李愛薇(Lee, Ai-Wei) 副教授

Email
ammielee@tmu.edu.tw
現   職
解剖學暨細胞生物學科 副教授

學經歷

學 歷

畢業學校與學位[修業時間]
臺北醫學大學醫學科學研究所博士班 博士
2005/09/01~2013/01/31
國立陽明大學解剖學研究所 碩士
1997/06/01~1999/07/01
私立弘光醫事護理專科學校護理科
1992/09/01~1994/06/01

本校學術經歷

任職單位與職稱[起迄時間]
解剖學暨細胞生物學科副教授
2019/02/01~
解剖學暨細胞生物學科助理教授
2014/08/01~2019/01/31
解剖學科助理教授
2013/08/01~2014/07/31
解剖學科講師
1999/08/01~2013/07/31

本校兼職教學行政經歷

服務單位與職稱[起迄時間]
無資料!

其它經歷

任職單位與職稱[起迄時間]
無資料!

專長與研究領域

學門領域
皮膚科
解剖
學術專長
電泳(electrophoresis)
免疫組織化學(immunohistochemistry)
細胞培養
RT-PCR
動物實驗

論文著作

清冊下載


1. 2024 Ginkgetin effectively mitigates collagen and AA-induced platelet activation via PLCγ2 but not cyclic nucleotide-dependent pathway in human . J Cell Mol Med .2024

2. 2024 Chen CC,Lin YA,Liu KT,Huang CY,Shih CM,Lee YT,Pan JL ,Lee AW. Navigating SARS-CoV-2-related immunopathology in Crohn’s disease: from molecular mechanisms to therapeutic challenges. . Virology Journal .2024

3. 2023 In silico analysis to identify miR-1271-5p/PLCB4 (phospholipase C Beta 4) axis mediated oxaliplatin resistance in metastatic colorectal cancer . Scientific Reports .2023

4. 2023 CWH43 Is a Novel Tumor Suppressor Gene with Negative Regulation of TTK in Colorectal Cancer . Int. J. Mol. Sci. .2023 ;(24):15262

5. 2022 Annoying Psoriasis and Atopic Dermatitis: A Narrative Review . Int. J. Mol. Sci. .2022 ;(23):4898

6. 2022 Lee AW,Chang PL, Liaw SK,Lu CH,Chen JK. Inflammation-Responsive Nanovalves of Polymer-Conjugated Dextran on a Hole Array of Silicon Substrate for Controlled Antibiotic Release . polymers .2022

7. 2021 Fasih Bintang Ilhami,, Ai Chung, Yihalem Abebe Alemayehu,, Ai-Wei Lee,Jem-Kun Chen, ,Juin-Yih Lai,Chih-Chia Cheng. Self-assembled nanoparticles formed via complementary nucleobase pair interactions between drugs and nanocarriers for highly efficient tumor-selective chemotherapy . Materials Chemistry Frontiers .2021

8. 2021 Hydrogen Bond Strength-Mediated Self-Assembly of Supramolecular Nanogels for Selective and Effective Cancer Treatment . Biomacromolecules .2021

9. 2021 Photoreactive Cytosine-Functionalized Self-Assembled Micelles with Enhanced Cellular Uptake Capability for Efficient Cancer Chemotherapy . Biomacromolecules .2021

10. 2020 Chun-Ming Shih,Chang-Cyuan Chen,Chen-Kuo Chu,Kuo-Hsien Wang,Chun-Yao Huang,Ai-Wei Lee. The Roles of Lipoprotein in Psoriasis . International Journal of Molecular Sciences .2020

11. 2020 Preparation of Biofiltration Membranes by Coating Electrospun Polyacrylonitrile Fiber Membranes with Layer-by-layer Supermolecular Polyelectrolyte Films . Colloids and Surfaces B: Biointerfaces .2020

12. 2020 Hydrogen-bonded supramolecular micelle-mediated drug delivery enhances the efficacy and safety of cancer chemotherapy . Polymer Chemistry .2020

13. 2020 Optical assay of trypsin using a one-dimensional plasmonic grating of gelatin-modified poly(methacrylic acid) . Microchimica Acta .2020

14. 2020 Lycopene inhibit IMQ-induced psoriasis-like inflammation by inhibiting ICAM-1 production in mice . Polymers .2020

15. 2020 Cytosine-Functionalized Supramolecular Polymer-Mediated Cellular Behavior and Wound Healing . Biomacromolecules .2020

16. 2020 Self-Assembled Supramolecular Micelles with pH-Responsive Properties for More Effective Cancer Chemotherapy . ACS Biomaterials .2020

17. 2019 Belete Tewabe Gebeyehu,Ai-Wei Lee,Shan-You Huang,Adem Ali Muhabie,Juin-Yih Lai,Duu-Jong Lee,Chih-Chia Cheng. Highly stable photosensitive supramolecular micelles for tunable, efficient controlled drug release . European Polymer Journal .2019 ;(110):403-412

18. 2019 Chih-Chia Cheng, Adem Ali Muhabie,Shan-You Huang, Cheng-You Wu,Belete Tewabe Gebeyehu, Ai-Wei Lee,Juin-Yih La,Duu-Jong Lee. Dual Stimuli-Responsive Supramolecular Boron Nitride with Tunable Physical Properties for Controlled Drug Delivery . Nanoscale .2019 ;(11):10393-10410

19. 2019 Chih-Chia Cheng,Jyun-Jie Huang,Ai-Wei Lee,Shan-You Huang,Chien-Yu Huang,Juin-Yih Lai. Highly Effective Photocontrollable Drug Delivery Systems Based on Ultrasensitive Light-Responsive Self-Assembled Polymeric Micelles: An In Vitro Therapeutic Evaluation . ACS Appl. Bio Mater .2019 ;(2):2162-2170

20. 2018 Ai-Wei Lee,Fu-Xiang Lin,Po-Li Wei,Guo Jian-Wei,Jem-Kun Chen*. Binary-blend fibber-based capture assay of circulating tumor cells for clinical diagnosis of colorectal cancer . Journal of Nanobiotechnology .2018 ;(16)

21. 2018 Huang LC,Tam KW,Liu WN,Lin CY,Hsu KW,Hsieh WS, Chi WM,Lee AW,Yang JM,Ln CL,Lee CH. CRISPR/Cas9 genome editing of Epidermal Growth Factor Receptor sufficiently abolished oncogenicity in Anaplastic Thyroid cancer. . Disease Markers .2018

22. 2018 Self-Assembled pH-Responsive Polymeric Micelles for Highly Efficient, Noncytotoxic Delivery of Doxorubicin Chemotherapy To Inhibit Macrophage Activation: In Vitro Investigation . Biomacromolecules .2018

23. 2018 Dual Stimuli-Responsive Nucleobase-Functionalized Polymeric Systems as Efficient Tools for Manipulating Micellar Self-Assembly Behavior . Macromolecules .2018

24. 2018 Shih CM, Huang CY, Huang CY,Wang KH,Wei PL,Chang YJ,Fong TH,Pan JL,Lee AW. A dipeptidyl peptidase‐4 inhibitor promotes wound healing in normoglycemic mice by modulating keratinocyte activity . Experimental Dermatology .2018

25. 2018 Shih CM, Huang CY,Wang KH,Huang CY,Wei PL,Chang YJ, Hsieh CK, Liu KT, Lee AW. Oxidized low-density lipoprotein-deteriorated psoriasis is associated with the upregulation of LOX-1 receptor and IL-23 expression in vivo and in vitro . International Journal of Molecular Sciences .2018 ;(19)

26. 2017 Li-You Chen,Ting-Yi Renn,Wen-Chieh Liao,Fu-Der Mai,,Ying-Jui Ho,,George Hsiao, Ai-Wei Lee,. Melatonin Successfully Rescues Hippocampal Bioenergetics and Improves Cognitive Function following Drug Intoxication by Promoting Nrf2-ARE Signaling Activity . Journal of Pineal Research .2017

27. 2017 Jun-Ru Zeng,Chih-Chia Cheng,Ai-Wei Lee,Po-Li Wei,Jem-Kun Chen. Visualization platform of one-dimensional gratings of tethered polyvinyltetrazole brushes on silicon surfaces for sensing of Cr(III) . .2017

28. 2017 Yi-Zu Liu,Karthikeyan Maniva,Ai-Wei Lee,Yan-Jiun Huang,Po-Li Wei,Jem-Kun Chen. Identification of DNA single-base mismatches by resistivity of poly(N-isopropylacrylamide)-block-ssDNA copolymer brush films at dual temperatures . .2017

29. 2016 Kaoa TH,Su SK,Su CI,Lee AW,Chen JK. Polyacrylonitrile microscaffolds assembled from mesh structures of aligned electrospun nanofibers as high-efficiency particulate air filters . Aerosol Science and Technology .2016

30. 2016 Lee AW,Hsu CC,Liu YZ,Wei PL,Chen JK. Supermolecules of poly(N-isopropylacrylamide) complexating Herring sperm DNA with bio-multiple hydrogen bonding . Colloids and Surfaces B: Biointerfaces .2016

31. 2016 Tseng HC,Lee AW,Wei PL,Chang YJ,Chen JK. Clinical Diagnosis of Colorectal Cancer Using Electrospun Triple-Blend Fibrous Mat–Based Capture Assay of Circulating Tumor Cells . Journal of Materials Chemistry B .2016

32. 2015 Yi-Jie Kuoa,Yung-Kai Huang,Hsiu-Chu Chouc,Man-Hui Paic,Ai-Wei Leec,Hung-Ming Chang. Reduced dental calcium expression and dental mass in chronic sleepdeprived rats: Combined EDS, TOF-SIMS, and micro-CT analysis . Applied Surface Science .2015 ;(*):*-*

33. 2014 Zhou GY,Cheng CC,Chi-JungChang,Lee AW,Chen JK. Label-Free DNA Detection Using Two-Dimensional Periodic Relief Grating as a Visualized Platform for Diagnosis of Breast Cancer Recurrence after Surgery . Biosensors and Bioelectronics (Accept) .2014 ;(54):35-41

34. 2014 Jem-Kun Chen,Gang-Yan Zhou,Chi-Jung Chang,Ai-Wei Lee,Feng-Chih Chang. Two-Dimensional Periodic Relief Gratings as a Versatile Platform for Label-Free Specifi c DNA Detection . Adv. Mater. Interfaces .2014 ;(**):**-**

35. 2014 Yang HW,Chen JK,Kuo SW,Lee AW. Degradable coronas comprising polyelectrolyte complexes of PDMAEMA and gelatin for pH-triggered antibiotic release . polymer .2014 ;(55):2678-2687

36. 2014 Zhou GY,Lee AW,Chang JY,Huang CH,Chen JK*. Fabrication of metamaterial absorber using polymer brush – gold nanoassemblies for visualizing the reversible pH-responsiveness . Journal of Materials Chemistry c .2014 ;(**):**-**

37. 2014 Yang HW,Lee AW,Huang CH,Chen JK*. Characterization of poly(N-isopropylacrylamide)–nucleobase supramolecular complexes featuring bio-multiple hydrogen bonds† . Soft Matter .2014 ;(**):**-**

38. 2013 Chen HC,Hsu PW,Tzaan WC,Lee AW*. Effects of combined administration of vitamins C and E on oxidative stress status and programmed cell deaths in experimental spinal cord injury(accept) . Spinal Cord .2013 ;(00):00-00

39. 2012 Ai-Wei Lee,Chun-Yao Huang,Chun-Ming Shih,Nen-Chung Chang,Nai-Wen Tsao,Yu-Jia Chang, Tsorng-Harn Fong, Feng-Yen Lin. Ursolic acid attenuates HMGB1-induced LOX-1 expression in vascular endothelial cells in vitro and inhibits atherogenesis in hypercholesterolemic mice in vivo . Endocrine & Metabolic Agents in Medicinal Chemistry (Formerly 'Current Medicinal Chemistry - Immunology, Endocrine and Metabolic Agents').( .2012 ;(()):()-()

40. 2012 Huang, Chun-Yao,Shih, Chun-Ming,Lin, Yi-Wen,Tsao, Nai-Wen,Huang, Po-Hsun,Lee, Ai-Wei , Lin, Feng-Yen. Dipeptidyl peptidase-4 inhibitor improves neovascularization by increasing circulating endothelial progenitor cells . British Journal of Pharmacolo​gy .2012 ;(()):()-()

41. 2011 Shien-Chih Chen,Tsorng-harn Fong,Ai-Wei Lee,Wen-Ta Chiu. Autophagy is activated in injured neurons and inhibited by methylprednisolone after experimental spinal cord injury . Spine .2011 ;(**):**-**

42. 2010 Lee YW,Lin JA,Chang CC,Chen YH,Liu PL,Lee AW, Jui-Chi. Ginkgo biloba extract suppresses endotoxin-mediated monocyte activation by inhibiting nitric oxide- and tristetraprolin-mediated toll-like receptor 4 expression . Journal of Nutritional Biochemistry(Accepted) .2010

43. 2010 Lee AW,Chen TL,Shih CM,Huang CY,Tsao NW,Chang NC, Chen YH, Lin FY. Ursolic Acid Induces Allograft Inflammatory Factor-1 Expression via a Nitric Oxide-related Mechanism and Increases Neovascularization . Journal of Agriculture and food chemistry. .2010 ;(58):12941-12949

44. 2005 Jiang-Shieh YF,Yeh KY,Wu CH,Wei IH,Chang CY,Lee AW,PaiM,Chien HF,Tsai RY,Chang ML. Responses of Microglia In Vitro to the Gram-Positive Bacterial Component, Lipoteichoic Acid . Journal of Neuroscience Research .2005 ;(82):515-524

45. 2004 Shih YH,Lee AW,Huang YH,Ko MH,Fu YS. GABAergic Neuron Death in the Striatum Following Kainate-induced Damage of Hippocampal Neurons:Evidence for the Role of NO in Locomotion . International Journal of Neuroscience .2004 ;(114):1119-1132

46. 2001 Tsorng-Harn Fong, Ching-Hsiang Wu, E-Wen Liao, Chiu-Yun Chang, Man-Hui Pai, Ruei-Jen Chiou, and Ai-Wei Lee.. Association of Globular b-Actin with Intracellular Lipid Droplets in Rat Adrenocortical Cells and Adipocytes . Biochemical and Biophysical Research Communications .2001 ;(289):1168-1174


1. 2009 Lee AW,Fong TH,Yang ZL,Tsai HY,Lin FY. GroEL,A heat shock protein of Chlamydia pneumonia,impairs human early and late endothelial progenitor cells function . The 24th joint annual conference of biomedical science .2009

研究計畫

計畫名稱
112 「補助國內研究生出席國際學術會議」2024美國癌症研究協會年會(研究生:醫學科學研究所博士班李承錦君)
補助單位
國家科學及技術委員會

計畫名稱
111 超分子聚合物微胞應用於藥物控制釋放和癌症治療
補助單位
臺北醫學大學

計畫名稱
110 探討牙周病對牛皮癬之影響與治療用藥策略性之研究
補助單位
科技部

計畫名稱
109 自修復超分子聚合物於組織工程之應用
補助單位
臺北醫學大學

計畫名稱
108 探討引發牛皮癬相關的生物指標
補助單位
科技部

計畫名稱
108 生物可降解性高分子奈米複合材料於組織培養之應用
補助單位
臺北醫學大學

計畫名稱
108 探討高密度脂蛋白與藥物多效性對牛皮癬之影響與治療用藥策略性之研究
補助單位
科技部

計畫名稱
107 以舊藥新用的概念 探討牛皮癬治癒之可行性研究
補助單位
科技部

計畫名稱
106 氧化低密度脂蛋白對牛皮癬發生之影響以及使他汀類藥膏用於治療牛皮癬之可行性研究
補助單位
科技部

計畫名稱
102 探討DPP-IV抑制劑對傷口癒合過程中血管新生之影響
補助單位
臺北醫學大學附設醫院

計畫名稱
102 探討糖尿病藥物DPP-4抑制劑對傷口癒合的影響
補助單位
科技部

計畫名稱
102 TMU102-AE1-B33
補助單位
臺北醫學大學新聘教師計畫

計畫名稱
91 探討藥物YC-1誘發脂肪細胞發生脂解作用的機轉
補助單位
臺北醫學大學

計畫名稱
90 數種抗氧化劑影響發炎性細胞激素對微膠質細胞誘發一氧化氮生成及活體腦部氧化傷害之探討
補助單位
臺北醫學大學