陳淑惠(Chen, Shu-Huey ) 教授

Email
shu117@tmu.edu.tw
現   職
小兒學科 教授

學經歷

學 歷

畢業學校與學位[修業時間]
高雄醫學大學醫學系 學士
1980/09~1987/06

本校學術經歷

任職單位與職稱[起迄時間]
小兒學科教授
2024/08/01~
小兒學科副教授
2013/08/01~2024/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
小兒學科主任
2014/08/01 ~ 2020/07/31

其它經歷

任職單位與職稱[起迄時間]
慈濟大學醫學系小兒科副教授
2012/01/01~2013/06/28
慈濟大學醫學系小兒科助理教授
2008/08/01~2011/12/31
慈濟綜合醫院醫務部小兒部一般兒科主治醫師
2006/04/01~2013/06/28
馬偕紀念醫院小兒血液腫瘤科主治醫師
1987/07/01~2003/06/30

專長與研究領域

學門領域
學術專長

論文著作

清冊下載


1. 2024 Chou SC,YenCZ,Yang YL,Chen SH,Wang JD,Lin SW. Recapitulating the immune system of hemophilia A patients with inhibitors using immunodeficient mice . Thromb Res .2024

2. 2024 Syu WR, Liu YL,Miser JS,Kao MH,Chen SH. Autologous Peripheral Blood Stem Cell Harvest Timing by Absolute Neutrophil Count in Children and Young Adult Patients: Single-Institute . Pediatrics & Neonatology .2024 ;(S1875-9572(24)00127-X)

3. 2024 Lee CH, Shu-Huey Chen *,Hsu KW,Hsieh YY,Li WT,Long Y,Lin CY, Chen SH. Unveiling IL6R and MYC as Targeting Biomarkers in Imatinib-Resistant Chronic Myeloid Leukemia Through Advanced NIADS v2 Detection . Cells .2024 ;(13):616

4. 2024 Association Between Leg Muscle Thickness and Walking Test With the Hemophilia-Specific Functional Parameters . Am J Phys Med Rehabi .2024 ;(103):986-993

5. 2023 Chen SH,Miser JS,Liew PL,Chen BJ,Liu YL. Pulmonary lymphoepithelioma-like carcinoma: A complication of Epstein-Barr virus in a teenager . J Microbiol Immunol Infect .2023

6. 2023 Jia-Hui Huang, Shu-Huey Chen,Yu-Mei Liao ,Yu-Chien Kao,Wan-Ling Ho,Jia-Jia Tsai ,Yen-Lin Liu, Tai-Tong Wong, James S Miser. Feasibility and Toxicity of Interval-Compressed Chemotherapy in Asian Children and Young Adults with Sarcoma . J Pers Med .2023 ;(13):668-672

7. 2023 Shen MC Lin HY, Lee YC, Huang CE, D,Chou SC,,Chiou SS,Chen YC,Lin PC,Chen SH, Yu YB, Lin SC, Lin CY, Peng CT, Wang JD . Efficacy, safety and cost of emicizumab prophylaxis in haemophilia A patients with inhibitors: A nationwide observational study in Taiwan. . Haemophilia .2023 ;(29):1499-1508

8. 2023 Yu CH,Jou ST,Su YH,Wu KS,Cheng CN,Lin KH , Lu MY , Chen SH, Yang YL. Clinical impact of minimal residual disease and genetic subtypes on the prognosis of childhood acute lymphoblastic leukemia . Cancer .2023 ;(129):790-802

9. 2022 Lin PC,Chen SH,Wei CH,Kong SH,Chen SY. Peritoneal lymphomatosis presented with acute intermittent abdominal pain in a child . Pediatr Neonatol .2022

10. 2022 Yu CH,Wu G,Chang CH,JouST,Lu NY,LinKH ,ChenSH ,WuKH ,Huang FL. Sequential Approach to Improve the Molecular Classification of Childhood Acute Lymphoblastic Leukemia . J Mol Diagn . .2022 ;(24):11951-1206

11. 2022 Noppaket Singkham, Baralee Punyawudho,Ming-Sun Yu,Shin-Nan Cheng,Shu-Huey Chen,Hung Chang , Chih-Cheng Chen 8, Chih-Cheng Hsiao, Jen-Yin Hou , Yi-Ping Fang , Hsiang-Wei Wang , Jia-Hong Lin , Lennex Hsueh-Lin Yu , Yeu-Chin Chen . Influence of blood group and von Willebrand factor on population pharmacokinetics and dose individualization of recombinant factor VIII in Taiwanese patients with haemophilia . Haemophilia .2022 ;(28):230-238

12. 2022 Pei-Chun Lin,Yu-Chen S H Yang,Sheng-Chieh Lin,Meng-Che Lu,Yin-Tai Tsai ,Shou-Cheng Lu,Shu-Huey Chen ,Shih-Yen Chen. Clinical significance and intestinal microbiota composition in immunocompromised children with norovirus gastroenteritis . PLoS One .2022 ;(17)

13. 2021 Hsu YC,Yu CH,Chen YM,Roberts KG,Ni YL,Lin KH , ST Jou , MYLu , SH Chen . Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan . Sci Rep .2021 ;(11):5802

14. 2021 Chiu WC,Chen SH,Chen BJ,Huang YL,Miserc JS,Wei CHLin WC. Primary pulmonary Hodgkin's lymphoma: A rare etiology mimicking pulmonary tuberculosis. . Pediatr Neonatol .2021 ;(62):569-570

15. 2021 Yin YT, ,Tseng JH, ,Liu YL,, Miser JS,Chen SH. Neonatal acute lymphoblastic leukemia (MLL-AF9) with leukemia cutis. . Pediatr Neonatol. .2021 ;(62):676-678

16. 2021 Yang YL,Jaing TH,Chen SH,Liu HC, Hung IJ,Chen SH. Treatment outcomes of pediatric acute myeloid leukemia: a retrospective analysis from 1996 to 2019 in Taiwan . Sci Rep .2021 ;(11):5893-5898

17. 2021 Lin CL,Tsai ML,Chen YH, , Liu WN,Lin CY,Hsu KW, Huang CY, Chang YJ, Wei PL, Chen SH, Huang LC, Lee CH. Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo. . Biomol Ther (Seoul) .2021

18. 2020 Shu-Huey Chen,Yao-Yu Hsieh,Huey-En Tzeng,Su-Mei Lin,Chun-Yu Lin,Chia-Hwa Lee. ABL Genomic Editing Sufficiently Abolishes Oncogenesis of Human Chronic Myeloid Leukemia Cells In Vitro and In Vivo . Cancers .2020 ;(12):1399-1399

19. 2020 Chih-Hsiang Yu ,Tze-Kang Lin , Shiann-Tarng Jou, Chien-Yu Lin,Kai-Hsin Lin ,Shu-Huey Chen, Meng-Yao Lu, . MLPA and DNA index improve the molecular diagnosis of childhood B-cell acute lymphoblastic leukemia . Sci Rep .2020 ;(10):11501

20. 2020 Sung-Liang Yu ,Hui Zhang ,Bing-Ching Ho,Chih-Hsiang Yu,Kai-Hsin Lin,Meng-Yao Lu , Shu-Huey Chen ,. FPGS relapse-specific mutations in relapsed childhood acute lymphoblastic leukemia . Sci Rep .2020 ;(10):12074

21. 2020 Lin TC,Chen SH, Wu CC,Chang CY. Successful bleeding control of refractory hemothorax in two hemophilia A patients with high-titer inhibitors. . Pediatr Neonatol .2020 ;(61):361-363

22. 2020 Wei-Ching Chiu , Shu-Huey Chen, Mei-Chen Lo,Yung-Ting Kuo. Classic Ehlers-Dalnos syndrome presenting as atypical chronic haematoma: a case report with novel frameshift mutation in COL5A1 . BMC Pediatrics .2020 ;(20):495-500

23. 2020 Lin SC ,Tam KW,Lu MC ,Kao YT,Chen SY,Chen SH. The impact of shared decision making with patient decision aids on the rotavirus vaccination rate in children: A randomized controlled trial. . Prev Med .2020 ;(141)

24. 2019 Shu-Huey Chen ,Yung-Ting Kuo,Li-Ping Tsai,Yen-Lin Liu, James S. Miser. 2-year-old twin boy with pancytopenia caused by nutritional cobalamin deficiency . Pediatr Neonatol .2019 ;(60):598-599

25. 2019 Chen SH,Chow JM,Hsieh YY,Lin CY,, Hsu KW,Hsieh WS,Shabangu BM, Lee CH.. HDAC1, 2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells. . Int J Mol Sci. .2019 ;(20)

26. 2019 Chang YH, Chen C,Chen SH,Shen YC,, Kuo YT. Effectiveness of corticosteroids versus adrenocorticotropic hormone for infantile spasms: a systematic review and meta-analysis. . Ann Clin Transl Neurol .2019 ;(6):2270-2281

27. 2019 Yang, Yung-Li,Yu, Chih-Hsiang,Chang, Wan-Ting,Jou, Shiann-Tarng, Lin, Tze-Kang,Chen, Shu-Huey . P53 alterations in relapsed childhood acute lymphoblastic leukemia . Cancer Sci. .2019 ;(111):229-238

28. 2018 Huang PO,Liu YL,Miser JS,Lee CH,Kao CY,Chen SH. Carcinoid tumor arising from a retroperitoneal mature cystic teratoma. . Pediatr Neonatol. .2018 ;(59):520-522

29. 2018 Yeh TC,Liang DC,Hou JY,Jaing TH,Lin DT,Yang CP,Peng CT, Hung IJ, Lin KH, Hsiao CC, Jou ST, Chiou SS, Chen JS, Wang SC, Chang TK, Wu KH, Sheen JM, Yen HJ, Chen SH, Lu MY, Li MJ, Chang TT, Huang TH, Chang YH, Chen SH, Yang YL, Chang HH, Chen BW, Lin PC, Cheng CN, Chao YH, Yang SH, Chao YY, Liu HC.. Treatment of childhood acute lymphoblastic leukemia with delayed first intrathecal therapy and omission of prophylactic cranial irradiation: Results of the TPOG-ALL-2002 study. . Cancer .2018 ;(24):4538-4547-4547

30. 2017 Yen HJ,Chen SH,Chang TY,Yang CP,Lin DT,Hung IJ, Lin KH, Chen JS, Hsiao CC, Chang TT, Chang TK, Peng CT, Lin MT, Jaing TH, Liu HC, Jou ST, L. Pediatric acute lymphoblastic leukemia with t(1;19)/TCF3-PBX1 in Taiwan. . Pediatr Blood Cancer .2017

31. 2017 Chen SH,Kuo YT,Liu YL,Chen BJ,Lu YC,Miser JS. Acute Myeloid Leukemia Presenting with Sweet Syndrome: A Case Report and Review of the Literature . Pediatr Neonatol .2017 ;(58):283-284

32. 2016 Li MJ,Liu HC,Yen HJ,Jaing TH,Lin DT,Yang CP, Lin KH, Hung IJ, Jou ST, Lu MY, Hsiao CC, Peng CT, Chang TT, Wang SC, Lin MT, Chen JS, Chan. Treatment for childhood acute lymphoblastic leukemia in Taiwan: Taiwan Pediatric Oncology Group ALL-2002 study emphasizing optimal reinduction therapy and CNS preventive therapy without cranial radiation . Pediatr Blood Cancer .2016 ;(64):234-241

33. 2015 Chen MC,Yang SH,Yao TK,Chong PN,Chen SH. Bilateral hip pain due to adductor pyomyositis as the initial presentation of CML in a 17 year-old child . Pediatr and Neonatol .2015 ;(53):535-537

34. 2015 Lin WC,Shih PH,Wang W,Wu CH,Hsia SM,Wang HJ, Hwang PA, Wang CY, Chen SH, Kuo YT. Inhibitory effects of high stability fucoxanthin on palmitic acid-induced lipid accumulation in human adipose-derived stem cells through modulation of long non-coding RNA . Food Funct. .2015 ;(6):2215-2223

35. 2015 Chen SH,Fan CK,Miser JS,Liu YL,Huang YJ,Wang CY. An infant boy with widespread ecchymoses and severe eosinophilia . Journal of Microbiology, Immunology ans Infection .2015 ;(48):233-235

36. 2014 Chen SH,Liu YL,Hsu WM,Miser JS. Infants with Cancer: A Unique Population . Journal of Experimental and Clinical Medicine .2014 ;(6):1-9

37. 2014 Wang TF,Wen SH,Yang KL,Yang SH,Yang YF,Chang CY, Wu YF, Chen SH. Umbilical Cord Blood Donations in a Public Cord Blood Bank . Transfusion .2014 ;(54):231-237

38. 2014 Chen SH,Wang TF,Yang YL. Hematopoietic stem cell donation . Int J Hematol .2014 ;(97):446-455

39. 2013 Wang TF,Chen SH,Yang SH,Su YC,Chu SC,Li DK. Poor harvest of peripheral blood stem cell in donors with microcytic red blood cell . Transfusion .2013 ;(53):91-95

40. 2013 Chen SH,Yang SH,Chu SC,Su YC,Chang CY,Chiu YW, Kao RH, Li DK, Yang KL, Wang TF. The role of donor characteristics and post granulocyte colony-stimulating factor white blood cell counts in predicting the adverse events and yields of stem cell mobilization . Int J Hematol .2013 ;(93):652-659

41. 2012 Chen SH,Lin M,Yang KL,Lin TY,Tsai HH,Shang-Hsien Yang SH, Chang YH, Wu YF, Wang TF. Association of ABO Incompatibility with Red Blood Cell Indices of Cord Blood Unit . Pediatr and Neonatol .2012 ;(53):138-143

42. 2012 Lai PC,Chen SH,Yang SH,Cheng CC,Chiu TH,Huang YT. Novel Survivin Inhibitor YM155 elicits cytotoxicity in glioblastoma cell lines with normal or deficiency DNA-dependent protein kinase activity . Pediatr and Neonatol .2012 ;(53):199-204

43. 2011 Chen SH,Yang SH,Chu SC,Tsai SS,Chang CY,Chiu YW, Su YC, Yang KL, Shyr MH, Wang TF. Second donation from volunteer hematopoietic stem cell donors in Taiwan . Tzu Chi Medical Journal .2011 ;(23):16-19

44. 2011 Chang YH,Yang SH,Wang TF,Lin TY,Yang KL,Chen SH. Complete Blood Count Reference Values of Cord Blood in Taiwan and their Influence by Gender and Delivery Route . Pediatr and Neonatol .2011 ;(52):155-160

45. 2011 Wang TF,Chu SC,Chen SH,Huang KP,Su YC,Li DK, Shyr MH, Chang CY, Tsai SS, Kao RH. The Effect of Different Harvest Strategies on the Nucleated Cell Yields of Bone Marrow Collection . Biology of Blood and Marrow Transplantation .2011 ;(2011):351-355

46. 2010 Yang SH,Wang TF,Tsai HH,Lin TY,Wen SH,Chen SH. Pre-harvest Hematopoietic Progenitor Cell Count Predict CD34+ Cell Yields in G-CSF-induced Peripheral Blood Stem Cell Mobilization in Healthy Donors . Transfusion .2010 ;(50):1088-1095

研究計畫

計畫名稱
112 利用全基因組剔除研究平台(Genome- scale CRISPR-Cas9 knockout,GeCKO)與活體動物高轉移乳 癌模式評估RELN和COX7B2基因作為三陰 性乳癌轉移標靶潛力探討
補助單位
國家科學及技術委員會

計畫名稱
112 以CRISPR/Cas9基因剔除及調控甲基轉移 酶與 AML M5急性骨髓性白血病細胞之癌 症侵襲性相關性案討
補助單位
國家科學及技術委員會

計畫名稱
112 以全基因組剔除(GeCKO)分析模式探討人類瀰漫性大B細胞淋巴瘤(DLBCL)新穎標靶抗癌有效性分析
補助單位
國家科學及技術委員會

計畫名稱
111 以外泌體介導CAR-T免疫細胞療法發展新穎性瀰漫性大B細胞淋巴癌抗癌模式
補助單位
國家科學及技術委員會

計畫名稱
111 藉由全基因編輯篩選平台開發人類瀰漫大B細胞淋巴瘤標靶治療模式
補助單位
國家科學及技術委員會

計畫名稱
110 以CRISPR/Cas9基因編輯平台發展MYC/BCL2/BCL6作為人類B細胞淋巴癌標靶精準治療模式
補助單位
科技部

計畫名稱
108 以非侵入性細胞凋亡偵測平台開發血癌精準醫療研究模式-以CRISPR/Cas9基因與標靶治療費城染色體慢性骨髓性白血病為例
補助單位
科技部