陳明堯(Chen, Ming-Yao) 助理教授

Email
u90223@tmu.edu.tw
現   職
內科學科 助理教授
消化醫學研究中心 副主任

學經歷

學 歷

畢業學校與學位[修業時間]
臺灣大學臨床醫學研究所 碩士
2010/09~2012/06
中國醫藥大學醫學系 學士
1994/09~2001/06

本校學術經歷

任職單位與職稱[起迄時間]
內科學科助理教授
2022/03/25~

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
消化醫學研究中心副主任
2023/08/01 ~

其它經歷

任職單位與職稱[起迄時間]
雙和醫院消化內科主治醫師

專長與研究領域

學門領域
醫學
Medical Science
消化醫學
Gastroenterological Medicine
肝膽胃腸
Hepatology and Gastrointestinal Medicine
學術專長
分子生物學
分子生物學
肝癌
肝癌
消化道內視鏡
消化道內視鏡
腸胃癌症
腸胃癌症

論文著作

清冊下載


1. 2024 Ming-Shou Hsieh, Ming-Yao Chen,Yu-Sheng Chang, Chin-Sheng Huang,Tung-Nien Hsu,Mao-Suan Huang, Chi-Tai Yeh, Yew-Min Tzeng. Targeting the Neuropilin-1 receptor with Ovatodiolide and progress in using periodontal ligament organoids for COVID-19 research and therapy . Life science .2024

2. 2023 Chen Ming Yao,Hsu Chia Hung,Setiawan Syahru Agung,Tzeng David T.W.,Ma Hon Ping,Ong Jiann Ruey,Chu Yi Cheng,Hsieh Ming Shou,Wu Alexander T.H.,Tzeng Yew Min,Yeh Chi Tai,Chen Ming Yao,Hsu Chia Hung,Setiawan Syahru Agung,Tzeng David T.W.,Ma Hon Ping,Ong Jiann Ruey,Chu Yi Cheng,Hsieh Ming Shou,Wu Alexander T.H.,Tzeng Yew Min,Yeh Chi Tai. Ovatodiolide and antrocin synergistically inhibit the stemness and metastatic potential of hepatocellular carcinoma via impairing ribosome biogenesis and modulating ERK/Akt-mTOR signaling axis . Phytomedicine .2023 ;(108)

3. 2023 Chia-Hung Hsu,Pei-Wei Weng,Ming-Yao Chen,Chi-Tai Yeh,Syahru Agung Setiawan,Vijesh Kumar Yadav, Alexander T H Wu, David T W Tzeng, Jian-Xian Gong, Zhen Yang, Yew-Min Tzeng. Therapeutic targeting of hepatocellular carcinoma cells with antrocinol, a novel, dual-specificity, small-molecule inhibitor of the KRAS and ERK oncogenic signaling pathways . Chemico-Biological Interactions .2023

4. 2023 Chun-Hung Chiu,Ming-Yao Chen,Jun-Jie Lieu,Chin-Chu Chen,Chun-Chao Chang,Charng-Cherng Chyau, Robert Y. Peng. Inhibitory Effect of Styrylpyrone Extract of Phellinus linteus on Hepatic Steatosis in HepG2 Cells . International Journal of Molecular Sciences .2023 ;(24):3672

5. 2023 Wen-Rui Hao,Tsung-Lin Yang,Yu-Hsin Lai ,Kuan-Jie Lin,Yu-Ann Fang,Ming-Yao Chen, Min-Huei Hsu , Chun-Chih Chiu, Tsung-Yeh Yang, Chun-Chao Chen, Ju-Chi Liu. The Association between Influenza Vaccine and Risk of Chronic Kidney Disease/Dialysis in Patients with Hypertension . Vaccines (Basel) .2023 ;(11):1098

6. 2023 Ting-Yun Huang, Ching-Kuo Yang, ,Ming-Yao Chen,Vijesh Kumar Yadav, Iat-Hang Fong,Chi-Tai Yeh,Yih-Giun Cherng. Furanocoumarin Notopterol: Inhibition of Hepatocellular Carcinogenesis through Suppression of Cancer Stemness Signaling and Induction of Oxidative Stress-Associated Cell Death . Nutrients .2023 ;(15):2447

7. 2023 Chung-Ying Lee,Tung-Cheng Chang,Ming-Yao Chen. Snare-tipped endoscopic radical incision and cutting for postoperative colorectal anastomotic stricture . Endoscopy .2023 ;(55):E1168-E1169

8. 2023 Meng-Chuan Lu,Chun-Chao Chen ,Meng-Ying Lu ,Kuan-Jie Lin,Chun-Chih Chiu,Tsung-Yeh Yang, Yu-Ann Fang, William Jian, Ming-Yao Chen, Min-Huei Hsu, Yu-Hsin Lai, Tsung-Lin Yang, Wen-Rui Hao, Ju-Chi Liu. The Association between Statins and Liver Cancer Risk in Patients with Heart Failure: A Nationwide Population-Based Cohort Study . Cancers (Basel) .2023 ;(15):2959

9. 2023 Chun-Chao Chen,Wen-Rui Hao,Hong-Jye Hong, Kuan-Jie Lin,Chun-Chih Chiu,Tsung-Yeh Yang, Yu-Ann Fang, William Jian, Ming-Yao Chen, Min-Huei Hsu, Shih-Chun Lu, Yu-Hsin Lai, Tsung-Lin Yang, Ju-Chi Liu. Protective Effects of Influenza Vaccine against Colorectal Cancer in Populations with Chronic Kidney Disease: A Nationwide Population-Based Cohort Study . Cancers (Basel) .2023 ;(15):23989

10. 2023 Hsin-Lun Lee, Yi-Chieh Tsai,Narpati Wesa Pikatan, Chi-Tai Yeh,Vijesh Kumar Yadav,Ming-Yao Chen, Jo-Ting Tsai. Tumor-Associated Macrophages Affect the Tumor Microenvironment and Radioresistance via the Upregulation of CXCL6/CXCR2 in Hepatocellular Carcinoma . Biomedicines .2023 ;(11):2028

11. 2023 Shiue-Wei Lai,Yi-Chiao Cheng,Wen-Chien Huang,Vijesh Kumar Yadav,Iat-Hang Fong,Chi-Tai Yeh, Ching-Kuo Yang, Wei-Hwa Lee, Ming-Yao Chen . Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis . Aging (Albany NY) .2023 ;(15):11033-11051

12. 2022 Hsin-Yun Wu,Chuen-Chau Chang,Chun-Chieh Yeh,Ming-Yao Chen,Yih-Giun Cherng,Ta-Liang Chen, Chien-Chang Liao. Adverse outcomes after non-hepatic surgeries in patients with alcoholic liver diseases: a propensity-score matched study . BMC Gastroenterology .2022 ;(22):475

13. 2022 s Yi C. Chu,Sheng-Tsai Lin,Syahru A. Setiawan,Ming-Shou Hsieh,Vijesh K. Yadav,Ting-Yi Huang, Chi-Tai Yeh, Ming-Yao Chen. Phenethyl isothiocyanate inhibits CD133+/CD90+ liver cancer stem cells by modulation of microRNA-214-β-catenin epigenome axis . Advanced in digestive medicine .2022

14. 2021 Chen Ming Yao,Yadav Vijesh Kumar,Chu Yi Cheng,Ong Jiann Ruey,Huang Ting Yi,Lee Kwai Fong,Lee Kuen Haur,Yeh Chi Tai,Lee Wei Hwa,Chen Ming Yao,Yadav Vijesh Kumar,Chu Yi Cheng,Ong Jiann Ruey,Huang Ting Yi,Lee Kwai Fong,Lee Kuen Haur,Yeh Chi Tai,Lee Wei Hwa. Hydroxychloroquine (Hcq) modulates autophagy and oxidative dna damage stress in hepatocellular carcinoma to overcome sorafenib resistance via tlr9/sod1/hsa-mir-30a5p/beclin-1 axis . Cancers .2021 ;(13)

15. 2021 Lai Shiue Wei,Chen Ming Yao,Bamodu Oluwaseun Adebayo,Hsieh Ming Shou,Huang Ting Yi,Yeh Chi Tai,Lee Wei Hwa,Cherng Yih Giun,Lai Shiue Wei,Chen Ming Yao,Bamodu Oluwaseun Adebayo,Hsieh Ming Shou,Huang Ting Yi,Yeh Chi Tai,Lee Wei Hwa,Cherng Yih Giun. Exosomal lncRNA PVT1/VEGFA Axis Promotes Colon Cancer Metastasis and Stemness by Downregulation of Tumor Suppressor miR-152-3p . Oxidative Medicine and Cellular Longevity .2021 ;(2021)

16. 2021 Yi Cheng Chu,Tung-Yao Tsai,Vijesh Kumar Yadav,Li Deng,Chun-Chih Huang,Yew-Min Tzeng, Chi-Tai Yeh, Ming-Yao Chen. 4-acetyl-antroquinonol b improves the sensitization of cetuximab on both kras mutant and wild type colorectal cancer by modulating the expression of Ras/Raf/miR-193a-3p signaling axis . International Journal of Molecular Sciences .2021 ;(22)

17. 2019 Lee Chung Ying,Kao Bi Zhen,Wu Chia Shin,Chen Ming Yao,Chien Hsi Yuan,Wu Li Wei,Lin Sheng Tsai,Lai Yu Hsin,Lin Hwai Jeng,Lee Chung Ying,Kao Bi Zhen,Wu Chia Shin,Chen Ming Yao,Chien Hsi Yuan,Wu Li Wei,Lin Sheng Tsai,Lai Yu Hsin,Lin Hwai Jeng. Retrospective analysis of endoscopic management of foreign bodies in the upper gastrointestinal tract of adults . Journal of the Chinese Medical Association .2019 ;(82):105-109

18. 2019 Ping-Jen Hu,Ming-Yao Chen,Ming-Shun Wu,Ying-Chin Lin,Ping-Hsiao Shih,Chih-Ho Lai, Hwai-Jeng Lin. Clinical Evaluation of CA72-4 for Screening Gastric Cancer in a Healthy Population: A Multicenter Retrospective Study . Cancers .2019 ;(11):733

19. 2018 Chung-Ying Lee,Ming-Yao Chen,Wan-Yu Wang. A rare complication of recurrent duodenal ulcer . Gastroenterology .2018 ;(155):e5-e6

20. 2018 Jia-Horng Kao,Min-Lung Yu,Chi-Yi Chen,Cheng-Yuan Peng,Ming-Yao Chen,Huoling Tang, Qiaoqiao Chen and Jinzi J Wu. Twelve-week ravidasvir plus ritonavir-boosted danoprevir and ribavirin for non-cirrhotic HCV genotype 1 patients: A phase 2 study . Journal of Gastroenterology and Hepatology .2018 ;(33):1507-1510

21. 2018 Hui-Chuan Huang,Kuan-Chia Lin,Chia-Shin Wu,Nae-Fang Miao,Ming-Yao Chen. Health-promoting behaviors benefit the mental health of cirrhotic outpatients. . Quality of Life Research .2018 ;(27):1521-1532

22. 2017 Ming-Yao Chen,Wen-Liang Fang,Kuo-Hung Huang,Yu-Hsin Lai,Hwai-Jeng Lin. Influence of high serum alpha fetoprotein on patients with gastric cancer . Advance in Digestive Medicine .2017 ;(4):50-53

23. 2016 Tung-Hung Su,Tsung-Hui Hu,Chi-Yi Chen,Yi-Hsiang Huang,Wan-Long Chuang,Chun-Che Lin, Chia-Chi Wang, Wei-Wen Su, Ming-Yao Chen, Cheng-Yuan Peng, Rong-Nan Chien, Yi-Wen Huang, Horng-Yuan Wang, Chih-Lin Lin, Sheng-Shun Yang, Tsung-Ming Chen, Lein-Ray Mo, Shih-Jer Hsu, Kuo-Chih Tseng, Tsai-Yuan Hsieh, Fat-Moon Suk, Chi-Tan Hu, Ming-Jong Bair, Cheng-Chao Liang, Yung-Chao Lei, Tai-Chung Tseng, Chi-Ling Chen, Jia-Horng Kao.. Four-year entecavir therapy reduces hepatocellular carcinoma, cirrhotic events and mortality in chronic hepatitis B patients. . Liver International .2016 ;(36):1755-1764

24. 2016 Shih-Hsin Tu,Ming-Yao Chen,Li-Ching Chen,Yi-Ting Mao,Chi-Hou Ho,Wen-Jui Lee, Yen-Kuang Lin, Min-Hsiung Pan, Chih-Yu Lo, Chi-Long Chen, Yun Yen, Jacqueline Whang-Peng, Chi-Tang Ho, Chih-Hsiung Wu, and Yuan-Soon Ho. Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study . Journal of Agricultural and Food Chemistry .2016 ;(64):3186-3195

25. 2016 Sheng-Tsai Lin,Shih-Hsin Tu,Po-Sheng Yang,Sung-Po Hsu,Wei-Hwa Lee,Chi-Tang Ho, Chih-Hsiung Wu, Yu-Hsin Lai, Ming-Yao Chen*, and Li-Ching Chen*. . Apple Polyphenol Phloretin Inhibits Colorectal Cancer Cell Growth via Inhibition of the Type 2 Glucose Transporter and Activation of p53-Mediated Signaling . Journal of Agricultural and Food Chemistry .2016 ;(64):6826-6837

26. 2014 Ming-Yao Chen,Chen-Hua Liu,Ting-Chih Chen,Tung-Hung Su,Pei-Jer Chen,Ding-Shinn Chen, Jia-Horng Kao, Chun-Jen Liu. Value of interleukin-28B genetic polymorphism on retreatment outcomes of chronic hepatitis C genotype 1 relapsers by peginterferon alfa plus ribavirin . Journal of Gastroenterology and Hepatology .2014 ;(29):102-109

27. 2008 Chen, M. Y,Cheng, Y-S,Lien, G-S,Chen, C. N,Suk, F-M,Wu, M-S. Ten Yeas' Experience of Percutaneous Endoscopic Gastrostomy . Gastroenterological Journal of Taiwan .2008 ;(25):373-381

研究計畫

計畫名稱
113 探討亮氨酰-tRNA 合成酶 1 (LARS1) 基因調控肝癌細胞內藥物代謝與鐵依賴性死亡在Regorafenib耐藥性之角色
補助單位
國家科學及技術委員會

計畫名稱
111 新聘教師研究補助
補助單位
臺北醫學大學

計畫名稱
109 探討奎寧及其衍生物改善非酒精性脂肪肝炎的效果及相關機轉
補助單位
健亞生物科技股份有限公司