林育嬋(Lin, Yu-Charn) 助理教授

Email
yuhcharnlin@tmu.edu.tw
現   職
生理學科 助理教授

學經歷

學 歷

畢業學校與學位[修業時間]
國防醫學院生命科學研究所 博士
2009/08~2015/01
弘光科技大學生物科技研究所 碩士
2004/08~2006/06
弘光科技大學食品營養系 學士
2002/08~2004/06

本校學術經歷

任職單位與職稱[起迄時間]
生理學科助理教授
2022/07/25~

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
中央研究院生物醫學科學研究所研究學者
2020/08~2022/07
中央研究院生物醫學科學研究所助理研究學者
2018/08~2020/07
中央研究院博士後研究員
2015/01~2018/07
中央研究院研究助理
2008/03~2009/08

專長與研究領域

學門領域
學術專長
細胞訊息傳遞學
細胞訊息傳遞學
心臟血管生理學
心臟血管生理學
血管生物學
血管生物學
血管新生
血管新生
癌症分子醫學
癌症分子醫學

論文著作

清冊下載


1. 2024 Lin YC,Chang YJ,Gau SS,Lo CM,Yang RB. SCUBE2 regulates adherens junction dynamics and vascular barrier function during inflammation . Cardiovascular Research .2024

2. 2024 Lee KH,Lih YC,Tsai MT,Tu CF,Ou SM,Chen HY, Li FA, Tseng WC, Lin YP, Yang RB, Tarng DC. Plasma SCUBE2 as a novel biomarker associates with survival outcomes in patients with sepsis-associated acute kidney injury . Journal of microbiology, immunology, and infection .2024

3. 2023 Lin YC,Sahoo BK,Gau SS,Yang RB. The Biology of SCUBE . Journal of biomedical Science .2023

4. 2023 Dhawan U,Wang WL,Lin YC,Yang RB,Dalby MJ,Salmeron-Sanchez M, Yu HH. Mechanostimulation-induced integrin αvβ6 and Latency Associated Peptide coupling activates TGF-β and regulates cancer metastasis and stemness . Nano Today .2023

5. 2022 Sahoo BK,Lin YC,Tu CF,Lin CC,Liao WJ,Li FA, Li LH, Mou KY, Roffler SR, Wang SP, Yeh CT, Yao CY, Hou HA, Chou WC, Tien HF, Yang RB. Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia . Haematologica .2022

6. 2022 Tsao KC,Lin YC,Chen YT,Lai SL,Yang RB. Zebrafish Scube1 and Scube2 cooperate in promoting Vegfa signalling during embryonic vascularization . Cardiovascular Research .2022 ;(118):1074-1087

7. 2022 Liu Y,Guerrero-Juarez CF,Xiao F,Shettigar NU,Ramos R,Kuan CH, Lin YC, Luis de Jesus Martinez Lomeli, Park JM, Oh JW, Liu R, Lin SJ, Tartaglia M, Yang RY, Yu Z, Nie Q, Li J, Plikus MV. Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state . Developmental Cell .2022 ;(57):1758-1775.e7

8. 2022 Chou PC,Liu CM,Weng CH,Yang KC,Cheng ML,Lin YC, Yang RB, Shyu BC, Shyue SK, Liu JD, Chen SP, Hsiao M, Hu YF. Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes . Circulation Research .2022 ;(131):6-20

9. 2022 Hu YF,Lee AS,Chang SL,Lin SF,Weng CH,Lo HY, Chou PC, Tsai YN, Sung YL, Chen CC, Yang RB, Lin YC, Kuo BJ, Wu CH, Liu JD, Chung TW, Chen SA. Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats . Nature Biomedical Engineering .2022 ;(6):421-434

10. 2021 Lin YC,Niceta M,Muto V,Vona B,Pagnamenta AT,Maroofian R, Beetz C, Duyvenvoorde HV, Dentici ML, Lauffer P, Vallian S, Ciolfi A, Pizzi S, Bauer P, Gruning NM, Bellacchio E, Fattore AD, Petrini S, Shaheen R, Tiosano D, Halloun R, Pode-Shakked B, Albayrak HM, Isik E, Wit JM, Dittrich M, Freire BL, Bertola DR, Jorge AAL, Barel O, Sabir AH, Tenaiji AMJA, Taji SM, Al-Sannaa N, Al-Abdulwahed H, Digilio MC, Irving M, Anikster Y, Bhavani GSL, Girisha KM, Genomics England Research Consortium, Haaf T, Taylor JC, Dallapiccola B, Alkuraya FS, Yang RB. SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling . American Journal of Human Genetics .2021 ;(108):1-19

11. 2018 Lin Yuh Charn,Liu Chun Yu,Kannagi Reiji,Yang Ruey Bing,Lin Yuh Charn,Liu Chun Yu,Kannagi Reiji,Yang Ruey Bing. Inhibition of endothelial SCUBE2 (signal peptide-CUB-EGF domain-containing protein 2), a Novel VEGFR2 (vascular endothelial growth factor receptor 2) coreceptor, suppresses tumor angiogenesis . Arteriosclerosis, Thrombosis, and Vascular Biology .2018 ;(38):1202-1215

12. 2018 Yeh Hsi Wen,Hsu En Chi,Lee Szu Shuo,Lang Yaw Dong,Lin Yuh Charn,Chang Chieh Yu,Lee Suz Yi,Gu De Leung,Shih Jou Ho,Ho Chun Ming,Chen Chian Feng,Chen Chiung Tong,Tu Pang Hsien,Cheng Ching Feng,Chen Ruey Hwa,Yang Ruey Bing,Jou Yuh Shan,Yeh Hsi Wen,Hsu En Chi,Lee Szu Shuo,Lang Yaw Dong,Lin Yuh Charn,Chang Chieh Yu,Lee Suz Yi,Gu De Leung,Shih Jou Ho,Ho Chun Ming,Chen Chian Feng,Chen Chiung Tong,Tu Pang Hsien,Cheng Ching Feng,Chen Ruey Hwa,Yang Ruey Bing,Jou Yuh Shan. PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis . Nature Cell Biology .2018 ;(20):479-491

13. 2018 Chen Jia Hong,Kuo Kuang Tai,Bamodu Oluwaseun Adebayo,Lin Yuh Charn,Yang Ruey Bing,Yeh Chi Tai,Chao Tsu Yi,Chen Jia Hong,Kuo Kuang Tai,Bamodu Oluwaseun Adebayo,Lin Yuh Charn,Yang Ruey Bing,Yeh Chi Tai,Chao Tsu Yi. Upregulated SCUBE2 expression in breast cancer stem cells enhances triple negative breast cancer aggression through modulation of notch signaling and epithelial-to-mesenchymal transition . Experimental Cell Research .2018 ;(370):444-453

研究計畫

計畫名稱
112 闡明SCUBE蛋白家族對血栓形成與心臟修復之分子機制(3/3)
補助單位
國家科學及技術委員會

計畫名稱
112 探究Galectin-9調控內皮細胞與巨噬細胞之交互作用影響慢性腎病變進程
補助單位
國家科學及技術委員會

計畫名稱
111 新聘教師研究補助
補助單位
臺北醫學大學

計畫名稱
111 闡明SCUBE蛋白家族對血栓形成與心臟修復之分子機制(2/3)
補助單位
國家科學及技術委員會