陳亦仁(Chen, Yi-Jen)　教授

Email
yjchen@tmu.edu.tw
現   職
臨床醫學研究所 教授

學經歷

學　歷

畢業學校與學位[修業時間]
國立陽明大學臨床醫學研究所 博士
1998/09~2002/07
私立臺北醫學院醫學系 學士
1985/09/01~1992/06/01

本校學術經歷

任職單位與職稱[起迄時間]
臨床醫學研究所教授
2008/02/01~
臨床醫學研究所副教授
2007/08/01~2008/01/31
內科學科副教授
2005/02/01~2007/07/31
內科學科助理教授
2001/08/01~2005/01/31
內科學科講師
1998/08/01~2001/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
國際醫學研究碩士學位學程教授
2018/02/01 ~
國際醫學研究博士學位學程教授
2018/02/01 ~
國際醫學研究博士學位學程教授
2016/11/01 ~ 2017/10/31
國際醫學研究碩士學位學程教授
2016/11/01 ~ 2017/10/31
臨床醫學研究所教授
2009/09/01 ~
內科學科教授
2009/09/01 ~
臨床醫學研究所所長
2007/08/01 ~ 2010/07/31

其它經歷

任職單位與職稱[起迄時間]
國立陽明大學兼任講師
1998/08/01~
萬芳醫院主治醫師
1998/07/01~
國防醫學院兼任講師
1997/08/01~1998/07/31
國立陽明大學兼任臨床講師
1997/08/01~1998/07/31
榮民總醫院總醫師
1995/07/01~1998/06/30
榮民總醫院住院醫師
1992/10/12~1995/06/30

專長與研究領域

學門領域
Basic and Clinical Electrophysiology
Mechanisms of Arrhythmia
學術專長
Patch Clamp
Immunofluorescene
PCR
Western Blot
Gene Cloning
Primary Cardiac fibroblast isolation
Heart failare animal

論文著作

清冊下載

論文 Journal Paper


1. 2024 Cheng Tzu Yu,Chen Yao Chang,Li Shao Jung,Lin Fong Jhih,Lu Yen Yu,Lee Ting I,Lee Ting Wei, Higa Satoshi, Kao Yu Hsun, Chen Yi Jen. Interleukin-33/ST2 axis involvement in atrial remodeling and arrhythmogenesis . Translational Research .2024 ;(268):1-12

2. 2024 Chin Chye Gen,Chen Yao Chang,Lin Fong Jhih,Lin Yung Kuo,Lu Yen Yu,Cheng Tzu Yu, Chen Shih Ann, Chen Yi Jen. Targeting NLRP3 signaling reduces myocarditis-induced arrhythmogenesis and cardiac remodeling . Journal of Biomedical Science .2024 ;(31)

3. 2023 Chung Cheng Chih,Lin Yung Kuo,Chen Yao Chang,Kao Yu Hsun,Yeh Yung Hsin,Trang Nguyen Ngoc,Chen Yi Jen,. Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis . Cardiovascular Diabetology .2023 ;(22)

4. 2023 Liu Chih Min,Lin Fong Jhih,Chen Yao Chang,Lin Yung Kuo,Lu Yen Yu,Chan Chao Shun,Higa Satoshi,Chen Shih Ann,Chen Yi Jen,Liu Chih Min,Lin Fong Jhih,Chen Yao Chang,Lin Yung Kuo,Lu Yen Yu,Chan Chao Shun,Higa Satoshi,Chen Shih Ann,Chen Yi Jen. Modulation of post-pacing action potential duration and contractile responses on ventricular arrhythmogenesis in chloroquine-induced long QT syndrome . European Journal of Pharmacology .2023 ;(941)

5. 2022 Chin Chye Gen,Elimam Ahmed Moustafa,Lin Fong Jhih,Chen Yao Chang,Lin Yung Kuo,Lu Yen Yu,Higa Satoshi,Chen Shih Ann,Hsieh Ming Hsiung,Chen Yi Jen,. Effects of Adrenomedullin on Atrial Electrophysiology and Pulmonary Vein Arrhythmogenesis . International Journal of Molecular Sciences .2022 ;(23)

6. 2022 Lee Ting Wei,Chung Cheng Chih,Lee Ting I.,Lin Yung Kuo,Kao Yu Hsun,Chen Yi Jen,Lee Ting Wei,Chung Cheng Chih,Lee Ting I.,Lin Yung Kuo,Kao Yu Hsun,Chen Yi Jen. Fibroblast growth factor 23 stimulates cardiac fibroblast activity through phospholipase c‐mediated calcium signaling . International Journal of Molecular Sciences .2022 ;(23)

7. 2022 Li Shao Jung,Cheng Wan Li,Kao Yu Hsun,Chung Cheng Chih,Trang Nguyen Ngoc,Chen Yi Jen,. Melatonin Inhibits NF-κB/CREB/Runx2 Signaling and Alleviates Aortic Valve Calcification . Frontiers in Cardiovascular Medicine .2022 ;(9)

8. 2022 Galectin-3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling . Acta Physiologica .2022 ;(234)

9. 2021 ZFHX3 knockdown dysregulates mitochondrial adaptations to tachypacing in atrial myocytes through enhanced oxidative stress and calcium overload . Acta Physiologica .2021 ;(231)

10. 2021 Huang Shih Yu,Chen Yao Chang,Kao Yu Hsun,Lu Yen Yu,Lin Yung Kuo,Higa Satoshi,Chen Shih Ann,Chen Yi Jen. Calcium dysregulation increases right ventricular outflow tract arrhythmogenesis in rabbit model of chronic kidney disease . Journal of Cellular and Molecular Medicine .2021 ;(25):11264-11277

11. 2021 Lee Ting Wei,Lee Ting I.,Lin Yung Kuo,Chen Yao Chang,Kao Yu Hsun,Chen Yi Jen. Effect of antidiabetic drugs on the risk of atrial fibrillation: mechanistic insights from clinical evidence and translational studies . CELLULAR AND MOLECULAR LIFE SCIENCE .2021

12. 2021 Yugo Dony,Chen Yao Chang,Lin Yung Kuo,Liu Chih Min,Huang Jen Hung,Chen Shih Ann,Chen Yi Jen. Effects of phosphodiesterase-1 inhibitor on pulmonary vein electrophysiology and arrhythmogenesis . EUR J CLINICAL INVESTIGATION .2021 ;(51)

13. 2020 Cheng WL,Kao YH,Chen YC,Lin YK,Chen SA ,Chen YJ. Macrophage migration inhibitory factor increases atrial arrhythmogenesis through CD74 signaling . Transl Res .2020 ;(216):43-56

14. 2020 Yuan Hung,Yao-Chang Chen ,Shih‐Yu Huang ,Yen-Yu Lu,Yung-Kuo Lin, Yu-Hsun Kao, Wei-Shiang Lin, Shih-Ann Chen, Yi-Jen Chen. Klotho Modulates Electrical Activity and Calcium Homeostasis in Pulmonary Vein Cardiomyocytes via PI3K/Akt Signaling . Europace .2020 ;(in press)

15. 2020 Chan CS, Lin YS,Lin YK,Chen YC,Kao YH, Hsu CC, Chen SA, Chen YJ. Atrial arrhythmogenesis in a rabbit model of chronic obstructive pulmonary disease . Translational Research .2020

16. 2020 Jun-Hei Chang,Chen-Chuan Cheng,Yen-Yu Lu,Yao-Chang Chen,Yao-Chang Chen,Yi-Jen Chen. Trastuzumab increases pulmonary vein arrhythmogenesis through modulating pulmonary vein electrical and conduction properties via phosphatidylinositol 3-kinase signaling . Iranian Journal of Basic Medical Sciences .2020

17. 2020 Liu Chih Min,Lin Feng Zhi,Chen Yao Chang,Lin Yung Kuo,Lu Yen Yu,Wu Cheng I.,Higa Satoshi,Chen Shih Ann,Chen Yi Jen,Liu Chih Min,Lin Feng Zhi,Chen Yao Chang,Lin Yung Kuo,Lu Yen Yu,Wu Cheng I.,Higa Satoshi,Chen Shih Ann,Chen Yi Jen. Concurrent increases in post-pacing action potential duration and contractility predict occurrence of ventricular arrhythmia . Pflugers Archiv European Journal of Physiology .2020

18. 2020 Lee Ting Wei,Lee Ting I.,Lin Yung Kuo,Chen Yao Chang,Kao Yu Hsun,Chen Yi . Effect of antidiabetic drugs on the risk of atrial fibrillation: mechanistic insights from clinical evidence and translational studies . Cellular and Molecular Life Sciences .2020

19. 2020 Baigalmaa Lkhagva, Yung-Kuo Lin,Yao-Chang Chen,Wan-Li Cheng,Satoshi Higa,Yu-Hsun Kao, | Yi-Jen Chen. ZFHX3 knockdown dysregulates mitochondrial adaptations to tachypacing in atrial myocytes through enhanced oxidative stress and calcium overload . Acta Physiologica   .2020

20. 2019 Huang JH,Chen YC,Lu YY,Lin YK,Chen SA,Chen YJ. Arginine vasopressin modulates electrical activity and calcium homeostasis in pulmonary vein cardiomyocytes. . J Biomed Sci .2019 ;(26):71-71

21. 2019 Lee Ting I.,Chen Yao Chang,Lin Yung Kuo,Chung Cheng Chih,Lu Yen Yu,Kao Yu Hsun,Chen Yi Jen. Empagliflozin Attenuates Myocardial Sodium and Calcium Dysregulation and Reverses Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats . International Journal of Molecular Sciences .2019 ;(20)

22. 2019 Li Shao Jung,Kao Yu Hsun,Chung Cheng Chih,Cheng Wan Li,Chen Yi Jen. Hdac i inhibitor regulates runx2 transactivation through canonical and non-canonical wnt signaling in aortic valvular interstitial cells . American Journal of Translational Research .2019 ;(11):744-754

23. 2019 Chan Chao Shun,Lin Yung Kuo,Chen Yao Chang,Lu Yen Yu,Chen Shih Ann,Chen Yi Jen. Heart failure differentially modulates natural (Sinoatrial node) and ectopic (pulmonary veins) pacemakers: Mechanism and therapeutic implication for atrial fibrillation . International Journal of Molecular Sciences .2019 ;(20)

24. 2019 Lithium interacts with cardiac remodeling: the fundamental value in the pharmacotherapy of bipolar disorder . Progress in Neuro-Psychopharmacology and Biological Psychiatry .2019 ;(88):208-214

25. 2019 Cheng WL, Kao YH, Chao TF,Lin YK,Chen SA,Chen YJ. MicroRNA-133 suppresses ZFHX3-dependent atrial remodelling and arrhythmia . Acta Physiologica .2019 ;(27):e13322

26. 2019 Lee Ting I.,Kao Yu Hsun,Baigalmaa Lkhagva,Lee Ting Wei,Lu Yen Yu,Chen Yao Chang,Chao Tze Fan,Chen Yi Jen. Sodium hydrosulphide restores tumour necrosis factor-α-induced mitochondrial dysfunction and metabolic dysregulation in HL-1 cells . Journal of Cellular and Molecular Medicine .2019

27. 2019 Therapeutic potential of vitamin D in AGE/RAGE-related cardiovascular diseases . Cellular and Molecular Life Sciences .2019

28. 2018 Lee T W, Lee T I, Lin YK,Kao YH,Chen YJ. Calcitriol downregulates fibroblast growth factor receptor 1 through histone deacetylase activation in HL-1 atrial myocytes . Journal of Biomedical Science .2018 ;(25):42-.

29. 2018 Lin Yung Kuo ,Chen Yi Ann ,Lee Ting I. ,Chen Yao Chang ,Chen Shih Ann ,Chen Yi Jen. Aging modulates the substrate and triggers remodeling in atrial fibrillation . Circulation Journal .2018 ;(82):1237-1244

30. 2018 Chan Chao Shun ,Lin Yung Kuo ,Kao Yu Hsun ,Chen Yao Chang ,Chen Shih Ann ,chen Yi Jen. Hydrogen sulphide increases pulmonary veins and atrial arrhythmogenesis with activation of protein kinase C . Journal of Cellular and Molecular Medicine .2018

31. 2018 Lkhagva Baigalmaa ,Kao Yu Hsun ,Lee Ting I. ,Lee Ting Wei ,Cheng Wan Li ,Chen Yi Jen. Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities . Epigenetics .2018

32. 2018 Chung Cheng Chih ,Lin Yung Kuo ,Chen Yao Chang ,Kao Yu Hsun ,Yeh Yung Hsin ,Chen Yi Jen. Factor Xa inhibition by rivaroxaban regulates fibrogenesis in human atrial fibroblasts with modulation of nitric oxide synthesis and calcium homeostasis . Journal of Molecular and Cellular Cardiology .2018 ;(123):128-138

33. 2018 Chang Chien Jung ,Li Shao Jung ,Chen Yao Chang ,Huang Shih Yu ,Chen Shih Ann ,Chen Yi Jen. Histone deacetylase inhibition attenuates atrial arrhythmogenesis in sterile pericarditis . Translational Research .2018

34. 2018 Lin Yung Kuo ,Chen Yi Ann ,Lee Ting I. ,Chen Yao Chang ,Chen Shih Ann ,Chen Yi Jen. Aging modulates the substrate and triggers remodeling in atrial fibrillation . Circulation Journal .2018 ;(82):1237-1244

35. 2018 Chang Chien Jung ,Cheng Chen Chuan ,Chen Yao Chang ,Higa Satoshi ,Huang Jen Hung ,Chen Shih-Ann, Chen Yi-Jen . Factor Xa inhibitors differently modulate electrical activities in pulmonary veins and the sinoatrial node . European Journal of Pharmacology .2018 ;(833):462-471

36. 2018 Calcitriol downregulates fibroblast growth factor receptor 1 through histone deacetylase activation in HL-1 atrial myocytes . Journal of Biomedical Science .2018 ;(25)

37. 2018 Lu Yen Yu ,Wu Wen Shiann ,Lin Yung Kuo ,Cheng Chen Chuan ,Chen Yao Chang ,Chen Shih-Ann, Chen Yi-Jen. Angiotensin 1-7 modulates electrophysiological characteristics and calcium homoeostasis in pulmonary veins cardiomyocytes via MAS/PI3K/eNOS signalling pathway . European Journal of Clinical Investigation .2018 ;(48):e12854-e12854

38. 2018 Chen Yen Chou ,Chung Cheng Chih ,Lin Yung Kuo ,Chen Yi Jen . Genetic and ethnic modulation of cardiovascular toxicity of vascular endothelial growth factor inhibitors . Annals of Medicine .2018 ;(50):46-56

39. 2017 Activated p300 acetyltransferase activity modulates aortic valvular calcification with osteogenic transdifferentiation and downregulation of Klotho . International Journal of Cardiology .2017 ;(232):271-279

40. 2017 Lee Ting Wei ,Kao Yu Hsun ,Lee Ting I. ,Chen Yi Jen . ADAM10 modulates calcitriol-regulated RAGE in cardiomyocytes . European Journal of Clinical Investigation .2017 ;(47):675-683

41. 2017 Lu Yen Yu ,Cheng Chen Chuan ,Tsai Chin Feng ,Lin Yung Kuo ,Lee Ting I. ,Chen YC, Chen SA, Chen YJ. Discrepant effects of heart failure on electrophysiological property in right ventricular outflow tract and left ventricular outflow tract cardiomyocytes . Clinical Science .2017 ;(131):1317-1327

42. 2017 Huang Shih Yu ,Chen Yao Chang ,Kao Yu Hsun ,Hsieh Ming Hsiung ,Lin Yung Kuo ,Chen SA, Chen YJ. Redox and activation of protein kinase A dysregulates calcium homeostasis in pulmonary vein cardiomyocytes of chronic kidney disease . Journal of the American Heart Association .2017 ;(6)

43. 2017 Chang Shih Lin ,Chuang Hui Lun ,Chen Yao Chang ,Kao Yu Hsun ,Lin Yung Kuo ,Yeh YH, Chen SA, Chen YJ. Heart failure modulates electropharmacological characteristics of sinoatrial nodes . Experimental and Therapeutic Medicine .2017 ;(13):771-779

44. 2017 Li Shao Jung ,Kao Yu Hsun ,Chung Cheng Chih ,Chen Wei Yu ,Cheng Wan Li ,Cheng Wan-li, Chen Yi-Jen. Activated p300 acetyltransferase activity modulates aortic valvular calcification with osteogenic transdifferentiation and downregulation of Klotho . International Journal of Cardiology .2017 ;(232):271-279

45. 2017 Chung Cheng Chih ,Kao Yu Hsun ,Yao CJ,Lin Yung,Chen Yi-Jen. A comparison of left and right atrial fibroblasts reveals different collagen production activity and stress-induced mitogen-activated protein kinase signalling in rats. . Acta Physiol (Oxf). .2017 ;(220):432-445

46. 2016 Cheng WL,Kao YH,Chen SA,Chen YJ. Pathophysiology of cancer therapy-provoked atrial fibrillation. . Int J cardiol .2016

47. 2016 Huang JH,Lin YK,Hsieh MH,Chiu WC,Chen YJ. 127.Huang JH, Lin YK, Hsieh MH, Chiu WC, Chen YJ*. Age and Thyroid Hormone Replacement Delays the Recovery from Amiodarone-Induced Hypothyroidism . Int J cardiol .2016

48. 2016 Huang SY,Chen YC,Kao YH,Hsieh MH,Chen YA,Chen WP, Lin YK, Chen SA, Chen YJ. Renal failure induces atrial arrhythmogenesis from discrepant electrophysiological remodeling and calcium regulation in pulmonary veins, sinoatrial node, and atria. Int . Int J Cardiol .2016 ;(202):846-857

49. 2016 Chien-Jung Chang,Chen-Chuan Cheng,Yao-Chang Chen,Yu-Hsun Kao,Shih-Ann Chen,Yi-Jen Chen. Gap junction modifiers regulate electrical activities of the sinoatrial node and pulmonary vein: Therapeutic implications in atrial arrhythmogenesis . Int J Cardiol .2016 ;(221):529-536

50. 2016 Lkhagva B,Kao YH,Chen YC,Chao TF,Chen SA,Chen YJ. Targeting histone deacetylases: A novel therapeutic strategy for atrial fibrillation . Eur J Pharmacol .2016

51. 2016 Lkhagva B,Kao YH,Chen YC,Chao TF,Chen SA,Chen YJ. Targeting histone deacetylases: A novel therapeutic strategy for atrial fibrillation . Eur J Pharmacol .2016

52. 2016 Kao YH,Hsu JC,Chen YC,Lin YK,Lkhagva B,Chen SA, Chen YJ. ZFHX3 knockdown increases arrhythmogenesis and dysregulates calcium homeostasis in HL-1 atrial myocytes . Int J Cardiol .2016

53. 2016 Huang JH,Chen YC,Lee TI,Kao YH,Chazo TF,Chen SA, Chen YJ. Glucagon-like peptide-1 regulates calcium homeostasis and electrophysiological activities of HL-1 cardiomyocytes . Peptides .2016 ;(78):91-98

54. 2016 Lu YY,Chen YC,Kao YH,Lin YK,Yeh YH,Chen SA, Chen YJ. Colchicine modulates calcium homeostasis and electrical property of HL-1 cells . J Cell Mol Med .2016 ;(20):1182-1190

55. 2016 Lu YY,Cheng CC,Chen YC,Lin YK,Chen SA,Chen YJ. Electrolyte disturbances differentially regulate sinoatrial node and pulmonary vein electrical activity: A contribution to hypokalemia- or hyponatremia-induced atrial fibrillation . Heart Rhythm .2016 ;(13):781-788

56. 2016 Lu YY,Lin YK,Kao YH,Chung CC,Yeh YH,Chen SA, Chen YJ. Collagen regulates transforming growth factor-β receptors of HL-1 cardiomyocytes through activation of stretch and integrin signaling. . Mol Med Rep. .2016 ;(14):3429-3436

57. 2016 Huang SY,Chen YC,Kao YH,Hsieh MH,Lin YK,Chung CC, Lee TI, Tsai WC, Chen SA, Chen YJ. Fibroblast growth factor 23 dysregulates late sodium current and calcium homeostasis with enhanced arrhythmogenesis in pulmonary vein cardiomyocytes. . oncotarget .2016

58. 2015 Jung-Chieh Hsu,Chen-Chuan Cheng,Yu-Hsun Kao,Yao-Chang Chen,Cheng-Chih Chung,Yi-Jen Chen. Testosterone regulates cardiac calcium homeostasis with enhanced ryanodine receptor 2 expression through activation of TGF-β . International Journal of Cardiology .2015 ;(190):11-14

59. 2015 Chien-Jung Chang,Chen-Chuan Cheng,Ten-Fang Yang,Yao-Chang Chen,Lin YK,Chen SA, Chen YJ. Selective and non-selective non-steroidal anti-inflammatory drugs differentially regulate pulmonary vein and atrial arrhythmogenesis . Int J Cardiol .2015 ;(184):559-567

60. 2015 Tsai WC,Lu YY,Chen YC,Chang CJ,Kao YH,Lin YK, Chen YH, Chen SA, Yang LY, Chen YJ.. Ablation of androgen receptor gene triggers right ventricular outflow tract ventricular tachycardia. . Int J Cardiol. .2015 ;(189):172-181

61. 2015 Chan CS, Lin YJ, Cha,Lin YJ,Chang SL,Lo LW,Hu YF,Chao TF, Chung FP, Liao JN, Chen YJ, Chen SA.. Early repolarization of surface ECG predicts fatal ventricular arrhythmias in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy and symptomatic ventricular arrhythmias. . Int J Cardiol .2015

62. 2015 Chong E,Chang SL,Hsiao YW,Singhal R,Liu SH,Leha T, Lin WY, Hsu CP, Chen YC, Chen YJ, Wu TJ, Hig. Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation. . Heart Rhythm .2015 ;(12):1046-1056

63. 2015 Hu YF,Chen YJ,Lin YJ,Chen SA. Inflammation and the pathogenesis of atrial fibrillation. . Nat Rev Cardiol .2015 ;(12):230-243

64. 2015 Lee TW,Lee TI,Chang CJ,Lien GS,Kao YH,Chao TF, Chen YJ.. Potential of vitamin D in treating diabetic cardiomyopathy. . Nutr Res .2015 ;(35):269-279

65. 2015 Chung CC,Kao YH,Lu YY,Chen YJ.. Reply to the letter "androgens in cardiac fibrosis and other cardiovascular mechanisms". . Int J Cardiol .2015

66. 2015 Lkhagva B,Lin YK,Kao YH,Chazo TF,Chung CC,Chen SA, Chen YJ. Novel Histone Deacetylase Inhibitor Modulates Cardiac Peroxisome Proliferator-Activated Receptors and Inflammatory Cytokines in Heart Failure. . pharmacology .2015 ;(96):184-91

67. 2014 Kao YH,Chen YC,Lin YK,Shiu RJ,Chao TF,Chen SA, Chen YJ.. FGF-23 dysregulates calcium homeostasis and electrophysiological properties in HL-1 atrial cells. . Eur J Clin Invest .2014 ;(44):795-801

68. 2014 Huang CS,Chen CI,Liu YT,Huang JH,Chen YJ. CHA2DS2-VASc Score and Heart Rate Predict Ischemic Stroke Outcomes in Patients with Atrial Fibrillation . Acta Cardiologica Sinica .2014 ;(30):16-21

69. 2014 Kao YH,Lien GS,Chao TF,Chen YJ. DNA methylation inhibition: a novel therapeutic strategy for heart failure. . Int J Cardiol .2014 ;(176):232-233

70. 2014 Kao YH,Lien GS,Chao TF,Chen YJ. DNA methylation inhibition: a novel therapeutic strategy for heart failure. . Int J Cardiol .2014 ;(176):232-233

71. 2014 Lu YY,Chen YJ.. A randomized trial of colchicine for acute pericarditis. . N Engl J Med. .2014 ;(370):780-781

72. 2014 Huang,Lin YK,Hsieh MH,Chen SA,Chen YJ. Non-standard dose dronedarone in treating atrial fibrillation patients. . Int J Cardiol. .2014 ;(172):e214-e216

73. 2014 Lu YY,Chung FP,Chen YC,Tsai CF,Kao YH,Chao TF, Huang JH, Chen SA, Chen YJ.. Distinctive electrophysiological characteristics of right ventricular out-flow tract cardiomyocytes. . J Cell Mol Med. .2014 ;(18):1540-1548

74. 2014 Lee TW,Kao YH,Lee TI,Chang CJ,,,,, Lien GS,Chen YJ.. Calcitriol modulates receptor for advanced glycation end products (RAGE) in diabetic hearts. . Int J Cardiol. .2014 ;(173):236-241

75. 2014 Hanafy DA,Chang SL,Lu YY,Chen YC,Kao YH,Huang JH, Chen SA, Chen YJ. Electromechanical effects of 1,25-dihydroxyvitamin d with antiatrial fibrillation activities. . J Cardiovasc Electrophysiol .2014 ;(25):317-323

76. 2014 Singhal R,Chang SL,Chong E,Hsiao YW,Liu SH,Tsai YN, Hsu CP, Lin YJ, Lo LW, Ha TL, Chen YC, Chen. Colchicine suppresses atrial fibrillation in failing heart. . Int J Cardiol. .2014 ;(176):651-660

77. 2014 Lin YK,Chen YC,Huang JH,Lin YJ,,Huang SS,,Chen SA, Chen YJ.. Leptin modulates electrophysiological characteristics and isoproterenol-induced arrhythmogenesis in atrial myocytes. . J Biomed Sci. .2014

78. 2014 Chen YC,Lu YY,Cheng CC,Lin YK,Chen SA,Chen YJ.. Sinoatrial node electrical activity modulates pulmonary vein arrhythmogenesis. . Int J Cardiol .2014 ;(173):447-452

79. 2014 Chien-Jung Chang,Ten-Fang Yang,Tin-I Lee,Yao-Chang Chen,Yu-Hsun Kao,Shih-Ann Chen,Yi-Jen Chen. Sitagliptin Modulates the Electrical and Mechanical Characteristics of Pulmonary Vein and Atrium . Acta Cardiol;ogica sinica .2014 ;(30):29-37

80. 2014 Shih-Yu Huang,Yen-Yu Lu,Yao-Chang Chen,Wei-Ta Chen,Yung-Kuo Lin,Shih-Ann Chen and Yi-Jen Chen. Hydrogen Peroxide Modulates Electrophysiological Characteristics of Left Atrial Myocytes . Acta Carcdiologica Sinica .2014 ;(30):38-45

81. 2014 Hung-Yu Yang,Jen-Hung Huang,Yung-Kuo Lin,Chien-Yeh Hsu,Shih-Ann Chen,Yi-Jen Chen. Bipolar Disorder and Schizophrenia Present Different Risks of Atrial fibrillation: A Nationwide Population-Based Analysis . Acta Cardiologica sinica .2014 ;(30):46-52

82. 2014 Cheng-Chih Chung,,Yu-Hsun Kao,Jing-Ping Liou,Yi-Jen Chen. Curcumin Suppress Cardiac Fibroblasts Activities by Regulating Proliferation, Migration, and the Extracellular Matrix . Acta Cardiologica Sinixa .2014 ;(30):474-482

83. 2014 Chung CC,Hsu RC,Kao YH,Liou JP,Lu YY,Chen YJ. Androgen attenuates cardiac fibroblasts activations through modulations of transforming growth factor-β and angiotensin II signaling. . Int J Cardiol. .2014 ;(176):386-393

84. 2014 Chung CC,Hsu RC,Kao YH,Liou JP,Lu YY,Chen YJ. Androgen attenuates cardiac fibroblasts activations through modulations of transforming growth factor-β and angiotensin II signaling. . Int J Cardiol. .2014 ;(176):386-393

85. 2014 Lin YK,Chen YC,Kao YH,Tsai CF,Yeh YH,Huang JL, Cheng CC, Chen SA, Chen YJ.. A monounsaturated fatty acid (oleic acid) modulates electrical activity in atrial myocytes with calcium and sodium dysregulation. . Int J Cardiol .2014 ;(176):191-198

86. 2014 Lee TI,Kao YH,Chen YC,Tsai WC,Chung CC,Chen YJ. Cardiac metabolism, inflammation, and peroxisome proliferator-activated receptors modulated by 1,25-dihydroxyvitamin D3 in diabetic rats. . Int J Cardiol. 2014 .2014 ;(176):151-157

87. 2014 Tsai WC,Lee TI,Chen YC,Kao YH,Lu YY,Lin YK, Chen SA, Chen YJ.. Testosterone replacement increases aged pulmonary vein and left atrium arrhythmogenesis with enhanced adrenergic activity. . Int J Cardiol. 7 .2014 ;(176):110-118

88. 2014 Chen WT,Chen YC,Hsieh MH,Huang SY,,Kao YH,Chen YA, Lin YK, Chen SA, Chen YJ.. The Uremic Toxin Indoxyl Sulfate Increases Pulmonary Vein and Atrial Arrhythmogenesis. . J Cardiovasc Electrophysiol. 2014 .2014

89. 2013 Lee TI,Chen YC,Kao YH,Hsiao FC,Lin YK,Chen YJ. Rosiglitazone induces arrhythmogenesis in diabetic hypertensive rats with calcium handling alteration. . Int J Cardiol. .2013 ;(165):299-307

90. 2013 Lee TI,Chen YC,Kao YH,Hsiao FC,Lin YK,Chen YJ. Rosiglitazone induces arrhythmogenesis in diabetic hypertensive rats with calcium handling alteration. . Int J Cardiol. 2013 .2013 ;(165):299-307

91. 2013 Lee TI,Chen YC,Kao YH,Hsiao FC,Lin YK,Chen YJ. Rosiglitazone induces arrhythmogenesis in diabetic hypertensive rats with calcium handling alteration. . Int J Cardiol. 2013 .2013 ;(165):299-307

92. 2013 Lee TI,Chen YC,Kao YH,Hsiao FC,Lin YK,Chen YJ. Rosiglitazone induces arrhythmogenesis in diabetic hypertensive rats with calcium handling alteration. . Int J Cardiol. 2013 .2013 ;(165):299-307

93. 2013 Huang JH,Chiu WC,Hsu MI,Chen YJ. Effects of androgen on vascular and inflammatory biomarkers in a female hypertensive population . Gynecol Endocrinol. .2013 ;(29):340-344

94. 2013 Wang CA,Chen WT,Lin YC,Hsieh MH,Chen YJ. Different coronary artery calcium scores with discrepant progression risks . Int J Cardiol .2013

95. 2013 Chen YC,Huang JH,Lin YK,Hsieh MH,Chen YJ. 99.Chen YC, Huang JH, Lin YK, Hsieh MH, Chen YJ*. Gender modulates the aging effects on different patterns of early repolarization. . Heart Vessels .2013

96. 2013 Lin YK,Chen YJ. Adipocytokinesmodulateioniccurrents – A keytolipotoxicitypotentiated cardiacarrhythmia. J Arrhythmia 2013 . . J Arrhythmia 2013 .2013

97. 2013 Kao YH,Chiu WC,Hsu MI,Chen YJ. Endothelial Progenitor Cell Dysfunction in Polycystic Ovary Syndrome: Implications for the Genesis of Cardiovascular Diseases. . Int J Fertil Steril .2013 ;(6):208-213

98. 2013 Chung CC,Kao YH,Chen YJ,Chen YJ. Androgen modulates cardiac fibrosis contributing to gender differences on heart failure. . Aging Male. .2013 ;(16):22-27

99. 2013 Lee TI,Kao YH,Chen YC,Huang JH,Hsiao FC,Chen YJ. Peroxisome proliferator-activated receptors modulate cardiac dysfunction in diabetic cardiomyopathy. . Diabetes Res Clin Pract. .2013 ;(100):330-9

100. 2013 Lee TI,Kao YH,Chen YC,Huang JH,Hsu MI,Chen YJ. The dipeptidyl peptidase-4 inhibitor-sitagliptin modulates calcium dysregulation, inflammation, and PPARs in hypertensive cardiomyocytes. . Int J Cardiol. 2013 .2013

101. 2013 Hanafy DA,Chen YC,,Chang SL,Lu YY,Lin YK,Kao YH, Chen SA, Chen YJ. Different effects of dronedarone and amiodarone on pulmonary vein electrophysiology, mechanical properties and H2O2-induced arrhythmogenicity. . Eur J Pharmacol. 2013 .2013 ;(28):1-3

102. 2013 Chang SL,Chen YC,Hsu CP,Kao YH,Lin YK,Lin YJ, Wu TJ, Chen SA, Chen YJ. Electrophysiological characteristics of complex fractionated electrograms and high frequency activity in atrial fibrillation. . Int J Cardiol. 2013 .2013

103. 2013 Chang CJ,Chen YC,Lin YK,Huang JH,Chen SA,Chen YJ. Rivaroxaban modulates electrical and mechanical characteristics of left atrium. . J Biomed Sci. 2013 .2013

104. 2013 Lu YY,Chen YC,Kao YH,Chen SA,Chen YJ. Extracellular matrix of collagen modulates arrhythmogenic activity of pulmonary veins through p38 MAPK activation. . J Mol Cell Cardiol. 2013 Jun;59:159-66 .2013 ;(59):159-166

105. 2013 Kao YH,Chen YC,Chung CC,Lien GS,Chen SA,Kuo CC, Chen YJ. Heart failure and angiotensin II modulate atrial Pitx2c promotor methylation.Clin Exp Pharmacol Physiol. . Clin Exp Pharmacol Physiol .2013 ;(40):379-384

106. 2013 Chang CJ,Chen YC,Kao YH,Lin YK,Chen SA,Chen YJ. Response to letter regarding article, "Dabigatran and thrombin modulate electrophysiological characteristics of pulmonary vein and left atrium" by Chang et al. . Circ Arrhythm Electrophysiol. 2013 A .2013

107. 2013 Tsai WC,Yang LY,Chen YC,Kao YH,Lin YK,Chen SA, Cheng CF, Chen Y. Ablation of the androgen receptor gene modulates atrial electrophysiology and arrhythmogenesis with calcium protein dysregulation. . Endocrinology. .2013 ;(154):2833-2842

108. 2013 Hanafy DA,Chang SL,Lu YY,Chen YC,Kao YH,Huang JH, Chen SA, Chen YJ. Electromechanical Effects of 1,25-Dihydroxyvitamin D with Anti-Atrial Fibrillation Activities. . J Cardiovasc Electrophysiol. .2013

109. 2013 Chen WT,Chen YC,Lu YY,Kao YH,Huang JH,Lin YK, Chen SA, Chen YJ. Apamin modulates electrophysiological characteristics of the pulmonary vein and the Sinoatrial Node. . Eur J Clin Invest. .2013 ;(43):957-963

110. 2013 Chang SL,Chen YC,Hsu CP,Kao YH,Lin YK,Lai YJ, Yeh HI, Higa S, Chen SA, Chen YJ. Heat shock protein inducer modifies arrhythmogenic substrate and inhibits atrial fibrillation in the failing heart. . Int J Cardiol. .2013

111. 2013 Kao YH,Liou JP,Chung CC,Lien GS,Kuo CC,Chen SA, Chen YJ. Histone deacetylase inhibition improved cardiac functions with direct antifibrotic activity in heart failure. . Int J Cardiol. .2013

112. 2013 Tsai WC,Chen YC,Kao YH,Lu YY,Chen SA,Chen YJ. Distinctive sodium and calcium regulation associated with sex differences in atrial electrophysiology of rabbits. . Int J Cardiol. .2013

113. 2013 Lin YK,Chen YC,Chang SL,Lin YJ,Chen JH,Yeh YH, Chen SA, Chen YJ. Heart failure epicardial fat increases atrial arrhythmogenesis. . Int J Cardiol .2013 ;(167):1979-1983

114. 2012 Chen WT,Huang JH,Hsieh MH,Chen YJ. Extremely high coronary artery calcium score is associated with a high cancer incidence. . Int J Cardiol. .2012 ;(155):474-475

115. 2012 Lin YK,Chen YC,Chang SL,Lin YJ,Chen JH,Yeh YH, Chen SA, Chen YJ.*. Heart Failure Epicardial Fat Increases Atrial Arrhythmogenesis. . Int J Cardiol. .2012

116. 2012 Cheng CC,Weerateerangkul P,Lu YY,Chen YC,Lin YK,Chen SA, Chen YJ. Apelin regulates the electrophysiological characteristics of atrial myocytes. . Eur J Clin Invest .2012

117. 2012 Lin YK,Chen YC,Chen JH,Chen SA,Chen YJ. Adipocytes modulate the electrophysiology of atrial myocytes: implications in obesity-induced atrial fibrillation. . Basic Res Cardiol. .2012 ;(107):293

118. 2012 Lu YY,Cheng CC,Chen YC,Chen SA,Chen YJ. ATX-II-induced pulmonary vein arrhythmogenesis related to atrial fibrillation and long QT syndrome. . Eur J Clin Invest. .2012 ;(42):823-831

119. 2012 Tsao HM,Weerateerangkul P,Chen YC,Kao YH,Lin YK,Huang JH, Chen SA, Chen YJ.. Amyloid peptide regulates calcium homoeostasis and arrhythmogenesis in pulmonary vein cardiomyocytes. . Eur J Clin Invest. .2012 ;(42):589-98

120. 2012 Yang HY,Chiu WC,Huang JH,Hsu CY,Lin YK,Chen YJ. Analysis of 10-year nationwide population-based data on sex differences in hospitalization for heart failure. . Heart Vessels .2012

121. 2012 Yang HY,Huang JH,Hsu CY,Chen YJ. Gender differences and the trend in the acute myocardial infarction: a 10-year nationwide population-based analysis. . ScientificWorldJournal .2012 ;(10)

122. 2012 Chang CJ,Chen YC,Kao YH,Lin YK,Chen SA,Chen YJ*. Dabigatran and thrombin modulate electrophysiological characteristics of pulmonary vein and left atrium . Circ Arrhythm Electrophysiol .2012 ;(5):1176-1183

123. 2011 Chang SL,Chen YC,Yeh YH,Lai YJ,Yeh HI,Lin CI, Lin YJ, Wu TJ, Huang YK, Chen SA, Chen YJ. Heart Failure Enhances Arrhythmogenesis in Pulmonary Veins . Clin Exp Pharmacol Physiol .2011

124. 2011 Tsai WC,Chen YC,Lin YK,Chen SA,Chen YJ. Sex Differences in the Electrophysiological Characteristics of Pulmonary Veins and Left Atrium and Their Clinical Implication in Atrial Fibrillation . Circ Arrhythm Electrophysiol .2011 ;(4):550-559

125. 2011 Lu YY,Chen YC,Kao YH,Wu TJ,Chen SA,Chen YJ. Extracellular matrix of collagen modulates intracellular calcium handling and electrophysiological characteristics of HL-1 cardiomyocytes with activation of angiotensin II type 1 receptor . J Card Fail .2011 ;(17):82-90

126. 2011 Kao YH,Cheng CC,Chen YC,Chung CC,Lee TI,Chen SA, Chen YJ. Hydralazine-induced promoter demethylation enhances sarcoplasmic reticulum Ca2+-ATPase and calcium homeostasis in cardiac myocytes . Lab Invest .2011

127. 2011 Lee TI,Kao YH,Chen YC,Pan NH,Lin YK,Chen YJ. Cardiac peroxisome-proliferator-activated receptor expression in hypertension co-existing with diabetes . Clin Sci (Lond) .2011 ;(121):305-312

128. 2011 Kazuyoshi Suenari,Chen YC,Kao YH,Chen CC,Lin YK,Yasuki Kihara,ChenYJ,Chen SA. Eicosapentaenoic acid reduces the pulmonary vein arrhythmias through nitric oxide . Life Sciences .2011 ;(89):129-136

129. 2011 Tsai CF,Chen YC,Lin YK,Chen SA,Chen YJ. Electromechanical effects of the direct renin inhibitor (aliskiren) on the pulmonary vein and atrium. . Basic Res Cardiol. .2011

130. 2011 Cheng CC,Huang CF,Chen YC,Lin YK,Kao YH,Chen YJ, Chen SA.. Heat-stress responses modulate beta-adrenergic agonist and angiotensin II effects on the arrhythmogenesis of pulmonary vein cardiomyocytes. . J Cardiovasc Electrophysiol. .2011 ;(22):183-190

131. 2011 Suenari K,Chen YC,Kao YH,Cheng CC,Lin YK,Chen YJ, Chen SA.. Discrepant electrophysiological characteristics and calcium homeostasis of left atrial anterior and posterior myocytes. . Basic Res Cardiol. .2011 ;(106):65-74

132. 2011 Huang JH,Lin YK,Hsieh MH,Chen SA,Chen YJ. Thyroxine monotherapy without amiodarone enhances atrial fibrillation recurrences in amiodarone-induced hypothyroidism. . Int J Cardiol. .2011

133. 2011 Suenari K,Cheng CC,Chen YC,Lin YK,Nakano Y,Kihara Y, Chen SA, Chen YJ.. Effects of Ivabradine on the Pulmonary Vein Electrical Activity and Modulation of Pacemaker Currents and Calcium Homeostasis. . J Cardiovasc Electrophysiol. .2011

134. 2011 Lee TI,Chen YC,Kao YH,Hsiao FC,Lin YK,Chen YJ. Rosiglitazone induces arrhythmogenesis in diabetic hypertensive rats with calcium handling alteration. . Int J Cardiol. .2011

135. 2011 Huang JH,Yang HY,Hsu CY,Lin YK,Chen SA,Chen YJ. Gender differences in trend of hospital management for atrial fibrillation: A nationwide population-based analysis. . Int J Cardiol. .2011

136. 2011 Lin YK,Lai MS,Chen YC,Cheng CC,Huang JH,Chen SA, Chen YJ, Lin CI.. Hypoxia and reoxygenation modulate the arrhythmogenic activity of the pulmonary vein and atrium. . Clin Sci .2011 ;(122):121-132

137. 2011 Tsao HM,Punate Weerateerangk,Chen YC,Kao YH,Lin YK,Huang JH,Chen SA ,Chen YJ.. Amyloid peptide regulates calcium homeostasis and arrhythmogenesis in pulmonary vein cardiomyocytes. . European Journal of clinical Investigation (Eur J Clin Invest) .2011

138. 2011 Lin YK,Chen YC,Chen SA,Chen YJ. Ion Channel Remodeling in Pulmonary Vein Arrhythmogenesis for Atrial Fibrillation. . J Exp Clin Med. .2011 ;(3):108-111

139. 2011 Chang SL,Chen YC,Yeh YH,Lin YK,Wu TJ,Lin CI, Chen SA, Chen YJ.. Heart Failure Enhanced Pulmonary Vein Arrhythmogenesis and Dysregulated Sodium and Calcium Homeostasis with Increased Calcium Sparks. . J Cardiovasc Electrophysiol. .2011

140. 2011 Lin YK,Chen YC,Cheng CC,Lin FZ,Lin CI,Chen SA, Chen YJ.. Interactions of Aging and Hydrogen Peroxide on Pulmonary Vein Electrical Activity Implications in the Pathophysiology of Atrial Fibrillation. . Acta Cardiol Sin. .2011 ;(27):109-114

141. 2010 Chen YC,Kao YH,Huang CF,Cheng CC,Chen YJ,Chen SA. Heat stress responses modulate calcium regulations and electrophysiological characteristics in atrial myocytes . J Mol Cell Cardiol .2010 ;(48):781-788

142. 2010 CHEN-CHUAN CHENG,CHUN-FENG HUANG,Yao-Chang Chen,YUNG-KUO LIN,YU-HSUN KAO,YI-JEN CHEN, SHIH-ANN CHEN. Heat-Stress Responses Modulate Beta-Adrenergic Agonist and Angiotensin II Effects on the Arrhythmogenesis of Pulmonary Vein Cardiomyocytes. . Journal of Cardiovascular Electrophysiology .2010

143. 2010 Chen-Chuan Cheng,Nan-Hung Panb,Yao-Chang Chen,Hung-I Yeh,Cheng-I Lin,Shih-Ann Cheng,Yi-Jen Chen. Atherosclerosis modulates the electrophysiological effects of a peroxisome proliferator-activated receptor-gamma activator on pulmonary veins. . Int J Cardiol .2010

144. 2010 Lin YK,Lin FZ,Chen yc,Cheng CC,Lin CI,Chen YJ, Chen SA. Oxidative stress on pulmonary vein and left atrium arrhythmogenesis. . circulation journal .2010 ;(74):1547-1556

145. 2010 Lin YK,Chen YJ,Chen sa. Potential atrial arrhythmogenicity of adipocytes: implications for the genesis of atrial fibrillation. . Med Hypotheses. .2010 ;(74):1026-1029

146. 2010 Cheng CC,Pan NH,Chen YC,Yeh HI,Lin CI,Chen SA, Chen YJ.. Atherosclerosis modulates the electrophysiological effects of a peroxisome proliferator-activated receptor-gamma activator on pulmonary veins . Int J Cardiol .2010

147. 2010 Lin YK,Lu YY,Chen YC,Chen YJ,Chen SA. Nitroprusside modulates pulmonary vein arrhythmogenic activity. . J Biomed Sci .2010 ;(17):20

148. 2010 Pan NH,Chen YC,Kao YH,Chen YJ. Role of Glycogen Synthase Kinase3β/GATA-4 in Tumor Necrosis Factor-α-Regulated Sarcoplasmic Recticulum Ca(superscript 2+)-ATPase Expressions in Cardiomyocytes . Acta Cardiologica Sinca .2010 ;(26):179-183

149. 2010 Lin YK,Chen YJ,Chen SA. Potential atrial arrhythmogenicity of adipocytes: implications for the genesis of atrial fibrillation. . Med Hypotheses .2010 ;(74):1026-1029

150. 2010 Lee TI,Kao YH,Chen YC,Pan NH,Chen YJ. Oxidative stress and inflammation modulate peroxisome proliferator-activated receptors with regional discrepancy in diabetic heart. . Eur J Clin Invest .2010 ;(40):692-699

151. 2010 Huang JH,Lin YQ,Pan NH,Chen YJ. Aging modulates dispersion of ventricular repolarization in the very old of the geriatric population . Heart Vessels .2010 ;(25):500-508

152. 2010 Huang JH,Tsai JC,Hsu MI,Chen YJ. Cardiac conductive disturbance in patients with polycystic ovary syndrome . Gynecol Endocrinol .2010 ;(2612):883-888

153. 2010 Suenari K,Chen YC,Kao YH,Cheng CC,Lin YK,Chen YJ, Chen SA. Discrepant electrophysiological characteristics and calcium homeostasis of left atrial anterior and posterior myocytes Basic Res Cardiol . Basic Res Cardiol .2010

154. 2010 Lu YL,Chen YC,Kao YH,Wu TJ,Chen SA,Chen YJ. Extracellular Matrix of Collagen Modulates Intracellular . Journal of Cardiac Failure .2010

155. 2010 Kao YH,Chen YC,Cheng CC,Lee TI,Chen YJ,Chen SA. Tumor necrosis factor-alpha decreases sarcoplasmic reticulum Ca2+-ATPase expressions via the promoter methylation in cardiomyocytes . Crit Care Med .2010 ;(38):217-222

156. 2009 HU Y,Chen YC,Cheng CC,Higa S,Chen YJ,Chen SA. Fluvastatin reduces pulmonary vein spontaneous activity through nitric oxide pathway. . J Cardiovasc Electrophysiol .2009 ;(20):200-206

157. 2009 Pan NH,Tsao HM,Chang NC,Lee CM,Chen YJ,Chen SA. Dilated left atrium and pulmonary veins in patients with calcified coronary artery: a potential contributor to the genesis of atrial fibrillation. . J Cardiovasc Electrophysiol .2009 ;(20):153-158

158. 2009 Lee SH,Chen YC,Cheng CC,Higa SH,Chen YJ,Chen SA. HYPERTONICITY INCREASES RABBIT ATRIUM AND PULMONARY VEIN ARRHYTHMOGENESIS: A POTENTIAL CONTRIBUTOR TO THE GENESIS OF ATRIAL FIBRILLATION. . Clinical and Experimental Pharmacology and Physiology .2009 ;(36):419-424

159. 2009 Lee TI,Kao YH,Chen YC,Chen YJ. Proinflammatory cytokine and ligands modulate cardiac peroxisome proliferator-activated receptors . Eur J Clin Invest .2009 ;(39):23-30

160. 2009 Udyavar AR,Chen YC,Cheng CC,Higa S,Cheng YJ,Cheng SA. Cariporide (HOE642) attenuates lactic acidosis induced pulmonary vein arrhythmogenesis . Life Sci .2009 ;(85):19-25

161. 2009 Chen YC,Pan NH,Cheng CC,Higa S,Chen YJ,Chen SA. Heterogeneous expression of potassium currents and pacemaker currents potentially regulates arrhythmogenesis of pulmonary vein cardiomyocytes . J Cardiovasc Electrophysiol. .2009 ;(20):1639-1645

162. 2009 Yi-Jen Chen,Yao-Chang Chen,shih-Ann Chen,Cheng-I lin. Cardiac Cellular Electrophysiology, Voltage Clamp, and Patch Clamp . Acta cardiological Sinica .2009 ;(25):59-63

163. 2008 Udyavar AR,Chen YC,Chen YJ,Lin CI,Chen SA. Endothelin-1 modulates the arrhythmogenic activity of pulmonary veins. . J Cardiovasc Electroohysiol .2008 ;(19):285-292

164. 2008 Lee SH,Chen YC,Chen SY,Lin CI,Chen YJ,Chen SA.. Swelling activated chloride currents in the electrical activity of pulmonary vein cardiomyocytes . Eur J Clin Invest .2008 ;(38):17-23

165. 2008 Pan NH,Tsao HM,Chang NC,Chen YJ,Chen SA. Aging dilates atrium and pulmonary veins: implications for the genesis of atrial fibrillation. . Chest .2008 ;(133):190-196

166. 2008 Pan NH,Tsao HM,Chang NC,Chen YJ. Coronary calcium score from multislice computer tomography correlates with QT dispersion and LV wall thickness . Heart Vessel .2008 ;(23):155-160

167. 2008 CHANG SH,Chen YC,chiang SJ,Higa S,Cheng CC,Chen YJ, Chen SA. Increased Ca(2+) sparks and sarcoplasmic reticulum Ca(2+) stores potentially determine the spontaneous activity of pulmonary vein cardiomyocytes . Life Sci .2008 ;(83):284-292

168. 2008 Chen YJ,Chen YC,Wongcharoen W,Lin CI,Chen SA. Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes. . Br J Pharmacol .2008 ;(153):915-925

169. 2008 Udyavar AR,Chang SL,Tai CT,Lin YJ,Lo LW,Tuan TC, Tsao HM, Hsieh MH, Hu YF, Chiang SJ, Chen YJ, Wongcharoen W, Higa S, Ueng KC, Chen SA.. The important role of pulmonary vein carina ablation as an adjunct to circumferential pulmonary vein isolation. . Journal of cardiovascular electrophysiology .2008 ;(19):593-598

170. 2008 Hsu NW,Lin YJ,Tai CT,Kao T,Chang SL,Wongcharoen W, Lo LW, Udyavar AR, Hu YF, Tso HW, Chen YJ, Higa S, Chen SA.. Frequency analysis of the fibrillatory activity from surface ECG lead V1 and intracardiac recordings: implications for mapping of AF. . Europace .2008 ;(10):438-443

171. 2008 Lin YJ,Tai CT,Kao T,Chang SL,Wongcharoen W,Lo LW, Tuan TC, Udyavar AR, Chen YJ, Higa S, Ueng KC, Chen SA.. Consistency of complex fractionated atrial electrograms during atrial fibrillation. . Heart rhythm .2008 ;(5):406-412

172. 2007 Tuan TC,Chang SL,Tai CT,Lin YJ,Hu YF,Lo LW, Wongcharoen W, Udyavar AR,Chiang SJ, Chen YJ, Tsao HM, Ueng KC, Chen SA.. Impairment of the atrial substrates by chronic cigarette smoking in patients with atrial fibrillation. . Journal of cardiovascular electrophysiology .2007 ;(19):259-265

173. 2007 Chang SL,Tai CT,Lin YJ,Lo LW,Tuan TC,Udyavar AR, Tsao HM, Hsieh MH, Hu YF, Chiang SJ, Chen YJ, Wongcharoen W, Ueng KC, Chen SA.. Electrophysiological characteristics and catheter ablation in patients with paroxysmal supraventricular tachycardia and paroxysmal atrial fibrillation. . J Cardiovasc Electrophysiol .2007 ;(19):367-373

174. 2007 Lo LW,Tai CT,Lin YJ,Chang SL,Wongcharoen W,Hsieh MH, Tuan TC, Udyavar AR, Hu YF, Chen YJ, Chiang SJ, Tsao HM, Chen SA.. Characteristics and outcome in patients receiving multiple (more than two) catheter ablation procedures for paroxysmal atrial fibrillation. . J Cardiovasc Electrophysiol. .2007 ;(19):150-156

175. 2007 Chang SL,Tai CT,Lin YJ,Wongcharoen W,Lo LW,Lee KT, Chang SH, Tuan TC, Chen YJ, Hsieh MH, Tsao HM, Wu MH, Sheu MH, Chang CY, Chen SA.. The role of left atrial muscular bundles in catheter ablation of atrial fibrillation. . J Am Coll Cardiol .2007 ;(50):964-973

176. 2007 Chang SL,Tai CT,Lin YJ,Wongcharoen W,Lo LW,Tuan TC, Udyavar AR, ChangTuan TC, Udyavar AR, Chang SH, Tsao HM, Hsieh MH, Hu YF, Chen YJ, Chen SA.. Biatrial substrate properties in patients with atrial fibrillation. . J Cardiovasc Electrophysiol .2007 ;(18):1134-1139

177. 2007 Lo LW,Chen YC,Chen YJ,Wongcharoen W,Lin CI,Chen SA. Calmodulin kinase II inhibition prevents arrhythmic activity induced by alpha and beta adrenergic agonists in rabbit pulmonary veins. . Eur J Pharmacol .2007 ;(571):197-208

178. 2007 Lo LW,Tai CT,Lin YJ,Chang SL,Wongcharoen W,Hsieh MH, Tuan TC, Udyavar AR, Hu YF, Chen YJ, Tsao HM, Chen SA.. Mechanisms of recurrent atrial fibrillation: comparisons between segmental ostial versus circumferential pulmonary vein isolation. . J Cardiovasc Electrophysiol .2007 ;(18):803-807

179. 2007 Chang SL,Tai CT,Lin YJ,Wongcharoen W,Lo LW,Tuan TC, Udyavar AR, Chang SH, Tsao HM, Hsieh MH, Hu YF, Chen YJ, Chen SA.. The efficacy of inducibility and circumferential ablation with pulmonary vein isolation in patients with paroxysmal atrial fibrillation. . J Cardiovasc Electrophysiol .2007 ;(18):607-611

180. 2007 Lee PC,Hwang B,Chen SA,Tai CG,Chen YJ,Chiang CE, Meng CC. The results of radiofrequency catheter ablation of supraventricular tachycardia in children. . Pacing Clin Electrophysiol .2007 ;(30):655-661

181. 2007 Lin YJ,Tai CT,Lo LW,Udyavar AR,Chang SL,Wongcharoen W, Tuan TC, Hu YF, Chiang SJ, Chen YJ, Chen SA. Optimal electrogram voltage recording technique for detecting the acute ablative tissue injury in the human right atrium. . J Cardiovasc Electrophysiol .2007 ;(18):617-622

182. 2007 Lo LW,Tai CT,Lin YJ,Chang SL,Wongcharoen W,Chang SH, Hsieh MH, Tuan TC, Udyavar AR, Chen YJ, Tsao HM, Chen SA.. Progressive remodeling of the atrial substrate--a novel finding from consecutive voltage mapping in patients with recurrence of atrial fibrillation after catheter ablation. . J Cardiovasc Electrophysiol .2007 ;(18):258-265

183. 2007 Ong MG,Lee PC,Tai CT,Lin YJ,Hsieh MH,Chen YJ, Lee KT, Tsao HM, Kuo JY, Chang SL, Chen SA.. The electrophysiologic characteristics of atrioventricular nodal reentry tachycardia with eccentric retrograde activation. . Int J Cardiol .2007 ;(120):115-122

184. 2007 Lee SH,Chen YC,Chen YJ,Chang SL,Tai CT,Wongcharoen W, Yeh HI, Lin CI, Chen SA. Tumor Necrosis Factor-α Alters Calcium Handling and Increases Arrhythmogenesis of Pulmonary Vein Cardiomyocytes . Life Sciences .2007 ;(80):1806-1815

185. 2007 Chang SL,Chen YC,Chen YJ,Wangcharoen W,Lee SH,Lin CI, Chen SA. Mechanoelectrical feedback regulates the arrhythmogenic activity of pulmonary veins. . Heart .2007 ;(93):82-88

186. 2007 Wongcharoen W,Chen YC,Chen YJ,Lin CI,Chen SA. Effects of aging and ouabain on left atrial arrhythmogenicity . J Cardiovasc Electrophysiol .2007 ;(18):526-531

187. 2007 Chen YJ,Chen SA. Thoracic vein arrhythmias. . Circ J .2007 ;(supplA):A20-A25

188. 2007 Wongcharoen w,Chen YC,Chen YJ,Chen SY,Yeh HI,Lin CI, Chen SA. Aging increases pulmonary veins arrhythmogenesis and susceptibility to calcium regulation agents. . Heart Rhythm .2007 ;(4):1338-1349

189. 2006 Lee PC,Hwang B,Chen YJ,Tai CT,Chen SA,Chang CE. Electrophysiologic characteristics and radiofrequency catheter ablation in children with Wolff-Parkinson-White syndrome. . Pacing Clin Electrophysiol .2006 ;(29):490-495

190. 2006 Huang JL,Tai CT,Lin YJ,Huang BH,Lee KT,Higa S, Yuniadi Y, Chen YJ, Chang SL, Lo LW, Wongc. Substrate mapping to detect abnormal atrial endocardium with slow conduction in patients with atypical right atrial flutter . J Am Coll Cardiol .2006 ;(48):492-498

191. 2006 Wongcharoen W,Tsao HM,Wu MH,Tai CT,Chang SL,Lin YJ, Lo LW, Chen YJ, Sheu MH, Chang CY, Chen SA. Morphologic characteristics of the left atrial appendage, roof, and septum: implications for the ablation of atrial fibrillation. . J Cardiovasc Electrophysiol. .2006 ;(17):951-956

192. 2006 Chiang SJ,Tsao HM,Wu MH,Tai CT,Chang SL,Wongcharoen W, Lin YJ, Lo LW, Chen YJ, Sheu MH, Chang CY, Chen SA.. Anatomic characteristics of the left atrial isthmus in patients with atrial fibrillation: lessons from computed tomographic images. . J Cardiovasc Electrophysiol .2006 ;(17):1274-1278

193. 2006 Lee PC,Hwang B,Tai CT,Hsieh MH,Chen YJ,Chiang CE, Chen SA. The electrophysiological characteristics in patients with ventricular stimulation inducible fast-slow form atrioventricular nodal reentrant tachycardia. . Pacing Clin Electrophysiol .2006

194. 2006 Chen YJ,Chen YC,Tai CT,Yeh HI,Lin CI,Chen SA. Angiotensin II and angiotensin II receptor blocker modulate the arrhythmogenic activity of pulmonary veins. . Br J Pharmacol .2006 ;(147):12-22

195. 2006 Wongcharoen w,Chen YC,Chen YJ,Chang CM,Yeh HI,Lin CI, Chen SA. Effects of a Na+/Ca2+ exchanger inhibitor on pulmonary vein electrical . cardiovascular research .2006 ;(70):497-508

196. 2006 Chen YJ,Chen SA. Electrophysiology of Pulmonary Veins . J Cardiovasc Electrophysiol .2006 ;(17):220-224

197. 2005 Chen JC,Chen YJ,Chang WP,Christiani DC. Long driving time is associated with haematological markers of increased cardiovascular risk in taxi drivers . Occup Environ Med .2005 ;(62):890-894

198. 2005 Lee SH,Tai CT,Lee PC,Chiang CE,Cheng JJ,Ueng KC, Chen YJ, Hsieh MH, Tsai CF, Chiou CW, Yu. Electrophysiological characteristics of junctional rhythm during ablation of the slow pathway in different types of atrioventricular nodal reentrant tachycardia. . PACE .2005 ;(28):111-118

199. 2005 Chang SL,Lee SH,Tai CT,Chiang CE,Cheng JJ,Lin YJ, Hsieh MH, Lee KT, Tsao HM, Kuo JY, Chen YJ. Electrocardiographic and electrophysiologic characteristics of midseptal accessory pathways. . J Cardiovasc Electrophysiol .2005 ;(16):237-243

200. 2005 Huang BH,Wu MH,Tsao HM,Tai CT,Lee KT,Lin YJ, Hsieh MH, Lee SH, Chen YJ, Kuo JY, Chen SA. Morphology of the thoracic veins and left atrium in paroxysmal atrial fibrillation initiated by superior caval vein ectopy . J Cardiovasc Electrophysiol .2005 ;(16):411-417

201. 2005 Hsieh MH,Tai CT,Lss SH,Tsao HM,Lin YK,Huang JL, Chan P, Chen YJ, Kuo JY, Tuan TC, Hsu TL. Catheter ablation of atrial fibrillation versus atrioventricular junction ablation plus pacing therapy for elderly patients with medically refractory paroxysmal atrial fibrillation . J Cardiovasc Electrophysiol .2005 ;(16):456-471

202. 2005 Lee Sh,Tai CT,Hsieh MH,Taso HM,Lin YJ,Lin YJ. Predictors of non-pulmonary vein ectopic beats initiating paroxysmal atrial fibrillation: implication for catheter ablation . J Am Coll Cardiol .2005 ;(46):1054-1059

203. 2005 Lee SH,Chen YJ,Tai CT,Yeh HI,Cheng JJ,Hung CR, Chen SA.. Electrical remodeling of the canine superior vena cava after chronic rapid atrial pacing. . Basic Res Cardiol .2005 ;(100):14-21

204. 2004 Chen YC,Chen SA,Chen YJ,Tai CT,Chan P,Lin CI. T-type Calcium Current in Electrical Activity of Cardiomyocytes Isolated from Rabbit Pulmonary Vein. . J Cardiovasc Electrophysiol .2004 ;(15):567-571

205. 2004 Hsieh MH,Tai CT,Chiang CE,Tsai CF,Chen YJ,Chan P, Kuo YC, Lee SH, Ueng KC, Chen SA.. Double atrial potentials recorded in the coronary sinus in patients with Wolff-Parkinson-White syndrome: a possible mechanism of induced atrial fibrillation. . J Interv Card Electrophysiol .2004 ;(11):97-103

206. 2004 Chen YC,Chen SA,Chen YJ,Tai CT,Paul C,Lin CI. Effect of ethanol on the electrophysiological characteristics of pulmonary vein cardiomyocytes . Eur J Pharmacol .2004 ;(483):215-220

207. 2003 Chen YJ,Chen YC,Chan P,Lin CI,Chen SA. Temperature Regulates the Arrhythmogenic Activity of Pulmonary Vein Cardiomyocytes. . J Biomed Sci .2003 ;(10):535-543

208. 2003 Chen SA,Chen YJ,Yeh HI,Tai CT,Chen YC,Lin CI. Pathophysiology of the pulmonary vein as an atrial fibrillation initiator. Pacing Clin Electrophysio . PACE .2003 ;(26):1576-1582

209. 2003 Chen SA,Tai CT,Yeh HI,Chen YJ,Lin CI. Controversies in the mechanisms and ablation of pulmonary vein atrial fibrillation . PACE .2003 ;(26):1301-1307

210. 2003 Hsieh MH,Chen YJ,Chan P,Chen SA. Effects of magnesium sulfate and lidocaine on cisapride-induced ventricular proarrhythmia in canine heart . Acta Cardiolgica Sinica .2003 ;(19):95-100

211. 2003 Yeh HI,Lai YJ,Lee YC,Chen YJ,Chen YC,Chen CC., Chen SA., Lin CI,Tsai CH. Differential Expression of Connexin43 Gap Junctions in Cardiomyocytes Isolated From the Canine Thoracic Veins. . J Histochem Cytochem .2003 ;(51):259-266

212. 2002 Chen YJ, Chen SA, Chen YC, Yeh HI, Chang MS, Lin CI.. Electrophysiology of single cardiomyocytes isolated from rabbit pulmonary veins: implication in initiation of focal atrial fibrillation. . Basic Res Cardiol .2002 ;(97):26-34

213. 2002 Chen YC, Chen SA, Chen YJ, Chang MS, Chan P, Lin CI.. Effects of thyroid hormone on the arrhythmogenic activity of pulmonary vein cardiomyocytes. . J Am Coll Cardiol .2002 ;(39):366-372

214. 2002 Chen YJ, Chen YC, Yeh HI, Lin CI, Chen SA.. Electrophysiology and arrhythmogenic activity of single cardiomyocytes from canine superior vena cava. . Circulation .2002 ;(105):2679-2685

215. 2002 Chen YJ*, Chen YC, Lin CI, Chen SA.. Thyroid hormone and arrhythmogenic activity. . J Am Coll Cardiol .2002

216. 2002 Lee TI, Lin CC, Chan TS, Chan P, Chen YJ. Vetricular dysfunction in a patient of Plummer’s Disease: A Case Report. . Heart Vessel .2002 ;(16):118-120

217. 2001 12. Chen YJ, Tsai, CF, Chiou CW, Chan P, Chen SA.. Effect of Nitric Oxide on Strophanthidin-induced Ventricular Tachycardia. . Pharmacology .2001 ;(62):213-217

218. 2001 Chen YJ, Chen SA, Chen YC, Yeh HI, Paul C, Chang MS, Lin CI.. Effects of rapid atrial pacing on the arrhythmogenic activity of single cardiomyocytes from pulmonary veins: implication in initiation of atrial fibrillation. . Circulation .2001 ;(104):2849-2854

219. 2000 Chen Y.J., Tai C.T., Hsieh M.H., Tsai C.F., Lin W.S., Chen S.A. Dependence of electrogram duration in right posteroseptal atrium and atrium-pulmonary vein junction on pacing site: mechanism and implications regarding atrioventricular nodal reentrant tachycardia and paroxysmal atrial fibrillation. . J Cardiovasc Electrophysiol .2000 ;(11):506-515

220. 2000 Chen YJ, Chen SA, Chang MS, Lin CI.. Arrhythmogenic activity of cardiac muscle in pulmonary veins of the dog: implication for the genesis of atrial fibrillation. . Cardiovasc Res .2000 ;(48):265-273

221. 2000 Chen YJ, Chen YC, Chen SA, Chan P, Lin CI.. Autonomic agentys in the genesis of tachyarrhythmias in dog pulmonary veins. . J Jpn Electrophysiol .2000 ;(20):s46-s49

222. 2000 Liu JC, Chow JM. Tsai MF, Hsieh MH, Chen YJ, Chan P.. Down-regulation of superoxide dismutase gene expression in cultured rat aortic smooth muscle cells (A7r5) after long-term incubation with vitamin C . Acta Cardiol Sin .2000 ;(16):209-216

223. 2000 Chou TM, Chen YJ, Chan P.. Cardioprotective effects of triglyceride isolated from the herb sanchi (panax pseudogineseng) . N Tpe J Med .2000 ;(2):87-92

224. 1999 Chen YJ, Chen SA, Tai CT, Chiang CE, Chang MS and Hong CY.. Effect of trilinolein on strophanthidin-induced ventricular tachycardia in guinea pigs. . Pharmacology .1999 ;(58):15-23

225. 1999 Chen SA, Tai CT, Yu WC, Chen YJ, Tasi CF, Hsieh MH, Chen CC, Prakash VS, Ding TA and Chang MS. Right atrial focal atrial fibrillation: electrophysiologic characteristics and radiofrequency catheter ablation. . J Cariovasc. Electrophysiol. .1999 ;(10):328-335

226. 1999 Chan P, Chiu WT, Chen YJ, Wu PJ and Chang JT. Calcium influx inhibition: possible mechanism of the negative effect of tetrahydropalmatine on left ventricular pressure in isolated rat heart. . Planta Med. .1999 ;(65):340-342

227. 1999 Lee SH, Tai CT, Yu WC, Chen YJ, Hsieh MH, Tsai CF, Chang MS and Chen SA. Effects of radiofrequency catheter ablation on quality of life in patients with atrial flutter. . Am. J. Cardiol. .1999 ;(84):278-283

228. 1999 Chen YJ, Hsieh MH, Chiou CW and Chen SA. Electropharmacologic characteristics of ventricular proarrhythmia induced by ibutilide. . J. Cardiovasc. Pharmacol. .1999 ;(34):237-247

229. 1999 Chen YJ, Lee SH, Hsieh MH, Hsian CJ, Yu WC, Chiou CW and Chen SA. Effect of 17b-estradiol on tachycardia-induced changes of atrial refractoriness and cisapride-induced ventricular arrhythmia. . J. Cardiovasc. Electrophysiol. .1999 ;(10):587-598

230. 1999 Chen YJ, Tai CT, Chiou CW, Wen ZC, Chan P, Lee SH and Chen SA. Inducibility of atrial fibrillation atrioventricular pacing with varying intervals: role of atrial electrophysiology and autonomic nervous system. . J Cardiovas. Electrophysiol. (accepted). .1999

231. 1999 Tsai CF, Tai CT, Yu WC, Chen YJ, Hsieh MH, Chiang CE, Ding YA, Chang MS and Chen SA. Is 8-mm more effective than 4-mm tip electrode catheter for ablation of typical atrial flutter? . Circulation .1999 ;(100):768-771

232. 1998 Chen YJ, Chen SA, Tai CT, Wen ZC, Feng AN, Ding YA and Chang MS. Role of atrial electrophysiology and autonomic nervous system in patients with supraventricular tachycardia and paroxysmal atrial fibrillation. . J. Am. Coll. Cardiol. .1998 ;(32):732-738

233. 1998 Tai CT, Chen SA, Chiang CE, Lee SH, Wen ZC, Huang JL, Chen YJ, Yu WC, Feng AN, Lin YJ, Ding YA and Chang MS. Long-term outcome of radiofrequency catheter ablation for typical atrial flutter: risk prediction of recurrent arrhythmias. J. Cardiovasc. . Electrophysiol. .1998 ;(9):115-121

234. 1998 Tai CT, Chen SA, Feng AN, Chen YJ and Chang MS. Electrophysiological effects of Class I and class III antiarrhythmia drugs on typical atrial flutter. Insight into the mechanism of termination. . Circulation .1998 ;(97):1935-1945

235. 1998 Hsieh MH, Chen SA, Tai CT, Yu WC, Chen YJ and Chang MS. Absence of junctional rhythm during successful slow pathway ablation in patients with atrioventricular nodal reentrant tachycardia. . Circulation .1998 ;(98):2296-2300

236. 1998 Chan P, Xu DY, Liu JC, Chen YJ, Tomlinson B, Huang WP and Cheng JT. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. . Life Science .1998 ;(63):1679-1684

237. 1998 Chan P, Huang TY, Chen YJ, Huang WP and Liu YC. Randomized double-blind placebo controlled study of the safety and efficacy of vitamine B complex in the treatment of nocturnal leg cramps in elderly patients with hypertension. . J. Clin. Pharmacol. .1998 ;(38):1151-1154

238. 1998 Chen YJ, Chen SA, Tai CT, Yu WC, Feng AN, Ding YA and Chang MS. Electrophysiologic characteristics of a dilated atrium in patients with paroxysmal atrial fibrillation and atrial flutter. . J. Interventional Cardiac Electrophysiology .1998 ;(2):181-186

239. 1997 Tai CT, Chen SA, Chiang CE, LeeSH, Wen ZC, Chen YJ, Yu WC, Huang JL and Chang MS. Identification of fiber orientation in left free-wall accessory pathways implication for radiofrequency ablation. . J. Interventional Cardiac Electrophysiology .1997 ;(1):235-240

240. 1997 Yu WC, Chen SA, Tai CT, Chiang CE, Lee SH, Chiou CW, Ueng KC, Wen ZC, Chen YJ, Huang JL, Feng AN and Chang MS. Radiofrequency catheter ablation of slow pathway in 760 patients with atrioventricular nodal reentrant tachycardia--long-term results. . Chin. Med. J. (Taipei) .1997 ;(59):71-77

241. 1997 Chen YJ, Chen SA, Tai CT, Chiang CE, Lee SH, Chiou CW, Ueng KC, Wen ZC, Yu WC, Huang JL, Feng AN and Chang MS. Long-term results of radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome. . Chin. Med. J. (Taipei) .1997 ;(59):78-87

242. 1997 Lee SH, Chen SA, Tai CT, Chiang CE, Wen ZC, Chen YJ, Yu WC, FongAN, Huang JL, Cheng JJ and Chang MS. atrioventricular nodal reentrant tachycardia in patients with a prolonged AH interval during sinus rhythm: clinical feathures, electrophysiologic characteristics and results of radiofrequency ablation. . J. Interventional Cardiac Electrophysiology .1997 ;(1):305-310

243. 1997 Lee SH, Chen SA, Chiang CE, Tai CT, Wen ZC, Ueng KC, Chiou CW, Chen YJ, Yu WC, Huang JL, Cheng JJ and Chang MS. Results of radiofrequency ablation in patients with clinically documented, but noninducible, atrioventricular node reentrant tachycardia and orthodromic atrioventricular reciprocating tachycardia. . Am. J. Cardiol. .1997 ;(79):974-978

244. 1997 Lee SH, Chen SA, Tai CT, Chiang CE, Wen ZC, Chen YJ, Yu WC, Fong AN, Huang JL, Cheng JJ and Chang MS. Atrioventricular node reentrant tachycardia in patients with a long fast pathway effective refractory period: clinical features, electrophysiologic characteristics, and results of radiofrequency ablation. . Am. Heart J. .1997 ;(134):387-394

245. 1997 Lee SH, Chen SA, Tai CT, Chiang CE, Wen ZC, Chen YJ, Yu WC, Huang JL, Feng AN, Cheng JJ and Chang MS. Comparisons of oral propafenone and sotalol as an initial treatment in patients with symptomatic paroxysmal atrial fibrillation. . Am. J. Cardiol. .1997 ;(79):905-908

246. 1997 Lee SH, Chen SA, Tai CT, Chiang CE, Wen ZC, Ueng KC, Chiou CW, Chen YJ, Yu WC, Huang JL, Cheng JJ and Chang MS. Electrophysiologic characteristics and radiofrequency catheter ablation in atrioventricular node reentrant tachycardia with second-degree atrioventricular block. . J. Cardiovasc. Electrophysiol. .1997 ;(8):502-511

247. 1997 Yu WC, Chen SA, Chiang CE, Tai CT, Lee SH, Chiou CW, Ueng KC, Wen ZC, Chen YJ, Huang JL, Feng AN and Chang MS. Effect of high intensity drive train stimulation on dispersion of atrial refractoriness: role of autonomic nervous system. . J. Am. Coll. Cardiol. .1997 ;(29):1000-1006

248. 1997 Yu WC, Chen SA, Tai CT, Lee SH, Chiang CE, Wen ZC, Chiou CW, Ueng KC, Chen YJ, Huang JL and Chang MS. Electrophysiologic characteristics and radiofrequency catheter ablation of fast-slow form atrioventricular nodal reentrant tachycardia. . Am. J. Cardiol. .1997 ;(79):683-686

249. 1997 Tai CT, Chen SA, Chiang CE, Lee SH, Ueng KC, Wen ZC, Chen YJ, Yu WC, Huang JL, Chiou CW and Chang MS. Electrophysiologic characteristics and radiofrequency catheter ablation in patients with clockwise atrial flutter. J Cardiovasc. . Electrophysiol. .1997 ;(8):24-34

250. 1997 Tai CT, Chen SA, Chiang CE, Lee SH, Ueng KC, Wen ZC, Huang JL, Chen YJ, Yu WC, Feng AN, Chiou CW and Chang MS. Characterization of low right atrial isthmus as the slow conduction zone and pharmacological target in typical atrial flutter. . Circulation. .1997 ;(96):2601-2611

251. 1997 Tai CT, Chen SA, Chiang CE, Lee SH, Wen ZC, Chiou CW, Ueng KC, Chen YJ, Yu WC and Chang MS. A new electrocardiographic algorithm using retrograde P waves for differentiating atrioventricular node reentrant tachycardia from atrioventricular reciprocating tachycardia mediated by concealed accessory pathway. . J. Am. Coll. Cardiol. .1997 ;(29):394-402

252. 1997 Tai CT, Chen SA, Chiang CE, Lee SH, Wen ZC, Chiou CW, Ueng KC, Chen YJ, Yu WC, Huang JL and Chang MS. Complex electrophysiological characteristics in atrioventricular nodal reentrant tachycardia with continuous atrioventricular node function curves. . Circulation .1997 ;(95):2541-2547

253. 1997 Tsai CF, Chen SA, Chiang CE, Tai CT, Lee SH, Wen ZC, Chen YJ, Yu WC, Huang JL, Feng AN and Chang MS. Radiofrequency ablation-induced asystole during transaortic approach for a left anterolateral accessory pathway: a Bezold-Jarisch-like phenomenon. . J. Cardiovasc. Electrophysiol. .1997 ;(8):694-699

254. 1996 Yu WC, Chen SA, Chiagn CE, Tai CT, Lee SH, Chiou CW, Ueng KC, Wen ZC, Chen YJ, Huang JL and Chang MS. Effects of isoproterenol in facilitating induction of slow-fast atrioventricular nodal reentrant tachycardia. . The American Journal of Cardiology .1996 ;(78):1299-1302

255. 1996 Chen A, Tai CT, Chiang CE, Lee SH, Wen ZC, Chiou CW, Ueng KC, Chen YJ, Yu WC, Huang JL and Chang MS. Electrophysiologic characteristics, electropharmacologic responses and radiofrequency ablation in patients with decremental accessory pathway. . J. Am. Coll. Cardiol. .1996 ;(28):732-737

256. 1996 Chiou CW, Chen SA, Tai CT, Chiang CE, Lee SH, Ueng KC, Wen ZC, Yu WC, Chen YJ, Huang JL, Chen CY and Chang MS. Co-existence of atrial tachycardia and common atrial flutter: electrophysiologic characteristics and radiofreqency catheter ablation. . International Journal of Cardiology .1996 ;(55):79-85

257. 1996 Chen SA, Tai CT, Lee SH, Chiagn CE, Wen ZC, Chiou CW, Ueng KC, Chen YJ, Yu WJ, Huang JL and Chang MS. Electrophysiologic characteristics and anatomical complexities of accessory atrioventricular pathways with successful ablation of anterograde and retrograde conduction at different sites. . Journal of Cardivascular Electrophysiology .1996 ;(7):907-915

258. 1996 Huang JH, Chen SA, Tai CT, Chiang CE, Lee SH, Chiou CW, Ueng KC, Wen ZC, Yu WC, Chen YJ and Chang MS. Long-term results of radiofrequency catheter ablation in patients with multiple accessory pathways. . The American Journal of Cardiology .1996 ;(78):1375-1379

259. 1996 Chen YJ, Chen SA, Chiang CE, Tai CT, Lee SH, Chiou CW, Ueng KC, Wen ZC, Yu WC and Chang MS. Dual AV node pathway physiology in patients with Wolff-Parkinson-White Syndrome. . International Journal of Cardiology .1996 ;(56):275-281

260. 1996 Tai CT, Chen SA, Chiang CE, Lee SH, Chiou CW, Ueng KC, Wen ZC, Chen YJ and Chang MS. Multiple anterograde atrioventricular node pathways inpatients with atrioventricular node reentrant tachycardia. . JACC .1996 ;(28):725-731

261. 1996 Ueng KC, Chen SA, Chiang CE, Tai CT, Lee SH, Chiou CW, Wen ZC, Tseng CJ, Chen YJ, Yu WC, Chen CY and Chang MS. . Journal of Cardiovascular Electrophysiology .1996 ;(7):1017-1024

262. 1996 Wen ZC, Chen SA, Chiang CE, Tai CT, Lee SH, Chen YJ, Chiou CW, Ueng KC and Chang MS. Efficiency of heating during radiofrequency catheter ablation of accessory atrioventricular pathways. . International Journal of Cardiology .1996 ;(53):279-283

263. 1996 Wen ZC, Chen SA, Chiang CE, Tai CT, Lee SH, Chen YZ, Yu WC, Huang JL and Chang MS. Temperature and impedance monitoring during radiofrequency catheter ablation of slow AV node pathway in patients with atrioventricular node reentrant tachycardia. . International Journal of Cardiology .1996 ;(57):257-263

264. 1996 Wen ZC, Chen SA, Tai CT, Chiang CE, Lee SH, Chen YJ, Yu WC, Huang JL and Chang MS. Temperature monitoring in radiofrequency catheter ablation of atrial flutter using the linear ablation technique. . Journal of Cardiovascular Electrophysiology .1996 ;(7):1050-1057

書籍 Book


1. 2004 Chen YJ,Chen YC,Chen LI,Chen SA. Ionic Currents and Mechanisms of Ectopy from Thoracic Vein. . .2004

研究計畫

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104 ZFHX3基因對心房電生理調控及分子生物機轉研究與心房顫動之關聯性(3/3)
補助單位
科技部
計畫名稱
103 秋水仙素對於心房肌細胞之鈣離子恆定及電生理特性調控的影響
補助單位
奇美醫療財團法人奇美醫院
計畫名稱
103 ZFHX3基因對心房電生理調控及分子生物機轉研究與心房顫動之關聯性-徐榮杰(博)
補助單位
科技部
計畫名稱
103 脂肪細胞對心房細胞之離子及心電生理變化調控之研究(4/4)
補助單位
科技部
計畫名稱
103 ZFHX3基因對心房電生理調控及分子生物機轉研究與心房顫動之關聯性(2/3)
補助單位
行政院國家科學委員會
計畫名稱
102 纖維母細胞生長因子23誘發心房心律不整及鈣離子調控之作用機轉研究
補助單位
奇美醫療財團法人奇美醫院
計畫名稱
102 脂肪細胞對心房細胞之離子及心電生理變化調控之研究(3/4)
補助單位
行政院國家科學委員會
計畫名稱
102 ZFHX3基因對心房電生理調控及分子生物機轉研究與心房顫動之關聯性(1/3)
補助單位
行政院國家科學委員會
計畫名稱
102 脂肪細胞對心房細胞之離子及心電生理變化調控之研究(3-4)
補助單位
科技部
計畫名稱
102 脂肪細胞對心房細胞之離子及心電生理變化調控之研究(4/4)
補助單位
科技部
計畫名稱
102 ZFHX3基因對心房電生理調控及分子生物機轉研究與心房顫動之關聯性(1-3)
補助單位
科技部
計畫名稱
102 ZFHX3基因對心房電生理調控及分子生物機轉研究與心房顫動之關聯性(2/3)
補助單位
科技部
計畫名稱
102 ZFHX3基因對心房電生理調控及分子生物機轉研究與心房顫動之關聯性-徐榮杰(博)
補助單位
科技部
計畫名稱
101 類固醇與環氧化酵素抑制劑調控脂多糖對肺靜脈及心房之電生理影響
補助單位
奇美醫療財團法人奇美醫院
計畫名稱
101 脂肪細胞對心房細胞之離子及心電生理變化調控之研究
補助單位
行政院國家科學委員會
計畫名稱
101 Apelin對左心房與肺靜脈心肌細胞之電生理特性及鈣離子調控與心房顫動之致病機制研究
補助單位
行政院國家科學委員會
計畫名稱
100 棕櫚酸甲基酯(PAME)對肺靜脈和左心房的影響
補助單位
奇美醫療財團法人奇美醫院
計畫名稱
100 脂肪細胞對心房細胞之離子及心電生理變化調控之研究
補助單位
行政院國家科學委員會
計畫名稱
100 Apelin對左心房與肺靜脈心肌細胞之電生理特性及鈣離子調控與心房顫動之致病機制研究
補助單位
行政院國家科學委員會
計畫名稱
99 氧化壓力與抗氧化物對心房及肺靜脈心肌細胞之電生理與鈣離子調控之細胞與分子生物機轉
補助單位
行政院國家科學委員會
計畫名稱
99 Apelin對左心房與肺靜脈心肌細胞之電生理特性及鈣離子調控與心房顫動之致病機制研究
補助單位
行政院國家科學委員會
計畫名稱
98 Statins (3-hydroxyl-3 -methyl coenzyme A (HMG-CoA) reductase inhibitors)對於HL-1心房細胞之熱休克蛋白與鈣離子調控的分子生理機制
補助單位
奇美醫療財團法人奇美醫院
計畫名稱
98 心血管疾病與婦女健康
補助單位
台北市立萬芳醫院委託財團法人私立臺北醫學大學辦理
計畫名稱
98 多囊性卵巢症候群對內皮前驅細胞功能的影響
補助單位
台北市立萬芳醫院委託財團法人私立臺北醫學大學辦理
計畫名稱
98 性別差異於心房及肺靜脈心肌之電生理特性, 鈣離子調控與心房顫動之病理生理機轉(2-3)
補助單位
行政院國家科學委員會
計畫名稱
98 氧化壓力與抗氧化物對心房及肺靜脈心肌細胞之電生理與鈣離子調控之細胞與分子生物機轉
補助單位
行政院國家科學委員會
計畫名稱
97 氧化性壓力對於心房細胞HL-1鈣離子調控的分子生理機制
補助單位
奇美醫療財團法人奇美醫院
計畫名稱
97 性別差異於心房及肺靜脈心肌之電生理特性, 鈣離子調控與心房顫動之病理生理機轉(2-3)
補助單位
行政院國家科學委員會
計畫名稱
96 性別差異於心房及肺靜脈心肌之電生理特性, 鈣離子調控與心房顫動之病理生理機轉
補助單位
行政院國家科學委員會
計畫名稱
96 氧化壓力與抗氧化物對心房及肺靜脈心肌細胞之電生理與鈣離子調控之細胞與分子生物機轉
補助單位
行政院國家科學委員會
計畫名稱
95 調控鈣離子釋放(Ryanodine 接受器)對肺靜脈心肌細胞之鈣離子恆定、鈣離子亮點與引發心律不整活性之作用
補助單位
行政院國家科學委員會
計畫名稱
94 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) 還原酵素阻斷素, statins對肺靜脈及心房心肌細胞之電生理與心律不整作用
補助單位
行政院國家科學委員會
計畫名稱
93 心肥大對肺靜脈及心房肌細胞之電生理作用與心房顫動之關聯性
補助單位
行政院國家科學委員會
計畫名稱
93 細胞擴張引發之外向氯離子流於肺靜脈心肌細胞之心律不整作用
補助單位
新光醫療財團法人新光吳火獅紀念醫院
計畫名稱
92 鈉鈣離子交換在肺靜脈及上腔靜脈引發心房顫動之角色　　
補助單位
財團法人台灣基督長老教會馬偕紀念社會事業基金會馬偕紀念醫院
計畫名稱
92 腫瘤壞死因子對肺靜脈心肌細胞之促心律不整及電生理作用
補助單位
行政院國家科學委員會
計畫名稱
92 腫瘤壞死因子對肺靜脈心肌細胞之促心律不整及電生理作用
補助單位
新光醫療財團法人新光吳火獅紀念醫院
計畫名稱
91 酒精作於肺靜脈心肌細胞之促心律不整的機轉
補助單位
行政院國家科學委員會
計畫名稱
90 上腔靜脈心肌細胞之電生理特性，引發心律不整之活性，與陣發性心房纖動之關聯
補助單位
臺北醫學大學
計畫名稱
89 雙心室電刺激對心室再極化及藥物引發心律不整的影響
補助單位
臺北醫學大學