陳信安(Chen, Hsin-An) 副教授

Email
d118101004@tmu.edu.tw
現   職
外科學科 副教授

學經歷

學 歷

畢業學校與學位[修業時間]
臺北醫學大學臨床醫學研究所 博士
臺灣大學醫學系 學士
1992/09~1999/06

本校學術經歷

任職單位與職稱[起迄時間]
外科學科副教授
2022/02/01~
外科學科助理教授
2015/11/10~2022/01/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
雙和醫院主治醫師
亞東紀念醫院主治醫師
2006/07/01~2011/02/28
臺大醫院住院醫師
2001/07/01~2006/06/30

專長與研究領域

學門領域
一般外科
學術專長

論文著作

清冊下載


1. 2023 Huang SW,Shen SC,Tsai KY,Kuo HH,Bernard Dallemagne, Howard C. Jen, Wei CH. Stepwise training program: A novel practice schedule for laparoscopic suturing . Heliyon .2023

2. 2023 Hsu Tung Wei,Su Yen Hao,Chen Hsin An,Liao Po Hsiang,Shen Shih Chiang,Tsai Kuei Yen,Wang Tzu Hsuan,Chen Alvin,Huang Chih Yang,Shibu Marthandam Asokan,Wang Wan Yu,Shen Shing Chuan,Hsu Tung Wei,Su Yen Hao,Chen Hsin An,Liao Po Hsiang,Shen Shih Chiang,Tsai Kuei Yen,Wang Tzu Hsuan,Chen Alvin,Huang Chih Yang,Shibu Marthandam Asokan,Wang Wan Yu,Shen Shing Chuan. Galectin-1-mediated MET/AXL signaling enhances sorafenib resistance in hepatocellular carcinoma by escaping ferroptosis . Aging .2023 ;(15):6503-6525

3. 2023 Tsai Kuei-Yen,Chang Yu-Jia,Huang Chien-Yu,Prince G M Shazzad Hossain,Chen Hsin-An,Makondi Precious Takondwa,Shen Ying-Rou,Wei Po-Li,Tsai Kuei-Yen,Chang Yu-Jia,Huang Chien-Yu,Prince G M Shazzad Hossain,Chen Hsin-An,Makondi Precious Takondwa,Shen Ying-Rou,Wei Po-Li. Novel heavily fucosylated glycans as a promising therapeutic target in colorectal cancer . Journal of Translational Medicine .2023 ;(21):505-505

4. 2023 Tsai Kuei-Yen,Wei Po-Li,Lee Cheng-Chin,Makondi Precious Takondwa,Chen Hsin-An,Chang Yao-Yuan,Liu Der-Zen,Huang Chien-Yu,Chang Yu-Jia,Tsai Kuei-Yen,Wei Po-Li,Lee Cheng-Chin,Makondi Precious Takondwa,Chen Hsin-An,Chang Yao-Yuan,Liu Der-Zen,Huang Chien-Yu,Chang Yu-Jia. 2,3,5,4'-Tetrahydroxystilbene (TG1), a Novel Compound Derived from 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside (THSG), Inhibits Colorectal Cancer Progression by Inducing Ferroptosis, Apoptosis, and Autophagy . Biomedicines .2023 ;(11)

5. 2023 Su Chih Ming,Hsu Tung Wei,Chen Hsin An,Wang Wan Yu,Huang Chih Yang,Hung Chih Chiang,Yeh Ming Hsin,Su Yen Hao,Huang Ming Te,Liao Po Hsiang,Su Chih Ming,Hsu Tung Wei,Chen Hsin An,Wang Wan Yu,Huang Chih Yang,Hung Chih Chiang,Yeh Ming Hsin,Su Yen Hao,Huang Ming Te,Liao Po Hsiang. Chaperone-mediated autophagy degrade Dicer to promote breast cancer metastasis . Journal of Cellular Physiology .2023 ;(238):829-841

6. 2023 Tsai Kuei-Yen,Wei Po-Li,Azarkan Mohamed,M'Rabet Nasiha,Makondi Precious Takondwa,Chen Hsin-An,Huang Chien-Yu,Chang Yu-Jia,Tsai Kuei-Yen,Wei Po-Li,Azarkan Mohamed,M'Rabet Nasiha,Makondi Precious Takondwa,Chen Hsin-An,Huang Chien-Yu,Chang Yu-Jia. Cytotoxic properties of unfractionated and fractionated bromelain alone or in combination with chemotherapeutic agents in colorectal cancer cells . PLoS ONE .2023 ;(18):e0285970-e0285970

7. 2023 Chen HA,Huang SW,Shen SC,Tsai KY,Kuo HH,Bernard Dallemagne h,i , Howard C. Jen j , Wei CH. Stepwise training program: A novel practice schedule for laparoscopic suturing . Heliyon .2023

8. 2022 Wei CH,Shen SC,Du YC,Tsai KY,Chen HA,Huang SW. Inter-rater and intra-rater reliability of the current assessment model and tools for laparoscopic suturing . Surgical Endoscopy .2022

9. 2022 Hsu TW,Chen HA,Liao PH,Su YH,Chiu CF,Huang CY,Lin YJ, Hung CC, Yeh MH, Sumg SY, Su CM. Dicer-mediated miR-200b expression contributes to cell migratory/invasive abilities and cancer stem cells properties of breast cancer cells . Aging .2022

10. 2021 Chen Hsin An,Li Chi Cheng,Lin Yu Jung,Wang Tso Fu,Chen Ming Cheng,Su Yen Hao,Yeh Yu Lan,Padma V. Vijaya,Liao Po Hsiang,Huang Chih Yang,Chen Hsin An,Li Chi Cheng,Lin Yu Jung,Wang Tso Fu,Chen Ming Cheng,Su Yen Hao,Yeh Yu Lan,Padma V. Vijaya,Liao Po Hsiang,Huang Chih Yang. Hsa-miR-107 regulates chemosensitivity and inhibits tumor growth in hepatocellular carcinoma cells . Aging .2021 ;(13):12046-12057

11. 2021 Park JM,Mau CZ,Chen YC,Su YH,Chen HA, Huang SY, Chang JS, Chiu CF. A case-control study in Taiwanese cohort and meta-analysis of serum ferritin in pancreatic cancer . scientific report .2021 ;(11)

12. 2021 Su CM,Hsu TW,Sung SY,Huang MT,Chen KC,Huang CY, Chiang CY, Su YH, Chen HA, Liao PH. AXL is crucial for E1A-enhanced therapeutic efficiency of EGFR tyrosine kinase inhibitors through NFI in breast cancer . Environmental toxicology .2021

13. 2021 Lai HY,Tsai KY,Chen HA. Routine intraoperative cholangiography during laparoscopic cholecystectomy: application of the 2016 WSES guidelines for predicting choledocholithiasis . Surgical Endoscope .2021

14. 2020 Su YH ,Hsu TW,Chen HA,Su CM,Huang MT,Chuang TH, Su JL, Hsieh SL, Chiu CF. ERK-mediated transcriptional activation of Dicer is involved in gemcitabine resistance of pancreatic cancer . Journal of cellular physiology .2020

15. 2020 Zhou JF,Su CM,Chen HA,Du SC,Li CW,Wu haoran, Tsai SH, Yeh YT. Cryptanshinone Inhibits the Glycolysis and Inhibits Cell Migration Through PKM2/β-Catenin Axis in Breast Cancer . OncoTargets and Therapy .2020

16. 2019 Li CL,Lin YK,Chen HA,Huang CY,Huang MT,Chang YJ. Smoking as an Independent Risk Factor for Hepatocellular Carcinoma Due to the α7-Nachr Modulating the JAK2/STAT3 Signaling Axis . Journal of clinical medicine .2019

17. 2019 Chen HA ,Chen CM,Guan SS,Chiang CK,Wu CT,Liu SH. The antifibrotic and anti-inflammatory effects of icariin on the kidney in a unilateral ureteral obstruction mouse model . Phytomedicine .2019

18. 2019 Shen SC,Wang W,Tam KW,Chen HA,Lin YK,Wang SY, Huang MT, Su YH. Validating Risk Prediction Models of Diabetes Remission After Sleeve Gastrectomy . Obesity Surgery .2019 ;(29):221-229

19. 2019 Wu JM,Kuo TC,Chen HA,Wu CH,Lai SR,Yang CY, Hsu SY, Ho TW, Liao WC, Tien YW. Randomized trial of oral versus enteral feeding for patients with postoperative pancreatic fistula after pancreatoduodenectomy . The british journal of surgery .2019 ;(106):190-198

20. 2018 Tsai KY,Chen HA,Wang WY,Huang MT. Risk Factors Analysis of Postoperative Pleural Effusion after Liver Resection . Digestive Surgery .2018

21. 2018 Tsai KY,Chen HA,Wang WY,Huang MT. Long-term and short-term surgical outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma: might laparoscopic approach be better in early HCC? . Surgical endoscopy .2018

22. 2018 Chang HL,Chen HA,Bamodu OA,Lee KF,Tzeng YM,Lee WH, Tsai JT. Ovatodiolide suppresses yes-associated protein 1-modulated cancer stem cell phenotypes in highly malignant hepatocellular carcinoma and sensitizes cancer cells to chemotherapy in vitro . Toxicology in Vitro .2018 ;(51):74-82

23. 2018 Chen L,Wu YH,Lee LH,Chen HA,Loh EW,Tam KW. Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma with Clinically Uninvolved Central Neck Lymph Nodes: A Systematic Review and Meta-analysis. . World Journal of Surgery .2018 ;(42):2846-2857

24. 2017 Kiu KT,Chn HL,Hung MT,Sung SW,Liaw YP,Chang CC, Wang YH, Chen HA. Outcome Analysis of Patients with Gallstone Disease Receiving Cholecystectomy: A Population-Based Cohort Study . Digestion .2017 ;(95):132-139

25. 2017 Hsieh CL,Liu CM,Chen HA,Yang ST,Katsumi Shigemura,Koichi Kitagawa, Fukashi Yamamichi, Masato Fujisawa, Liu YR, lee WH, Chen KC, Shen CN, Lin CC, leland W.K. Chung, Sung SY. Reactive oxygen species-mediated switching expression of MMP-3 in stromal fibroblasts and cancer cells during prostate cancer progression. . Scientific Reports .2017 ;(7)

26. 2016 Chang TY, Chen HA,Chiu CF,Chang YW,Kuo TC,Wang W,Hung MC, Su JL. Dicer Elicits Paclitaxel Chemosensitization and . Cancer research .2016 ;(76):3916-3928

27. 2016 Chen HA,Kuo TC,Tseng CF,Ma JT,Yang ST,Yen CJ, Yang CY, Sung SY, Su JL. Angiopoietin-like protein 1 antagonizes MET receptor activity to repress sorafenib resistance and cancer stemness in hepatocellular carcinoma . Hepatology .2016 ;(64):1637-1651

28. 2015 Su CM,Wang MY,Hong CC,Chen HA,Su YH,Wu CH, Huang MT, Chang YW, Jiang SS, Sung SY, Chang JY, Chen LT, Chen PS, Su JL. miR-520h is crucial for DAPK2 regulation and breast cancer progression. . Oncotarget .2015

29. 2015 Chen HA,Chang YW,Tseng CF,Chiu CF,Hong CC,Wang MY, Hsiao Michael, Ma JT, Chen CH, Jiang SS, Wu CH, Hung MC, Huang MT, Su JL. E1A-Mediated Inhibition of HSPA5 Suppresses Cell Migration . Annals of surgical oncology .2015 ;(22):889-898

30. 2014 Chang YJ,Li LT,Chen HA,Hung CS,Wei PL. Silencing survivin activates autophagy as an alternative survival pathway in HCC cells . Tumour Biology .2014 ;(35):9957-66

31. 2014 Huynh TT,Rao YK,Lee WH,Chen HA,Le TD,Tzeng DT, Wang LS, Wu AT, Lin YF, Tzeng YM, Yeh CT. Destruxin B inhibits hepatocellular carcinoma cell growth through modulation of the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition . Toxicol in vitro .2014 ;(28):522-61

32. 2014 Chen JC,Su YH,Chiu CF,Chang YW,Yu YH,Tseng CF, Chen HA, Su JL. Suppression of Dicer increases sensitivity to gefitinib in human lung cancer cells. . Annals of surgical oncology .2014 ;(21):S555-63

33. 2014 Chang YW,Chen HA,Tseng CF,Hong CC,Ma JT,Hung MC, Wu CH, Huang MT, Su JL. De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells . Oncotarget .2014 ;(5):10558-10570

34. 2014 Chen HA,SU CM,Hsieh HY,Tung CL,Hsu CD,Wang YH, Shen CH. Clinical Significance of Survivin Expression in Patients with . Disease Markers .2014

35. 2014 Huang ZM,Chen HA,Chiang YT,Shen CH,Yung MC,Juang GD. Association of polymorphisms in iNOS and NQO1 with bladder cancer risk in cigarette smokers . Journal of Chinese Medical association .2014 ;(77):83-88

36. 2014 Chang YW,Su CM,Su YH,HO YS,Lai HH,Chen HA, Kuo ML, Hung WC, Chen YW, Wu CH, Chen PS, Su JL. Novel peptides suppress VEGFR-3 activity and antagonize VEGFR-3-mediated oncogenic effects . Oncotarget .2014 ;(5):3823-3835

37. 2014 Su CM,Chen MC,Lin IC,Chen HA,Huang MT,Wu CH, Shen KH,Wang YH. Association between the SULT1A1 Arg213His polymorphism and the risk of bladder cancer: a meta-analysis . Tumour Biology .2014 ;(35):7147-53

38. 2013 Yu YH,Chen HA,Chen PS,Cheng YJ,Hsu WH,Chang YW, Chen YH. Jan YH, Hsiao Michael, Chang TY, Liu YH, Jeng YM, Wu CH, Huang MT, Su YH, Hung MC. MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by reseveratrol . Oncogene .2013 ;(32):431-443

39. 2013 Wu TY,Chen HA,Li FY,Wu CM,Hsieh FC,Tzen JT, Hsieh SK, Ko JL, Jinn TR. High-level expression, purification and production of the fungal immunomodulatory protein-gts in baculovirus-infected insect larva . Appl Biochem biotechnol .2013 ;(169):976-89

40. 2012 Tai CJ,Hung SS,Kuo LJ,Wei PL,Lu HH,Chen HA, Liu TZ, Liu JJ, Liu DZ, Ho YS, Wu CH, Chang YJ. Survivin-Mediated Cancer Cell Migration Through GRP78 and Epithelial-Mesenchymal Transition (EMT) Marker Expression in Mahlavu Cells . Annals of surgical oncology .2012 ;(19):336-343

41. 2012 Tsai KY,Chen HA. Mature Cystic Teratoma of the Greater Omentum Diagnosed as Intra-abdominal Tumor . Journal of Experimental & Clinical Medicine .2012 ;(4):298-299

研究計畫

計畫名稱
108 然物雷公藤內酯應用於增強化療藥物蕾莎瓦治療肝癌的潛能研究
補助單位
科技部

計畫名稱
107 Long noncoding RNA在Dicer調控之micro-RNA重新編程的角色與sorafenib在肝癌中產生抗藥性的研究探討
補助單位
科技部

計畫名稱
105 探討Dicer在肝癌細胞對sorafenib抗藥性的影響及其調控機制
補助單位

計畫名稱
104 研究E1A基因治療的抗腫瘤活性:專注於微核醣核酸的生合成及生理功能
補助單位
科技部