楊奕婕(Yang, Yi-Chieh) 助理教授

Email
ycyang@tmu.edu.tw
現   職
口腔衛生學系 助理教授

學經歷

學 歷

畢業學校與學位[修業時間]
國立臺灣大學醫學院腫瘤醫學研究所 博士
2011/09~2017/03
國立成功大學藥理學研究所 碩士
2009/09~2011/06
中國醫藥大學藥學系 學士
2004/09~2009/06

本校學術經歷

任職單位與職稱[起迄時間]
口腔衛生學系助理教授
2024/11/01~

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
童綜合醫院助研究員
2022/07/01~2024/10/31
童綜合醫院博士後研究員
2019/08/01~2022/06/30
臺北醫學大學博士後研究員
2017/03/14~2019/07/31

專長與研究領域

學門領域
學術專長
分子藥理
分子藥理
癌症藥理
癌症藥理
癌腫瘤學
癌腫瘤學
口腔癌
口腔癌
口腔腫瘤
口腔腫瘤

論文著作

清冊下載


1. 2024 Chien MH,Yang YC,Ho KH,Ding YF,Chen LH,Chiu WK, Chen JQ, Tung MC, Hsiao M, Lee WJ. Cyclic increase in the ADAMTS1-L1CAM-EGFR axis promotes the EMT and cervical lymph node metastasis of oral squamous cell carcinoma. . Cell Death and Disease .2024 ;(15)

2. 2024 Wen YC,Lin YW,Ho KH,Yang YC,Lai FR,Chu CY, Chen JQ, Lee WJ, Chien MH. The oncogenic ADAMTS1-VCAN-EGFR cyclic axis drives anoikis resistance and invasion in renal cell carcinoma. . Cell Mol Biol Lett .2024

3. 2024 Yang YC,Ho KH,Hua KT,Chien MH. Roles of K(H)SRP in modulating gene transcription throughout cancer progression: Insights from cellular studies to clinical perspectives. . Biochim Biophys Acta Rev Cancer .2024

4. 2024 Yang YC,Ho KH,Pan KF,Hua KT,Tung MC,Ku CC, Chen JQ, Hsiao M, Chen CL, Lee WJ, Chien MH. ESM1 facilitates the EGFR/HER3-triggered epithelial-to-mesenchymal transition and progression of gastric cancer via modulating interplay between Akt and angiopoietin-2 signaling. . International Journal of Biological Sciences .2024

5. 2023 Yang YC,Lin YW,Lee WJ,Lai FR,Ho KH,Chu CY, Hua KT, Chen JC, Tung MC, Hsiao M, Wen YC, Chien MH. The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase. . J Biomedical Science .2023 ;(30)

6. 2023 Lee Kai-Ling,Lai Tsung Ching,Lee Wei-Jiunn,Chen Yu-Chieh,Ho Kuo-Hao,Hung Wen-Yueh,Yang Yi-Chieh,Chan Ming-Hsien,Hsieh Feng-Koo,Chung Chi-Li,Chang Jer-Hwa,Chien Ming-Hsien,Lee Kai-Ling,Lai Tsung Ching,Lee Wei-Jiunn,Chen Yu-Chieh,Ho Kuo-Hao,Hung Wen-Yueh,Yang Yi-Chieh,Chan Ming-Hsien,Hsieh Feng-Koo,Chung Chi-Li,Chang Jer-Hwa,Chien Ming-Hsien. Sustaining the Activation of EGFR Signal by Inflammatory Cytokine IL17A Prompts Cell Proliferation and EGFR-TKI Resistance in Lung Cancer . Cancers .2023 ;(15)

7. 2023 Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition . Cells .2023 ;(12)

8. 2022 Genetic Polymorphisms of lncRNA LINC00673 as Predictors of Hepatocellular Carcinoma Progression in an Elderly Population . International journal of molecular sciences .2022 ;(23):12737-12737

9. 2022 Yang YC,Pan KF,Lee WJ,Hua KT,Chien MH. Proteoglycan Endocan: A multifaceted therapeutic target in Cancer. . Biochim Biophys Acta Rev Cancer .2022 ;(1877)

10. 2022 Tung MC,Lin YW,Lee WJ,Wen YC,Liu YC,Chen JQ, Hsiao M, Yang YC, Chien MH. Targeting DRD2 by the antipsychotic drug, penfluridol, retards growth of renal cell carcinoma via inducing stemness inhibition and autophagy-mediated apoptosis. . Cell Death and Disease .2022 ;(13)

11. 2022 Ding YF,Lin YW,Chiu WK,Lin CW,Yang YC,Chang LC, et al. Combined impacts of histamine receptor H1 gene polymorphisms and an environmental carcinogen on the susceptibility to and progression of oral squamous cell carcinoma . Aging .2022 ;(14):4500-4512

12. 2021 Hung WY,Lee WJ,Cheng GZ,Tsai CH,Yang YC,Lai TC, et al. Blocking MMP-12-modulated epithelial-mesenchymal transition by repurposing penfluridol restrains lung adenocarcinoma metastasis via uPA/uPAR/TGF-β/Akt pathway . Cellular Oncology .2021 ;(44):1087-1103

13. 2021 Combined Impacts of Genetic Variants of Long Non-Coding RNA MALAT1 and the Environmental Carcinogen on the Susceptibility to and Progression of Oral Squamous Cell Carcinoma. . Front Oncol .2021

14. 2021 Histone methyltransferase g9a-promoted progression of hepatocellular carcinoma is targeted by liver-specific hsa-mir-122 . Cancers .2021 ;(13)

15. 2021 Lee Kai Ling,Lai Tsung Ching,Wang Yao Chen,Shih Pei Chun,Yang Yi Chieh,Tsao Thomas Chang Yao,Liu Tu Chen,Wen Yu Ching,Chang Lun Ching,Yang Shun Fa,Chien Ming Hsien,Lee Kai Ling,Lai Tsung Ching,Wang Yao Chen,Shih Pei Chun,Yang Yi Chieh,Tsao Thomas Chang Yao,Liu Tu Chen,Wen Yu Ching,Chang Lun Ching,Yang Shun Fa,Chien Ming Hsien. Potential impacts of interleukin-17a promoter polymorphisms on the egfr mutation status and progression of non-small cell lung cancer in Taiwan . Genes .2021 ;(12)

16. 2021 Pan Ke Fan,Lee Wei Jiunn,Chou Chun Chi,Yang Yi Chieh,Chang Yu Chan,Chien Ming Hsien,Hsiao Michael, Hua Kuo Tai,Pan Ke Fan,Lee Wei Jiunn,Chou Chun Chi,Yang Yi Chieh,Chang Yu Chan,Chien Ming Hsien,Hsiao Michael,Hua Kuo Tai. Direct interaction of β-catenin with nuclear ESM1 supports stemness of metastatic prostate cancer . EMBO Journal .2021 ;(40):e105450-e105450

17. 2021 Yang YC,Chien MH,Lai TC,Tung MC,Jan YH,Chang WM, Jung SM, Chen MH, Yeh CN, Hsiao M. Proteomics-based identification of TMED9 is linked to vascular invasion and poor prognoses in patients with hepatocellular carcinoma. . J Biomedical Science .2021

18. 2020 Yang YC,Chien MH,Lai TC,Su CY,Jan YH,Hsiao M, Chen CL. Monoamine Oxidase B Expression Correlates with a Poor Prognosis in Colorectal Cancer Patients and Is Significantly Associated with Epithelial-to-Mesenchymal Transition-Related Gene Signatures. . Int J Mol Sci .2020

19. 2020 Chang Jer Hwa,Lai Tsung Ching,Yang Po Jen,Shih Pei Chun,Yang Yi Chieh,Lee Kai Ling,Liu Tu Chen,Chang-Yao Tsao Thomas,Yang Shun Fa,Chien Ming Hsien,Chang Jer Hwa,Lai Tsung Ching,Yang Po Jen,Shih Pei Chun,Yang Yi Chieh,Lee Kai Ling,Liu Tu Chen,Chang-Yao Tsao Thomas,Yang Shun Fa,Chien Ming Hsien. Associations of timp-3 genetic polymorphisms with egfr statuses and cancer clinicopathologic development in lung adenocarcinoma patients . International journal of molecular sciences .2020 ;(21):1-13

20. 2020 Wen YC,Lin YW,Chu CY,Yang YC,Yang SF,Liu Yu Fan,Hsiao Michael,Lee Wei Jiunn,Chien Ming Hsien,Wen Yu Ching,Lin Yung Wei,Chu Chih Ying,Yang Yi Chieh,Yang Shun Fa,Liu Yu Fan,Hsiao Michael,Lee Wei Jiunn,Chien Ming Hsien. Melatonin-triggered post-transcriptional and post-translational modifications of ADAMTS1 coordinately retard tumorigenesis and metastasis of renal cell carcinoma . Journal of Pineal Research .2020 ;(69)

21. 2020 Lin Yung Wei,Wen Yu Ching,Chu Chih Ying,Tung Min Che,Yang Yi Chieh,Hua Kuo Tai,Pan Ke Fan,Hsiao Michael,Lee Wei Jiunn,Chien Ming Hsien,Lin Yung Wei,Wen Yu Ching,Chu Chih Ying,Tung Min Che,Yang Yi Chieh,Hua Kuo Tai,Pan Ke Fan,Hsiao Michael,Lee Wei Jiunn,Chien Ming Hsien. Stabilization of ADAM9 by N-α-acetyltransferase 10 protein contributes to promoting progression of androgen-independent prostate cancer . Cell Death and Disease .2020 ;(11)

22. 2020 Chien Ming Hsien,Yang Wei En,Yang Yi Chieh,Ku Chia Chi,Lee Wei Jiunn,Tsai Meng Ying,Lin Chiao Wen,Yang Shun Fa,Chien Ming Hsien,Yang Wei En,Yang Yi Chieh,Ku Chia Chi,Lee Wei Jiunn,Tsai Meng Ying,Lin Chiao Wen,Yang Shun Fa. Dual targeting of the p38 MAPK‐HO‐1 axis and cIAP1/XIAP by demethoxycurcumin triggers caspase‐mediated apoptotic cell death in oral squamous cell carcinoma cells . Cancers .2020 ;(12)

23. 2020 Chan YC,Chang YC,Chuang HH,Yang YC,Lin YF,Huang Ming Shyan,Hsiao Michael,Yang Chih Jen,Hua Kuo Tai,Chan Yung Chieh,Chang Yu Chan,Chuang Hsiang Hao,Yang Yi Chieh,Lin Yuan Feng,Huang Ming Shyan,Hsiao Michael,Yang Chih Jen,Hua Kuo Tai. Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFNγ axis . Oncogene .2020 ;(39):2509-2522

24. 2020 Yang YC,Pan KF,Lee WJ,Chang JH,Tan P,Gu CC, Chang WM, Yang SF, Hsiao M, Hua KT, Chien MH. Circulating Proteoglycan Endocan Mediates EGFR-Driven Progression of Non–Small Cell Lung Cancer . Cancer Research .2020 ;(80):3292-3304

研究計畫

計畫名稱
113 新聘教師研究補助
補助單位
臺北醫學大學