明智煥(Jihwan Myung) 副教授

Email
jihwan@tmu.edu.tw
現   職
心智意識與腦科學研究所 副教授

學經歷

學 歷

畢業學校與學位[修業時間]
Kyoto UniversityLife Sciences 博士
2008/04~2012/07
Pohang University of Science and TechnolPhysics 碩士
2003/03~2005/02
University of WashingtonPhisiology and Biophysics 碩士
2006/09~2007/12
Korea UniversityPhysics 學士
1999/09~2002/08

本校學術經歷

任職單位與職稱[起迄時間]
心智意識與腦科學研究所副教授
2019/08/01~
醫學人文研究所副教授
2018/08/20~2019/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
心智意識與腦科學研究博士學位學程副教授
2020/01/01 ~

其它經歷

任職單位與職稱[起迄時間]
雙和醫院醫學研究員
2018/03~2018/08
Einstein Foundation BerlinResearch Fellow
2017/04~2017/06
Okinawa Institute of Science and TechnologyVisiting Researcher
2016/11~2017/10
Wissenschaftskollegzu BerlinFellow
2016/09~2017/03
RIKEN Brain Science InstituteResearch Scientist
2013/04~2016/11
Hiroshima UniversityAssistant Professor
2012/10~2013/03
Osaka Bioscience InstitutePredoctoral Researcher
2006/04~2006/09
Korea UniversityPredoctoral Researcher
2005/03~2006/03

專長與研究領域

學門領域
心智科學腦影像研究
心智科學腦影像研究
生理
Physiology
腎臟
Renal Physiology & Nephrology
生物化學及分子生物
Biological Biochemistry and Molecular Biology
軟物質及生物物理-模擬
Soft Matter and Biophysics-Simulation
學術專長
生理
Physiology
神經內分泌學
神經內分泌學
醫學之生化及分子生物
Biochemistry and Molecular Biology - Medicine
Electrophysiology
Electrophysiology
Molecular Biology
Molecular Biology
Molecular Imaging
Molecular Imaging
Neuroscience
Neuroscience
失智症
Dementia
生物精神醫學
生物精神醫學
分子生物學
分子生物學
計算生物學
Computational Biology
軟物質及生物物理-實驗
Soft Matters and Biophysics-Experiment

論文著作

清冊下載


1. 2024 Sládek M,Houdek P,Myung J,Semenovykh K,Dočkal T,Sumová A. The circadian clock in the choroid plexus drives rhythms in multiple cellular processes under the control of the suprachiasmatic nucleus . Fluids and Barriers of the CNS .2024 ;(21)

2. 2024 Myung J,Silver R,Jones JR,Nakamura TJ,Ono D. Development of Circadian Clock Functions (II) . Frontiers in Neuroscience .2024 ;(18)

3. 2024 Myung J. Enhancing Bioluminescence Imaging of Cultured Tissue Explants Using Optical Telecompression . Sensors .2024 ;(24)

4. 2024 Le DC,Ngo MH T,Kuo YC,Chen SH,Lin CY,Pham QTT, Au HK, Myung J, Huang YH. Secretome from estrogen-responding human placenta-derived mesenchymal stem cells rescues ovarian function and circadian rhythm in mice with cyclophosphamide-induced primary ovarian insufficiency . Journal of Biomedical Science .2024 ;(31)

5. 2023 Myung J,Hong S,Schmal C,Vitet H,Wu MY. Weak Synchronization Can Alter Circadian Period Length: Implications for Aging and Disease Conditions . Frontiers in Neuroscience .2023 ;(17)

6. 2023 Truong VH,Myung J. LocoBox: modular hardware and open-source software for circadian entrainment and behavioral monitoring in home cages . Sensors .2023 ;(23)

7. 2022 Schmal C,Hong S,Tokuda IT,Myung J. Coupling in biological systems: Definitions, mechanisms, and implications . Frontiers in Network Physiology .2022 ;(2)

8. 2021 Chrobok L,Jeczmien-Lazur JS,Bubka M,Pradel K,Klekocinska A,Klich JD, Rahim AR, Myung J, Kepczynski M, Lewandowski MH. Daily orexinergic modulation of the rat superficial layers of the superior colliculus–implications for intrinsic clock activities in the visual system . bioRxiv .2021

9. 2021 Chrobok L,Pradel K,Janik ME,Sanetra AM,Bubka M,Myung J, Rahim AR, Klich JD, Jeczmien-Lazur JS, Palus-Chramiec K, Lewandowski MH. Intrinsic circadian timekeeping properties of the thalamic lateral geniculate nucleus . bioRxiv .2021

10. 2021 Myung J,Nakamura TJ,Jones J,Silver R,Ono D. Development of Circadian Clock Functions . Frontiers in Neuroscience .2021

11. 2021 Quintela T,Furtado A,Duarte AC,Gonçalves I,Myung J,Santos CRA. The Role of Circadian Rhythm in Choroid Plexus Functions . Progress in Neurobiology .2021

12. 2021 Chrobok L,Jeczmien-Lazur JS,Bubka M,Pradel K,Klekocinska A,Klich JD, Rahim AR, Myung J, Kepczynski M, Lewandowski MH. Daily coordination of orexinergic gating in the rat superior colliculus - implications for intrinsic clock activities in the visual system . FASEB Journal .2021 ;(35)

13. 2021 Chrobok L,Pradel K,Janik ME,Sanetra AM,Bubka M,Myung J, Rahim AR, Klich JD, Jeczmien-Lazur JS, Palus-Chramiec K, Lewandowski MH. Intrinsic circadian timekeeping properties of the thalamic lateral geniculate nucleus . Journal of Neuroscience Research .2021

14. 2021 Chrobok L,Belle MDC,Myung J. From fast oscillations to circadian rhythms: coupling at multiscale frequency bands in the rodent subcortical visual system . Frontiers in Physiology .2021 ;(12)

15. 2020 C Schmal,H Herzel,J Myung. Clocks in the Wild: Entrainment to Natural Light . Frontiers in Physiology .2020 ;(11)

16. 2020 Chrobok L,Northeast RC,Myung J,Cunningham PS,Petit C,Piggins HD. Timekeeping in the hindbrain: a multi-oscillatory circadian centre in the mouse dorsal vagal complex . Communications Biology .2020 ;(3)

17. 2019 Schmal C,Ono D,Myung J,Pett JP,Honma S,Honma KI, Herzel H, Tokuda IT. Weak coupling between intracellular feedback loops explains dissociation of clock gene dynamics . bioRxiv .2019

18. 2019 Myung J,Wu MY,Lee CY,Rahim AR,Truong VH,Wu D, Piggins HD, Wu MS. The Kidney Clock Contributes to Timekeeping by the Master Circadian Clock . International Journal of Molecular Sciences .2019 ;(20)

19. 2019 Schmal C,Ono D,Myung J,Pett JP,Honma S,Honma KI, Herzel H, Tokuda IT. Weak coupling between intracellular feedback loops explains dissociation of clock gene dynamics . PLOS Computational Biology .2019 ;(15)

20. 2018 Timothy Joseph Lane,Philip Tseng,Changwei Wu,Tzu-Yu Hsu,Jihwan Myung,Niall Duncan. 意識測量儀初登場 . 科學人 .2018 ;(193):38-42

21. 2018 Jihwan Myung,Christoph Schmal,Sungho Hong,Yoshiaki Tzukizawa,Pia Rose,Yong Zhang, Michael J. Holtzman, Erik De Schutter, Hanspeter Herzel, Grigory Bordyugov, Toru Takumi. The choroid plexus is an important circadian clock component . Nature Communications .2018 ;(9)

22. 2018 Jihwan Myung,Scott D. Pauls. Encoding seasonal information in a two-oscillator model of the multi- oscillator circadian clock . European Journal of Neuroscience .2018 ;(48):2718-2727

23. 2018 Jihwan Myung,Dean Wu,Valérie Simonneaux,Timothy Joseph Lane. Strong circadian rhythms in the choroid plexus: implications for sleep-independent brain metabolite clearance . Journal of Experimental Neuroscience .2018 ;(12):1-4

24. 2017 Christoph Schmal,Jihwan Myung,Hanspeter Herzel,Grigory Bordyugov. Moran’s I quantifies spatio-temporal pattern formation in neural imaging data . Bioinformatics .2017 ;(33):3072-3079

25. 2017 A Azzi,JA Evans,T Leise,Jihwan Myung,T Takumi,AJ Davidson, SA Brown. Network dynamics mediate circadian clock plasticity . Neuron .2017 ;(93):441-450

26. 2015 Jihwan Myung,S Hong,D DeWoskin,E De Schutter,DB Forger,T Takumi. GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time . Proceedings of the National Academy of Sciences of the United States of America .2015 ;(112):E3920-E3929

27. 2015 D DeWoskin,Jihwan Myung,MDC Belle,HD Piggins,T Takumi,DB Forger. Distinct roles for GABA across multiple timescales in mammalian circadian timekeeping . Proceedings of the National Academy of Sciences of the United States of America .2015 ;(112):E3911-E3919

28. 2015 Nobuhiro Nakai,Susumu Otsuka,Jihwan Myung,Toru Takumi. Autism spectrum disorder model mice: Focus on copy number variation and epigenetics . Science China Life Sciences .2015 ;(58):976-984

29. 2015 Alun TL Hughes,Cara L Croft,Rayna E Samuels,Jihwan Myung,Toru Takumi,Hugh D Piggins. Constant light enhances synchrony among circadian clock cells and promotes behavioral rhythms in VPAC2-signaling deficient mice . Scientific reports .2015 ;(5):14044

30. 2015 Tanoue S,Fujimoto K,Myung J,Hatanaka F,Kato Y,Takumi T. DEC2–E4BP4 heterodimer represses the transcriptional enhancer activity of the EE element in the Per2 promoter . Frontiers in Neurology .2015 ;(6):166

31. 2015 Schmal C,Myung J,Herzel H,Bordyugov G. A theoretical study on seasonality . Frontiers in Neurology .2015 ;(6):94

32. 2014 Goriki A,Hatanaka F,Myung J,Kim JK,Yoritaka T,Tanoue S, Abe T, Kiyonari H, Fujimoto K, Kato Y, Todo T, Matsubara A, Forger D, Takumi T. A novel protein, CHRONO, functions as a core component of the mammalian circadian clock . PLoS biology .2014 ;(12):e1001839

33. 2012 Myung J,Hong S,Hatanaka F,Nakajima Y,De Schutter E,Takumi T. Period coding of Bmal1 oscillators in the suprachiasmatic nucleus . Journal of Neuroscience .2012 ;(32):8900-8918

34. 2010 Hatanaka F,Matsubara C,Myung J,Yoritaka T,Kamimura N,Tsutsumi S, Kanai A, Suzuki Y, Sassone-Corsi P, Aburatani H, Sugano S, Takumi T. Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism . Molecular and Cellular Biology .2010 ;(30):5636-5648

35. 2005 Kim TD,Kim JS,Kim JH,Myung J,Chae HD,Woo KC, Jang SK, Koh DS, Kim KT. Rhythmic serotonin N-acetyltransferase mRNA degradation is essential for the maintenance of its circadian oscillation . Molecular and Cellular Biology .2005 ;(25):3232-3246

研究計畫

計畫名稱
113 脈絡叢中的晝夜節律分化與發育協調:聚焦於腦脊液信號傳遞與腦積水的病理機制
補助單位
國家科學及技術委員會

計畫名稱
112 早期發育中生物鐘的出現
補助單位
國家科學及技術委員會

計畫名稱
111 早產兒身體器官病變所造成的腦神經發展障礙與來自身體的發炎訊號改變了脈絡叢屏障及其調控的晝夜節律有關-早產兒脈絡叢上免疫與晝夜節律的互動關聯是一個聯結「身體與腦部」之重要集線器(3/3)
補助單位
國家科學及技術委員會

計畫名稱
110 晝夜節律對大腦液體屏障之調節
補助單位
科技部

計畫名稱
110 早產兒身體器官病變所造成的腦神經發展障礙與來自身體的發炎訊號改變了脈絡叢屏障及其調控的晝夜節律有關-早產兒脈絡叢上免疫與晝夜節律的互動關聯是一個聯結「身體與腦部」之重要集線器(2/3)
補助單位
科技部

計畫名稱
109 早產兒身體器官病變所造成的腦神經發展障礙與來自身體的發炎訊號改變了脈絡叢屏障及其調控的晝夜節律有關-早產兒脈絡叢上免疫與晝夜節律的互動關聯是一個聯結「身體與腦部」之重要集線器(1/3)
補助單位
科技部

計畫名稱
109 運用馬桶理論探討腦內代謝物清除:日夜週期對 β類澱粉蛋白質堆積的影響
補助單位
科技部

計畫名稱
108 一個有力的情緒操控者 - 時差(2/2)
補助單位
科技部

計畫名稱
107 新聘教師研究補助
補助單位
臺北醫學大學

計畫名稱
107 時差對於大腦上視神經交叉核的丙胺基丁酸神經元網路結構之研究(2/2)
補助單位
科技部

計畫名稱
107 一個有力的情緒操控者 - 時差(1/2)
補助單位
科技部

計畫名稱
106 時差對於大腦上視神經交叉核的丙胺基丁酸神經元網路結構之研究(1/2)
補助單位
科技部