張哲邁(CHANG CHE-MAI) 助理教授

Email
cmchang@tmu.edu.tw
現   職
臨床基因體學暨蛋白質體學碩士學位學程 助理教授

學經歷

學 歷

畢業學校與學位[修業時間]
臺北醫學大學醫學生物科技博士學位學程 博士
2016/09~2022/01
英國伯明罕大學分子生物科技學系 碩士
2011/09~2012/09
高雄醫學大學生物科技學系 學士
2005/09~2009/06

本校學術經歷

任職單位與職稱[起迄時間]
臨床基因體學暨蛋白質體學碩士學位學程助理教授
2024/08/01~

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
臨床藥學學科助理教授
2024/11/01 ~

其它經歷

任職單位與職稱[起迄時間]
國家衛生研究院博士後研究員
2024/02/07~2024/06/30
中央研究院博士後研究員
2023/01/11~2024/01/31
雙和醫院博士後研究員
2022/04/06~2022/12/31
高雄醫學大學研究助理
2016/02/01~2016/08/31
臺北醫學大學研究助理
2012/10/16~2016/01/31
高雄醫學大學研究助理
2010/09/01~2011/06/30

專長與研究領域

學門領域
藥學及中醫藥學
Pharmacy and Chinese Medicine
學術專長
藥物基因體學
藥物基因體學
免疫學
免疫學
基因體學
基因體學

論文著作

清冊下載


1. 2024 Chang CM,Chang WC,Hsieh SL. Characterization of the genetic variation and evolutionary divergence of the CLEC18 family . J Biomed Sci .2024 ;(31):53-53

2. 2024 Ho SY,Kao CC,Chang CM,Chou YC,Luo WT,Chou WH, Tsai IL, Wu MS, Chang WC. Characterization of T-Cell receptor repertoire in immunoglobulin a nephropathy . Biomark Res .2024 ;(12):23-23

3. 2024 Liu WC,Chang CM,Zhang Y,Liao HT,Chang WC. Dynamics of T-cell receptor repertoire in patients with ankylosing spondylitis after biologic therapy . Int Immunopharmacol .2024 ;(127):111342-111342

4. 2023 Nguyen QA,Chou WH,Hsieh MC,Chang CM,Luo WT,Tai YT, Chang WC. Genetic alterations in peritoneal metastatic tumors predicted the outcomes for hyperthermic intraperitoneal chemotherapy . Front Oncol .2023 ;(13):1054406-1054406

5. 2023 Ho SY,Chang CM,Liao HN,Chou WH,Guo CL,Yen Y, Nakamura Y, Chang WC. Current Trends in Neoantigen-Based Cancer Vaccines . Pharmaceuticals .2023 ;(16):392-392

6. 2022 Chen LC,Nersisyan S,Wu CJ,Chang CM,Tonevitsky A,Guo CL, Chang WC. On the peptide binding affinity changes in population-specific HLA repertoires to the SARS-CoV-2 variants Delta and Omicron . J Autoimmun .2022 ;(133):102952-102952

7. 2022 Chang CM,Peng KY,Chan CK,Lin YF,Liao HW,Chang JG, Wu MS, Wu VC, Chang WC. Divergent Characteristics of T-Cell Receptor Repertoire Between Essential Hypertension and Aldosterone-Producing Adenoma . Front Immunol .2022 ;(13):853403-853403

8. 2022 Lin MR,Chang CM,Ting J,Chang JG,Chou WH,Huang KJ, Cheng G, Chang HH, Chang WC. Application of Whole Exome Sequencing and Functional Annotations to Identify Genetic Variants Associated with Marfan Syndrome . J Pers Med .2022 ;(12):198-198

9. 2021 Chang CM,Feng PH,Wu TH,Alachkar H,Lee KY,Chang WC. Profiling of T Cell Repertoire in SARS-CoV-2-Infected COVID-19 Patients Between Mild Disease and Pneumonia . J Clin Immunol .2021 ;(41):1131-1145

10. 2020 Chang CM,Liao YM,Lan GY,Chang WC,Yen Y. Using T-cell repertoire profiles as predictor in a primary mucosal melanoma . Clin Transl Med .2020 ;(10):e136-e136

11. 2019 Chang CM,Hsu YW,Wong HS,Wei JC,Liu X,Liao HT, Chang WC. Characterization of T-Cell Receptor Repertoire in Patients with Rheumatoid Arthritis Receiving Biologic Therapies . Dis Markers .2019

12. 2019 Wong JH,Wang YS,Nam S,Ho KH,Chang CM,Chen KC, Chen YF, Chang WC. Phthalate plasticizer di(2-ethyl-hexyl) phthalate induces cyclooxygenase-2 expression in gastric adenocarcinoma cells . Environ Toxicol .2019

13. 2019 Chang CM,Wong HS,Huang CY,Hsu WL,Maio ZF,Chiu SJ, Tsai YT, Chen BK, Wan YY, Wang JY, Chang WC. Functional Effects of let-7g Expression in Colon Cancer Metastasis . Cancers (Basel) .2019

14. 2017 Wong JH,Ho KH,Nam S,Hsu WL,Lin CH,Chang CM, Wang JY, Chang WC. Store-operated Ca2+ Entry Facilitates the Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Gastric Cancer Cells . Sci Rep .2017

15. 2017 Wong HS,Chang CM,Kao CC,Hsu YW,Liu X,Chang WC, Wu MS, Chang WC. V-J combinations of T-cell receptor predict responses to erythropoietin in end-stage renal disease patients . J Biomed Sci .2017

16. 2016 Wong HS,Chang CM,Liu X,Huang WC,Chang WC. Characterization of cytokinome landscape for clinical responses in human cancers . Oncoimmunology .2016

17. 2016 Klahan S,Huang WC,Chang CM,Wong HS,Huang CC,Wu MS, Lin YC, Lu HF, Hou MF, Chang WC. Gene expression profiling combined with functional analysis identify integrin beta1 (ITGB1) as a potential prognosis biomarker in triple negative breast cancer . Pharmacol Res .2016

18. 2015 Yang IH,Wong JH,Chang CM,Chen BK,Tsai YT,Chen WC, Wang ET, Hsu WL, Chang WC. Involvement of intracellular calcium mobilization in IL-8 activation in human retinal pigment epithelial cells . Invest Ophthalmol Vis Sci .2015

19. 2015 Tsai YT,Chang CM,Wang JY,Hou MF,Wang JM,Shiurba R, Chang WC, Chang WC. Function of DNA methyltransferase 3a in lead (Pb(2+) )-Induced Cyclooxygenase-2 gene . Environ Toxicol .2015

20. 2015 Lin YC,Wei PL,Tsai YT,Wong JH,Chang CM,Wang JY, Hou MF, Lee YC, Chuang HY, Chang WC. Pb²⁺ induced IL-8 gene expression by extracellular signal-regulated kinases and the transcription factor, activator protein 1, in human gastric carcinoma cells . Environ Toxicol .2015

21. 2014 Wang YJ,Hsu YW,Chang CM,Wu CC,Ou JC,Tsai YR, Chiu WT, Chang WC, Chiang YH, Chen KY. The influence of BMX gene polymorphisms on clinical symptoms after mild traumatic brain injury . Biomed Res Int .2014

22. 2014 Yen JH,Chang CM,Hsu YW,Lee CH,Wu MS,Hwang DY, Chen BK, Liao HT, Wu MT, Chang WC. A polymorphism of ORAI1 rs7135617, is associated with susceptibility to rheumatoid arthritis . Mediators Inflamm .2014

23. 2013 Hsu WL,Chiu SJ,Tsai YT,Chang CM,Wang JY,Wang ET, Hou MF, Huang CY, Sheu JH, Chang WC. A soft coral natural product, 11-episinulariolide acetate, inhibits gene expression of cyclooxygenase-2 and interleukin-8 through attenuation of calcium signaling . Molecules .2013

24. 2013 Guo YC,Chang CM,Hsu WL,Chiu SJ,Tsai YT,Chou YH, Hou MF, Wang JY, Lee MH, Tsai KL, Chang WC. Indomethacin inhibits cancer cell migration via attenuation of cellular calcium mobilization . Molecules .2013

研究計畫

計畫名稱
113 新聘教師研究補助
補助單位
臺北醫學大學

計畫名稱
113 透過高通量定序分析台灣族群之免疫藥物基因組短期和長期動態
補助單位
國家科學及技術委員會