區慶建(Au, Heng-Kien) 助理教授

Email
hkau@tmu.edu.tw
現   職
婦產學科 助理教授

學經歷

學 歷

畢業學校與學位[修業時間]
臺北醫學大學醫學系 學士
1984/09~1991/06

本校學術經歷

任職單位與職稱[起迄時間]
婦產學科助理教授
2020/08/01~
婦產學科講師
2014/08/01~2020/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
(舊)細胞治療與再生醫學國際博士學位學程籌備處講師
2017/08/01 ~

其它經歷

任職單位與職稱[起迄時間]
台北醫學大學附設醫院婦產科產科主任
2002/08~
台北醫學大學附設醫院婦產部主治醫師
1998/08~
台北醫學大學附設醫院生殖醫學中心臨床研究醫師
1996/07~1998/06
台北醫學大學附設醫院婦產科住院醫師
1993/07~1996/06
嘉義聖馬爾定醫院婦產科住院醫師
1991/07~1993/06

專長與研究領域

學門領域
學術專長

論文著作

清冊下載


1. 2023 Yong-Sin Li , Hsin-Chien Lee,Jian-Pei Huang , Ya-Zhu Lin,Heng-Kien Au,Yu-Chun Lo, Ling-Chu Chien, Hsing-Jasmine Chao, Wanda Estinfort, Yi-Hua Chen. Adverse effects of inadequate sleep duration patterns during pregnancy on toddlers suspected developmental delay: A longitudinal study . Sleep Medicine .2023

2. 2023 Wu HY,Lin WY,Huang JP,Lin CL,Au HK,Lo YC, Chien LC, Chao HJ, Chen YH. Effects of mobile device use on emotional and behavioral problems in the CBCL among preschoolers: Do shared reading and maternal depression matter? . Plos One .2023

3. 2022 Kuo TC,Au HK,Chen SR, Roselyn Chipojola, Gabrielle T Lee,Lee PH, Kuo SY. Effects of an integrated childbirth education program to reduce fear of childbirth, anxiety, and depression, and improve dispositional mindfulness: A single-blind randomized controlled trial. . Midwifery .2022

4. 2022 Chen YC,Yeh YC,Lin YF,Au HK,Hsia SM,Chen YH, Hsieh RH. Aspartame Consumption, Mitochondrial Disorder-Induced Impaired Ovarian Function, and Infertility Risk. . Int J Mol Sci. .2022

5. 2022 Wanda Estinfort ,Huang JP,Au HK,Lin CL,Chen YY,Hsing Jasmine Chao, Chien LC, Lo YC, Chen YH. Effects of prenatal subjective well-being on birth outcomes and child development: A longitudinal study. . Eur Psychiatry. .2022

6. 2021 Au HK,Peng SW,Guo CL,Lin CC,Wang YL,Kuo YC, Law TY, Ho HN, Ling TY, Huang YH. Niche Laminin and IGF-1 Additively Coordinate the Maintenance of Oct-4 Through CD49f/IGF-1R-Hif-2α Feedforward Loop in Mouse Germline Stem Cells . Frontiers in Cell and Developmental Biology .2021

7. 2021 Wang CW,Chang TH,Chuang NC,Au HK,Chen CH,Tseng SH. Association between intracytoplasmic sperm injection and neurodevelopmental outcomes among offspring . PLoS One .2021

8. 2020 Raushan Alibekova, Jian-Pei Huang ,Tony Szu-Hsien Lee,Heng-Kien Au n, Yi-Hua Chen. Corrigendum to “Effects of smoking on perinatal depression and anxiety in mothers and fathers: A prospective cohort study” Journal of Affective Disorders 193(2016) 18-26] . J Affect Disord .2020

9. 2020 Wang HY,Huang JP,Lin CL,Au HK,Chen YH. Paternal influences from early pregnancy to postpartum years on child development: A longitudinal study. . J Affect Disord .2020

10. 2020 Tseng JF,Chen SR,Au HK,Chipojola P,Lee GT,Lee PH, Shyu MI, Kuo SY. Effectiveness of an integrated breastfeeding education to improve self-efficacy and exclusive breastfeeding rate: A single-blind, randomized controlled study. . Int J Nurs Stud. .2020

11. 2019 Chen YH,Huang JP,Au HK,Chen YH. High risk of depression, anxiety, and poor quality of life among experienced fathers, but not mothers: A prospective longitudinal study. . J Affect Disord .2019 ;(242):39-47

12. 2018 Kuo YC,Au HK,Hsu JL,Wang HF,Lee CJ,Peng SW, Lai SC, Wu YC, Ho HN, Huang YH. IGF-1R promotes symmetric self-renewal and migration of alkaline phosphatase+ germ stem cells through HIF-2α- OCT4/CXCR4 loop under hypoxia . Stem Cell Reports .2018 ;(10):524-537

13. 2018 Lin YH,Chen YH,Chang HY,Au HK,Tzeng CR,Huang YH. Chronic Niche Inflammation in Endometriosis-Associated Infertility: Current Understanding and Future Therapeutic Strategies. . Int J Mol Sci .2018 ;(19):E2385.

14. 2018 Lin YH,Chen YH,Chang HY,Au HK,Tzeng CR, Huang YH. Chronic niche inflammation in endometriosis-associated infertility: Current understanding and future therapeutic strategies . Int J Mol Sci .2018

15. 2016 Au HK,Liu CF,Tzeng CR,Chien Lw. Association between ultrasonographic parameters of Cesarean scar defect and outcome of early termination of pregnancy . Ultrasound Obstet Gynecol .2016 ;(47):506-510

16. 2016 Alibekova R,Huang JP,Lee TS,Au HK,Chen YH. Effects of smoking on perinatal depression and anxiety in mothers and fathers: A prospective cohort study . J Affect Disord .2016

17. 2015 Lu YY,Su ML,Gau ML,Lin KC,Au HK. The efficacy of cold-gel packing for relieving episiotomy pain - a quasi-randomised control trial. . Contemp Nurse .2015 ;(50):26-35

18. 2015 Au HK,Chang JH,Wu YC,Kuo YC,Chen YH,Lee WC, Chang TS, Lan PC, Kuo HC, Lee KL, Lee MT, Tzeng CR, Huang YH. TGF-βI Regulates Cell Migration through Pluripotent Transcription Factor OCT4 in Endometriosis. . PLoS One .2015 ;(10):e01452-e01452

19. 2013 Chang JH,Au HK,Lee WC,Chi CC,Lin TY,Wang LM, Kao SH, Huang YH, Tzeng CR. (2013) Expression of the pluripotent transcription factor OCT4 promotes cell migration in endometriosis . Fertil Steril .2013

20. 2013 Tzeng CR,Hwang JL,Au HK,Chien LW. Sonographic patterns of the endometrium in assessment of medical abortion outcomes . Contraception .2013

21. 2012 Huang CY,Lin FY,Shih CM,Au HK,Chang YJ,Nakagami H, Morishita R, Chang NC, Shyu KG, Chen JW. Moderate to high concentrations of high-density lipoprotein from healthy subjects paradoxically impair human endothelial progenitor cells and related angiogenesis by activating Rho-associated kinase pathways. . Arterioscler Thromb Vasc Biol .2012

22. 2012 Liao CJ,Huang YH,Au HK,Wang LM,Chu ST. The cancer marker neutrophil gelatinase-associated lipocalin is highly expressed in human endometrial . Mol Biol Rep .2012 ;(39):1029-1036

23. 2011 Chen CP,Lin YH,Au HK,Su YN,Hsu CY,Liu YP, Wu PC, Chern SR, Chen YT, Chen LF, Hsieh AH, Wang W. Chromosome 15q overgrowth syndrome: prenatal diagnosis, molecular cytogenetic characterization, and perinatal findings in a fetus with dup(15)(q26.2q26.3) . Taiwan J Obstet Gynecol .2011 ;(50):359-365

24. 2011 Chen CM,Li SC,Chen CY,Au HK,Shih CK,Hsu CY, Liu JF. Constituents in purple sweet potato leaves inhibit in vitro angiogenesis with opposite effects ex vivo. . Nutrition .2011

25. 2005 Chen HW,,Chen JJ,,Yu SL,,Li HN,,Yang PC,,Su CM, Au HK, Chang CW, Chien LW, Chen CS, Tzeng. Transcriptome analysis in blastocyst hatching by cDNA microarray. . Human Reproduction .2005 ;(20):2492-2501

26. 2005 Au HK,,Lin SH,,Huang SY,,Yeh TS,,Tzeng CR,,Hsieh RH.. Deleted mitochondrial DNA in human luteinized granulosa cells. . Ann N Y Acad Sci .2005 ;(1042):136-141

27. 2005 Au HK,,Yeh TS,,Kao SH,,Tzeng CR,,Hsieh RH.. Abnormal mitochondrial structure in human unfertilized oocytes and arrested embryos. . Ann N Y Acad Sci .2005 ;(1042):177-185

28. 2005 Tsai NM,,Hsieh RH,,Au HK,,Shieh MJ,,Huang SY,,Tzeng CR.. Effects of gonadotrophin-releasing hormone agonists on apoptosis of granulosa cells. . Ann N Y Acad Sci .2005 ;(1042):531-537

29. 2005 Au HK,,Yeh TS,,Kao SH,,Shih CM,,Hsieh RH,,Tzeng CR.. Calcium-dependent up-regulation of mitochondrial electron transfer chain gene expressions in human luteinized granulosa cells. . Fertility and sterility. .2005 ;(84):1104-1108

30. 2004 Chao JC,,Tseng HP,,Chang CW,,Chien YY,,Au HK,,Chen JR, Chen CF.. Chicken extract affects colostrum protein compositions in lactating women. . Journal of nutritional biochemistry. .2004 ;(15):37-44

31. 2004 Hsieh RH,,Au HK,,Yeh TS,,Chang SJ,,Cheng YF,,Tzeng CR.. Decreased expression of mitochondrial genes in human unfertilized oocytes and arrested embryos. . Fertility and sterility. .2004 ;(81):912-918

32. 2004 Chien LW,,Lee WS,,Au HK,,Tzeng CR.. Assessment of changes in utero-ovarian arterial impedance during the peri-implantation period by Doppler sonography in women undergoing assisted reproduction. . Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology .2004 ;(23):496-500

33. 2004 Yang WC,,Chen HW,,Au HK,,Chang CW,,Huang CT,,Yen YH, Tzeng CR.. Serum and endometrial markers. . Best practice & research. Clinical obstetrics & gynaecology. .2004 ;(18):305-318

34. 2002 Chien LW,,Au HK,,Xiao J,,Tzeng CR.. Fluid accumulation within the uterine cavity reduces pregnancy rates in women undergoing IVF. . Hum Reprod .2002 ;(17):351-356

35. 2002 Hsieh RH,,Tsai NM,,Au HK,,Chang SJ,,Wei YH,,Tzeng CR.. Multiple rearrangements of mitochondrial DNA in unfertilized human oocytes. . Fertility and sterility. .2002 ;(77):1012-1017

36. 2002 Chien LW,,Au HK,,Chen PL,,Xiao J,,Tzeng CR.. Assessment of uterine receptivity by the endometrial-subendometrial blood flow distribution pattern in women undergoing in vitro fertilization-embryo transfer. . Fertility and sterility. .2002 ;(78):245-251

37. 2001 Sheen TC,,Chen SR,,Au HK,,Chien YY,,Wu KY,,Tzeng CR.. Herniated blastomere following chemically assisted hatching may result in monozygotic twins. . Fertility and sterility. .2001 ;(75):442-444

研究計畫

計畫名稱
112 化療後卵巢早衰症之治療策略: 表現雌激素受體之胎盤間質幹細胞分泌體應用於卵巢微環境修復之分子機制與臨床研究
補助單位
國家科學及技術委員會

計畫名稱
110 非侵入性胎兒染色體基因診斷受測臨床驗證研究計畫
補助單位
台灣基康股份有限公司宜蘭分公司

計畫名稱
107 探討雌激素受體調控子宮內膜幹細胞特性之機制及其在子宮內膜異位症之臨床意義
補助單位
科技部

計畫名稱
106 探討胞外基質微環境與缺氧微環境共同透過IGF-1R–HIF-2a 中心訊號路徑促進胚胎期生殖系幹細胞之對稱性自我更新細胞增生及遷徙作用
補助單位
科技部

計畫名稱
104 探討缺氧環境中透過Hif-2α支配的CD49f—Igf-1r—Cxcr4訊號迴路調控小鼠生殖系幹細胞之多能性與遷移作用機制
補助單位
臺北醫學大學附設醫院

計畫名稱
91 以蛋白體學研究子宮內膜異位症相關之蛋白質
補助單位
臺北醫學大學

計畫名稱
90 哺乳類動物胚胎對粒腺體遺傳控制之研究
補助單位
臺北醫學大學

計畫名稱
89 研究經卵細胞質內精子注射術治療之新生兒及胚胎中父系粒線體之遺傳狀況
補助單位
臺北醫學大學