李佳蓉(Lee, Chia-Jung ) 教授

Email
cjlee@tmu.edu.tw
現   職
中草藥臨床藥物研發博士學位學程 教授

學經歷

學 歷

畢業學校與學位[修業時間]
台北醫學大學藥學系博士班 博士
2006/09~2011/06
台北醫學大學生藥學研究所 碩士
2003/09~2005/06
台北醫學大學藥學系 學士
1999/09~2003/06

本校學術經歷

任職單位與職稱[起迄時間]
中草藥臨床藥物研發博士學位學程教授
2024/08/01~
中草藥臨床藥物研發博士學位學程副教授
2021/02/01~2024/07/31
中草藥臨床藥物研發博士學位學程助理教授
2015/03/17~2021/01/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
服務學習中心主任
2021/08/01 ~ 2023/08/31
生藥學研究所助理教授
2019/05/01 ~

其它經歷

任職單位與職稱[起迄時間]
千葉大學醫學部訪問學者
2014/04~2015/03
陽明大學專案助理教授
2013/07~2014/02
陽明大學博士後研究
2011/10~2013/06

專長與研究領域

學門領域
中醫藥
藥理及毒理
藥學
學術專長

論文著作

清冊下載


1. 2023 Hsieh CY,Wang CC,Lemmuel L. Tayo,Tsai PW,Lee CJ. Identification for metabolism profiles and pharmacokinetic studies of tradition Chinese prescription Ji-Ming-San and its major metabolites in rats by UHPLC-Q-TOF-MS/MS and UHPLC-MS/MS . Journal of Food and Drug Analysis .2023

2. 2023 Wang KT,Lee CJ,Lee MC,Chen CY,Tsai YC,Chuang WC. An integrative approach for compressive quality control of RespireAidTM, a traditional Chinese medicine formula against SARS-CoV-2 . Journal of Food and Drug Analysis .2023

3. 2023 Huang SM#,Hsieh CY#,Jasmine U. Ting,Kathlia A. De Castro-Cruz,Wang CC,Lee CJ*, Tsai PW*. Anti-COVID-19, Anti-Inflammatory, and Anti-Osteoarthritis Activities of Sesamin from Sesamum indicum L. . Bioengineering .2023 ;(10)

4. 2023 Hsieh CY,Tsai PW,Yoshihisa Tomioka,Yotaro Matsumoto,Yasutoshi Akiyama,Wang CC, Lee MC, Lemmuel L. Tayo, Lee CJ. Chronopharmacology of diuresis via metabolic profiling and key biomarker discovery of the Traditional Chinese Prescription Ji-Ming-San using tandem mass spectrometry in rat models . Phytomedicine .2023

5. 2023 Liu KY,Kuo IP,Chen YJ,Lee PT,Lee CJ. Oral administration of tilapia hydrolysate peptides ameliorates the immune-related side effects of cyclophosphamide in BALB/c mice. . Food Bioscience .2023

6. 2023 Shiah HS,Lee CJ,Lee FY,Tseng SH,Chen SH,Wang CC. Chemopreventive effects of Xiang Sha Liu Jun Zi Tang on paclitaxel-induced leucopenia and neuropathy in animals. . Frontiers in Pharmacology .2023

7. 2022 Alinafe Magret Kapelemera,Yow-Shieng Uang,Li-Hsuan Wang,Tien-Yuan Wu,Fang-Yu Lee,Li Tai, Ching-Chiung Wang, Chia-Jung Lee. Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes . Frontiers in Pharmacology .2022 ;(13)

8. 2022 Tsai PW ,Hsieh CY ,Ting Jasmine U. ,Ciou YR,Lee CJ,Hsieh CL, Lien TK, Hsueh CC, Chen BY. Synergistic deciphering of bioenergy production and electron transport characteristics to screen traditional Chinese medicine (TCM) for COVID- 19 drug development . Journal of the Taiwan Institute of Chemical Engineers .2022

9. 2022 Gilbert Aaron Lee,Hong-Wei Zhao,Yu-Wei Chang,Chia-Jung Lee,Yu-Chen S. H. Yang,Ying-Chieh Wu, Wan-Li Lin, Yun-Ru Liu,De-Shan Ning, Sung-Hui Tseng. KI Essence extract (a spleen-tonifying formula) promotes neurite outgrowth, alleviates oxidative stress and hypomyelination, and modulates microbiome in maternal immune activation offspring . Frontiers in Pharmacology .2022

10. 2022 Yan-Feng Chen,Wen-Ru Chang,Chia-Jung Lee,Chih-Wei Chiu. Triangular gold nanoplates/two-dimensional nano mica platelets with 3D lightning-rod effect as flexible nanohybrid substrate for SERS bacterial detection . Journal of Materials Chemistry B .2022

11. 2022 Ning DS,Chen YJ,Lin CJ,Wang CC,Zhao HW,Wang KT, Lee MC, Lemmuel L. Tayo, Chiu WC, Yeh CL, Lee CJ. Hepatoprotective effect of botanical drug formula on high-fat diet-induced non-alcoholic fatty liver disease by inhibiting lipogenesis and promoting anti-oxidation . Frontiers in Pharmacology .2022

12. 2022 Hsieh CY,Wang CC,Tayo LL,Deng SX,Tsai PW,Lee CJ. In vitro and in vivo anti-osteoarthritis effects of tradition Chinese prescription Ji-Ming-San . Journal of Ethnopharmacology .2022

13. 2022 Tseng SH,Lee CJ,Chen SH,Chen CH,Tsai PW,Hsieh MS, Chu JS, Wang CC. Cinnamic aldehyde, an anti-inflammatory component in Du-Huo-Ji- Sheng-Tang, ameliorates arthritis in II collagenase and monosodium iodoacetate induced osteoarthritis rat models . Journal of Traditional and Complementary Medicine .2022

14. 2021 Cheng YH,Lee CJ,Chang CY. Achieving High Power Density and Long-Term Stable Flexible Triboelectric Nanogenerators through Surface Functionalization of High Work-Function Electrode with Cationic Thiol-Based Self-Assembled Monolayer. . Advanced Materials Technologies .2021 ;(6):2000985-2000985

15. 2021 Yang JR,Lee CJ,Chang CY. An electrostatically self-assembled fluorinated molecule as a surface modification layer for a high-performance and stable triboelectric nanogenerator. . Journal of Materials Chemistry A .2021 ;(9):4230-4239

16. 2020 Liu YH,Lee CJ,Chen LC,Lee TL,Hsieh YY,Han CH, Yang CH, Huang WJ, Hou WC. Acetylcholinesterase inhibitory activity and neuroprotection in vitro, molecular docking, and improved learning and memory functions of demethylcurcumin in scopolamine-induced amnesia ICR mice . Food & Function .2020 ;(11):2328-2338

17. 2020 Lee CJ,Huan KH,Lee YH,Yeh YS,Lin IH,Wang CC. Prescription patterns of Wu Lin San concentrated extract product for cystitis in Taiwan: A population-based study . Evidence-Based Complementary and Alternative Medicine .2020

18. 2020 Lee CJ,Alinafe Magret Kapelemera,Tsai YZ,Lee CT,Xu MY,Wang CC. Evaluating the therapeutic efficacy of Si-Wu-Tang decoction and concentrated extract in follicular maldevelopment-related menstrual disorders through pharmacokinetic/pharmacodynamic studies . Frontiers in Pharmacology .2020 ;(11):1245-1245

19. 2020 Chen LW,Chung HL,Wamg CC,Su JH,Chen YJ,Lee CJ. Anti-Acne Effects of Cembrene Diterpenoids from the Cultured Soft Coral Sinularia flexibilis . Marine Drugs .2020

20. 2020 Lee CJ,Huang CW,Chen LG,Wang CC. (+)-erythro-Δ8’-7S,8R-Dihydroxy-3,3’,5’-trimethoxy-8- O-4’-neolignan, an anti-acne component in degreasing Myristica fragrans Houtt . Molecules .2020 ;(25):4563-4563

21. 2020 Lu YL,Lee CJ,Lin SY,Hou WC. Reductions of copper ion-mediated low-density lipoprotein (LDL) oxidations of trypsin inhibitors, the sweet potato root major proteins, and LDL binding capacities . Botanical Studies .2020 ;(61):26-26

22. 2019 Huang GC,Tsai YZ,Lee CJ,Chang HY, Wang CC. Elucidation of the Effects of Si-Wu Tang on Menstrual Disorder Patterns through Activation of Aromatase and Antioxidation . Evidence-based Complementary and Alternative Medicine .2019 ;(2019):4761651-4761651

23. 2018 Lee CJ,Chen LG,Liang WL,Hsieh MS,Wang CC. Inhibitory effects of punicalagin from Punica granatum against type II collagenase-induced osteoarthritis . Journal of Functional Foods .2018 ;(41):216-222

24. 2018 Tsai PW, Lee YH, Chen LG, Lee CJ, Wang CC. In Vitro and In Vivo Anti-Osteoarthritis Effects of 2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-Glucoside from Polygonum Multiflorum . Molecules .2018 ;(23):571-581

25. 2017 Lee CJ,Chen LG,Liang WL,Wang CC. Multiple Activities of Punica granatum Linne against acne vulgaris . International Journal of Molecular Sciences .2017 ;(18):141-152

26. 2016 Huang GC,Chen SY,Tsai PW,Gannon Jerome G.,Lee CJ,Shiah HY, Wang CC. Effects of Dang-Gui-Bu-Xue-Tang, an herbal decoction, on iron uptake in iron-deficient anemia . Drug Design, Development and Therapy .2016 ;(10):949-957

27. 2016 Chien TY,Huang SK,Lee CJ,Tsai PW,Wang CC. Antinociceptive and anti-Inflammatory effects of zerumbone against mono-iodoacetate induced arthritis . International Journal of Molecular Sciences .2016 ;(17):pii: E

28. 2014 Lee CJ,Hsueh TY,Lin LC,Tsai TH. Determination of protein-unbound rhynchiphylline brain distribution by microdialysis and ultra-performance liquid chromatography with tandem mass spectrometry . Biomedical Chromatography .2014 ;(28):901-906

29. 2014 Lee CJ,Wu YT,Hsueh TY,Lin LC,Tsai TH. Pharmacokinetics and oral bioavailability of epimedin C after oral administration of epimedin C and Herba Epimedii extract in rats . Biomedical Chromatography .2014 ;(28):630-636

30. 2014 Tsai CF,Wang KT,Chen LG,Lee CJ,Tseng SH,Wang CC. Anti-inflammatory effects of Vitis thunbergii var. taiwaniana on knee damage associated with arthritis . Journal of Medicinal Food .2014 ;(17):479-486

31. 2013 Huang GC,Lee CJ,Wang KT,Weng BC,Chien TY,Tseng SH, Wang CC. Immunomodulatory effects of Hedysarum polybotrys extract in macrophage, splenocytes and leucopenia mice . Molecules .2013 ;(18):14862-14875

32. 2013 Chang-Liao WL,Hou ML,Chang LW,Lee CJ,Tsai YM,Lin LC, Tsai TH. Determination and pharmacokinetics of di-(2-ethylhexyl) phthalate in rats by ultra-performance liquid chromatography with tandem mass spectrometry . Molecules .2013 ;(18):11452-11466

33. 2013 Lee CJ,Chen LW,Chen LG,Chang TL,Huang CW,Huang MC, Wang CC. Correlations of the components of tea tree oil with its antibacterial effects and skin irritation . Journal of Food and Drug Analysis .2013 ;(21):169-176

34. 2012 Huan SK,Wang KT,Lee CJ,Sung CH,Chien TY,Wang CC. Wu-Chia-Pi solution attenuates carbon tetrachloride-induced hepatic injury through the antioxidative abilities of its components, acteoside and quercetin . Molecules .2012 ;(17):14673-14684

35. 2012 Huan SK,Wang KT,Yeh SD,Lee CJ,Lin LC,Liu DZ, Wang CC. Scutellaria baicalensis alleviates cantharidin-induced rat hemorrhagic cystitis through inhibition of cyclooxygenase-2 overexpression . Molecules .2012 ;(17):6277-6289

36. 2011 Hsieh MS,Wang KT,Tseng SH,Lee CJ,Chen CH,Wang CC. Using 18F-FDG microPET imaging to measure the inhibitory effects of Clematis chinensis Osbeck on the pro-inflammatory and degradative mediators associated with inflammatory arthritis . Journal of Ethnopharmacology .2011 ;(136):511-517

37. 2011 Lee CJ,Chen LG,Chang TL,Ke WM,Lo YF,Wang CC. The correlation between skin-care effects and phytochemical contents in Lamiaceae plants . Food Chemistry .2011 ;(124):833-841

38. 2010 Lee CJ,Chen LG,Liang WL,Wang CC. Anti-inflammatory effects of Punica granatum Linne in vitro and in vivo . Food Chemistry .2010 ;(118):315-322

39. 2009 Chen LG,Chang WL,Lee CJ,Lee LT,Shih CM,Wang CC. Melanogenesis inhibition by gallotannins from Chinese galls in B16 mouse melanoma cells . Biological and Pharmaceutical Bulletin .2009 ;(32):1447-1452

40. 2008 Chien TY,Chen LG,Lee CJ,Lee FY,Wang CC. Anti-inflammatory constituents of Zingiber zerumbet . Food Chemistry .2008 ;(110):584-589

41. 2005 Chao SH,Wu AB,Lee CJ,Chen FA,Wang CC. Anti-inflammatory effects of indomethacin's methyl ester derivative and induction of apoptosis in HL-60 cells . Biological and Pharmaceutical Bulletin .2005 ;(28):2206-2210

研究計畫

計畫名稱
113 香砂六君子湯及其相關配伍與西藥併用對CYP酵素影響之共性規律研究(3/3)
補助單位
國家科學及技術委員會

計畫名稱
112 玩美孩子王-離島社會處方實驗計畫
補助單位
農業部農村發展及水土保持署

計畫名稱
112 重組蛋白藥物於雄性禿之生髮可能性評估試驗研究計畫
補助單位
寶血純化科技股份有限公司

計畫名稱
112 香砂六君子湯及其相關配伍與西藥併用對CYP酵素影響之共性規律研究(2/3)
補助單位
國家科學及技術委員會

計畫名稱
112 中醫藥精準健康照護之實證研究-中藥複方治療異位性皮膚炎之療效評估暨免疫調節機轉、代謝體學及藥物動力學探討(3/3)
補助單位
國家科學及技術委員會

計畫名稱
112 貴機構依本會「補助國內研究生出席國際學術會議」申請費 用補助案(研究生:生藥學研究所碩士班楊承祐君)
補助單位
國家科學及技術委員會

計畫名稱
111 112年度「補助博士生赴國外研究」計畫(千里馬)-謝承洋
補助單位
國家科學及技術委員會

計畫名稱
111 玩美孩子王-離島社會處方實驗計畫
補助單位
農業部農村發展及水土保持署

計畫名稱
111 香砂六君子湯及其相關配伍與西藥併用對CYP酵素影響之共性規律研究(1/3)
補助單位
國家科學及技術委員會

計畫名稱
111 中醫藥精準健康照護之實證研究-中藥複方治療異位性皮膚炎之療效評估暨免疫調節機轉、代謝體學及藥物動力學探討(2/3)
補助單位
國家科學及技術委員會

計畫名稱
111 貴機構依本會「補助國內研究生出席國際學術會議」申請費用補助案(研究生:中草藥臨床藥物研發博士學位學程博士班謝承洋君)
補助單位
國家科學及技術委員會

計畫名稱
110 中醫藥精準健康照護之實證研究-中藥複方治療異位性皮膚炎之療效評估暨免疫調節機轉、代謝體學及藥物動力學探討(1/3)
補助單位
國家科學及技術委員會

計畫名稱
109 探討夜交藤萃取物合併Amoxicillin對於胃潰瘍的治療機制
補助單位
科技部

計畫名稱
109 穿戴式血糖監測開發研究計畫
補助單位
泰博科技股份有限公司

計畫名稱
109 臺灣鯛水解胜肽之特性分析與抗癌藥物之輔助療法
補助單位
臺北醫學大學

計畫名稱
108 抑制痤瘡桿菌生長之體內外試驗
補助單位
康品科技有限公司

計畫名稱
108 高脂飼料誘導脂肪肝之護肝功能評估
補助單位
禾百安科技股份有限公司

計畫名稱
107 金昭本草菁萃護肝之功效評估案
補助單位
禾百安科技股份有限公司

計畫名稱
107 海水產品之抑制胃幽門螺旋桿菌功能評估試驗計畫
補助單位
世台管理顧問股份有限公司

計畫名稱
106 常用中藥與抗生素之交互作用評估
補助單位
科技部

計畫名稱
106 鹿茸組合物產品之骨質保健 健康食品功效評估
補助單位
立康生物科技股份有限公司

計畫名稱
105 建立(E)-15,15-diethoxylabda-8(17),12-dien-16-al標準分離流程
補助單位
瑞諾華生醫股份有限公司

計畫名稱
105 科技栽培之石斛藥材生醫利用開發計畫
補助單位
創生投資股份有限公司

計畫名稱
105 白及配方對肺纖維化改善之評估
補助單位
和和實業股份有限公司

計畫名稱
105 106年度「中西藥交互作用實證資料探討分析」
補助單位
衛生福利部

計畫名稱
103 TMU103-AE1-B38
補助單位
臺北醫學大學

計畫名稱
103 (103)新聘教師專題研究計劃-李佳蓉教師
補助單位
臺北醫學大學