertensive action of allantoin in animals . Biomed Research International .2014

52. 2013 Tsai YC,Lin JW,Lai SC,Shiau AC,Hang CC,Tsai JT. Gamma Knife Perfexion Radiosurgery for Intraocular Tumor-Technique Establishment and Preliminary Results . Therapeut Radiol Oncol .2013 ;(20):179-190

53. 2013 Kuo CY,Shiau AC,Su YK,Chang CC,Yu HW,Tsai JT. 加馬刀與電腦刀應用於動靜脈畸形治療之臨床評估比較與劑量差異分析 . Therapeut Radiol Oncol .2013 ;(20):281-292

54. 2013 Tsai JT,Lin JW,Lin CM,Chen YH,Jen YM,Chen YH. Clinical Evaluation of CyberKnife in the Treatment of . BioMed Research International .2013 ;(2013):1-6

55. 2012 Lee HL, Chung TS,Ting LL,Tsai JT,Chen SW,Chiou JF,Leung WC. EGFR mutations are associated with favorable intracranial response and progression-free survival following brain irradiation in non-small cell lung cancer patients with brain metastases . Radiation Oncology .2012 ;(7):181

56. 2011 Kuo CY,Lin JW,Shiau AC,Yu SW,Chen SW,ChungTS. valuation of the Application of Synchrony Respiratory Tracking System of Cyberknife Radiotherapy . Therapeutic Radiology Oncology .2011 ;(8):1-15

57. 2011 Lee HL,Tsai JT,Chen SW,Lin JW,Lao WT,Wang KM. Early Experience of Stereotactic Body Radiotherapy in Patients with Primary and Metastatic Lung Tumors . Therapeutic Radiology and Oncology .2011 ;(18):111-124

58. 2010 Tsai JT,Liu HC,Chen YH. Suppression of InflammatoryMediators by Cruciferous Vegetable-Derived Indole-3-Carbinol and Phenylethyl Isothiocyanate in Lipopolysaccharide-ActivatedMacrophages . Mediators of Inflammation .2010

59. 2010 Hsieh CT,Tsai JT,Chang LP,Lin JW,Chang SD,Ju DT. Peritumoral edema after stereotactic radiosurgery for meningioma . Journal of Clinical Neuroscience .2010 ;(17):529-531

60. 2009 Tsai JT,Lin JW. Assessment of image-guided CyberKnife radiosurgery for metastatic spine tumors . J Neurooncol. .2009 ;(94):119-129

61. 2009 Lin JW,Shih CM,Chen YC,Lin CM,Tsai JT. Biochemical alteration in cerebrospinal fluid precedes behavioral deficits in Parkinsonian rats induced by 6-hydroxydopamine . Surgical Neurology .2009 ;(72):55-65

62. 2009 Tsai JT,Lin JW,Chu WC. An analysis of the Accuracy of the Robotic Respiratory Tracking Radiosurgical system in Extracranial Tumor . J. Chinese Oncol. Soc .2009 ;(25):184-194

63. 2008 Lin CM,Tsai JT,Lin MS,Lin JW,Su YK. Hypofractionated Cyberknife Stereotactic Radiosurgery for Acoustic Neuromas with and without Association to Neurofibromatosis Type 2J . J. Chinese Oncol. Soc. .2008 ;(24):30-40

64. 2008 Kuo CC,Yu HW,Huang KW,Chen CP,Chung TS. Evaluation of CyberKnife Treatment Planning for . Therapeut Radiol Oncol .2008 ;(15):301-310

65. 2008 Shun SC,Chiou JF,Yu PJ,Wei LL,Tsai JT,Kao CY, Jsiao YL. Changes in quality of life and its related factors in liver cancer patients receiving stereotactic radiation therapy . support care cancer .2008 ;(16):1059-1065

66. 2008 Changes in quality of life and its related factors in liver cancer patients receiving stereotactic radiation therapy. . Support Care Cancer. .2008 ;(16):1059-1065

67. 2008 Ju DT,Lin JW,Lin MS,Lee LM,Tseng HM. Hypofractionated CyberKnife stereotactic radiosurgery for acoustic neuromas with and without association to neurofibromatosis Type 2 . Acta Neurochir Suppl .2008 ;(101):169-173

68. 2008 Lin JW,Tsai JT,Lee LM,Lin CM,Hung CC. Effect of hyperbaric oxygen on patients with traumatic brain injury . Acta Neurochir Suppl .2008 ;(101):145-149

69. 2008 Lin CM,Lin JW,Tsai JT,Ko CP,Hung CC. Intracranial pressure fluctuation during hemodialysis in renal failure patients with intracranial hemorrhage . Acta Neurochir Suppl .2008 ;(101):141-144

70. 2008 Lin JW,Tsai JT,Lin CM,Lee LM,Hung KS. Evaluation of optimal cerebral perfusion pressure in severe traumatic brain injury. . Acta Neurochir Suppl .2008 ;(101):131-136

71. 2008 Lin JW,Tsai JT,LIn CM,Hung KS,Hung CC. Neurotrauma research in Taiwan . Acta Neurochir Suppl .2008 ;(101):113-117

72. 2007 Kuo CY,Lin JP,FU HM. Assurance procedure for Synchrony Respiratory Tracking system of CyberKnife System . Taiwanese Journal of Applied Radiation and Isotopes .2007 ;(3):385-396

73. 2007 Liao KH,Lin CM,Lin JW,Chen CY,Chiu WT. TheTreatment of Metastatic Brain Tumors with CyberKnife-A Preliminary Report . Journal Chinese Oncol. Soc. .2007 ;(23):1-8

74. 2007 Kung WM,Hung KS,Tsai JT,Chen CY,Lin JW. 電腦刀立體定位放射手術應用於脊椎腫瘤之治療 . 中華癌醫會誌 .2007 ;(23):19-30

75. 2007 YEUR-HUR LAI,SHIOW-CHING SHUN,YA-LI HSIAO SHUN,JENG-FONG CHIOUN,LIN-LINWEI,JO-TING TSAI, CHUNG-YU KAO. Fatigue Experiences in Hepatocellular Carcinoma Patients During Six Weeks of Stereotactic Radiotherapy . The oncologist .2007 ;(12):221-230

76. 2006 Tung-Ho Wu,Jeng-Fong Chiou,Ron Zhu,Kuang-Wei Huang,Pei-Fong Wong,Sam Tung,K.S. Clifford Chao. To Reduce Dose Inhomogeneit y at Neck Juncti on by Using a Rotati ng Collim ator on IMRT-Treated Head-and-neck Cancer Pati ents . [Therapeut Radiol Oncol .2006 ;(13):205-215

77. 2006 chiu-ting chen cp,chiu jf,huang yc,huang kw,lin jw,fu hm,chung ts,tsai jt. acceptance test for cyberknife unit . therapeut radiol oncol .2006 ;(133):197-204

78. 2006 Chen CP,Chiu JF,Huang YC,Huang KW,Lin JW. Acceptance Test For CyberKnife Unit . Therapeut Radiol Oncol .2006 ;(133):197-204

79. 2006 Chi-Yuan Yeh,Perng-An Lai,Kuang-Wei Huang,Chiu-Ping Chen,Jo-Ting Tsai. IMRT for a Malignant Mesothelioma . Therapeut Radiol Oncol .2006 ;(13):153-162

研究計畫

計畫名稱
113 pre-mRNA SRSF1與XIRP2在肝細胞癌抗輻射與轉移角色之交互作用機制探討(3/3)
補助單位
國家科學及技術委員會

計畫名稱
112 pre-mRNA SRSF1與XIRP2在肝細胞癌抗輻射與轉移角色之交互作用機制探討(2/3)
補助單位
國家科學及技術委員會

計畫名稱
111 pre-mRNA SRSF1與XIRP2在肝細胞癌抗輻射與轉移角色之交互作用機制探討(1/3)
補助單位
國家科學及技術委員會

計畫名稱
110 TAMs/CXCL6/CXCLR2腫瘤免疫交聯軸促進肝細胞癌之放射線治療抗性的機制研究
補助單位
科技部

計畫名稱
109 CXCL6/CXCL1 axis在PDK1訊號路徑介導的放射抗性肝細胞癌之分子機制探討
補助單位
科技部

計畫名稱
107 PG2 Concurrent with Chemoradiation for Locally Advanced Esophageal Cancer臨床檢體分析、臨床試驗資料處理暨統計分析研究計畫
補助單位
懷特生技新藥股份有限公司