1. |
2024
Identifying the role of MTHFD1L in prostate cancer progression from genetic analysis and experimental validation
. Am J Cancer Res .
.2024
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2. |
2023
Bui QH,Lee KD,Fan YC,Lewis BS,Deng LW,Tsai YC.
Disruption of CCL2 in Mesenchymal Stem Cells as an Anti-Tumor Approach against Prostate Cancer
. Cancers
.2023
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3. |
2023
Tumor-derived interleukin-1 receptor antagonist exhibits immunosuppressive functions and promotes pancreatic cancer
. Cell & Bioscience
.2023
;(13)
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4. |
2021
Tsai YC,Huang CY,Hsueh YM,Fan YC,Fong YC,Huang SP, Geng JH, Chen LC, Lu TL, Bao BY.
Genetic variants in MAPK10 modify renal cell carcinoma susceptibility and clinical outcomes
. Life Sci
.2021
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5. |
2021
Yu-Ching Fan, Kai-Chen Hsu, Tony-Eight Lin,Dietmar Zechner, Sung-Po Hsu,Yuan-Chin Tsai.
Investigation of Anti-Tumor Effects of an MLK1 Inhibitor in Prostate and Pancreatic Cancers
. Biology (Basel).
.2021
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6. |
2020
Yu-Ching Fan, Wei-Yu Chen, Kuan-Der Lee,Yuan-Chin Tsai.
Tumor-infiltrating Leukocytes Suppress Local Inflammation Via Interleukin-1 Receptor Antagonist in a Syngeneic Prostate Cancer Model
. Biology(Basel)
.2020
;(9)
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7. |
2020
Fan YC,Lee KD,Tsai YC.
Roles of Interleukin-1 Receptor Antagonist in Prostate Cancer Progression
. biomedicines
.2020
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8. |
2018
Tsai YC,Zeng T,Abou-Kheir W,Yeh HL,Yin JJ,Lee YC, Chen WY, Liu YN.
Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer
. Molecular Cancer
.2018
;(17):42-42
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9. |
2018
Tsai YC,Chen WY,Abou-Kheir W,Zeng T,Yin JJ,Bahmad H, Lee YC, Liu YN.
Androgen deprivation therapy-induced epithelial-mesenchymal transition of prostate cancer through downregulating SPDEF and activating CCL2
. BBA - Molecular Basis of Disease
.2018
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10. |
2018
Zhong WB,Tsai YC,Chin LH,Tseng JH,Tang LW,Horng S, Fan YC, Hsu SP.
A Synergistic Anti-Cancer Effect of Troglitazone and Lovastatin in a Human Anaplastic Thyroid Cancer Cell Line and in a Mouse Xenograft Model.
. Int J Mol Sci.
.2018
;(19)
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11. |
2017
Chen MC,Tsai YC,Tseng JH,Liou JJ,Horng S,Wen HC, Wen HC, Fan YC, Zhong WB, Hsu SP.
Simvastatin Inhibits Cell Proliferation and Migration in Human Anaplastic Thyroid Cancer.
. International Journal of Molecular Sciences
.2017
;(18)
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12. |
2017
Tsai YC,Chen WY,Tsai HY,Siu MK,Yin JJ,Huang J, and Liu YN.
Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6
. Cancer letters
.2017
;(384):1-8
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13. |
2017
Man KS,Chen WY,Tsai HY,Chen HY,Yin JJ,Chen CL Tsai YC, Liu YN.
TCF7 is suppressed by the androgen receptor via microRNA-1-mediated downregulation and is involved in the development of resistance to androgen deprivation in prostate cancer
. Prostate cancer and prostatic diseases
.2017
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14. |
2017
Chen WY,Tsai YC,Siu MK,Yeh HL,Chen CL,Yin YY, Huang J, and Liu YN.
Inhibition of the androgen receptor induces a novel tumor promoter, ZBTB46, for prostate cancer metastasis
. Oncogene
.2017
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15. |
2017
Chen WY,Tsai YC,Yeh HL,Suau F,Jiang KC,Shao AN, Huang J, Liu YN.
Loss of SPDEF and gain of TGFBI activity after androgen deprivation therapy promote EMT and bone metastasis of prostate cancer.
. Science Signaling
.2017
;(10)
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16. |
2017
Tsai YC,Liu YN.
New ideas in preventing castration-resistant prostate cancer.
. Oncotarget
.2017
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17. |
2016
Siu MK,Suau F,Chen WY,Tsai YC,Tsai HY,Yeh HL, Liu YN.
KLF4 functions as an activator of the androgen receptor through reciprocal feedback.
. Oncogenesis
.2016
;(5):e282
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18. |
2015
Siu MK,Tsai YC,Chang YS,Yin JJ,Suau F,Chen WY, Liu YN.
Transforming growth factor-β promotes prostate bone metastasis through induction of microRNA-96 and activation of the mTOR pathway.
. Oncogene
.2015
;(34):4767-4776
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19. |
2015
Rowles DL,Tsai YC,Greco TM,Lin AE,Li M,Yeh J, Cristea IM.
The DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV-1 infection.
. Proteomics
.2015
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20. |
2014
Tsai YC,Greco TM,Cristea IM.
Sirtuin 7 plays a role in ribosome biogenesis and protein synthesis
. Mol Cell Proteomics.
.2014
;(13):73-83
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21. |
2013
Tsai YC,Greco TM,Boonmee A,Miteva Y,Cristea IM.
Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.
. Mol Cell Proteomics
.2013
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22. |
2011
Lin RK,Zhou N,Lyu YL,Tsai YC,Lu CH,Kerrigan J, Chen YT, Guan Z, Hsieh TS, Liu LF.
Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.
. J Biol Chem
.2011
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23. |
2010
Azarova AM,Lin RK,Tsai YC,Liu LF,Lin CP,Lyu YL.
Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia.
. Biochem Biophys Res Commun
.2010
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24. |
2009
Tsai YC,Qi H,Lin CP,Lin RK,Kerrgan JE,Rzuczek SG, LaVoie EJ, Rice JE, Pilch DS, Lyu YL, Liu LF.
A G-quadruplex stabilizer induces M-phase cell cycle arrest.
. J Biol Che
.2009
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25. |
2009
Feng W,Satyanarayana M,Tsai YC,Liu AA,Liu LF,LaVoie EJ.
12-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridines as novel topoisomerase I-targeting antitumor agents.
. Bioorg Med Chem
.2009
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26. |
2009
Feng W,Satyanarayana M,Tsai YC,Liu AA,Liu LF,LaVoie EJ.
Novel topoisomerase I-targeting antitumor agents synthesized from the N,N,N-trimethylammonium derivative of ARC-111, 5H-2,3-dimethoxy-8,9-methylenedioxy-5-[(2-N,N,N-trimethylammonium)ethyl]dibenzo[c,h][1,6]naphthyridin-6-one iodide.
. Eur J Med Chem
.2009
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27. |
2009
Sharma L,Tsai YC,Liu AA,Liu LF,LaVoie EJ.
Cytotoxicity and TOP1-targeting activity of 8- and 9-amino derivatives of 5-butyl- and 5-(2-N,N-dimethylamino)ethyl-5H-dibenzo[c,h][1,6]naphthyridin-6-ones.
. Eur J Med Chem
.2009
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28. |
2008
Feng W,Satyanarayana M,Cheng L,Liu A,Tsai YC,Liu LF, LaVoie EJ.
Synthesis of N-substituted 5-[2-(N-alkylamino)ethyl]dibenzo[c,h][1,6]naphthyridines as novel topoisomerase I-targeting antitumor agents.
. Bioorg Med Chem.
.2008
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29. |
2008
Feng W,Satyanarayana M,Tsai YC,Liu AA,Liu LF,LaVoie EJ.
11-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridine derivatives as novel topoisomerase I-targeting agents.
. Bioorg Med Chem
.2008
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30. |
2008
Satyanarayana M,Feng W,Cheng L,Liu AA,Tsai YC,Liu LF, LaVoie EJ.
Syntheses and biological evaluation of topoisomerase I-targeting agents related to 11-[2-(N,N-dimethylamino)ethyl]-2,3-dimethoxy-8,9-methylenedioxy-11H-isoquino[4,3-c]cinnolin-12-one (ARC-31).
. Bioorg Med Chem
.2008
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