1. |
2024
MAOB expression correlates with a favourable prognosis in prostate cancer, and its genetic variants are associated with the metastasis of the disease
. Journal of Cellular and Molecular Medicine
.2024
;(28):e18229
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2. |
2022
Activin A downregulates the CD69-MT2A axis via p38MAPK to induce erythroid differentiation that sensitizes BCR-ABL-positive cells to imatinib
. Experimental cell research
.2022
;(417):1-11
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3. |
2022
Ju-Fang Liu,Yinshen Wee,Shen-Dean Luo,Shwu-Fen Chang,Shihai Jia,Sheng-Wei Feng, Huei-Mei Huang, Jiann-Her Lin, Ching-Shuen Wang.
Proanthocyanidins-loaded complex coacervates-based drug delivery attenuates oral squamous cell carcinoma cells metastatic potential through down-regulating the Akt signaling pathway
. Frontiers in Oncology
.2022
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4. |
2020
Buyandelger B,Bar Eli E,Hung KS,Chen RM,Chiang YH,Liou JP, Huang HM, Wang JY*.
Histone deacetylase inhibitor MPT0B291 suppresses Glioma Growth in vitro and in vivo partially through acetylation of p53
. International Journal of Biological Sciences
.2020
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5. |
2019
Lee YC,Sue YM,Lee CK,Huang HM,He JJ,WangYS, JuanSH.
Synergistic effects of cAMP–dependent protein kinase A and AMP-activated protein kinase on lipolysis in kinsenoside-treated C3H10T1/2 adipocytes
. Phytomedicine
.2019
;(55):255-263
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6. |
2019
Lin CL,Huang HM,Hsieh CL,Fan CK,Lee YL..
Jagged1-expressing adenovirus-infected dendritic cells induce expansion of Foxp3+ regulatory T cells and alleviate T helper type 2-mediated allergic asthma in mice.
. Immunology
.2019
;(156):199-212
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7. |
2019
Chen YC,Chen BC,Huang HM,Lin SH,Lin CH.
Activation of PERK in ET-1- and thrombin-induced pulmonary fibroblast differentiation: Inhibitory effects of curcumin
. J Cell Physiol
.2019
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8. |
2019
Chiu SP,Batsaikhan B,Huang HM,Wang JY.
Application of Electric Cell-Substrate Impedance Sensing to Investigate the Cytotoxic Effects of Andrographolide on U-87 MG Glioblastoma Cell Migration and Apoptosis
. Sensors (Basel)
.2019
;(19)
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9. |
2018
Huang SY,Liu YH,Chen YJ,Yeh YY,Huang HM*.
CD69 partially inhibits apoptosis and erythroid differentiation via CD24, and their knockdown increase imatinib sensitivity in BCR-ABL-positive cells
. J Cell Physiol
.2018
;(233):7467-7479
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10. |
2018
Yang JM#,Huang HM#,Cheng JJ,Huang CL,Lee YC,Chiou CT, Huang HT, Huang NK, Yang YC.
LGK974, a PORCUPINE inhibitor, mitigates cytotoxicity in an in vitro model of Parkinson's disease by interfering with the WNT/β-CATENIN pathway
. Toxicology
.2018
;(410):65-72
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11. |
2018
Lee CH,Lin YF,Chen YC,Wong SM,Juan SH,Huang HM*.
MPT0B169 and MPT0B002, new tubulin inhibitors, induce growth inhibition, G2/M cell cycle arrest, and apoptosis in human colorectal cancer cells
. Pharmacology
.2018
;(102):262-271
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12. |
2018
Chiu HW,Chang JS,Lin HY,Lee HH,Kuei CH,Lin CH, Huang HM*, Lin YF*.
FBXL7 upregulation predicts a poor prognosis and associates with a possible mechanism for paclitaxel resistance in ovarian cancer
. J Clin Med
.2018
;(7):1-14
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13. |
2018
Shao-Ping C,Huang HM,Shen SC,Lee WR,Chen YC.
Nilotinib induction of melanogenesis via reactive oxygen species-dependent JNK activation in B16F0 mouse melanoma cells
. Exp Dermatol
.2018
;(27):1388-1394
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14. |
2017
Chiang CY,Lee CC,Fan CK,Huang HM,Chiang BL,Lee YL.
Osthole treatment ameliorates Th2-mediated allergic asthma and exerts immunomodulatory effects on dendritic cell maturation and function.
. Cell and Molecular Immunology
.2017
;(14):1-13
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15. |
2017
Yeh YY,Liou JP,Lee YL,Lin JY,Huang HM*.
MPT0B002, a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells
. Invest New Drugs
.2017
;(35):427-435
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16. |
2016
Wang CC,Liu HE,Lee YL,Huang YW,Chen YJ,Liou JP, Huang HM.
MPT0B169, a novel tubulin inhibitor, induces apoptosis in taxol-resistant acute myeloid leukemia cells through mitochondrial dysfunction and Mcl-1 downregulation
. Tumor Biology.
.2016
;(37):6065-6072
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17. |
2016
Wong SM,Liu FH,Lee YL,Huang HM*.
MPT0B169, a New Antitubulin Agent, Inhibits Bcr-Abl Expression and Induces Mitochondrion-Mediated Apoptosis in Nonresistant and Imatinib-Resistant Chronic Myeloid Leukemia Cells
. PLoS One
.2016
;(11):e0148093-e0148093
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18. |
2016
Chen CW,Lee YL,Liou JP,Liu YH,Liu CW,Chen TY, Huang HM*.
A novel tubulin polymerization inhibitor, MPT0B206, downregulates Bcr-Abl expression and induces apoptosis in imatinib-sensitive and imatinib-resistant CML cells
. Apoptosis
.2016
;(21):1008-1018
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19. |
2015
Shieh YH#,Huang HM#,Wang CC,Lee CC,Fan CK,Lee YL.
Zerumbone enhances the Th1 response and ameliorates ovalbumin-induced Th2 responses and airway inflammation in mice
. Int Immunopharmacol
.2015
;(24):383-391
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20. |
2015
Lee CC,Wang CC,Huang HM,Lin CL,Leu SJ,Lee YL.
Ferulic acid induces Th1 responses by modulating the function of dendritic cells and ameliorates Th2-mediated allergic airway inflammation in mice
. Evid Based Complement Alternat Med
.2015
;(2015):678487
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21. |
2014
Huang YW,Lee WH,Tsai YH,Huang HM*.
Activin A induction of erythroid differentiation sensitizes K562 chronic myeloid leukemia cells to a subtoxic concentration of imatinib (doi:10.1152/ajpcell.00130.2013)
. American Journal of Physiology - Cell Physiology
.2014
;(306):C37-44
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22. |
2014
Lee WH,Chung MH,Tsai YH,Chang JL,Huang HM*.
Interferon-γ suppresses activin A/NF-E2 induction of erythroid gene expression through the NF-κB/c-Jun pathway
. Am J Physiol Cell Physiol
.2014
;(306):C407-414
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23. |
2014
Chen CW,Chung MH,Chang JL,Liu CH,Huang HM*.
Role of c-Jun in Tumor Necrosis Factor-Alpha Inhibition of Activin A-Mediated Erythroid Gene Expression in Erythroleukemia K562 Cells
. J Exp Clin Med
.2014
;(6):222-227
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24. |
2013
Lee WH,Liu H Eugene,Chang JY,Liou JP,Huang HM.
MPT0B169, a New Tubulin Inhibitor, Inhibits Cell Growth and Induces G2/M Arrest in Nonresistant and Paclitaxel-Resistant Cancer Cells
. Pharmacology
.2013
;(92):90-98
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25. |
2013
Huang HM,Hsiao G,Fan CK,Lin CL,Leu SJ,Chiang BL, Lee YL.
Notch Ligand Delta-Like 4-Pretreated Dendritic Cells Alleviate Allergic Airway Responses by Enhancing IL-10 Production (doi:10.1371/journal.pone.0063613)
. PLOS ONE
.2013
;(8):1-14
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26. |
2013
Lee YL,Chen CW,Liu FW,Huang YW,Huang HM.
Aclacinomycin A sensitizes K562 chronic myeloid leukemia cells to imatinib through p38MAPK-mediated erythroid differentiation (doi:10.1371/journal.pone.0061939)
. PLOS ONE
.2013
;(8):1-9
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27. |
2011
Lin YF,Leu SJ,Huang HM,Tsai YH.
Selective Activation of Specific PKC Isoforms Dictating the Fate of CD14+ Monocytes Towards Differentiation or Apoptosis
. Journal of Cellular Physiology
.2011
;(226):122-131
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28. |
2011
Chiu LH,Yeh TS,Huang HM,Leu SJ,Yang CB,Tsai YH.
Diverse effects of type II collagen on osteogenic and adipogenic differentiation of mesenchymal stem cells
. Journal of Cellular Physiology (accepted)
.2011
;(0):0-0
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29. |
2010
Lee WH,Liu FH,Lee YL,Huang HM*.
Interferon-alpha induces the growth inhibition of human T cell leukemia line Jurkat through p38alpha and p38beta
. Journal of Biochemistry
.2010
;(147):645-650
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30. |
2010
Huang HM*,Li YC,Chung MH.
Activin A induction of erythroid differentiation through MKK6-p38α/p38β pathway is inhibited by follistatin
. Journal of Cellular Physiology
.2010
;(223):687-694
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31. |
2009
Huang HM*,Liu JC.
c-Jun blocks cell differentiation but not growth inhibition or apoptosis of chronic myelogenous leukemia cells induced by STI571 and by histone deacetylase inhibitors
. Journal of Cellular Physiology
.2009
;(218):568-574
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32. |
2009
Lee WH,Liu FH,Lin YC,Huang SY,Lin H,Liao WJ, Huang HM*.
JAK pathway induction of c-Myc critical to IL-5 stimulation of cell proliferation and inhibition of apoptosis
. Journal of Cellular Biochemistry
.2009
;(106):929-936
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33. |
2008
Chen CH,Lin YC,Liu FH,Chang JL,Huang HM.
Basic fibroblast growth factor inhibits p38-mediated cell differentiation and growth inhibition by activin A but not by histone deacetylase inhibitors in CML cells
. Annals of Hematology
.2008
;(87):175-182
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34. |
2007
Hsieh CW,Lan JL,Meng Q,Cheng YW,Huang HM,Tsai JJ.
Eosinophil Apoptosis Induced by Fungal Immunomodulatory Peptide-fve via Reducing IL-5 Alpha receptor
. J Formos Med Assoc
.2007
;(106):36-43
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35. |
2006
Huang HM,Lee YL,Chang TW.
JAK1 N-terminus binds to conserved Box1 and Box2 motifs of cytokine receptor common beta subunit but signal activation requires JAK1 C-terminus
. J. Cell Biochem.
.2006
;(99):1078-1084
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36. |
2006
Huang HM,Chiou HY,Chang JL.
Activin A induces erythroid gene expressions and inhibits mitogenic cytokine-mediated K562 colony formation by activating p38 MAPK
. J. Cell Biochem.
.2006
;(98):789-797
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37. |
2006
Chen CH,Hsu YH,Sue YM,Hou CC,Lee HM,Huang HM, Chen TH.
Src homology 2-containing phosphotyrosine phosphatase regulates endothelin-1-induced epidermal growth factor receptotransactivation in rat renal tubular cell NRK-52Er
. Pflug. Arch. Eur. J. Phy.
.2006
;(452):16-24
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38. |
2005
Huang HM,Lin YL,Chen CH,Chang TW.
Simultaneous activation of JAK1 and JAK2 confers IL-3 independent growth on Ba/F3 pro-B cells
. J. Cell Biochem.
.2005
;(96):361-375
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39. |
2005
Juan SH,Yen JY,Lee HM,Huang HM.
IL-5 inhibits apoptosis by up-regulation of c-myc expression in human hematopoietic cells
. Ann. N.Y. Acad Sci.
.2005
;(1042):481-487
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40. |
2005
Huang HM,Liang YC,Cheng TH,Juan SH.
Potential Mechanism of Blood Vessels Protection by Resveratrol, a Red Wine Component
. Ann. N.Y. Acad Sci.
.2005
;(1042):349-356
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41. |
2004
Huang HM,Chang TW,Liu JC.
Basic fibroblast growth factor antagonizes activin A-mediated growth inhibition and hemoglobin synthesis in K562 cells by activating ERK1/2 and deactivating p38 MAP kinase.
. Biochem Biophys Res Commun.
.2004
;(320):1247-1252
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42. |
2000
Huang HM, Huang CJ, Jeffrey Yen JY.
mcl-1 Is a Common Target of Stem Cell Factor and Interleukin 5 for the Apoptosis Prevention Activity via MEK/MAPK and PI-3K/Akt Pathways
. Blood
.2000
;(96):1764-1771
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43. |
1999
Lee SF, Huang HM, Chao JR, Lin S, Yang-Yen HF ,Yen JY.
Cytokine Receptor Common β Chain as a Potential Activator of Cytokine Withdrawal-Induced Apoptosis
. Mol. Cell. Biol.
.1999
;(19):7399-7409
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44. |
1999
Huang HM, Li JC, Hsieh YC, Yang-Yen HF, Jeffrey Yen JY.
Optimal Proliferation of a Hematopoietic Progenitor Cell Line Requires Either Costimulation With Stem Cell Factor or Increase of Receptor Expression That Can Be Replaced by Overexpression of Bcl-2
. Blood
.1999
;(93):2569-2577
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45. |
1998
Chao JR, Wang JM, Lee SF, Peng HW, Lin YH, Chou CH, Li JC, Huang HM, Chou CK, Kuo ML, Jeffrey Yen JY, Yang-Yen HF.
mcl-1 Is an Immediate-Early Gene Activated by the Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Signaling Pathway and Is One Component of the GM-CSF Viability Response
. Mol. Cell. Biol.
.1998
;(18):4883-4898
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