| 1. |
2021
Huang CR,Chang TW,Lee CT,Shen CJ,Chang WC,Chen BK.
ARNT deficiency represses pyruvate dehydrogenase kinase 1 to trigger ROS production and melanoma metastasis
. Oncogenesis
.2021
;(10):11-25
|
|
| 2. |
2021
Ho MH,Yen CH,Hsien TH,Kao TJ,Chiu JY,Chiang YH, Hoffer BJ, Chang WC, Chou SY .
CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury
. Redox Biology
.2021
;(46):102067-102080
|
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| 3. |
2021
Ajoy R,Lo YC,Ho MH,Chen YY,Wang Y,Chen YH, Chiu JY, Changou C, Hsiung YC, Chen HM, Chang TH, Lee CY, Chiang YH, Chang WC, Hoffer B, Chou SY.
CCL5 promotion of bioenergy metabolism is crucial for hippocampal synapse complex and memory formation
. Molecular Psychiatry
.2021
;(26):6451-6468
|
|
| 4. |
2021
Yang WB,Wu AC,Hsu TI,Liou JP,Lo LW,Chang KY, Chen PY, Kikkawa U, Yang ST, Kao TJ, Chen RM, Chang WC, Ko CY, Chuang JY.
Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells
. Cell Death & Disease.
.2021
;(12):884-896
|
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| 5. |
2020
Chiang KH,Shieh JM,Shen CJ,Chang TW,Wu PT,Hsu JY, Tsai JP, Chang WC, Chen BK.
Epidermal growth factor‐induced COX‐2 regulates metastasis of head and neck squamous cell carcinoma throug upregulation of angiopoietin‐like 4
. Cancer Sci
.2020
;(111):2004-2015
|
|
| 6. |
2020
Shen CJ,Chang KY,Ling BW,Ling WT,Su CM,Tsai JP, Liao YH, Hung LY, Chang WC, Chen BK.
Oleic acid-induced NOX4 is dependent on ANGPTL4 expression to promote human colorectal cancer metastasis
. Theranostics
.2020
;(10):7083-7099
|
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| 7. |
2020
Yang WB,Hsu CC,Hsu TI,Liou JP,Chang KY,Chen PY, Liu JJ, Yang ST, Wang JY, Yeh SH, Chen RM, Chang WC, Chuang, JY.
Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma
. Neuro-Oncol
.2020
;(22):1439-1451
|
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| 8. |
2020
Lee PT,Liévens JC,Wang SM,Chuang JY,Khalil B,Wu HE, Chang WC, Maurice T, Su TP.
Sigma-1 receptor chaperones rescue nucleocytoplasmic transport deficit seen in cellular and Drosophila ALS/FTD models
. Nat. Commun
.2020
;(11):5580-5593
|
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| 9. |
2019
Wang CH,Hung PW,Chaing CW,Lombes M,Chen CH,Lee KH, Lo YC, Wu MH, Chang WC, Lin DY.
Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation
. BBA-Molecular Cell Research
.2019
;(1866):1282-1297
|
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| 10. |
2019
Tsai YT,Wu AC,Yang WB,Kao TJ,Chaung JY,Chang WC, Hsu TI.
ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade
. Int. J Mol. Sci
.2019
;(20):5625-5640
|
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| 11. |
2019
Chen TC,Chuang JY,Ko CY,Kao TJ,Yang PY,Yu CH, Liu MS, Hu SL, Tsai YT, Chan H, Chang WC, Hsu TI.
AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-mediated redox homeostasis
. Redox Biol
.2019
;(30):101413-101425
|
|
| 12. |
2018
Wu CC,Lee PT,Kao TJ,Chou SY,Su RY,Lee YC, Yeh SH, Liou JP, Hsu TI, Su TP, Chuang CK, Chang WC, Chuang JY.
Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress.
. Redox Biology
.2018
;(19):74-80
|
|
| 13. |
2018
Yang WB,Chuang JY,Ko CY,Chang WC,Hsu TI.
Dehydroepiandrosterone induces temozolomide resistance through modulating phosphorylation and acetylation of Sp1 in glioblastoma.
. Mol. Neurobiol
.2018
;(56):2301-2313
|
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| 14. |
2017
Lai, C.H.,Huang, Y.C.,Lee, J.C.,Joseph Tseng, T.C.,Chang, K.C.,Chen, Y.J., Ding, N.J., Huang, P.H., Chang, W.C., Lin, B.W., Chen, R.Y., Wang, Y.C., Lai, Y.C. and Hung, L.Y..
Translational upregulation of Aurora-A by hnRNP Q1 contributes to cell proliferation and tumorigenesis in colorectal cancer
. Cell Death and Disease
.2017
;(8):e2555
|
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| 15. |
2017
Lee, K.H.,Chen, C.L.,Lee, Y.C.,Kao, T.J.,Chen, K.Y.,Fang, C.Y., Chang, W.C., Chiang, Y.H. and Huang, C.C..
Znf179 induces differentiation and growth arrest of human primary glioblastoma multiforme in a p53-dependent cell cycle pathway
. Sci. Rep.
.2017
;(7):4787
|
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| 16. |
2017
Wong, H.S.,Chang, C.M.,Kao, C.C.,Hsu, Y.W.,Liu, X.,Chang, W.C., Wu, M.S. and Chang, W.C..
V-J combinations of T-cell receptor predict responses to erythropoietin in end-stage renal disease patients
. J. Biomed. Sci.
.2017
;(24):43
|
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| 17. |
2017
Ko CY,Lin CH,Chuang JY,Chang WC,Hsu TI.
MDM2 degrades deacetylated nucleolin through ubiquitination to promote glioma stem-like cell enrichment for chemotherapeutic resistance
. Mol Neurobiol.
.2017
;(55):3211-3223
|
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| 18. |
2017
Chuang JY,Lo WL,Ko CY,Chou SY,Chen RM,Chang KY, Hung JJ, Su WC, Chang WC, Hsu TI.
Upregulation of CYP17A1 by Sp1-mediated DNA demethylation confers temozolomide resistance through DHEA-mediated protection in glioma.
. Oncogenesis
.2017
;(6):e339-e350
|
|
| 19. |
2017
Hsu JY,Chang JY,Chang KY,Chang WC,Chen BK.
Epidermal growth factor-induced pyruvate dehydrogenase kinase 1 expression enhances head and neck squamous cell carcinoma metastasis via up-regulation of fibronectin
. FASEB J
.2017
;(10):4265-4276
|
|
| 20. |
2017
Chuang JY,Kao TJ,Lin SH,Wu AC,Lee PT,Su TP, Yeh SH, Lee YC, Wu CC, Chang WC.
Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury
. Redox Biol.
.2017
;(11):135-143
|
|
| 21. |
2017
Hung, C.Y.,Wang, Y.C.,Chuang, J.Y.,Yiung, M.J.,Liaw, H.,Chang, W.C. and Hung, J.J..
Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression
. Sci. Rep.
.2017
;(7):9166
|
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| 22. |
2017
Chang, K.Y.,Huang, C.T.,Hsu, T.I.,Hsu, C.C.,Liu, J.J.,Chuang, C.K., Hung, J.J., Chang, W.C., Tsaia K.K. and Chuang, J.Y..
Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma
. Biochem. Biophys. Res. Commun.
.2017
;(493):14-19
|
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| 23. |
2016
Hsu, T.I.,Wang, Y.C.,Hung, C.Y.,Yu, C.H.,Su, W.C.,Chang, W.C. and Hung, J.J..
Positive feedback regulation between IL10 and EGFR promotes lung cancer formation.
. Oncotarget
.2016
;(7):20840-20854
|
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| 24. |
2016
Yang CP,Kuo YL,Lee YC,Lee KH,Chiang CW,Wang JM, Hsu CC, Chang WC and Lin DY.
RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription.
. Biochemical and Biophysical Research Communications
.2016
;(478):873-880
|
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| 25. |
2016
Su, T.C.,Lin, S.H.,Lee, P.T.,Yeh, S.H.,Hiseh, T.H.,Chou, S.Y., Su, T.P., Hung, J.J., Chang, W.C., Lee, Y.C. and Chuang, J.Y..
The sigma-1 receptor-Zinc finger protein 179 pathway protects against hydrogen peroxide-induced cell injury.
. Neuropharmacology
.2016
;(105):1-9
|
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| 26. |
2016
Tsou, J.H.,Yang, Y.C.,Pao, P.C.,Lin, H.C.,Huang, N.K.,Lin, S.T., Hsu, K.S., Yeh, C.M., Lee, K.H., Kuo, C.J., Yang, D.M., Lin, J.H., Chang, W.C., Lee, Y.C..
Important roles of ring finger protein 112 in embryonic vascular development and brain functions.
. Molecular Neurobiology
.2016
|
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| 27. |
2016
Hsu, C.C.,Chang, W.C.,Hsu, T.I.,Liu, J.J.,Yeh, S.H.,Wang, J.Y., Liou. J.P., Ko, C.Y., Chang, K.Y. and Chuang, J.Y..
Suberoylanilide hydroxamic acid represses glioma stem-like cells.
. J. Biomed. Sci.
.2016
;(23):81
|
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| 28. |
2016
Wang, S.A.,Wang, Y.C.,Chuang, Y.P.,Huang, Y.H.,Su, W.C.,Chang, W.C. and Hung, J.J..
EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression plays a crucial role in tumorigenesis.
. Oncogene
.2016
|
|
| 29. |
2016
Chuang JY,Kao TJ,Lin SH,Wu AC,Lee PT,Su TP, Yeh SH, Lee YC, Wu CC, Chang WC.
Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury.
. Redox Biology
.2016
;(11):135-143
|
|
| 30. |
2016
Wang, W.J.,Li, C.F.,Chu, Y.Y.,Wang, Y.H.,Hour, T.C.,Yen, C.J., Chang, W.C. and Wang. J.M..
Inhibition of EGFR/STAT3/CEBPD axis reverses cisplatin cross-resistance with paclitaxel in urothelial carcinoma of urinary bladder
. Clin Cancer Res.
.2016
;(23):503-513
|
|
| 31. |
2015
Ko CY,Chang WC,Wang JM.
Biological roles of CCAAT/Enhancer-binding protein delta during inflammation.
. J. Biomed. Sci.
.2015
;(22):6
|
|
| 32. |
2015
Huang CR,Lee CT,Chang KY,Chang WC,Liu YW,Lee JC, Chen BK.
Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin β1/FAK axis.
. Oncotarget
.2015
;(6):11530-11546
|
|
| 33. |
2015
Hsu TI,Chen YJ,Hung CY,Wang YC,Lin SJ,Su WC, Lai MD, Kim SY, Wang Q, Qian K, Goto M, Zhao Y, Kashiwada Y, Lee KH, Chang WC, Hung JJ.
A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy.
. Oncotarget
.2015
;(6):13671-13687
|
|
| 34. |
2015
Lee YC,Huang CC,Lin DY,Chang WC,Lee KH.
Overexpression of centromere protein K (CENPK) in ovarian cancer is correlated with poor patient survival and associated with predictive and prognostic relevance.
. PeerJ
.2015
;(3):e1386
|
|
| 35. |
2015
Tsai SY,Chuang JY,Tsai MS,Wang XF,Xi ZX,Hung JJ, Chang WC, Bonci A, Su TP.
Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope.
. PNAS
.2015
;(112):E6562-6570
|
|
| 36. |
2015
Wang, Y.C.,Wang, S.A.,Chen, P.H.,Hsu, T.I.,Yang, W.B.,Chuang, Y.P., Su, W.C., Liaw, H.J., Chang, W.C. and Hung, J.J..
Variants of ubiquitin-specific peptidase 24 play a crucial role in lung cancer malignancy.
. Oncogene
.2015
;(35):3669-3680
|
|
| 37. |
2015
Yang CP,Chiang CW,Chen CH,Lee YC,Wu MH,Tsou YH, Yang YS, Chang WC, Lin DY.
Erratum: Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58).
. J Biomed. Sci.
.2015
;(22):33
|
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| 38. |
2015
Huang, C.L.,Chao, C.C.,Lee, Y.C.,Lu, M.K.,Cheng, J.J.,Yang, Y.C., Wang, V.C., Chang, W.C. and Huang N.K..
Paraquat induces cell death through impairing mitochondrial membrane permeability.
. Mol. Neurobiol.
.2015
;(53):2169-2188
|
|
| 39. |
2014
Tsai YT,Chang CM,Wang JY,Hou MF,Wang JM,Shiurba R, Chang WC and Chang WC.
Functional of DNA methyltransferase 3a in lead (Pb21)-induced cyclooxygenase-2 gene.
. Environ Toxicology
.2014
;(30):1024-1032
|
|
| 40. |
2014
Ko CY,Chu YY,Narumiya S,Chi JY,Furuyashiki T,Aoki T,Wang SM, Chang WC and Wang JM.
The CCAAT/enhancer-binding protein delta/miR135a/thrombospondin 1 axis mediates PGE2-induced angiogenesis in Alzheimer’s disease.
. Neurobiology of Aging
.2014
;(36):1356-1368
|
|
| 41. |
2014
Yang WB,Chen PH,Hsu TI,Fu TF,Su WC,Liaw H, Chang WC, Hung JJ.
Sp1-mediated microRNA-182 expression regulates lung cancer progression.
. Oncotarget
.2014
;(5):740-753
|
|
| 42. |
2014
Wang SA,Hung CY,Chuang JY,Chang WC,Hsu TI,Hung JJ.
Phosphorylation of p300 increases its protein degradation to enhance the lung cancer progression.
. Biochimica Biophysica Acta-MCR
.2014
;(1843):1135-1149
|
|
| 43. |
2014
Shieh JM,Shen CJ,Chang WC,Cheng HC,Chan YY,Huang WC, Chang WC, Chen BK.
An increase in reactive oxygen species by deregulation of ARNT enhances chemotherapeutic drug-induced cancer cell death.
. Plos One
.2014
;(9):e99242
|
|
| 44. |
2014
Hung CY,Yang WY,Wang SA,Hsu TI,Chang WC,Hung JJ.
Nucleolin enhances internal ribosomal entry site (IRES)-mediated translation of Sp1 in tumorigenesis article type.
. BBA-Molecular Cell Research
.2014
;(1843):2843-2854
|
|
| 45. |
2014
Yang HC,Chuang JY,Jeng WY,Liu CI,Wang AH,Lu PJ, Chang WC and Hung JJ.
Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis.
. Nucleic Acids Research
.2014
;(42):13573-13587
|
|
| 46. |
2014
Hsu TI,Lin SC,Lu PS,Chang WC,Hung CY,Yeh YM, Su WC, Liao PC and Hung JJ.
MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy.
. Oncogene
.2014
;(34):826-837
|
|
| 47. |
2014
Hsu JY,Chang KY,Chen SH,Lee CT,Chang ST,Cheng HC, Chang WC and Chen BK.
Epidermal growth factor-induced cyclooxygenase-2 enhances head and neck squamous cell carcinoma metastasis through fibronectin up-regulation.
. Oncotarget
.2014
;(6):1723-1739
|
|
| 48. |
2013
Ko SC,Huang CR,Shieh JM,Yang JH,Chang WC,Chen BK.
Epidermal Growth Factor Protects Squamous Cell Carcinoma against Cisplatin-Induced Cytotoxicity through Increased Interleukin-1beta Expression
. PLOS ONE
.2013
;(8):e55795
|
|
| 49. |
2013
Lin LF,Li CF,Wang WJ,Yang WM,Wang DH,Chang WC, Lee WH, Wang JM.
Loss of ZBRK1 Contributes to the Increase of KAP1 and Promotes KAP1-Mediated Metastasis and Invasion in Cervical Cancer
. PLOS ONE
.2013
;(8):e73033
|
|
| 50. |
2013
Yang ST,Yen CJ,Lai CH,Lin YJ,Chang KC,Lee JC, Liu YW, Chang-Liao PY, Hsu LS, Chang WC, Hung WC, Tang TK, Liu YW, Hung LY.
SUMOylated CPAP is required for IKK-mediated NF-kappaB activation and enhances HBx-induced NF-kappaB signaling in HCC
. Journal of Hepatology
.2013
;(58):1157-1164
|
|
| 51. |
2013
Chan YY,Kalpana S,Chang WC,Chang WC,Chen BK.
Expression of aryl hydrocarbon receptor nuclear translocator enhances cisplatin resistance by upregulating MDR1 expression in cancer cells
. Mol Pharmacol
.2013
;(84):591-602
|
|
| 52. |
2013
Tsai, CW,Lai, FJ,Sheu, HM,Lin, YS,Chang, TH,Jan, MS, Chen, SM, Hsu, PC, Huang, TT, Huang, TC, Sheen, MC, Chen, ST, Chang, WC, Chang, NS, Hsu, LJ.
WWOX suppresses autophagy for inducing apoptosis in methotrexate-treated human squamous cell carcinoma
. Cell Death and Disease
.2013
;(4):e792
|
|
| 53. |
2013
Ko CY,Wang WL,Wang SM,Chu YY,Chang WC,Wang JM.
GSK3beta-mediated CCAAT/enhancer-binding protein delta phosphorylation in astrocytes promotes migration and activation of microglia/macrophages.
. Neurobiology of Aging
.2013
;(35):24-34
|
|
| 54. |
2013
Hsu CC,Chen CH,Hsu TI,Hung JJ,Ko JL,Zhang B, Lee YC, Chen HK, Chang WC, Lin DY.
The 58-kDa microspherule protein (MSP58) represses human telomerase reverse transcriptase (hTERT) gene expression and cell proliferation by interacting with telomerase transcriptional element-interacting factor (TEIF)
. BBA-Molecular Cell Research
.2013
;(1843):565-579
|
|
| 55. |
2013
Lin DY,Huang CC,Hsieh YT,Lin HC,Pao PC,Tsou JH, La CY, Hung LY, Wang JM, Chang WC, Lee YC.
Analysis of the interaction between Zinc finger protein 179 (Znf179) and promyelocytic leukemia zinc finger (Plzf).
. J. Biomed. Sci.
.2013
;(20):98
|
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| 56. |
2013
Chen YP,Lin HJ,Cen JS,Tsai MY,Hsieh HP,Chang JY, Chen NF, Chang KC, Huang WT, Su WC, Yang ST, Chang WC, Hung LY, Chen TY.
CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to aurora kinase-A inhibitors.
. Int. J. Cancer
.2013
;(135):751-762
|
|
| 57. |
2012
Hsu TI,Wang MC,Chen SY,Huang St,Yeh YM,Su WC, Chang WC, Hung JJ.
Betulinic Acid Decreases Specificity Protein 1 (Sp1) Level via Increasing the Sumoylation of Sp1 to Inhibit Lung Cancer Growth
. Mol Pharmacol
.2012
;(82):1115-1128
|
|
| 58. |
2012
Chang WC,Hung JJ.
Functional role of post-translational modifications of Sp1 in tumorigenesis
. Journal of Biomedical Science
.2012
;(19):94
|
|
| 59. |
2012
Chang LH,Huang HS,Wu PT,Jou IM,Pan MH,Chang WC, Wang DH, Wang JM.
Role of Macrophage CCAAT/Enhancer Binding Protein Delta in the Pathogenesis of Rheumatoid Arthritis in Collagen-Induced Arthritic Mice
. PLoS One
.2012
;(7):e45378
|
|
| 60. |
2012
Chan SH,Kikkawa U,Matsuzaki H,Chen JH,Chang WC.
Insulin receptor substrate-1 prevents autophagydependent cell death caused by oxidative stress in mouse NIH/3T3 cells
. Journal of Biomedical Science
.2012
;(19):64-79
|
|
| 61. |
2012
Hsu CC,Lee YC,Yeh SH,Chen CH,Wu CC,Wang TY, Chen YN, Hung LY, Liu YW, Chen HK, Hsiao YT, Wang WS, Tsou JH, Tsou YH, Wu MH, Chang WC, Li.
58-kDa Microspherule Protein (MSP58) Is Novel Brahma-related Gene 1 (BRG1)-associated Protein That Modulates p53/p21 Senescence Pathway
. The Journal of Biological Chemistry
.2012
;(287):25333-25348
|
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| 62. |
2012
Chuang JY,Wang SA,Yang WB,Hung CY,Su TP,Chang WC, Hung JJ.
Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells
. Oncogene
.2012
;(31):4946-4959
|
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