張璽(Chang, Hsi ) 副教授

Email
jamesc@tmu.edu.tw
現   職
小兒學科 主任
小兒學科 副教授

學經歷

學 歷

畢業學校與學位[修業時間]
日本國立京都大學醫學部 博士
2003/04/01~2009/09/24
日本國立鹿兒島大學醫學系 學士
1995/04/01~2001/03/01

本校學術經歷

任職單位與職稱[起迄時間]
小兒學科副教授
2021/06/16~
小兒學科助理教授
2011/03/01~2017/03/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
小兒學科主任
2024/09/01 ~
(舊)臨床藥物基因體學暨蛋白質體學碩士學位學程助理教授
2015/08/01 ~ 2017/03/31

其它經歷

任職單位與職稱[起迄時間]
北醫附設醫院小兒部專任主治醫師

專長與研究領域

學門領域
pediatric neurology
stem cells
學術專長
幹細胞及再生醫學
幹細胞及再生醫學
多潛能幹細胞的研究
多潛能幹細胞的研究
肌肉及周邊神經疾病
肌肉及周邊神經疾病
小兒科
Pediatrics

論文著作

清冊下載


1. 2022 Transcranial photobiomodulation add-on therapy to valproic acid for pentylenetetrazole-induced seizures in peripubertal rats . BMC Complementary Medicine and Therapies .2022

2. 2022 Tsai CM,Chang SF,Li CC. Transcranial photobiomodulation (808 nm) attenuates pentylenetetrazole-induced seizures by suppressing hippocampal neuroinflammation, astrogliosis, and microgliosis in peripubertal rats . Neurophotonics .2022

3. 2022 Chung-Min Tsai,Yu-Chun Lo,Chuang-Yu Lin,Chun-Yin Hou,Ya-Li Huang,Hsi Chang. Toe-lift test: a novel, simple and noninvasive in vivo method for contractile evaluation of tibialis anterior muscle . Gen Physiol Biophys .2022

4. 2022 Min-Lan Tsai ,Chuang-Chin Wang ,Feng-Chin Lee,Syu-Jyun Peng ,Hsi Chang,Sung-Hui Tseng. Resting-State EEG Functional Connectivity in Children with Rolandic Spikes with or without Clinical Seizures . Biomedicines .2022

5. 2022 Tzu-Chien Chien ,Mu-Ming Chien, Tsai-Ling Liu, Hsi Chang,Min-Lan Tsai,Chia-Yau Chang , Kevin Li-Chun Hsieh, Tai-Tong Wong, Yen-Lin Liu. Adrenal Crisis Mimicking COVID-19 Encephalopathy in a Teenager with Craniopharyngioma . Child-Basel .2022

6. 2022 Min-Lan Tsai,Hsiu-Chen Lin, Chiung-Hui Yen, Jung-Tzu Ku , Shian-Ying Sung,Hsi Chang. Increased Risk of Tourette Syndrome with Leukotriene Modifier Use in Children with Allergic Diseases and Asthma: A Nationwide Population-Based Study . Child-Basel .2022

7. 2022 Chun-Yin Hou ,Ru Rutherford , Hsi Chang,Fong-Ching Chang,Liu Shumei,Chiung-Hui Chiu, Ping-Hung Chen, Jeng-Tung Chiang, Nae-Fang Miao, Hung-Yi Chuang, Chie-Chien Tseng. Children's mobile-gaming preferences, online risks, and mental health. . PLOS One .2022

8. 2021 Peng SJ,Wong TT,Huang CC,Chang H. Quantitative analysis of intraoperative electrocorticography mirrors histopathology and seizure outcome after epileptic surgery in children . J Formos Med Assoc .2021

9. 2021 Peng SJ,KLC Hsieh,Lin YK,Tsai ML,Wong TT,Chang H. Febrile seizures reduce hippocampal subfield volumes but not cortical thickness in children with focal onset seizures . Epilpsy Res .2021

10. 2020 Yu-Kai Kuo,Yu-Ching Lin,Ching-Yu Lee,Chih-Yu Chen,Jowy Tani,Tsung-Jen Huang, Hsi Chang, Meng-Huang Wu. Novel Insights into the Pathogenesis of Spinal Sarcopenia and Related Therapeutic Approaches: A Narrative Review . International Journal of Molecular Sciences .2020

11. 2020 Chung-Min Tsai,Shwu-Fen Chang,Hsi Chang. Transcranial photobiomodulation attenuates pentylenetetrazole-induced status epilepticus in peripubertal rats . Journal of Biophotonics .2020

12. 2020 Chuang‑Yu Lin,Chun‑Yin Hou,Chung‑Min Tsai,Hsi Chang. Muscle Type from which Satellite Cells are Derived Plays a Role in their Damage Response . Chinese Journal of Physiology .2020

13. 2020 Chuang-Yu Lin,Akira Niwa,Chun-Yin Hou,Chung-Min Tsai,Hsi Chang. Bidirectional myofiber transition through altering the photobiomodulation condition . Journal of Photochemistry & Photobillogy B: Biology .2020

14. 2020 Meng‑Huang Wu,Chuang‑Yu Lin,Chun‑Yin Hou,Ming‑Thau Sheu,Hsi Chang. Micronized sacchachitin promotes satellite cell proliferation through TAK1‑JNK‑AP‑1 signaling pathway predominantly by TLR2 activation . Chinese Medicine .2020

15. 2020 Peng SJ,Wong TT,Huang CC,Chang H,Hsieh LC,Tsai ML. Quantitative analysis of intraoperative electrocorticography mirrors histopathology and seizure outcome after epileptic surgery in children. . Journal of the Formosan Medical Association .2020

16. 2019 Yung-Ting Kou,Hui-Tien Liu,Chun-Yin Hou,Chuang-Yu Lin,Chung-Min Tsai,Hsi Chang. A transient protective effect of low-level laser irradiation against disuse-induced atrophy of rats . Lasers in Medical Science .2019

17. 2018 Yu-Jui Huang,Shih-Yun Lin,Kuo-Hsuan Chung,Hsi Chang. Oseltamivir-Associated Increased Libido in an Influenza B-Infected Adolescent. . Prim Care Companion CNS Disord .2018

18. 2018 Hsi Chang,Chung-Min Tsai,Chun-Yin Hou,Sung-Hui Tseng,Ju-Chin Lee,Min-Lan Tsai. Multiple subependymal pseudocysts in neonates play a role in later attention deficit hyperactivity and autistic spectrum disorder. . Journal of the Formosan Medical Association .2018

19. 2018 Min Lan Tsai,Chi Long Chen,Kevin Li Chun Hsieh,ames S. Miser,Hsi Chang,Yen Lin Liu, Tai-Tong Wong. Seizure characteristics are related to tumor pathology in children with brain tumors . Epilepsy Research .2018

20. 2012 Tomonari Awaya,Takeo Kato,Yuta Mizuno,Hsi Chang,Akira Niwa,Katsutsugu Umeda,Tatsutoshi Nakahata,Toshio Heike. Selective Development of Myogenic Mesenchymal Cells from Human Embryonic and Induced Pluripotent Stem cells . plos one .2012

21. 2011 Kawagoe S,Higuchi T,Li M,Shimizu H,Hirayama R,Fukuda T, Chang H, Nakahata T, Fukada S, Ida H, Kobayashi H, Ohashi T, Eto Y. Generation of induced pluripotent (iPS) cells derived from a murine model of Pompe disease and differentiation of Pompe-iPS cells derived from a murine model of Pompe disease and differentiation of Pompe-iPS cells into skeletal muscle cells. . MOLECULAR GENETICS AND METABOLISM .2011 ;(104):123-8

22. 2010 Mizuno Y,Chang H,Umeda K,Fukada S,Nakahata T,Heike T. Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells. . FASEB J. .2010 ;(july24):2245-53

23. 2009 Chang H,Umeda K,Iwasa T,Mizuno Y,Fukada S,Yamamoto H, Motohashi N, Miyagoe-Suzuki Y, Takeda S, Heike T, Nakahata T.. Generation of transplantable, functional satellite-like cells from mouse embryonic stem cells. . FASEB J. .2009 ;(23):1907-1919

24. 2009 Yoshimoto M,Heike T,Chang H,Kanatsu-Shinohara M,Baba S,Varnau JT, Shinohara T, Yoder MC, Nakahata T. Bone marrow engraftment but limited expansion of hematopoietic cells from multipotent germline stem cells derived from neonatal mouse testis. . Exp Hematol .2009 ;(37):1400-10

25. 2009 Niwa A,Umeda K,Chang H,Saito M,Okita K,,Takahashi K, Nakagawa M, Yamanaka S, Nakahata T, Heike T.. Orderly hematopoietic development of induced pluripotent stem cells via Flk-1(+) hemoangiogenic progenitors. . J Cell Physiol. .2009 ;(221):367-77

26. 2005 Yoshimoto M,Chang H,Shiota M,Kobayashi H,Umeda K,Kawakami A, Heike T, Nakahata T.. Two different roles of purified CD45+c-Kit+Sca-1+Lin- cells after transplantation in muscles.. 2005 May;23(5):610-618. (SCI; IF=7.741) . Stem Cells .2005 ;(5):610-618

27. 2004 Matsubara H,Watanabe K,Sakai H,Chang H,Fujino H,Higashi Y, Kobayashi M, Adachi S, Seto S, Nakahata T.. Rapid improvement of paraplegia caused by epidural involvements of Burkitt's lymphoma with chemotherapy. . Spine .2004 ;(1):4-6

28. 2004 Nishikomori R,Kanazawa N,Kanbe N,Okafuji I,Chang H,Kusunoki T, Heike T, Nakahata T.. Juvenile Sarcoidosis-modification of gene CARD15(NOD2). . Japanese Journal of Pedeatrics .2004 ;(56):1105-1110

29. 2004 Tanaka T,Matsubara H,Adachi S,Chang H,Fujino H,Higashi Y, Yasumi T, Kobayashi M, Watanabe K, Takahashi M, Kobayashi Y, Maruya E, Saji H, Nakahata T. Second transplantation from HLA 2-loci-mismatched mother for graft failure due to hemophagocytic syndrome after cord blood transplantation. . Int J Hematol. 2004 Dec;80(5):467-9. (SCI; IF =1.283 ) .2004 ;(30):467-9


1. 2022 Atypical Teratoid/Rhabdoid Tumor in Taiwan: A Nationwide, Population-Based Study . Cancers .2022

研究計畫

計畫名稱
113 光生物調節療法對專注力不足過動症鼠之治療效果評估
補助單位
國家科學及技術委員會

計畫名稱
112 貴機構依本會「補助國內研究生出席國際學術會議」申請費用補助案(研究生:細胞治療與再生醫學國際博士學位學程博士班Yhusi Karina Riskawati君),業經核定,請查照辦理。
補助單位
國家科學及技術委員會

計畫名稱
111 智慧型軟性MiniLED光療於肌肉減少症之動物實驗研究計畫
補助單位
群創光電股份有限公司

計畫名稱
104 在神經截斷或失用導致肌肉萎縮的動物模式下探討低能量雷射改善肌肉退化的效果
補助單位
臺北醫學大學

計畫名稱
103 探討因神經損傷引起肌肉萎縮過程中肌肉幹細胞所扮演之角色,以及利用脂肪幹細胞衍 生肌生性幹細胞行進移植治療之嘗試。(3/3)
補助單位
科技部

計畫名稱
102 探討因神經損傷引起肌肉萎縮過程中肌肉幹細胞所扮演之角色,以及利用脂肪幹細胞衍 生肌生性幹細胞行進移植治療之嘗試。(2/3)
補助單位
行政院國家科學委員會

計畫名稱
102 探討因神經損傷引起肌肉萎縮過程中肌肉幹細胞所扮演之角色,以及利用脂肪幹細胞衍 生肌生性幹細胞行進移植治療之嘗試(2-3)
補助單位
科技部

計畫名稱
102 探討因神經損傷引起肌肉萎縮過程中肌肉幹細胞所扮演之角色,以及利用脂肪幹細胞衍 生肌生性幹細胞行進移植治療之嘗試(3-3)
補助單位
科技部

計畫名稱
101 探討因神經損傷引起肌肉萎縮過程中肌肉幹細胞所扮演之角色,以及利用脂肪幹細胞衍 生肌生性幹細胞行進移植治療之嘗試。
補助單位
行政院國家科學委員會

計畫名稱
100 低能量雷射對老鼠胚胎幹細胞衍生之肌肉幹細胞之影響
補助單位
臺北醫學大學附設醫院