郭漢彬(Kuo, Han-Pin) 教授

Email
q8828@tmu.edu.tw
現   職
內科學科 教授

學經歷

學 歷

畢業學校與學位[修業時間]
英國倫敦大學National Heart & Lung Institute 博士
1989/02~1991/10
台北醫學院醫學系 學士
1975/09~1982/06

本校學術經歷

任職單位與職稱[起迄時間]
內科學科教授
2018/04/01~

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
臨床醫學研究所教授
2019/08/01 ~
人工智慧醫療碩士在職專班教授
2019/08/01 ~
人工智慧醫療碩士在職專班籌備處教授
2019/05/01 ~ 2019/07/31
(舊)細胞治療與再生醫學國際博士學位學程籌備處教授
2018/08/01 ~
胸腔醫學研究中心主任
2018/08/01 ~ 2024/02/29
醫學院院長
2018/04/01 ~ 2024/03/31

其它經歷

任職單位與職稱[起迄時間]
長庚大學醫學院醫學系教授
2017/08~2018/03
長庚紀念醫院內科部部長
2011/07~2018/03
長庚紀念醫院胸腔內科系系主任
2003/07~2010/06
長庚大學醫學院醫學系教授
2001/08~2012/02
長庚紀念醫院胸腔內科系科主任
1995/07~2003/06
長庚大學醫學院醫學系副教授
1993/08~2001/07

專長與研究領域

學門領域
學術專長
氣喘
氣喘

論文著作

清冊下載


1. 2024 Weng CM,Wu WC,Lee MJ,Chen MC,Chou CL,Lin CY, Chung KF, Kuo HP. Influence of Staphylococcal enterotoxin-specific IgE sensitization on therapeutic efficacy of omalizumab therapy in severe asthma . Respirology .2024

2. 2023 Weng Chih Ming,Lee Meng Jung,Chao Wei,Lin Yuh Rong,Chou Chun Ju,Chen Mei Chuan,Chou Chun Liang,Tsai I. Lin,Lin Chien Huang,Fan Chung Kian,Kuo Han Pin. Airway epithelium IgE-FcεRI cross-link induces epithelial barrier disruption in severe T2-high asthma . Mucosal Immunology .2023 ;(16):685-698

3. 2023 Chang Jer Hwa,Lee Yueh Lun,Chang Li Te,Chang Ta Yuan,Hsiao Ta Chih,Chung Kian Fan,Ho Kin Fai,Kuo Han Pin,Lee Kang Yun,Chuang Kai Jen,Chuang Hsiao Chi. Climate change, air quality, and respiratory health: a focus on particle deposition in the lungs . Annals of Medicine .2023 ;(55)

4. 2023 Hua Hung-Sheng,Wen Heng-Ching,Lee Hong-Sheng,Weng Chih-Ming,Fara Silvia Yuliani,Kuo Han-Pin, Chen Bing-Chang, Lin Chien-Huang. Endothelin-1 induces connective tissue growth factor expression in human lung fibroblasts by disrupting HDAC2/Sin3A/MeCP2 corepressor complex . J Biomed Sci .2023

5. 2023 Hsiao Ta Chih,Han Chia Li,Yang Tzu Ting,Lee Yueh Lun,Shen Yu Fang,Jheng Yu Teng,Lee Chii Hong,Chang Jer Hwa,Chung Kian Fan,Kuo Han Pin,Chuang Hsiao Chi,Hsiao Ta Chih,Han Chia Li,Yang Tzu Ting,Lee Yueh Lun,Shen Yu Fang,Jheng Yu Teng,Lee Chii Hong,Chang Jer Hwa,Chung Kian Fan,Kuo Han Pin,Chuang Hsiao Chi. Importance of surface charge of soot nanoparticles in determining inhalation toxicity in mice . Environmental Science and Pollution Research .2023

6. 2023 Yang FM,Hu MC,Weng CM,Chuang HC,Lan YT,Su BH,Heo KS,Kuo HP. Loss of PP4 contributes to diesel exhaust particles-induced epithelial barrier integrity disruption and alarmins release . Allergy .2023

7. 2023 Tran Huan Minh,Tsai Feng Jen,Lee Yueh Lun,Chang Jer Hwa,Chang Li Te,Chang Ta Yuan,Chung Kian Fan,Kuo Han Pin,Lee Kang Yun,Chuang Kai Jen,Chuang Hsiao Chi,Tran Huan Minh,Tsai Feng Jen,Lee Yueh Lun,Chang Jer Hwa,Chang Li Te,Chang Ta Yuan,Chung Kian Fan,Kuo Han Pin,Lee Kang Yun,Chuang Kai Jen,Chuang Hsiao Chi. The impact of air pollution on respiratory diseases in an era of climate change: A review of the current evidence . Science of the Total Environment .2023 ;(898)

8. 2022 Lee MJ,Weng CM,Chao W,Fang YF,Chung FT,Lin CH,Kuo HP. Platelet activation in high D-dimer plasma plays a role in acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in patients with mutant lung adenocarcinoma . Front Oncol .2022 ;(12)

9. 2022 Hsiao TC,Cheng PC,Chi KH,Wang HY,Pan SY,Kao C, Lee YL, Kuo HP, Chung KF, Chuang HC. Interactions of chemical components in ambient PM2.5 with influenza viruses . J Hazard Mater .2022 ;(423):127243-127243

10. 2022 Chang JH,Lee YL,Laiman V,Han CL,Jheng YT,Lee KY, Yeh CT, Kuo HP, Chung KF, Heriyanto DS, Hsiao TC, Wu SM, Ho SC, Chuang KJ, Chuang HC. Air pollution-regulated E-cadherin mediates contact inhibition of proliferation via the hippo signaling pathways in emphysema . Chem Biol Interact .2022 ;(35):109763-10763

11. 2022 Wang Chun Hua,Lo Chun Yu,Huang Hung Yu,Wang Tsai Yu,Weng Chih Ming,Chen Chih Jung,Huang Yu Chen,Chung Fu Tsai,Lin Chang Wei,Chung Kian Fan,Kuo Han Pin,Wang Chun Hua,Lo Chun Yu,Huang Hung Yu,Wang Tsai Yu,Weng Chih Ming,Chen Chih Jung,Huang Yu Chen,Chung Fu Tsai,Lin Chang Wei,Chung Kian Fan,Kuo Han Pin. Oxygen Desaturation Is Associated With Fibrocyte Activation via Epidermal Growth Factor Receptor/Hypoxia-Inducible Factor-1α Axis in Chronic Obstructive Pulmonary Disease . Frontiers in Immunology .2022 ;(13)

12. 2022 Chen Mei Chuan,Lai Kevin Shu Leung,Chien Ko Ling,Teng Sing Teck,Lin Yuh Rong,Chao Wei,Lee Meng Jung,Wei Po Li,Huang Yen Hua,Kuo Han Pin,Weng Chih Ming,Chou Chun Liang,Chen Mei Chuan,Lai Kevin Shu Leung,Chien Ko Ling,Teng Sing Teck,Lin Yuh Rong,Chao Wei,Lee Meng Jung,Wei Po Li,Huang Yen Hua,Kuo Han Pin,Weng Chih Ming,Chou Chun Liang. pcMSC Modulates Immune Dysregulation in Patients With COVID-19-Induced Refractory Acute Lung Injury . Frontiers in Immunology .2022 ;(13)

13. 2022 Tran Huan Minh,Chen Tzu Tao,Lu Yueh Hsun,Tsai Feng Jen,Chen Kuan Yuan,Ho Shu Chuan,Wu Chih Da,Wu Sheng Ming,Lee Yueh Lun,Chung Kian Fan,Kuo Han Pin,Lee Kang Yun,Chuang Hsiao Chi,Tran Huan Minh,Chen Tzu Tao,Lu Yueh Hsun,Tsai Feng Jen,Chen Kuan Yuan,Ho Shu Chuan,Wu Chih Da,Wu Sheng Ming,Lee Yueh Lun,Chung Kian Fan,Kuo Han Pin,Lee Kang Yun,Chuang Hsiao Chi. Climate-mediated air pollution associated with COPD severity . Science of the Total Environment .2022 ;(843)

14. 2021 Chen YC,Kuo HP,Hsia SM,Wu HT,Pan WH,Lee YL. Life course body mass index through childhood and young adulthood and risks of asthma and pulmonary function impairment . Pediatr Pulmonol .2021 ;(56):849-857

15. 2021 Lee SW,Huang YC,Lin CY,Huang HY,Liu CW,Hsieh MT,Lee CL,Chung WY,Chung KF,Wang CH,Kuo HP. Impact of Annual Exposure to Polycyclic Aromatic Hydrocarbons on Acute Exacerbation Frequency in Asthmatic Patients . J Asthma Allergy .2021 ;(14):81-90

16. 2021 Chen JY,Cheng WH,Lee KY,Kuo HP,Chung KF,Chen CL, Chen BC,Lin CH. Abnormal ADAM17 expression causes airway fibrosis in chronic obstructive asthma . Biomed Pharmacother .2021 ;(140):111701-111701

17. 2021 Chen XY,Feng PH,Han CL,Jheng YT,Wu CD,Chou HC,Chen YY,Wu SM,Lee KY,Kuo Han Pin,Chung Kian Fan,Hsiao Ta Chih,Chen Kuan Yuan,Ho Shu Chuan,Chang Ta Yuan,Chuang Hsiao Chi,Chen Xiao Yue,Feng Po Hao,Han Chia Li,Jheng Yu Teng,Wu Chih Da,Chou Hsiu Chu,Chen Yi Ying,Wu Sheng Ming,Lee Kang Yun,Kuo Han Pin,Chung KianF,Hsiao TC,Chen KY,Ho SC,Chang TY,Chuang HC. Alveolar epithelial inter-alpha-trypsin inhibitor heavy chain 4 deficiency associated with senescence-regulated apoptosis by air pollution . Environmental Pollution .2021 ;(278)

18. 2021 Putri DU,Wang CH,Tseng PC,Lee WS,Chen FL,Kuo HP,Lee CH,Lin CF. Profiles of peripheral immune cells of uncomplicated covid-19 cases with distinct viral rna shedding periods . Viruses .2021 ;(13)

19. 2021 Wang CH,Weng CM,Huang TT,Lee MJ,Lo CY,Chen MC,Chou CL,Kuo HP. Anti-IgE therapy inhibits chemotaxis, proliferation and transformation of circulating fibrocytes in patients with severe allergic asthma . Respirology .2021 ;(26):842-850

20. 2021 Tung NT,Ho SC,Lu YH,Chen TT,Lee KY,Chen KY,Wu CD,Chung KF,Kuo HP,Thao H,Dung HB,Thuy T,Wu SM,Kou HY,Lee YL,Chuang HC. Association Between Air Pollution and Lung Lobar Emphysema in COPD . Frontiers in medicine .2021 ;(8):705792-705792

21. 2021 Tung NT,Ho SC,Lu YH,Chen TT,Lee KY,Chen KY,Wu CD,Chung KF,Kuo HP,Thao H,Dung HB,Thuy T,Wu SM,Kou HY,Lee YL,Chuang HC. Higher alveolar deposition of particulate matter in emphysematous lobes of COPD . ERJ Open Res .2021 ;(7):00324-2021

22. 2021 Wang YH,Huang SY,Kuo HP,Fan HY,Moreira A,Papamichael MM,Chen YC. N-3 fatty acid supplementation in asthma management: A systematic review and meta-analysis . Allergy .2021 ;(76):3042-3046

23. 2021 Huang L,Wang ST,Kuo HP,Delclaux C,Jensen ME,Wood LG, Costa D, Nowakowski D, Wronka I, Oliv eira PD, Chen YC, Chen YC, Lee YL. Effects of obesity on pulmonary function considering the transition from obstructive to restrictive pattern from childhood to young adulthood . Obes Rev .2021 ;(22):e13327-e13327

24. 2020 Lo YL,Wu HT,Lin YT,Kuo HP,Lin TY. Hypoventilation Patterns During Bronchoscopic Sedation and Their Clinical Relevance Based on Capnographic and Respiratory Impedance Analysis . Journal of Clinical Monitoring and Computing .2020 ;(34):171-179

25. 2020 Chuang Hsiao Chi,Chen Yi Ying,Hsiao Ta Chih,Chou Hsiu Chu,Kuo Han Pin,Feng Po Hao,Ho Shu Chuan,Chen Jen Kun,Chuang Kai Jen,Lee Kang Yun,Chuang Hsiao Chi,Chen Yi Ying,Hsiao Ta Chih,Chou Hsiu Chu,Kuo Han Pin,Feng Po Hao,Ho Shu Chuan,Chen Jen Kun,Chuang Kai Jen,Lee Kang Yun. Alteration in angiotensin-converting enzyme 2 by pm1 during the development of emphysema in rats . ERJ Open Research .2020 ;(6):1-8

26. 2020 Lin CY,Huang YC,Huang HY,Chung FT,Lo YL,Lin SM,Wang CH,Kou HP. Effectiveness of Low-Dose Itraconazole in Fungal-Associated Severe Asthma: A Retrospective Study . J Asthma Allergy .2020 ;(13):453-461

27. 2019 Huang CC,Kuo HP,Lin YE,Chen SC. Effects of a Web-based Health Education Program on Quality of Life and Symptom Distress of Initially Diagnosed Advanced Non-Small Cell Lung Cancer Patients: A Randomized Controlled Trial . Journal of Cancer Education .2019 ;(34):1-9

28. 2019 Chen TR,Hu WY,Chiu TY,Kuo HP. Differences between COPD patients and their families regarding willingness toward life-sustaining treatments . Journal of the Formosan Medical Association .2019 ;(118):414-419

29. 2019 Huang YC,Weng CM,Lee MJ,Lin SM,Wang CH,Kuo HP. Endotypes of severe allergic asthma patients who clinically benefit from anti‐IgE therapy . Clinical Experimental Allergy .2019 ;(49):44-53

30. 2018 Weng CM ,Wang CH,Lee MJ,He JR,Huang HY,Chao MW,Chung KF,Kuo HP. Aryl hydrocarbon receptor activation by diesel exhaust particles mediates epithelium-derived cytokines expression in severe allergic asthma . Allergy: European Journal of Allergy and Clinical Immunology .2018 ;(73):2192-2204

31. 2018 Huang YC,Weng CM,Lee MJ,Lin SM,Wang CH,Kuo HP. Endotypes of severe allergic asthma patients who clinically benefit from anti-IgE therapy . Clinical and Experimental Allergy .2018 ;(49):44-53

32. 2018 Kim WJ,Gupta V,Nishimura M,Makita H,Idolor L,Roa C,Loh LC,Ong CK,Wang JS,Boonsawat W,Gunasekera KD,Madegedara D,Kuo HP,Wang CH,Wang C,Yang T,Lin YX,Ko FWS,Hui DSC,Lan LTT,Vu QTT,Bhome AB,Ng A,Seo JB,Lee BY,Lee JS,Oh YM,Lee SD. Identification of chronic obstructive pulmonary disease subgroups in 13 Asian cities . International Journal of Tuberculosis and Lung Disease .2018 ;(22):820-826

33. 2018 Chen TR,Hu WY,Chiu TY,Kuo HP. Differences between COPD patients and their families regarding willingness toward life-sustaining treatments . Journal of the Formosan Medical Association .2018 ;(118):414-419

34. 2018 Lee PC,Fang YF,Hirohito Y,Wang WJ,Chen TC,Hong X,Ke B,Xia W,Wei Y,Zha Z,Wang Y,Kuo HP,Wang CW,Tu CY,Chen CH,Huang WC,Chiang SF,Nie L,Hou J,Chen CT,Huo L,Yang WH,Deng R,Katsuya N,Hsu YH,Chang SS,Chiu TJ,Tang J,Zhang R,Wang L,Fang B,Chen T,Wong KK,Hsu JL,Hung MC. Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer . Cancer Cell .2018 ;(34):954-969

35. 2018 Weng CM,Lee MJ,He JR,Chao MW,Wang CH,Kuo HP. Diesel exhaust particles up-regulate interleukin-17A expression via ROS/NF-κB in airway epithelium . Biochemical Pharmacology .2018 ;(151):1-8

36. 2018 Lo CY,Huang HY,He JR,Huang TT,Heh CC,Sheng TF,Chung KF,Kuo HP,Wang CH. Increased matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 ratio in smokers with airway hyperresponsiveness and accelerated lung function decline . International Journal of COPD .2018

37. 2017 Wang TY,Lo YL,Lin SM,Huang CD,Chung FT,Lin HC,Wang CH,Kuo HP. Obstructive sleep apnoea accelerates FEV1 decline in asthmatic patients . BMC Pulmonary Medicine .2017 ;(17):55-55

38. 2017 Huang CD,Liao KC,Chung FT,Tseng HM,Fang JT,Lii SC,Kuo HP,Yeh SJ,Lee ST. Different perceptions of narrative medicine between Western and Chinese medicine students . BMC Medical Education .2017 ;(17):85

39. 2017 Lan Ying Wei ,Theng Si Min ,Huang Tsung Teng ,Choo Kong Bung ,Chen Chuan Mu ,Kuo HP, Chong KY. Oncostatin M-preconditioned mesenchymal stem cells alleviate bleomycin-induced pulmonary fibrosis through paracrine effects of the hepatocyte growth factor . Stem cells translational medicine .2017 ;(6):1006-1017

40. 2017 Lee TJ,Fu CH,Wang CH,Huang CC,Huang CC,Chang PH,Chen YW,Wu CC,Wu CL,Kuo HP. Impact of chronic rhinosinusitis on severe asthma patients . PLoS One .2017 ;(12):e0171047

41. 2017 Wang CH,Chou PC,Chung FT,Lin HC,Huang KH,Kuo HP. Heat shock protein70 is implicated in modulating NF-κ B activation in alveolar macrophages of patients with active pulmonary tuberculosis . Scientific Reports .2017 ;(7):1214

42. 2017 Zhang Z,Hong Y,Smischney NJ,Kuo HP,Tsirigotis P,Rello J,Kuan WS,Jung C,Robba C,Taccone FS,Leone M,Spapen H,Grimaldi D,Van Poucke S,Simpson SQ, Honore PM14, Hofer S, Caironi P. Early management of sepsis with emphasis on early goal directed therapy: AME evidence series 002 . Journal of Thoracic Disease .2017 ;(9):392-405

43. 2017 Huang CC,Kuo HP,Lin YE,Chen SC. Effects of a Web-based Health Education Program on Quality of Life and Symptom Distress of Initially Diagnosed Advanced Non-Small Cell Lung Cancer Patients: A Randomized Controlled Trial . Journal of Cancer Education .2017 ;(34):1-9

44. 2017 Lin TY,Fang YF,Huang SH,Wang TY,Kuo CH,Wu HT,Kuo HP,Lo YL. Capnography monitoring the hypoventilation during the induction of bronchoscopic sedation: A randomized controlled trial . Scientific Reports .2017 ;(7):8685-8685

45. 2017 Lo CY,Michaeloudes CC,Bhavsar PK,Huang CD,Chang PJ, Wang CH,Kuo HP,Chung KF. Reduced suppressive effect of β2-adrenoceptor agonist on fibrocyte function in severe asthma . Respiratory Research .2017 ;(18):194-194

46. 2016 Huang Hung Yu ,Chou Pai Chien ,Joa Wen Ching ,Chen Li Fei ,Sheng Te Fang ,Lin HC, Yang LY, Pan YB, Chung FT, Wang CH, Kuo HP. Pulmonary rehabilitation coupled with negative pressure ventilation decreases decline in lung function, hospitalizations, and medical cost in COPD: A 5-year study . Medicine(Baltimore) .2016 ;(95):e5119-e5119

47. 2016 Hsieh Chung Hsing ,Lin Ting Yu ,Wang Tsai Yu ,Kuo Chih Hsi ,Lin Shu Min ,Kuo HP, Lo YL. The safety and efficacy of alfentanil-based induction in bronchoscopy sedation: A randomized, double-blind, controlled trial . Medicine; analytical reviews of general medicine, neurology, psychiatry, dermatology, and pediatries .2016 ;(95):e5101-e5101

48. 2016 Chen Hao Cheng ,Huang Chien Da ,Chang Erin ,Kuo Han Pin . Efficacy of omalizumab (Xolair{\circledR) in patients with moderate to severe predominately chronic oral steroid dependent asthma in Taiwan: A retrospective, population-based database cohort study . BMC Pulmonary Medicine .2016 ;(16):3-3

49. 2016 Huang Shu Yi ,Chou Pai Chien ,Wang Tsai Yu ,Lo Yu Lun ,Joa Wen Ching ,Chen LF, Sheng TF, Chung KF, Wang CH, Kuo HP. Exercise-Induced Changes in Exhaled NO Differentiates Asthma with or Without Fixed Airway Obstruction from COPD with Dynamic Hyperinflation . Medicine (Baltimore) .2016 ;(95):e3400-e3400

50. 2016 Ho Shu-Chuan ,Wang Jiun Yi ,Kuo Han Pin ,Huang Chien Da ,Lee Kang-Yun ,Chuang HC, Feng PH, Chen TT, Hsu MF. Mid-arm and calf circumferences are stronger mortality predictors than body mass index for patients with chronic obstructive pulmonary disease . Int J Chron Obstruct Pulmon Dis. .2016 ;(11):2075-2080

51. 2015 Kuo Scott Chih Hsi ,Lo Yu Lun ,Chou Chun Liang ,Chung Fu Tsai ,Lin Shu Min ,Liu CY, Kuo HP. Bronchoscopic debulking for endobronchial malignancy: Predictors of recanalization and recurrence . Thoracic Cancer .2015 ;(6):722-730

52. 2015 Chung Fu Tsai ,Ho Ming Yun ,Fang Yueh Fu ,Hshieh Meng Heng ,Wang Tsai Yu , Kuo CH, Chen HC, Wang CH, Lin SM, Yu CT, Lin HC, Kuo HP. The Impact of Sequence of Chemotherapy and EGFR-TKI Treatment on Different EGFR Mutation Lung Adenocarcinoma . BioMed Research International .2015 ;(2015):948267-948267

53. 2015 Cheng Wei Tso ,Chen Huan Wen ,Su I. Hao ,Fang Ji Tseng ,Kuo Han Pin ,Huang CD. Vocal cord dysfunction diagnosed by four-dimensional dynamic volume computed tomography in patients with difficult-to-treat asthma: A case series . Journal of the Formosan Medical Association .2015 ;(114):1285-1290

54. 2015 Lan YW,Choo KB,Chen CM, Hung TH, Chen YB,Hsieh CH, Kuo HP, Chong KY. Hypoxia-preconditioned mesenchymal stem cells attenuate bleomycin-induced pulmonary fibrosis . Stem Cell Research and Therapy .2015 ;(6):97-97

55. 2015 Ho SC,Hsu MF,Kuo HP,Wang JY,Chen LF,Lee KY, Chuang HC. The relationship between anthropometric indicators and walking distance in patients with chronic obstructive pulmonary disease . International Journal of COPD .2015 ;(10):1857-1862

56. 2015 Liu WT, Kuo HP,Liao TH,Chiang LL,Chen LF,Hsu MF,Chuang HC, Lee KY, Huang CD, Ho SC. Low bone mineral density in COPD patients with osteoporosis is related to low daily physical activity and high COPD assessment test scores . International Journal of COPD .2015 ;(10):1737-1744

57. 2015 Juvelekian G,El-Sorougi W,Pothirat C,Yunus F,De Guia T,Kuo HP, Basu Patnaik S, Pilipovic V. A real-world evaluation of indacaterol and other bronchodilators in COPD: the INFLOW study . Int J Chron Obstruct (Pulmon Dis.) .2015 ;(10):2109-2120

58. 2015 Wang Tsai Yu ,Lo Yu Lun ,Chou Pai Chien ,Chung Fu Tsai ,Lin Shu Min ,Lin TY,Lin HC,Wang CH,Yu CT,Kuo HP. Associated bone mineral density and obstructive sleep apnea in chronic obstructive pulmonary disease . Int J Chron Obstruct Pulmon Dis. .2015 ;(10):231-237

59. 2015 Wang CH,Punde TH,Huang CD,Chou PC,Huang TT,Wu WH, Liu CH, Chung KF,Kuo HP. Fibrocyte trafficking in patients with chronic obstructive asthma and during an acute asthma exacerbation. . J Allergy Clin Immunol. .2015 ;(135):1154-1162

60. 2015 Punde TH,Wu WH,Lien PC ,Chang YL ,Kuo PH ,Chang MD, Lee KY, Huang CD, Kuo HP, Chan YF, Shih PC, Liu CH . A biologically inspired lung-on-a-chip device for the study of protein-induced lung inflammation . Integrative Biology .2015 ;(7):162-169

61. 2015 Fang YF ,Hsieh MH ,Chung FT ,Huang YK ,Chen GY ,Lin SM, Lin HC, Wang CH, Kuo HP. Flexible bronchoscopy with multiple modalities for foreign body removal in adults . PLoS One .2015 ;(10):e0118993-e0118993

62. 2015 Lin SM ,Chung FT ,Kuo CH ,Chou PC ,Wang TY ,Chang PJ, Lo YL, Huang CD, Lin HC, Wang CH, Kuo HP.. Circulating Angiopopietin-1 Correlates with the Clinical Course of Multiple Organ Dysfunction Syndrome and Mortality in Patients with Severe Sepsis . Medicine (Baltimore) .2015 ;(94):e878-e878

63. 2015 Lo CY,Charalambos M,Pankaj KB,Huang CD,Wang CH,Kuo HP,Chung KF. Increased phenotypic differentiation and reduced corticosteroid sensitivity of fibrocytes in severe asthma . Journal of Allergy and Clinical Immunology .2015 ;(135):1186-1195e6

64. 2015 Lo Yu Lun ,Ni Yung Lun ,Wang Tsai Yu ,Lin Ting Yu ,Li Hsueh Yu ,White DP, Lin JR, Kuo HP. Bispectral index in evaluating effects of sedation depth on drug-induced sleep endoscopy . Journal of Clinical Sleep Medicine .2015 ;(11):1011-1020

65. 2014 Kuo CH,Lin SM,Lee KY,Chung FT,Feng PH,Hsiung TC,Lo YL,Liu CY,Kuo HP. Algorithmic approach by endobronchial ultrasound-guided transbronchial needle aspiration for isolated intrathoracic lymphadenopathy: A study in a tuberculosis-endemic country . Journal of the Formosan Medical Association .2014 ;(113):527-534

66. 2014 Huang KH,Wang CH,Lin CH,Kuo HP. NF-κB repressing factor downregulates basal expression and mycobacterium tuberculosis induced IP-10 and IL-8 synthesis via interference with NF-κB in monocytes . Journal of Biomedical Science .2014 ;(21):71-71

67. 2014 Kuo CH,Lin SM,Lee KY,Chung FT,Lo YL,Hsiung TC,Liu CY,Kuo HP. Endobronchial ultrasound-guided transbronchial biopsy and brushing: A comparative evaluation for the diagnosis of peripheral pulmonary lesions . European Journal of Cardio-thoracic Surgery .2014 ;(45):894-898

68. 2014 Chiu KC,Chou YL,Hsu JY,Lin MS,Lin CH,Chou PC,Chou CL,Wang CH,Kuo HP. Comparison of the efficacy of ciclesonide with that of budesonide in mild to moderate asthma patients after step-down therapy: A randomised parallel-group study . npj Primary Care Respiratory Medicine .2014 ;(24):14010-14010

69. 2014 Wang TY,Lin SM,Shie SS,Chou PC,Huang CD,Chung FT,Kuo CH,Chang PJ,Kuo HP. Clinical characteristics and treatment outcomes of patients with low- and high-concentration isoniazid-monoresistant tuberculosis . PLoS One .2014 ;(9):e86316-e86316

70. 2014 Wang CH,Chung FT,Lin SM,Huang SY,Chou CL,Lee KY,Lin TY,Kuo HP. Adjuvant treatment with a mammalian target of rapamycin inhibitor, sirolimus, and steroids improves outcomes in patients with severe H1N1 pneumonia and acute respiratory failure . Critical Care Medicine .2014 ;(42):313-321

71. 2014 Hsu MF,Ho SC,Kuo HP,Wang JY,Tsai AC. Mini-nutritional assessment (MNA) is useful for assessing the nutritional status of patients with chronic obstructive pulmonary disease: A cross-sectional study . COPD: Journal of Chronic Obstructive Pulmonary Disease .2014 ;(11):325-332

72. 2014 Huang CD,Hsiung TC,Ho SC,Lee KY,Chan YF,Kuo LW,Lin SM,Wang CH,Lin HC,Kuo HP. PPARγ ligand ciglitazone inhibits TNFα-induced ICAM-1 in human airway smooth muscle cells. . Biomed J .2014 ;(37):191-198

73. 2014 Wang CH,Chou PC,Joa WC,Chen LF,Sheng TF,Ho SC,Lin HC,Huang CD,Chung FT,Chung KF,Kuo HP. Mobile-phone-based home exercise training program decreases systemic inflammation in COPD: a pilot study. . BMC Pulm Med .2014 ;(14):142-142

74. 2013 Kuo CH,Chung FT,Kuo HP. Infected bronchogenic cyst diagnosed by endobronchial ultrasound-guided transbronchial needle aspiration . Journal of the Formosan Medical Association .2013 ;(112):436-437

75. 2013 Weng CM,Chen BC,Wang CH,Feng PH,Lee MJ,Huang CD,Kuo HP,Lin CH. The endothelin a receptor mediates fibrocyte differentiation in chronic obstructive asthma the involvement of connective tissue growth factor . American Journal of Respiratory and Critical Care Medicine .2013 ;(188):298-308

76. 2013 Huang KH,Wang CH,Lee KY,Lin SM,Lin CH,Kuo HP. NF-κB repressing factor inhibits chemokine synthesis by peripheral blood mononuclear cells and alveolar macrophages in active pulmonary tuberculosis . PLoS One .2013 ;(8):e77789-e77789

77. 2013 Wang TY,Lo YL,Lee KY,Liu WT,Lin SM,Lin TY,Ni YL,Wang CY,Ho SC,Kuo HP. Nocturnal CPAP improves walking capacity in COPD patients with obstructive sleep apnoea . Respiratory Research .2013 ;(14):66-66

78. 2013 Hsieh MH,Chou PC,Chou CL,Ho SC,Joa WC,Chen LF,Sheng TF,Lin HC,Wang TY,Chang PJ,Wang CH,Kuo HP. Matrix Metalloproteinase-1 Polymorphism (-1607G) and Disease Severity in Non-Cystic Fibrosis Bronchiectasis in Taiwan . PLoS One .2013 ;(8):e66265-e66265

79. 2013 Liao KC,Pu SJ,Liu MS,Yang CW,Kuo HP. Development and implementation of a mini-clinical evaluation exercise (mini-CEX) program to assess the clinical competencies of internal medicine residents: From faculty development to curriculum evaluation . BMC Medical Education .2013 ;(13):31-31

80. 2013 Lin TY,Lo YL,Hsieh CH,Ni YL,Wang TY,Lin HC,Wang CH,Yu CT,Kuo HP. The Potential Regimen of Target-Controlled Infusion of Propofol in Flexible Bronchoscopy Sedation: A Randomized Controlled Trial . PLoS One .2013 ;(8):e62744-e62744

81. 2013 Oh YM,Bhome AB,Boonsawat W,Gunasekera KD,Madegedara D,Idolor L,Roa C,Kim WJ,Kuo HP,Wang CH,Lan le TT,Loh LC,Ong CK,Ng A,Nishimura M,Makita H,Silverman EK,Lee JS,Yang T,Lin Y,Wang C,Lee SD. Characteristics of stable chronic obstructive pulmonary disease patients in the pulmonology clinics of seven Asian cities . International Journal of COPD .2013 ;(8):31-39

82. 2013 Ho SC,Lin HC,Kuo HP,Chen LF,Sheng TF,Jao WC,Wang CH,Lee KY. Exercise training with negative pressure ventilation improves exercise capacity in patients with severe restrictive lung disease: A prospective controlled study . Respiratory Research .2013 ;(14):22-22

研究計畫

計畫名稱
113 絲氨酸蛋白酶抑制劑參與介白質6反式信令在氣喘患者呼吸道上皮細胞所造成的功能失常(2/3)
補助單位
國家科學及技術委員會

計畫名稱
112 絲氨酸蛋白酶抑制劑參與介白質6反式信令在氣喘患者呼吸道上皮細胞所造成的功能失常(1/3)
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國家科學及技術委員會

計畫名稱
112 貴機構依本會「補助國內研究生出席國際學術會議」申請費用補助案(研究生:醫學科學研究所博士班曾志傑君)
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111 血中的纖維細胞在嚴重氣喘患者扮演第二型細胞激素嶄新的細胞來源其臨床相關性與調控機制(3/3)
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國家科學及技術委員會

計畫名稱
110 血中的纖維細胞在嚴重氣喘患者扮演第二型細胞激素嶄新的細胞來源其臨床相關性與調控機制(2/3)
補助單位
科技部

計畫名稱
109 LTh(αk)應用於氣喘與過敏性鼻炎免疫調控機轉
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昱厚生技股份有限公司

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109 一項隨機分派、安慰劑組對照試驗,針對轉移性非小細胞肺癌受試者使用Pembrolizumab輔以MS-20治療之安全性及潛在療效探索
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中天生物科技股份有限公司

計畫名稱
109 FB704A藥物機制與藥效探索研究計畫
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合一生技股份有限公司

計畫名稱
109 血中的纖維細胞在嚴重氣喘患者扮演第二型細胞激素嶄新的細胞來源其臨床相關性與調控機制(1/3)
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科技部

計畫名稱
108 慢性阻塞性氣喘患者呼吸道上皮細胞所釋放的介白質33(IL-33)影響血液中成纖維細胞的趨化、增殖與分化作用之機轉(3/3)
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科技部

計畫名稱
107 推動新南向醫衛合作與產業鏈發展
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衛生福利部

計畫名稱
107 慢性阻塞性氣喘患者呼吸道上皮細胞所釋放的介白質33(IL-33)影響血液中成纖維細胞的趨化、增殖與分化作用之機轉(2/3)
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科技部

計畫名稱
106 慢性阻塞性氣喘患者呼吸道上皮細胞所釋放的介白質33(IL-33)影響血液中成纖維細胞的趨化、增殖與分化作用之機轉(1/3)
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科技部