何秀娥(Ho, Hsiu-O) 教授

Email
hsiuoho@tmu.edu.tw
現   職
藥物科學學科 教授

學經歷

學 歷

畢業學校與學位[修業時間]
私立臺北醫學院藥學研究所 博士
1988/09/01~1992/06/01
私立臺北醫學院藥學研究所 碩士
1983/09/01~1985/06/01
私立臺北醫學院藥學系 學士
1978/09/01~1983/06/01

本校學術經歷

任職單位與職稱[起迄時間]
藥物科學學科教授
2012/02/01~
藥學系教授
2003/08/01~2012/01/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
無資料!

專長與研究領域

學門領域
藥物分析 (Drug analysis)
藥物傳遞系統 (Drug delivery system)
學術專長
藥物分析 (Drug analysis)
藥物傳遞系統 (Drug delivery system)

論文著作

清冊下載


1. 2023 Synergistic Combination of Irinotecan and Rapamycin Orally Delivered by Nanoemulsion for Enhancing Therapeutic Efficacy of Pancreatic Cancer . Pharmaceutics .2023 ;(15):473

2. 2022 Wei-Jie Cheng,Kuo-Hsiang Chuang, Yu-Ju Lo,Michael Chen,Yi-Jou Chen,Steve R, Hsiu-O Ho, Shyr-Yi Lin, Ming-Thau Sheu. Bispecific T-cell Engagers Non-covalently Decorated Drug-loaded PEGylated Nanocarriers for Cancer Immunochemotherapy . Journal of Controlled Release .2022 ;(344):235-248

3. 2022 Po-Yu Chou,Shyr-Yi Lin,Yi-No Wu, Chia-Yu Shen,Ming-Thau Sheu,Hsiu-O Ho. Glycosylation of OVA antigen-loaded PLGA nanoparticles enhances DC-targeting for cancer vaccination . Journal of Controlled Release .2022 ;(351):970-988

4. 2021 Pu-Sheng Wei,Yi-Jou Chen ,Shyr-Yi Lin,Kuo-Hsiang Chuang, Ming-Thau Sheu,Hsiu-O Ho. In situ subcutaneously injectable thermosensitive PEG-PLGA diblock and PLGA-PEG-PLGA triblock copolymer composite as sustained delivery of bispecific anti-CD3 scFv T-cell/anti-EGFR Fab Engager (BiTEE) . Biomaterials .2021 ;(278):1-12

5. 2021 Wen-Ting Cheng,Hsiu-O Ho,Shyr-Yi Lin,Der-Zen Liu,Ling-Chun Chen,Ming-Thau Sheu. Carfilzomib and Paclitaxel Co-Loaded Protein Nanoparticles an Effective Therapy Against Pancreatic Adenocarcinomas. . International Journal of Nanomedicine .2021 ;(2021):6825-6841

6. 2020 Preparation and characterization of chemically TEMPO-oxidized and mechanically disintegrated sacchachitin nanofibers (SCNF) for enhanced diabetic wound healing . Carbohydrate Polymers .2020 ;(229):115507-115516

7. 2020 Hong-Liang Lin,Ling-Chun Chen,Wen-Tian Cheng,Wei-Jie Cheng,Hsiu-O Ho,Ming-Thau Sheu. Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (sfGRDDS) for Enhanced Oral Bioavailability of Nilotinib . Pharmaceutics .2020 ;(12):137-149

8. 2020 Hong-Liang Lin,Ting-Huan Wu,Hsiu-O Ho,Fang-Ching Chao,Meng-Huang Wu,Der-Zen Liu, Ling-Chun Chen, Ming-Thau Sheu. TEMPO-Oxidized Sacchachitin Nanofibers (TOSCNFs) Combined With Platelet-Rich Plasma (PRP) for Management of Dry Eye Syndrome . Int J Nanomedicine .2020 ;(15):1721-1730

9. 2020 Chien-Ming Hsieh,Weu Wang,Ying-Hsuan Chen,Pu-Sheng Wei,Yu-Hsuan Liu,Ming-Thau Sheu, Hsiu-O Ho. A Novel Composite Hydrogel Composed of Formic Acid-Decellularized Pepsin-Soluble Extracellular Matrix Hydrogel and Sacchachitin Hydrogel as Wound Dressing to Synergistically Accelerate Diabetic Wound Healing . Pharmaceutics .2020 ;(12):538-556

10. 2019 In situ chemically crosslinked injectable hydrogels for the subcutaneous delivery of trastuzumab to treat breast cancer . Acta Biomaterialia .2019 ;(0):1-11

11. 2018 Chia-Yu Su,Jun-Jen Liu,Yuan-Soon Ho,Yi-You Huang,Vincent Hung-Shu Chang,Der-Zen Liu, Ling-Chun Chen, Hsiu-O Ho, Ming-Thau Sheu. Development and Characterization of Docetaxel-Loaded Lecithin-Stabilized Micellar Drug Delivery System (LsbMDDs) for Improving the Therapeutic Efficacy and Reducing Systemic Toxicity . European Journal of Pharmaceutics and Biopharmaceutics .2018 ;(123):9-19

12. 2018 Chia-En Chang,Chien-Ming Hsieh,Ling-Chun Chen,Chia-Yu Su,Der-Zen Liu,Hua-Jing Jhan, Hsiu-O Ho#and Ming-Thau Sheu#. Novel Application of Pluronic Lecithin Organogels (PLOs) for the Local Delivery of a Synergistic Combination of Docetaxel and Cisplatin to Improve the Therapeutic Efficacy against Ovarian Cancer . Drug Delivery .2018 ;(25):632-634

13. 2018 Chia-Yu Su,Hsiu-O Ho,Ying-Chen Chen,Yu-Ting Yu,Der-Zen Liu,Fang-Ching Chao, Ming-Thau Sheu. Complex Hydrogels Composed of Chitosan with Ring-opened Polyvinyl Pyrrolidone as a Gastroretentive Drug Dosage Form to Enhance the Bioavailability of Bisphosphonates . Scientific Reports .2018 ;(8):8092-8104

14. 2018 Chia-Yu Su,Michael Chen,Ling-Chun Chen,Yuan-Soon Ho,Hsiu-O Ho,hyr-Yi Lin, Kuo-Hsiang Chuang, Ming-Thau Sheu. Bispecific antibodies (Anti-mPEG/Anti-Her2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-Overexpressing tumors . Drug Delivery .2018 ;(25):1066-1079

15. 2018 Li-Ming Yang Kuo,Pei-Yi Tseng,Yu-Chi Lin,Chia-Ching Liaw,Li-Jie, Zhang,Ken-Chang Tsai, Zhi-Hu Lin, Hsiu-O Ho, Yao-Haur Kuo. New hirsutinolide-type sesquiterpenoids from Vernonia cinerea inhibit nitric oxide production in LPS-stimulated RAW264.7 cells . Planta Medica .2018 ;(84):1348-1354

16. 2018 Chia-En Chang,Chien-Ming Hsieh,Sheng-Chin Huang,Chia-Yu Su,Ming-Thau Sheu,Hsiu-O Ho. Lecithin-Stabilized Polymeric Micelles (LsbPMs) for Delivering Quercetin: Pharmacokinetic Studies and Therapeutic Effects of Quercetin Alone and in Combination with Doxorubicin (Accepted for publication) . Scientific Reports .2018 ;(0):1-10

17. 2017 Ming-Thau Sheu,Chen-Yuan Wu,Chia-Yu Su. Determination of total and unbound docetaxel in plasma by ultrafiltration and UPLC-MS/MS: Application to pharmacokinetic studies . Scientific Reports .2017 ;(7):14609-14617

18. 2017 Tzu-Pin Li,Wan-Ping Wong,Ling-Chun Chen,Chia-Yu Su,Lih-Geeng Chen,Der-Zen Liu, Hsiu-O Ho, Ming-Thau Sheu. Physical and Pharmacokinetic Characterizations of transResveratrol (t-Rev) Encapsulated with Self-Assembling Lecithin based Mixed Polymeric Micelles (saLMPMs) . Scientific Reports .2017 ;(7):1-11

19. 2016 Ling-Chun Chen,Yin-Chen Chen,Chia-Yu Su,Wan-Ping Wong,Ming-Thau Sheu. Development and Characterization of Lecithin-based Self-assembling Mixed Polymeric Micellar (saMPMs) Drug Delivery Systems for Curcumin . Scientific Reports .2016 ;(6):1-11

20. 2016 Chen LC,Chen TC,Su CY,Hong CS,Ho HO,Sheu MT. Development and Characterization of Self-assembling Lecithin-based Mixed Polymeric Micelles Containing Quercetin in Cancer Treatment and an in Vivo Pharmacokinetic Study(accepted for publication) . International Journal of Nanomedicine .2016 ;(0):0-0

21. 2016 Liao CH,Wu YN,Chen BH,Lin YH,Ho HO,Chiang HS. Neuroprotective effect of docosahexaenoic acid nanoemulsion on erectile function in a rat model of bilateral cavernous nerve injury . Scientific Report .2016 ;(14):33040-33047

22. 2016 Sheu MT,Jhan HJ,Su CY,Chen LJ,Chang CE,Liu DZ, Ho HO. Co-delivery of doxorubicin-containing thermosensitive hydrogels incorporated with docetaxel-loaded mixed micelles to enhance local cancer therapy . Colloids and Surfaces B: Biointerfaces .2016 ;(143):260-270

23. 2016 Sheu MT,Hsieh CM,Chen RN,Chou PU,Ho HO. Rapid-onset sildenafil sublingual drug delivery systems: in vitro evaluation and in vivo pharmacokinetic studies in rabbits (Accepted for publication) . Journal of Pharmaceutical Sciences .2016 ;(0):0-0

24. 2015 Chen YC,Su CY,Than JH,Ho HO,Sheu MT. Physical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles. . Int. J. Nanomedicine .2015 ;(10):7265-7274

25. 2015 Chen YC,Ho HO,Liu DZ,Siow WS,Sheu MT. Swelling/Floating Capability and Drug Release Characterizations of Gastroretentive Drug Delivery System Based on a Combination of Hydroxyethyl Cellulose and Sodium Carboxymethyl Cellulose. . PLOS ONE .2015 ;(10):1-7

26. 2015 Chen YC,Ho HO,Chiu JD,Sheu MT. Physical and Dissolution Characterization of Cilostazol Solid Dispersions Prepared by Hot Melt Granulation (HMG) and Thermal Adhesion Granulation (TAG) Methods. . International Journal of Pharmaceutics .2015 ;(473):458-468

27. 2015 Sheu MT,Jhan HJ,Hsieh CM,Wang CJ,Ho HO. Efficacy of antioxidants as a complementary and alternative medicine (CAM) in combination with the chemotherapeutic agent doxorubicin . Integrative Cancer Therapies .2015 ;(14):184-195

28. 2015 Hung SF,Hsieh CM,Chen YC,Lin CM,Ho HO,Sheu MT. Formulation and process optimization of multiparticulate pulsatile system delivered by osmotic pressure-activated rupturable membrane . International Journal of Pharmaceutics .2015 ;(480):15-26

29. 2015 Hung SF,Hsieh CM,Chen YC,Wang YC,Ho HO,Sheu MT. Characterizations of Plasticized Polymeric Film Coatings for Preparing Multiple-Unit Floating Drug Delivery Systems (muFDDSs) with Controlled-Release Characteristics . PLoS ONE .2015 ;(9):100321

30. 2014 Hsieh CM,Huang YW,Sheu MT,Ho HO. Biodistribution profiling of the chemical modified hyaluronic acid derivatives used for oral delivery system . International Journal of Biological Macromolecules .2014 ;(64):45-52

31. 2014 Chen YC,Ho HO,Chiu CC,Sheu MT. Development and characterization of a gastroretentive dosage form composed of chitosan and hydroxyethyl cellulose for alendronate . Drug Design, Development and Therapy .2014 ;(8):67-78

32. 2014 Kao YY,Cheng SC,Cheng CN,Shiea J,Ho HO. Detection of trace ink compounds in erased handwritings using electrospray-assisted laser desorption ionization mass spectrometry (Accepted for publication)DOI 10.1002/jms.3356 . Journal of Mass Spectrometry .2014 ;(0):0-0

33. 2014 Jhah HJ,Liu JJ,Chen YC,Liu DZ,Sheu MT,Ho HO. Novel Injectable Thermosensitive Hydrogels for Delivering Hyaluronic Acid-Doxorubicin Nanocomplexes to Locally Treat Tumors (Accepted for publication) . Nanomedicine – UK .2014 ;(0):0-0

34. 2013 Chen YC,Ho HO,Lee TY,Sheu MT. Physical characterizations and sustained release profiling of gastroretentive drug delivery systems with improved floating and swelling capabilities. . Int. J. Pharmaceutics .2013 ;(441):162-169

35. 2013 Lin SF,Chen YC,Ho HO,Huang WY,Sheu MT,Liu DZ. Development and characterization of dilutable self-microemulsifying premicroemulsion systems (SMEPMS) as templates for preparation of nanosized particulates . International Journal of Nanomedicine .2013 ;(8):3455-3466

36. 2013 Wu YN,Wu CC,Sheu MT,Chena KC,Ho HO,Chiang HS. Optimization of platelet-rich plasma and its effects on the recovery of erectile function after bilateral cavernous nerve injury in a rat model . Journal of Tissue Engineering and Regenerative Medicin .2013 ;(0):0-0

37. 2013 Yang Kuo, Li-Min,Zhang, Li-Jie,Huang, Hung-Tse,Lin, Zhi-Hu,Liao, Chia-Ching,Cheng, Hui-Ling; Lee, Kuo-Hsiung; Morris-Natschke, Susan; Kuo, Yao-Haur; Ho, Hsiu-O. Antioxidant Lignans and Chromone Glycosides from Eurya japonica (Accepteed for publication) . Journal of Natural Products .2013 ;(0):0-0

38. 2013 Kao YY,Cheng CN,Cheng SC,Ho HO,Shiea J. Distinguishing authentic and counterfeit banknotes by surface chemical composition determined using electrospray laser desorption ionization mass spectrometry (Accepted forpublication) . Journal of Mass Spectrometry .2013 ;(0):0-0

39. 2012 Wu JU,Ho HO,Chen YC,Chen CC,Sheu MT,陳盈真. Thermal analysis and dissolution characteristics of nifedipine solid dispersions . Journal of Food and Drug Analysis .2012 ;(20):27-33

40. 2012 Wu JU,Sheu MT,Lin JW,Liou YB,Chiu WT,Ho HO. Characterization of Glycerophospholipids and a Sphingolipid in the Cerebrospinal Fluid of Patients with Different Illnesses by LC-ESI-MS . Journal of Food and Drug Analysis .2012 ;(20):12-20

41. 2012 Chen YC,Liu DZ,Liu JJ,Chang TW,Ho HO,Sheu MT. Development of Terbinafine Solid Lipid Nanoparticles as a Topical Delivery System(Accepted for publication) . International Journal of Nanomedicine .2012 ;(0):1-10

42. 2012 Wu CC,Wu YN,Ho HO,Sheu MT,Chiang HS. The neuroprotective effect of platelet-rich plasma on erectile function in bilateral cavernous nerve injury rat model . Journal of Sexual Medicine .2012 ;(9):2838-2848

43. 2012 Chang SC,Lu ML,Wang YC,Lin FW,Huang SH,Kuo PH, Ho HO, Wu TH. Combined Therapy With Thioridazine Decreases Plasma Levels of Quetiapine in Taiwanese Schizophrenic Patients (Accepted for Publication) . Ther. Drug Monit. .2012 ;(0):0-0

44. 2011 Lu HT,Chen RN,Sheu MT,Chang CC,Chou PY,Ho HO. Rapid-onset sildenafil nasal spray carried by microemulsion systems: in vitro evaluation and in vivo pharmacokinetic studies in rabbits (Accepted for publication) . Xenobiotica .2011 ;(x):x-x

45. 2011 Sheu MT,Lin YK,Huang CH,Ho HO. Established HPLC Fraction Analysis to Predict Furanocoumarin-Based Herb-drug Metabolic Interactions . Phytotherapy Research .2011

46. 2011 Lin YM,Wu JY,Chen YC,Su YD,KeWT,Ho HO, Sheu MT. In-situ formation of nanocrystals from a self-microemulsifying drug delivery system (SMEDDS) to enhance oral bioavailability of fenofibrate (FFB) . International Journal of Nanomedicine .2011 ;(6):2445-2457

47. 2011 Chang CW,Ho HO,Lo YJ,Lee SY,Yang YR,Sheu MT. Development of swellable local implants of a polyethyleneimine-polyvinyl pyrrolidone (PEI-PVP) hydrogel as socket filler . Journal of Biomaterials Science:Polymer Edition .2011

48. 2010 Kuo YJ,Yang YC,Zhang LJ,Wu MD,Kuo Yang LM,Ho HO, Kuo YH. Flavanone and Diphenylpropane Glycosides and Glycosidic Acyl Esters from Viscum articulatum . J. Nat. Prod. .2010 ;(73):109-114

49. 2010 Liou YB,Sheu MT,Liu DZ,LinSY,Ho HO. Quantitation of ceramides in nude mouse skin by normal-phase liquid chromatography and atmospheric pressure chemical ionization mass spectrometry . Anal. Biochem. .2010 ;(401):107-113

50. 2010 Sheu MT,Liou YB,Kao YH,Lin YK,Ho HO. A Quantitative Structure Activity Relationship (QSAR) for the Modulation Effects of Flavonoids on P-Glycoprotein-Mediated Transport . Chem. Pharm. Bull. .2010 ;(58):1187-1194

51. 2010 Liu HC,Liu RH,Lin DL,Ho HO. Rapid screening and confirmation of drugs and toxic compounds in biological specimens using liquid chromatography/ion trap tandem mass spectrometry and automated library search . Rapid Commun. Mass Spectrom. .2010 ;(24):75-84

52. 2009 Liou YB*,Ho HO*,Yang CJ,Lin YK,Sheu MT. Construction of a Quantitative Structure Permeability Relationship (QSPR) for the Transdermal Delivery of NSAIDs. . Journal of Controlled Release .2009 ;(138):260-267

53. 2009 Kuo YJ,Hsiao PC,Zhang LJ,Wu MD,Liang YH,Ho HO*, Kuo YH*. Labdane Diterpenoid Glycosides from Alpinia densespicata and their Nitric Oxide Inhibitory Activities in Macrophages . J. Nat. Prod. .2009 ;(72):1097-1101

54. 2009 Liou YB,Ho HO,Chen SY,Sheu MT. Correlation of the penetration enhancement with the influence of an alcohol/tocopheryl polyethylene glycol succinate (TPGS) cosolvent system on the molecular structure of the stratum corneum of nude mouse skin as examined by microscopic FTIR/DSC(Accepted) . Spectrochimica ACTA Part A: Molecular and Biomolecular Spectroscopy. .2009 ;(74):695-703

55. 2009 Liu HC,Liu RH,Ho HO,Lin DL. Development of an Information-Rich LC-MS/MS Database for the Analysis of Drugs in Postmortem Specimens(Accepted for publication) . Anal. Chem. .2009 ;(81):9002-9011

56. 2009 Lin YK,Sheu MT,Huang CH,Ho HO. Dwevelopment of a reversed-phase high performance liquid chromatographic method for analyzing furanocoumarin components in Citrus fruit juices and Chinese herbal medicines(Accepted for publication) . Journal of Chromatograhic Sciences .2009 ;(47):211-215

57. 2008 Kuo YJ,Hwang SY,Wu MD,Liao CC,Liang YH,Kuo YH, Ho HO. Cytotoxic Constituents from Podocarpus fasciculus (Accepted for publication) . Chem. Pharm. Bull. .2008

58. 2008 Lin HL,Ho HO,Chen CC,Yeh TS,Sheu MT. Process and formulation characterizations of the thermal adhesion granulation (TAG) process for improving granular properties (Accepted for publication) . International Journal of Pharmaceutics .2008 ;(357):206-212

59. 2008 Lin Yk,Sheu MT,Tzen TZ,Ho HO. Biotransformation of sildenafil in the male rat: Evaluation of drug interactions with testosterone and carbamazepine (Accepted for Publication) . Drug Development and Industrial Pharmacy .2008 ;(34):1219-1225

60. 2008 Lou HY,Chang CC,Sheu MT,Chen YC,Ho HO. Optimal Dose Regimens of Esomeprazole for Gastric Acid Suppression with Minimal Influence of the CYP2C19 Polymorphism . Eur. J. Clin. Pharmacol. .2008 ;(00):00-00

61. 2007 Liu DZ,Sheu MT,Chen CH,Yang YR,Ho HO. Release Characteristics of Lidocaine from Local Implant of Polyanionic and Polycationic Hydrogels . Journal of Controlled Release .2007 ;(118):333-339

62. 2007 Lu HT,Liang YC,Sheu MT,Ho HO,Lin YT,Hsieh MS, Chen CH. Disease-modifying effects of glucosamine HCl involving regulation of metalloproteinases and chemokinesactivated by interleukin-1B in human primary synovial fibroblasts . Journal of Cellular Biochemistry .2007 ;(9999):1-13

63. 2006 Sheu MT,Wu AB,Lin KP,Shen CH,Ho HO. Effect of tocopheryl polyethylene glycol succinate (TPGS) on the percutaneous penetration of minoxidil from water/ethanol/polyethylene glycol (PEG) 400 solutions . Drug Development and Industrial Pharmacy .2006 ;(32):595-608

64. 2006 Liu HC,Ho HO,Liu RH,Yeh GC,Lin DL. Urinary excretion of morphine and codeine following the administration of single and multiple doses of opium preparations prescribed in Taiwan as “Brown Mixture”, . Journal of Anslytical Toxicology .2006 ;(30):225-231

65. 2005 Chen RN,Ho HO,Sheu MT. Characterization of collagen matrices crosslinked using microbial transglutaminase . Biomaterials .2005 ;(26):4229-4235

66. 2005 Wang CY,Ho HO,Ling LH,Lin YK,Sheu MT. Asymmetric membrane capsules for delivery of poorly water soluble drugs by osmotic effects (Accepted for publication) . International Journal of Pharmaceutics .2005 ;(297):89-97

67. 2005 Ke WT,Lin SY,Ho HO,Sheu MT. Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as a surfactant for the oral delivery of protein drugs . Journal of Controlled Release .2005 ;(102):489-507

68. 2005 Su CH,Liu SH,Yu SY,Hsieh YL,Ho HO,Hu CH, Sheu MT. Development of fungal mycelia as a skin substitute: Characterization of keratinocyte proliferation and matrix metalloproteinase expression during improvement in the wound-healing process . Journal of Biomedical Materials Research .2005 ;(72A):220-227

69. 2005 Lin PW,Chen CH,Ho HO,Chen YC,Sheu MT. Characterization of cortical neuron outgrowth in 2D and 3D culture systems (accepted for publication) . Journal of Biomedical Materials Research Part B .2005

70. 2005 Chen CH,Sheu MT,Wu AB,Lin KP,Ho HO. Simultaneous effects of tocopheryl polyethylene glycol succinate (TPGS) on local hair growth promotion and systemic absorption of topically applied minoxidil in a mouse model . International Journal of Pharmaceutics .2005 ;(306):91-98

71. 2005 Chen CH,Sheu MT,Lin KP,Ho HO. Simultaneous effects of tocopheryl polyethylene glycol succinate (TPGS) on local hair growth promotion and systemic absorption of topically applied minoxidil in a mouse model . International Journal of Pharmaceutics .2005 ;(306):91-98

72. 2004 Wu AB,Huang MC,Ho HO,Yeh GC,Sheu MT. Separation of Basic Compounds with a Simple Aqueous Mobile Phase . Biomedical Chromatography .2004

73. 2004 Chen RN,Ho HO,Tsai YT,Sheu MT. Process Development of an Acellular Dermal Matrix (ADM) for Biomedical Applications . Biomaterials .2004 ;(25):2679-2689

74. 2004 Wu AB,Huang MC,Ho HO,Yeh GC,Sheu MT. Investigation on liquid chromatographic separation of basic compounds using silica column with aqueous/organic mibile phase containing triethylamine and acetic acid . Biomedical Chromatography .2004 ;(18):443-449

75. 2004 Ho HO,Tsai YT,Chen RN,Sheu MT. Viscoelastic characterizations of acellular dermal matrix (ADM) preparations for use as injectable implants . Journal of Biomedical Material Research Part A .2004 ;(70A):97-106

76. 2003 Sheu MT, Chen SY, Chen LC, and Ho HO. Influence of Micelle Solubilization by Tocopheryl Polyethylene Glycol Succinate (TPGS) on Solubility Enhancement and Percutaneous Penetration of Estradiol . Journal of Controlled Release .2003 ;(88):355-368

77. 2003 Lin YK, and Ho HO. Investigations on the Drug Releasing Mechanism from an Asymmetric Membrane-Coated Capsule with an in-situ Formed Delivery Orifice, . Journal of Controlled Release .2003 ;(89):57-69

78. 2003 Sheu MT, Wu AB, Yeh GC, Hsia A, and Ho HO. Development of a Liquid Chromatographic Method for Bioanalytical Applications with Sildenafil, . Journal of Chromatography B .2003 ;(791):255-262

79. 2003 Sheu MT, Lin CW, Huang MC, Shen CH and Ho HO. Correlation of In vivo and In vitro Measurements of Sun Protection Factor . Journal of Food and Drug Analysis .2003 ;(2):128-132

80. 2003 Yeh GC,Tao PL,Ho HO,Lee YJ,Chen YR,Sheu MT. Analysis of Pharmacokinetic parameters for assessement of dextromethorphan metabolic phenotype . Journal of Biomedical Science .2003 ;(10):455-564

81. 2003 Sheu MT,Ho HO,Wang PY,Liou YB,Wu AB. Photolysis of NSAIDs. I. Photodegradation Products of Carprofen Determination by LC-ESI-MS . Journal of Chromatographic Science .2003 ;(41):200-204

82. 2002 Sheu MT, Chen LC, Ho HO. Simultaneous optimizaton of percutaneous delivery and adhesion for ketoprofen poultice . International Journal of Pharmaceutics .2002 ;(233):257-262

83. 2002 Sheu MT, Chen LC, Ho HO. Simultaneous optimization of percutaneous delivery and adhesion for ketoprofen poultice . International Journal of pharmaceutics .2002 ;(233):257-262

84. 2002 Sheu MT, Chen LC, Ho HO. Simultaneous optimization of percutaneous delivery and adhesion for ketoprofen poultice . International Journal of Pharmaceutics .2002 ;(233):257-262

85. 2002 Huang MC, Ho HO, Yeh GC, Ke WT, Lin LC, Hsu TM Bruce , Sheu MT. Application of HPLC method using normal phase column in a comparative pharmacokietic study of two sulpiride tablet formulations . Jpurnal of Food and Drug Analysis .2002 ;(10):1-6

86. 2002 Huang MC, Ho HO, Wen KC, Sheu MT. High Performance Liquid Chromatography Analysis of Tetrahydrozoline Hydrochloride in Ophthalmic Solution by Silica Column Eluted with Aqueous Solvent Mixtures . Journal of Food and Drug Analysis .2002 ;(10):88-94

87. 2002 Ho HO, Tsai T, Liu CM, Sheu MT. The influence of cosolvents and in situ-forming hydroxyapatite on the mechanical characteristics of collagen films . Journal of Biomedical Material Research .2002 ;(62):22-29

88. 2002 Hsieh MA, Ho HO, Wu J, Sheu MT. Mechanical performance of codried product of microcrystalline cellulose with b-cyclodextrin . New Taipei Journal of Medicine .2002 ;(4):117-125

89. 2002 Ho HO, Hsieh CM, Sheu MT. Characteristics of codried products of microcrystalline cellulose with saccharides and low-substituted hydroxypropylcellulose . Powder Technology .2002 ;(127):45-55

90. 2002 Ho HO, Su HL, Sheu MT. Polymer-granulated excipients as matrix material for the controlled delivery of nifedipine and its solid dispersion system . New Taipei Journa. of Medicine .2002 ;(4):175-184

91. 2002 Ho HO, Liu CM, Sheu MT. The influence of cosolvents and in situ-forming hydroxyapatite on permeation characteristics of collagen films . Chin. Pharm. J. .2002 ;(54):1-12

92. 2001 Huang MC, Ho HO, Yeh GC, Ke WT, Lin LC, Bruce TM, Kao CC, Sheu MT. Development of high performance liquid chromatographic method for bioanalytical application with sulpiride . Journal of Chromatography B: Biomedicial Sciences and Application .2001 ;(763):157-163

93. 2001 Ho HO, Lin CW, Sheu MT. Diffusion characteristics of collagen film . Journal of Controlled Release .2001 ;(77):97-105

94. 2001 Sheu MT, Hsia Angel and Ho HO. Polyglycolized saturated glyceride as a carrier and enhancer for drug penetration (Accepted for publication) . The Chinese Pharmaceutical Journal .2001 ;(51):215-219

95. 2001 Sheu MT, Wen TC, Ho HO, Chen KT, Chen SC and Chiang HS. Efficacy of transurethral delivery of prostagladin E1 carried by Gelucire in patients with erectile dysfunction . New Taipei Journal of Medicine .2001 ;(3):93-100

96. 2001 Wu JS, Ho HO and Sheu MT. A statistical design to evaluate the influence of manufacturing factors on the material properties and functionalities of microcrystalline cellulose (2000) Accepted . European Journal of Pharmaceutical Sciences .2001

97. 2001 Su CH, Yang YZ, Ho HO, Hu CH, Sheu MT. High Performance Liquid Chromatographic Analysis for the Characterization of Triterpenoids from Ganoderma. . Journal of Chromatographic Science .2001 ;(39):1-8

98. 2001 Ke WT, Ho HO, Tsai Tsuimin, Sheu MT.. Sustained-release effect of codried excipients of microcrystalline cellulose and Ganoderma Fiber (2001). . European Journal of Pharmaceutics and Biopharmaceutics. .2001

99. 2001 Ho HO, Huang JC, Sheu MT. Characterization of collagen gel solution and colagen matrix for cell culture, Accepted for Publication. . Biomaterials .2001 ;(22):1713-1719

100. 2000 Wu JS, Ho HO, Sheu MT. Influence of wet granulation and lubrication on the powder and tableting properties of codried product of microcrystalline cellulose with b-cbclodextrin . European Journal of Pharmaceutics and Biopharmaceutics .2000 ;(50):1-7

101. 2000 Sheu MT, Yeh GC, Ke WT, Ho HO. Development of a high-performance liquid chromatographic method for bioequivalence study of flavoxate tablets (accep) . Journal of Chromatography B .2000

102. 2000 Wu JS, Ho HO, Sheu MT. Direct Compression Acetaminophen: Preparation and Functional Modification by Co-Drying with Microcrystalline Cellulose . Chin Pharm. J. .2000 ;(52):151-165

103. 2000 Wu JS, Ho HO and Sheu MT. A statistical design to evaluate the influence of manufacturing factors and material properties on the mechanical performances of microcrystalline cellulose(accepted for publication) . Powder Technology .2000

104. 2000 Ho HO, Chen CN and Sheu MT. Influence of pluronic F-68 on dissolution and bioavailability characteristics of multiple layer pellets of nifedipine for controlled release delivery . Journal of Controlled Release .2000 ;(68):433-440

105. 2000 Chen JH, Ho HO, Yen KY, and Yang LL. Hepatoprotection by . The American Journal of Chinese Medicine .2000 ;(28):115-122

106. 1999 Su CH, Sun CS, Juan SW, Ho HO, Hu CH and Sheu MT. Development of Fungal Mycelia as Skin Substitutes: Effects on Wound Healing and Fibroblast . Biomaterial .1999 ;(20):61-68

107. 1999 Ho HO, Huang MC, Tseng SL, Lin LH, Chen KT, Chiang HS, Spur BW, Wong PYK and Sheu MT. The percutaneous penetration of prostaglandin E1 and its alkylester. . J. Controled Release .1999 ;(58):349-355

108. 1999 Su Ch, Sun CS, Juan SW, Ho HO, Chen KT, Hu C and Sheu MT. Development of fungal mycelia as skin substitutes II: effect on the wound healing process. . New Taipei Journal of Medicine .1999 ;(1):31-39

109. 1999 Yeh GC, Sheu MT, Yen CL, Wang YW, Liu CH and Ho HO. High-performance liquid chromatographic method for determination of tramadol in human plasma. . J. Chromatogr. B .1999 ;(723):247-253

110. 1998 Tsai T, Wu JS, Ho HO and Sheu MT. The Modification of physical characteristics of microcrystalline cellulose by codrying with cyclodextrin. . J. Pharm. Sci. .1998 ;(87):117-122

111. 1998 Ho HO, Chen LJ and Sheu MT. Penetration enhancement by menthol combined with a solubilization effect in a mixed solvent system. . J. Controlled Release .1998 ;(51):301-311

112. 1998 Tsai T, San YP, Ho HO and Sheu MT. Film-forming polymer granulated excipients as the matrix material for controlled release dosage forms. . J. Controlled Release .1998 ;(51):289-299

113. 1998 Lin LH, Ho HO, Chen KT, Chiang HS, Wong PYK and Sheu MT. The stability tests of prostaglandin E1 ethylester. . Chin. Pharm. J. .1998 ;(50):97-105

114. 1998 Ho HO, Huang MC, Chen LC, Hsia A, Chen KT, Chiang HS, Spur BW, Wong PYK and Sheu MT. The percutaneous delivery of prostaglandin E1 and its alkylester by microemulsions. . Chin. Pharm. J. .1998 ;(50):257-266

115. 1997 Ho HO, Lin LH and Sheu MT. Characterization of collagen isolation and application of collagen gel as a drug carrier. . J. Controlled Release .1997 ;(44):103-112

116. 1997 Tsai T, San YP, Ho HO, Kao CC and Sheu MT. Film-forming polymer granulated excipients as the matrix material for the production of pellets by extrusion/spheronization. . Chin. Pharm. J. .1997 ;(49):249-257

117. 1997 Ho HO, Liu CH, Lin HM and Sheu MT. The development of matrix tablets for diclofenac sodium on an empirical in vitro and in vivo correlation. . J. Controlled Release .1997 ;(49):149-156

118. 1997 Ho HO, Wang HY and Sheu MT. The evaluation of granulated excipients as matrix material for controlled delivery of captopril. . J. Controlled Release .1997 ;(49):243-251

119. 1996 Ho HO, Hsiao CC and Sheu MT. Preparation of microemulsions using polyglycerol fatty acid esters as surfactant for the delivery of protein drugs. . J. Pharm. Sci. .1996 ;(85):138-143

120. 1996 Ho HO, Su HL, Tsai T and Sheu MT. The preparation and characterization of solid dispersion on pellets sing a fluidized-bed system. . Int. J. Pharm. .1996 ;(139):223-229

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105 以局部控釋傳輸乘載doxorubicin及cisplatin之熱敏感性凝膠作為癌症結合治療應用之研究(2/3)
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104 以局部控釋傳輸乘載doxorubicin及cisplatin之熱敏感性凝膠作為癌症結合治療應用之研究(1/3)
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102 標靶性奈米脂雙層包體藥物制放系統技術平台及關鍵性生醫材料研發計畫(II)
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89 可供細胞生長的膠原蛋白間質之特性研究
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