李丞釩(Lee, Cheng-Fan) 助理教授

Email
bryancflee@tmu.edu.tw
現   職
生物化學暨細胞分子生物學科 助理教授

學經歷

學 歷

畢業學校與學位[修業時間]
國立臺灣大學醫學院生物化學暨分子生物研究所 博士
2012/09~2019/06
臺北醫學大學醫學檢驗暨生物技術學系 碩士
2008/09~2011/06
臺北醫學大學公共衛生學系 學士
2004/09~2008/06

本校學術經歷

任職單位與職稱[起迄時間]
生物化學暨細胞分子生物學科助理教授
2024/03/25~

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
美國約翰霍普金斯醫學院博士後研究員
2022/01~2024/02
國立台灣大學博士後研究員
2019/10~2021/12

專長與研究領域

學門領域
醫學生化及分子生物
Medical Biochemistry and Molecular Biology
學術專長
醫學之生化及分子生物
Biochemistry and Molecular Biology - Medicine
蛋白質體學
蛋白質體學
癌腫瘤學
癌腫瘤學
泌尿腫瘤學
泌尿腫瘤學
代謝質體學
代謝質體學

論文著作

清冊下載


1. 2025 Cheng-Fan Lee,Kenneth J. Pienta,Sarah R. Amend. The involvement of Cyclin-Dependent Kinase 7 (CDK7) and 9 (CDK9) in coordinating transcription and cell cycle checkpoint regulation . Cell Cycle .2025

2. 2024 Chung-Hsin Chen,Hsiang-Po Huang,Kai-Hsiung Chang,Ming-Shyue Lee,Cheng-Fan Lee,Chih-Yu Lin, Yuan Chi Lin, William J Huang, Chun-Hou Liao, Chih-Chin Yu, Shiu-Dong Chung, Yao-Chou Tsai, Chia-Chang Wu, Chen-Hsun Ho, Pei-Wen Hsiao, Yeong-Shiau Pu. Predicting clinically significant prostate cancer using urine metabolomics via liquid chromatography mass spectrometry . The World Journal of Men’s Health .2024

3. 2023 Chung-Hsin Chen,Hsiang-Po Huang,Kai-Hsiung Chang,Ming-Shyue Lee,Cheng-Fan Lee,Chih-Yu Lin, Yuan Chi Lin, William J Huang, Chun-Hou Liao, Chih-Chin Yu, Shiu-Dong Chung, Yao-Chou Tsai, Chia-Chang Wu, Chen-Hsun Ho, Pei-Wen Hsiao, Yeong-Shiau Pu. Prediction of clinically significant prostate cancer through urine metabolomic signatures: A large-scale validated study . Journal of Translational Medicine .2023

4. 2023 Nora M Haney,Chi-Ju Kim,Morgan D Kuczler,Cheng-Fan Lee,Kara Lombardo,Trinity J Bivalacqua, Kenneth J Pienta, Sarah R Amend. Novel urinary tract obstruction marker discovery by multi-marker profiling of urinary extracellular vesicles derived from a rat UTO model . Am J Clin Exp Urol .2023

5. 2022 Chi-Ju Kim,Anna LK Gonye,Kevin Truskowski,Cheng-Fan Lee,Kenneth J Pienta,Sarah R Amend. Nuclear morphology and functional characteristics that enable survival of cells in the polyaneuploid cancer cell state following cytotoxic chemotherapy . Neoplasia .2022

6. 2022 Wei-Zhen Lu,Hui-An Lin,Sen-Kuang Hou ,Cheng-Fan Lee,Chyi-Huey Bai,Sheng-Feng Lin.. Split-hand Index for Amyotrophic Lateral Sclerosis Diagnosis: A Frequentist and Bayesian Meta-analysis . Clinical Neurophysiology .2022

7. 2022 Hsin-Ying Lin,Chun-Jung Ko ,Tzu-Yu Lo,Shang-Ru Wu,Shao-Wei Lan,Chen-An Huang, Yi-Chin Lin, Hsin-Hsien Lin, Hsin-Fang Tu, Cheng-Fan Lee, Pei-Wen Hsiao, Hsiang-Po Huang, Mei-Jou Chen, Kai-Hsiung Chang, Ming-Shyue Lee.. Matriptase-2/NR4A3 axis switches TGF-β action toward suppression of prostate cancer cell invasion, tumor growth, and metastasis . Oncogene .2022

8. 2022 Cheng‐Fan Lee,Yu‐An Chen,Elizabeth Hernandez,Rey‐Chen Pong,Shihong Ma,Mia Hofstad, Payal Kapur, Haiyen Zhau, Leland WK Chung, Chih‐Ho Lai, Ho Lin, Ming‐Shyue Lee, Ganesh V Raj, Jer‐Tsong Hsieh. The central role of Sphingosine kinase 1 in the development of neuroendocrine prostate cancer (NEPC): A new targeted therapy of NEPC. . Clin Transl Med .2022

9. 2021 Hsin-Fang Tu,Chun-Jung Ko,,Ching-Tai Lee,Cheng-Fan Lee,Shao-Wei Lan,Hsin-Hsien Lin, Hsin-Ying Lin, Chia-Chi Ku, Der-Yen Lee, I-Chun Chen, Ya-Hui Chuang, Francisco Del Caño-Ochoa, Santiago Ramón-Maiques, Chao-Chi Ho, Ming-Shyue Lee, Geen-Dong Chang. Afatinib exerts immunomodulatory effects by targeting the pyrimidine biosynthesis enzyme CAD . Cancer Research .2021

10. 2021 Ji‐Ming Bao,Qiang Dang,Chun‐Jung Lin,U‐Ging Lo,Boris Feldkoren,Andrew Dang, Elizabeth Hernandez, Fei Li, Vandana Panwar, Cheng‐Fan Lee, Jun‐Jie Cen, Bing Guan, Vitaly Margulis, Payal Kapur, Rolf A Brekken, Jun‐Hang Luo, Jer‐Tsong Hsieh, Wan‐Long Tan. SPARC is a key mediator of TGF‐β‐induced renal cancer metastasis . Journal of cellular physiology .2021

11. 2020 Ashley M Lakoduk,Cheng-Fan Lee,Ping-Hung Chen. Gain-of- “endocytic’function in mutant p53 cancer cells . JBC .2020

12. 2020 Chun-Jung Ko,Ting-Wei Hsu,Shang-Ru Wu,Shao-Wei Lan,Ting-Feng Hsiao,Hsin-Ying Lin, Hsin-Hsien Lin, Hsin-Fang Tu, Cheng-Fan Lee, Cheng-Chung Huang, Mei-Ju May Chen, Pei-Wen Hsiao, Hsiang-Po Huang, Ming-Shyue Lee,. Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis . Oncogene .2020

13. 2019 Lee CF,Dang A,Hernandez E,Pong RC,Chen B,Sonavane R, Raj G, Kapur P, Lin HY, Wu SR, Ko CJ, Lo UG, Lee HY, Hsieh JT, Lee MS. Activation of sphingosine kinase by lipopolysaccharide promotes prostate cancer cell invasion and metastasis via SphK1/S1PR4/matriptase . Oncogene .2019

14. 2017 U-Ging Lo,Cheng-Fan Lee,Ming-Shyue Lee,Jer-Tsong Hsieh. The Role and Mechanism of Epithelial-to-Mesenchymal Transition in Prostate Cancer Progression . IJMS .2017

15. 2015 Chen CY,Lin YS,Chen CL,Chao PZ,Chiou JF,Kuo CC, Lee FP, Lin YF, Sung YH, Lin YT, Lee CF, Chen YJ, Chen CH. Targeting annexin A2 reduces tumorigensis and therapeutic resistance of nasopharyngeal carcinoma . Oncotarget .2015

16. 2015 Huang PT,Chen CH,Hsu IU,Salim SA,Kao SH,Cheng CW, Lai CH, Lee CF, Lin YF. Huntingtin-Associated Protein 1 Interacts with Breakpoint Cluster Region Protein to Regulate Differentiation . Plos one .2015

研究計畫

計畫名稱
113 探討轉錄重塑機制與脂質代謝變化對攝護腺癌抗藥性演化研究(1/2)
補助單位
國家科學及技術委員會

計畫名稱
112 新聘教師研究補助
補助單位
臺北醫學大學