趙需文(Chao, Hsu-Wen) 副教授

Email
chaohw3619@tmu.edu.tw
現   職
生理學科 副教授

學經歷

學 歷

畢業學校與學位[修業時間]
國防醫學院生科所 博士
2004/09~2010/04
清華大學生科所 碩士
1999/09~2001/06
高雄醫學院生物系 學士
1995/09~1999/06

本校學術經歷

任職單位與職稱[起迄時間]
生理學科副教授
2021/02/01~
生理學科助理教授
2016/12/05~2021/01/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
日本京都大學博士後研究員
2011/12~2015/06
中研院生醫所博士後研究員
2010/06~2011/11
中研院分生所學生助理
2006/09~2010/03
長庚大學研究助理
2003/09~2004/06

專長與研究領域

學門領域
學術專長
分子及細胞生物學
分子及細胞生物學

論文著作

清冊下載


1. 2024 Hongcong Zhao,Guohao Han,Zhou Jiang,Dengke Gao,Haisen Zhang,Luda Yang, Tiantian Ma, Lei Gao, Aihua Wang, Hsu-Wen Chao, Qian Li, Yaping Jin, Huatao Chen . Identification of BMAL1-Regulated circadian genes in mouse liver and their potential association with hepatocellular carcinoma: Gys2 and Upp2 as promising candidates . Biochemical and Biophysical Research Communications .2024

2. 2024 Yu-Wen Chao,Yen-Lurk Lee,Ching-San Tseng,Lily Ueh-Hsi Wang,Kuo-Chiang Hsia,Huatao Chen, Jean-Michel Fustin, Sayma Azeem, Tzu-Tung Chang, Chiung-Ya Chen, Fan-Che Kung, Yi-Ping Hsueh, Yi-Shuian Huang, Hsu-Wen Chao. Improved CaP-nanoparticles for Nucleic Acid and Protein Delivery to Neural Primary Cultures and Stem Cells . ACS NANO .2024

3. 2024 Wanghao Yang ,Mengdong Jin,Yiqun Wang,Hongcong Zhao,Xuerong Wang,Yiying Guo, Chao Li, Bonan Xiao, Haisen Zhang, Kiran Fouzia, Aihua Wang, Hsu-Wen Chao , Yaping Jin , Huatao Chen. NR1D1 activation alleviates inflammatory response through inhibition of IL-6 expression in bovine endometrial epithelial cells . International Journal of Biological Macromolecules .2024

4. 2023 Ching-San Tseng,Yu-Wen Chao,Yi-Hsiang Liu,Yi-Shuian Huang,Hsu-Wen Chao. Dysregulated proteostasis network in neuronal diseases . Frontiers in Cell and Developmental Biology .2023 ;(11)

5. 2022 Chia-Wen Lin,Dian E. Septyaningtrias,Hsu-Wen Chao,Mikiko Konda,Koji Atarashi, ,Kozue Takeshita, Kota Tamada, Jun Nomura, Yohei Sasagawa, Kaori Tanaka, Itoshi Nikaido, Kenya Honda, Thomas J. McHugh, Toru Takumi. A common epigenetic mechanism across different cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse mode . Molecular Psychiatry .2022

6. 2022 Chen-Shiou Wu,Wen-Hsin Lu,Mien-Chie Hung,Yi-Shuian Huang,Hsu-Wen Chao. From polyploidy to polyploidy reversal, the role in normal and disease states . Trends in Genetics .2022

7. 2021 Lin H,Huang YS,Fustin JM,Doi M,Chen H,Lai HH, Lin SH, Lee YL, King PC, Hou HS, Chen HW, Young PY, Chao HW. Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver . Nature Communications .2021

8. 2021 Xiao YY,Zhao L,Li WD,Wang X,Ma TT,Yang L, 「Gao L, Li I, Zhang M, Yang D, Zhang J, Jiang H, Zhao HG, Wang YQ, Chao HW, Wang AH, Jin YP, Chen H」. Circadian clock gene BMAL1 controls testosterone production by regulating steroidogenesis‐related gene transcription in goat Leydig cells . Journal of Cellular Physiology .2021

9. 2021 Lijia Zhao, ,Luda Yang, ,Jing Zhang, ,Yaoyao Xiao, ,Meina Wu,,Tiantian Ma, 「Xiaoyu Wang, Linlin Zhang, Haizhen Jiang, Hsu-Wen Chao, Aihua Wang, Yaping Jin, Huatao Chen」. Bmal1 promotes prostaglandin E2 synthesis by up-regulating Ptgs2 transcription in response to increasing estradiol levels in day 4 pregnant mice . American Journal of Physiology-Endocrinology and Metabolism .2021

10. 2021 Wen-Hsin Lu,Hsu-Wen Chao,Pei-Yi Lin,Shu-Hui Lin,Tzu-Hsien Liu,Hao-Wen Chen, Yi-Shuian Huang. CPEB3-dowregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice . Neuropsychopharmacology .2021

11. 2021 Luda Yang, ,Tiantian Ma, ,Lijia Zhao, ,Haizhen Jiang, ,Jing Zhang,Dongyao Liu, Linlin Zhang, Xiaoyu Wang, Tao Pan, Haisen Zhang, Aihua Wang, Hsu-Wen Chao, Yaping Jin, Huatao Chen. Circadian regulation of apolipoprotein gene expression affects testosterone production in mouse testis . Theriogenology .2021 ;(174):9-19

12. 2021 Luda Yang,Tiantian Ma,Lijia Zhao ,Haizhen Jiang,Jing Zhang,Dongyao Liu, Linlin Zhang, Xiaoyu Wang, Tao Pan, Haisen Zhang, Aihua Wang, Hsu-Wen Chao, Yaping Jin, Huatao Chen. Circadian regulation of apolipoprotein gene expression affects testosterone production in mouse testis . Theriogenology .2021 ;(179):9-19

13. 2020 Lai YT,Chao HW,Lai CY,Lin SH,Chang YJ,Huang YS. CPEB2-activated PDGFRα mRNA translation contributes to myofibroblast proliferation and pulmonary alveologenesis . Journal of Biomedical Science .2020

14. 2020 Huang YS,Lu KC,Chao HW,Chen A,Chao TK,Guo CY, Hsieh HY, Shih HM, Sytwu HK, Wu CC. The MTNR1A mRNA is stabilized by the cytoplasmic hnRNPL in renal tubular cells . Journal of cellular physiology .2020

15. 2019 Chao HW,Chao SW,Lin H,Ku HC,Cheng CF. Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease . International Journal of Molecular Sciences .2019 ;(20)

16. 2018 Liu HY,Chen CY,Hung YF,Lin HR,Chao HW,Shih PY, Chuang CN, Li WP, Huang TN, Hsueh YP. RNase A Promotes Proliferation of Neuronal Progenitor Cells via an ERK-Dependent Pathway . Frontiers in Molecular Neuroscience .2018 ;(11)

17. 2017 Tseng CS,Chao HW,Huang HS,Huang YS. Olfactory-Experience- and Developmental-Stage-Dependent Control of CPEB4 Regulates c-Fos mRNA Translation for Granule Cell Survival . Cell Reports .2017 ;(21):2264-2276

18. 2017 Chao HW,Doi M,Fustin JM,Chen H,Murase K,Maeda Y, Hayashi H, Tanaka R, Sugawa M, Mizukuchi N, Yamaguchi Y, Yasunaga J, Masao Matsuoka, Sakai M, Matsumoto M, Hamada S, Okamura H. Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signalling pathway . Nature Communications .2017 ;(8):1-14

19. 2016 Masao Doi,Iori Murai,Sumihiro Kunisue,Genzui Setsu,Naohiro Uchio,Rina Tanaka, Sakurako Kobayashi, Hiroyuki Shimatani, Hida Hayashi, Hsu-Wen Chao, Yuuki Nakagawa,. Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour . Nature Communication .2016

20. 2014 Wen-Hsuan Huang,Hsu-Wen Chao,Li-Yun Tsai,Ming-Hung Chung,Yi-Shuian Huang. Elevated activation of CaMKIIa in the CPEB3-knockout hippocampus impairs a specific form of NMDAR-dependent synaptic depotentiation. . Frontiers in Cellular Neuroscience .2014

21. 2013 Hsu-Wen Chao,Li-Yun Tsai,Yi-Ling Lu,Pei-Yi Lin,Wen-Hsuan Huang,Hsin-Jung Chou,. Deletion of CPEB3 Enhances Hippocampus-Dependent Memory via Increasing Expressions of PSD95 and NMDA Receptors. . Journal of Neuroscience .2013 ;(33):17008-17022

22. 2012 Hsu-Wen Chao,,Yen-Ting Lai,,Yi-Ling Lu,,Chi-long Lin,,Wei Mai,Yi-Shuian Huang. NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3. . Nucleic Acids Research .2012 ;(40):8484-8498

23. 2011 Hsiao-Fang Wang,,Yu-Tzu Shih,Chiung-Ya Chen,Hsu-Wen Chao,Ming-Jen Lee,Yi-Ping Hsueh. Valosin-containing protein and neurofibromin interact to regulate dendritic spine density. . Journal of Clinical Investigation .2011

24. 2008 Hsu-Wen Chao,Chen-Jei Hong,Tzyy-Nan Huang,Yi-Ling Lin,Yi-Ping Hsueh. SUMOylation of the MAGUK protein CASK regulates dendritic spinogenesis . Journal of Cell Biology .2008 ;(182):141-155

研究計畫

計畫名稱
112 Telekaryophagy,一種在肝臟和乳腺中新發現的全核消除程序:探索其在基因組穩定性和生理病理學中的作用(3/3)
補助單位
國家科學及技術委員會

計畫名稱
111 Telekaryophagy,一種在肝臟和乳腺中新發現的全核消除程序:探索其在基因組穩定性和生理病理學中的作用(2/3)
補助單位
國家科學及技術委員會

計畫名稱
110 Telekaryophagy,一種在肝臟和乳腺中新發現的全核消除程序:探索其在基因組穩定性和生理病理學中的作用(1/3)
補助單位
科技部

計畫名稱
109 探討生物時鐘所調控之新型態肝細胞分裂模式在肝臟生理功能及相關疾病中所扮演之角色(3/3)
補助單位
科技部

計畫名稱
108 探討生物時鐘所調控之新型態肝細胞分裂模式在肝臟生理功能及相關疾病中所扮演之角色(2/3)
補助單位
科技部

計畫名稱
107 探討生物時鐘所調控之新型態肝細胞分裂模式在肝臟生理功能及相關疾病中所扮演之角色(1/3)
補助單位
科技部

計畫名稱
106 The role of abscission failure in the formation of hepatocellular carcinoma.
補助單位
科技部

計畫名稱
106 發現新型態肝細胞分裂模式,探討其在肝臟生理代謝及相關疾病中所扮演之角色
補助單位
科技部

計畫名稱
105 新聘教師研究補助
補助單位
臺北醫學大學