| 1. |
2024
Tsou P,Wu CJ.
Classifying driver mutations of papillary thyroid carcinoma on whole slide image: an automated workflow applying deep convolutional neural network
. Frontiers in Endocrinology
.2024
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| 2. |
2024
Tsou P,Wu CJ.
Differential Characteristics on TCR Embedding Landscape Among Immune Checkpoint Blockade Responders Versus Non-Responders Against Non-Small Cell Lung Carcinoma
. Eur J Immunol.
.2024
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| 3. |
2024
Kumar D,Gurrapu S,Wang Y,Bae SY,Pandey PR,Chen H, Mondal J, Han H, Wu CJ, Karaiskos S, Yang F, Sahin A, Wistuba II, Gao J, Tripathy D, Gao H, Izar B, Giancotti FG.
LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells
. Nature Cancer
.2024
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| 4. |
2023
Li J,Lan Z,Liao W,Horner JW,Xu X,Liu J, Yoshihama Y, Jiang S, Shim HS, Slotnik M, LaBella KA, Wu CJ, Dunner K Jr, Hsu WH, Lee R, Khanduri I, Terranova C, Akdemir K, Chakravarti D, Shang X, Spring DJ, Wang YA, DePinho RA..
Histone demethylase KDM5D upregulation drives sex differences in colon cancer.
. Nature
.2023
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| 5. |
2023
Chung AK,Lin RT,Yeh CC,Yang CY,Wu CJ,Chen PL, Lin JT.
Diagnostic rate of germline pathogenic variants in pancreatic ductal adenocarcinoma patients using whole genome sequencing.
. Frontiers in Genetics
.2023
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| 6. |
2022
Andrews MC,Oba J,Wu CJ,Zhu H,Karpinets T,Creasy CA, Forget MA, Yu X, Song X, Mao X, Robertson AG, Romano G, Li P, Burton EM, Lu Y, Sloane RS, Wani KM, Rai K, Lazar AJ, Haydu LE, Bustos MA, Shen J, Chen Y, Morgan MB, Wargo JA, Kwong LN, Haymaker CL, Grimm EA, Hwu P, Hoon DSB, Zhang J, Gershenwald JE, Davies MA, Futreal PA, Bernatchez C, Woodman SE..
Multi-modal molecular programs regulate melanoma cell state
. Nature Communications
.2022
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| 7. |
2022
Chen Y,Yang S,Tavormina J,Tampe D,Zeisberg M,Wang H, Mahadevan KK, Wu CJ, Sugimoto H, Chang CC, Jenq RR, McAndrews KM, Kalluri R.
Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
. Cancer Cell
.2022
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| 8. |
2022
Gulhati P,Schalck A,Jiang S,Shang X,Wu CJ,Hou P, Ruiz SH, Soto LS, Parra E, Ying H, Han J, Dey P, Li J, Deng P, Sei E, Maeda DY, Zebala JA, Spring DJ, Kim M, Wang H, Maitra A, Moore D, Clise-Dwyer K, Wang YA, Navin NE, DePinho RA.
Targeting T cell checkpoints 41BB and LAG3 and myeloid cell CXCR1/CXCR2 results in antitumor immunity and durable response in pancreatic cancer
. Nature Cancer
.2022
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| 9. |
2022
Chen LC,Nersisyan S,Wu CJ,Chang CM,Tonevitsky A,Guo CL, Chang WC.
On the peptide binding affinity changes in population-specific HLA repertoires to the SARS-CoV-2 variants Delta and Omicron
. Journal of Autoimmunity
.2022
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| 10. |
2022
Lee R,Li J,Li J,Wu CJ,Jiang S,Hsu WH, Chakravarti D, Chen P, LaBella KA, Li J, Spring DJ, Zhao D, Wang YA, DePinho RA.
Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer.
. Cancer Discovery
.2022
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| 11. |
2021
Chen M,Chen R,Jin Y,Li J,Hu X,Zhang J, Fujimoto J, Hubert SM, Gay CM, Zhu B, Tian Y, McGranahan N, Lee WC, George J, Hu X, Chen Y, Wu M, Behrens C, Chow CW, Pham HHN, Fukuoka J, Wu J, Parra ER, Little LD, Gumbs C, Song X, Wu CJ, Diao L, Wang Q, Cardnell R, Zhang J, Wang J, Le X, Gibbons DL, Heymach JV, Jack Lee J, William WN Jr, Cheng C, Glisson B, Wistuba I, Andrew Futreal P, Thomas RK, Reuben A, Byers LA, Zhang J.
Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer
. Nature Communications
.2021
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| 12. |
2021
Yoshihama Y,LaBella KA,Kim E,Bertolet L,Colic M,Li J, Shang X, Wu CJ, Spring DJ, Wang YA, Hart T, DePinho RA.
AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase
. Proc Natl Acad Sci U S A.
.2021
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| 13. |
2021
Chakravarti D,Lee R,Multani AS,Santoni A,Keith Z,Hsu WH, Chang K, Reyes L, Rashid A, Wu CJ, Li J, Zhang J, Shim HS, Chandra K, Deng P, Spring DJ, Nielsen OH, Riis LB, Mayigegowda KK, Blutt SE, Zhang J, Younes M, DuPont A, Thirumurthi S, Vilar E, Estes MK, Colla S, Shroyer NF, DePinho RA.
Telomere dysfunction instigates inflammation in inflammatory bowel disease
. Proc Natl Acad Sci U S A.
.2021
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| 14. |
2021
Negrao MV,Skoulidis F,Montesion M,Schulze K,Bara I,Shen V, Xu H, Hu S, Sui D, Elamin YY, Le X, Goldberg ME, Murugesan K, Wu CJ, Zhang J, Barreto DS, Robichaux JP, Reuben A, Cascone T, Gay CM, Mitchell KG, Hong L, Rinsurongkawong W, Roth JA, Swisher SG, Lee J, Tsao A, Papadimitrakopoulou V, Gibbons DL, Glisson BS, Singal G, Miller VA, Alexander B, Frampton G, Albacker LA, Shames D, Zhang J, Heymach JV.
Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cance
. Journal for ImmunoTherapy of Cancer
.2021
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| 15. |
2021
Hou P,Ma X,Yang Z,Zhang Q,Wu CJ,Li J, Tan L, Yao W, Yan L, Zhou X, Kimmelman AC, Lorenzi PL, Zhang J, Jiang S, Spring D, Wang YA, DePinho RA.
USP21 deubiquitinase elevates macropinocytosis to enable oncogenic KRAS bypass in pancreatic cancer.
. Genes & Development
.2021
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| 16. |
2021
Chen Y,Kim J,Yang S,Wang H,Wu CJ,Sugimoto H, LeBleu VS, Kalluri R.
Type I collagen deletion in αSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer
. Cancer Cell
.2021
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| 17. |
2021
Shim HS,Horner JW,Wu CJ,Li J,Lan ZD,Jiang S, Xu X, Hsu WH, Zal T, Flores II, Deng P, Lin YT, Tsai LH, Wang YA, DePinho RA..
Telomerase Reverse Transcriptase Preserves Neuron Survival and Cognition in Alzheimer's Disease Models
. Nature Aging
.2021
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| 18. |
2021
Terranova CJ,Tang M,Maitituoheti M,Raman AT,Ghosh AK,Schulz J, Amin SB, Orouji E, Tomczak K, Sarkar S, Oba J, Creasy C, Wu CJ, Khan S, Lazcano R, Wani K, Singh A, Barrodia P, Zhao D, Chen K, Haydu LE, Wang WL, Lazar AJ, Woodman SE, Bernatchez C, Rai K.
Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy
. Cell Report
.2021
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| 19. |
2020
Subudhi SK,Vence L,Zhao H,Blando J,Yadav SS,Xiong Q, Reuben A, Aparicio A, Corn PG, Chapin BF, Pisters LL, Troncoso P, Tidwell RS, Thall P, Wu CJ, Zhang J, Logothetis CL, Futreal A, Allison JP, Sharma P.
Neoantigen responses, immune correlates, and favorable outcomes after ipilimumab treatment of patients with prostate cancer
. Science Translational Medicine
.2020
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| 20. |
2020
Lovisa S,Fletcher-Sananikone E,Sugimoto H,Hensel J,Lahiri S,Hertig A, Taduri G, Lawson E, Dewar R, Revuelta I, Kato N, Wu CJ, Bassett RL Jr, Putluri N, Zeisberg M, Zeisberg EM, LeBleu VS, Kalluri R.
Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis.
. Science Signaling
.2020
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| 21. |
2020
Lee WC,Reuben A,Hu X,McGranahan N,Chen R,Jalali A, Negrao MV, Hubert SM, Tang C, Wu CC, Lucas AS, Roh W, Suda K, Kim J, Tan AC, Peng DH, Lu W, Tang X, Chow CW, Fujimoto J, Behrens C, Kalhor N, Fukumura K, Coyle M, Thornton R, Gumbs C, Li J, Wu CJ, Little L, Roarty E, Song X, Lee JJ, Sulman EP, Rao G, Swisher S, Diao L, Wang J, Heymach JV, Huse JT, Scheet P, Wistuba II, Gibbons DL, Futreal PA, Zhang J, Gomez D, Zhang J..
Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity
. Genome Biology
.2020
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| 22. |
2020
Zhao D,Cai L,Lu X,Liang X,Li J,Chen P, Ittmann M, Shang X, Jiang S, Li H, Meng C, Flores I, Song JH, Horner JW, Lan Z, Wu CJ, Li J, Chang Q, Chen KC, Wang G, Deng P, Spring DJ, Wang YA, DePinho RA.
Chromatin Regulator CHD1 Remodels the Immunosuppressive Tumor Microenvironment in PTEN-Deficient Prostate Cancer
. Cancer Discovery
.2020
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| 23. |
2020
Hou P,Kapoor A,Zhang Q,Li J,Wu CJ,Li J, Lan Z, Tang M, Ma X, Ackroyd JJ, Kalluri R, Zhang J, Jiang S, Spring DJ, Wang YA, DePinho RA.
Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer
. Cancer Discovery
.2020
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