| 1. |
2024
Amandeep Thakur,Yi-Hsuan Chu,Chun-Hsu Pan,Kunal Nepali.
Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation
. European Journal of Medicinal Chemistry
.2024
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| 2. |
2024
Amandeep Thakur,Chun-Hsu Pan,Kunal Nepali.
Recent Advances and Future Directions on Small Molecule VEGFR Inhibitors in Oncological Conditions
. European Journal of Medicinal Chemistry
.2024
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| 3. |
2024
First-in-Class Dual EZH2-HSP90 Inhibitor Eliciting Striking Antiglioblastoma Activity In Vitro and In Vivo
. Journal of medicinal chemsitry
.2024
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| 4. |
2024
Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress
. Cancer Letters
.2024
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| 5. |
2024
Spleen tyrosine kinase (SYK): an emerging target for the assemblage of small molecule antitumor agents
. Expert Opinion on Investigational Drugs
.2024
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| 6. |
2024
Recent advances and future directions on small molecule VEGFR inhibitors in oncological conditions
. European Journal of Medicinal Chemistry
.2024
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| 7. |
2024
Rationally Designed Febuxostat-Based Hydroxamic Acid and its pH-Responsive Nanoformulation Elicits Anti-Tumor Activity
. European Journal of Medicinal Chemistry
.2024
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| 8. |
2024
Scaffold hopping approaches for dual-target antitumor drug discovery: opportunities and challenges
. Expert Opinion on Drug Discovery
.2024
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| 9. |
2024
Syntheses of LSD1/HDAC Inhibitors with Demonstrated Efficacy against Colorectal Cancer: In Vitro and In Vivo Studies Including Patient-Derived Organoids
. Journal of Medicinal Chemistry
.2024
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| 10. |
2023
Rationally designed donepezil-based hydroxamates modulate Sig-1R and HDAC isoforms to exert anti-glioblastoma effects
. European Journal of Medicinal Chemistry
.2023
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| 11. |
2023
Prudent tactics to sail the boat of PARP inhibitors as therapeutics for diverse malignancies
. EXPERT OPINION ON DRUG DISCOVERY
.2023
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| 12. |
2023
Small molecule tractable PARP inhibitors: Scaffold construction approaches, mechanistic insights and structure activity relationship
. Bioorganic chemistry
.2023
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| 13. |
2023
Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer
. Journal of Enzyme Inhibition and Medicinal Chemistry
.2023
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| 14. |
2023
Flavone-based dual PARP-Tubulin inhibitor manifesting efficacy against endometrial cancer
. Journal of Enzyme Inhibition and Medicinal Chemistry
.2023
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| 15. |
2023
Meet the Editorial Board Member - kunal nepali
. Mini-Reviews in Medicinal Chemistry
.2023
;(23):2-2
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| 16. |
2023
N-Heterocycle based Degraders (PROTACs) manifesting anticancer efficacy: Recent Advances
. Current drug targets
.2023
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| 17. |
2022
The Role of Epigenetic Mechanisms in Autoimmune, Neurodegenerative, Cardiovascular, and Imprinting Disorders.
. Mini Reviews in Medicinal Chemistry, 2022
.2022
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| 18. |
2022
Charanjit Kaur,Bhargavi Sharma,Kunal Nepali.
Switch Pocket Kinase: An Emerging Therapeutic Target for the Design of Anticancer Agents
. Anticancer agents in Medicinal chemistry
.2022
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| 19. |
2022
Rational design of synthetically tractable HDAC6/HSP90 dual inhibitors to destroy immune-suppressive tumor microenvironment
. Journal of Advanced Research
.2022
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| 20. |
2022
Glioblastoma: Current Status, Emerging Targets, and Recent Advances
. Journal of Medicinal Chemistry
.2022
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| 21. |
2022
Accommodation of ring C expanded deoxyvasicinone in the HDAC inhibitory pharmacophore culminates into a tractable anti-lung cancer agent and pH-responsive nanocarrier
. European Journal of Medicinal Chemistry
.2022
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| 22. |
2022
Kunal Nepali,Ram Sharma,Sachin Sharma,Amandeep Thakur,Jing Ping Liou.
Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal
. Journal of biomedical science
.2022
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| 23. |
2021
Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma
. European Journal of medicinal chemistry
.2021
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| 24. |
2021
A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling
. Biomedicine and Pharmacotherapy.
.2021
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| 25. |
2021
Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends
. Journal of biomedical sciences
.2021
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| 26. |
2021
Emerging Role of Terpenoids for the Treatment of Cancer: A Review
. Mini reviews in medicinal chemistry
.2021
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| 27. |
2021
The HDAC/HSP90 Inhibitor G570 Attenuated Blue Light-Induced Cell Migration in RPE Cells and Neovascularization in Mice through Decreased VEGF Production
. Molecules
.2021
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| 28. |
2021
Ritu ojha,I-Chung Chen,Chien-Ming Hsieh,Kunal Nepali.
Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent
. Journal of medicinal chemistry
.2021
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| 29. |
2020
Kunal Nepali,Ting-Yu Chang,Mei-Jung Lai,Kai-Cheng Hsu,Yun Yen,Tony Eight Lin.
Purine/Purine isoster based scaffolds as new derivatives of benzamide class of HDAC inhibitors
. European Journal of medicinal chemistry
.2020
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| 30. |
2020
Navdeep Kaur,Yao-Ching Fang,Hsueh-Yun Lee,Arshdeep Singh,Kunal Nepali,Mei-Hsiang Lin.
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment
. European Journal of medicinal chemistry
.2020
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| 31. |
2020
Ritu Ojha,Kunal Nepali,Chun-Han Chen,Kuo-Hsiang Chuang,Tung-Yun Wu,Tony Eight Lin.
Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo.
. European Journal of Medicinal Chemistry
.2020
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| 32. |
2020
Steering the antitumor drug discovery campaign towards structurally diverse indolines
. Bioorganic Chemistry
.2020
;(0)
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| 33. |
2020
Kuei-Ju Cheng,Chien-Ming Hsieh,Kunal Nepali,Jing-Ping Liou.
Ocular Disease Therapeutics: Design and Delivery of Drugs for Diseases of the Eye
. J Med Chem
.2020
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| 34. |
2020
sachin sharma,Arshdeep singh,sahil sharma,Ram Sharma,kunal nepali,Jing Ping Liou.
Tailored Quinolines Demonstrate Flexibility to Exert Antitumor Effects through Varied Mechanisms-A Medicinal Perspective
. Anticancer agents in medicinal chemistry
.2020
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| 35. |
2019
Nepali K,Lee HY,Liou JP.
Nitro-Group-Containing Drugs.
. J Med Chem
.2019
;(62):2851-2893
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| 36. |
2019
1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase
. European journal of medicinal chemistry
.2019
;(162):612-630
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| 37. |
2019
Kunal Nepali, Lin MH,Chao MW, Peng SJ, Hsu KC, Lin TE.
Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells
. Bioorganic paper
.2019
;(91):103119-103119
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| 38. |
2018
1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC.
. Eur J Med Chem.
.2018
;(150):667-677
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| 39. |
2018
(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo.
. J Med Chem
.2018
;(61):905-917
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| 40. |
2017
Idiopathic Pulmonary Fibrosis: Current Status, Recent Progress, and Emerging Targets
. J Med Chem
.2017
;(60):527-553
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| 41. |
2017
Manroopraj Kaur,Amandeep Kaur,Suhani Mankotia, Harbinder Singh, Arshdeep Singh,Jatinder Vir Singh.
Synthesis, screening and docking of fused pyrano[3,2-d]pyrimidine derivatives as xanthine oxidase inhibitor.
. European journal of medicinal chemistry
.2017
;(131):14-28
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| 42. |
2017
Ring-opened tetrahydro-γ-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms.
. Eur J Med Chem
.2017
;(127):115-127
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| 43. |
2016
Sahil Sharma,Jagjeet Singh,Ritu Ojha,Harbinder Singh,Manpreet Kaur,Kunal Nepali.
Design strategies, structure activity relationship and mechanistic insights for purines as kinase inhibitors
. European Journal of Medicinal Chemistry
.2016
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| 44. |
2016
Early investigational tubulin inhibitors as novel cancer therapeutics.
. Expert Opin Investig Drugs
.2016
;(25):917-936
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| 45. |
2016
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition.
. Org Biomol Chem.
.2016
;(14):716-723
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| 46. |
2015
Harpreet S. Virdi,Sahil Sharma,Samir Mehndiratta,P. M. S. Bedi,Kunal Nepali.
Design, synthesis and evaluation of 2, 4-diarylpyrano [3, 2-c] chromen-5 (4H)-one as a new class of non-purine xanthine oxidase inhibitors
. Journal of Enzyme Inhibition and Medicinal Chemistry
.2015
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